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Drug Metabolism & Disposition

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Table of Contents

July 01, 2002; Volume 30,Issue 7

Articles

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    Phosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug Metabolism
    Vikram Arora, Melissa L. Cate, Chandramallika Ghosh and Patrick L. Iversen
    Drug Metabolism and Disposition July 2002, 30 (7) 757-762; DOI: https://doi.org/10.1124/dmd.30.7.757
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    Intestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1
    Feng R. Luo, Pankaj V. Paranjpe, Ailan Guo, Eric Rubin and Patrick Sinko
    Drug Metabolism and Disposition July 2002, 30 (7) 763-770; DOI: https://doi.org/10.1124/dmd.30.7.763
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    The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
    Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
    Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
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    Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
    Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
    Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
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    Identification of Human Hepatic Cytochrome P450 Sources of N-alkylprotoporphyrin IX after Interaction with Porphyrinogenic Xenobiotics, Implications for Detection of Xenobiotic-Induced Porphyria in Humans
    James A. Lavigne, Kanji Nakatsu and Gerald S. Marks
    Drug Metabolism and Disposition July 2002, 30 (7) 788-794; DOI: https://doi.org/10.1124/dmd.30.7.788
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    CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
    Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
    Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
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    In Vitro Interactions between a Potential Muscle Relaxant E2101 and Human Cytochromes P450
    Zhi-Yi Zhang, Belinda M. King, Nevena N. Mollova and Y. Nancy Wong
    Drug Metabolism and Disposition July 2002, 30 (7) 805-813; DOI: https://doi.org/10.1124/dmd.30.7.805
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    The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
    Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
    Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
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    Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
    R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
    Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
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    Measurement of Michaelis Constants for Cytochrome P450-Mediated Biotransformation Reactions Using a Substrate Depletion Approach
    R. Scott Obach and Anne E. Reed-Hagen
    Drug Metabolism and Disposition July 2002, 30 (7) 831-837; DOI: https://doi.org/10.1124/dmd.30.7.831
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    Tissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in Rats
    James M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. Klaassen
    Drug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
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    Cytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.
    David M. Stresser, Stephanie D. Turner, Andrew P. Blanchard, Vaughn P. Miller and Charles L. Crespi
    Drug Metabolism and Disposition July 2002, 30 (7) 845-852; DOI: https://doi.org/10.1124/dmd.30.7.845
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    Contribution of CYP3A4, CYP2B6, and CYP2C9 Isoforms toN-Demethylation of Ketamine in Human Liver Microsomes
    Youssef Hijazi and Roselyne Boulieu
    Drug Metabolism and Disposition July 2002, 30 (7) 853-858; DOI: https://doi.org/10.1124/dmd.30.7.853

Letter to the Editor

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    α1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral Regimens
    Marta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di Perri
    Drug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
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Drug Metabolism and Disposition: 30 (7)
Drug Metabolism and Disposition
Vol. 30, Issue 7
1 Jul 2002
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