Index by author
July 01, 2002; Volume 30,Issue 7
A
Arora, Vikram
- You have accessPhosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug MetabolismVikram Arora, Melissa L. Cate, Chandramallika Ghosh and Patrick L. IversenDrug Metabolism and Disposition July 2002, 30 (7) 757-762; DOI: https://doi.org/10.1124/dmd.30.7.757
B
Back, David J.
- You have accessα1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral RegimensMarta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di PerriDrug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
Baillie, Thomas A.
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
Blanchard, Andrew P.
- You have accessCytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.David M. Stresser, Stephanie D. Turner, Andrew P. Blanchard, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition July 2002, 30 (7) 845-852; DOI: https://doi.org/10.1124/dmd.30.7.845
Boffito, Marta
- You have accessα1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral RegimensMarta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di PerriDrug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
Bonora, Stefano
- You have accessα1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral RegimensMarta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di PerriDrug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
Boulieu, Roselyne
- You have accessContribution of CYP3A4, CYP2B6, and CYP2C9 Isoforms toN-Demethylation of Ketamine in Human Liver MicrosomesYoussef Hijazi and Roselyne BoulieuDrug Metabolism and Disposition July 2002, 30 (7) 853-858; DOI: https://doi.org/10.1124/dmd.30.7.853
Brady, James M.
- You have accessTissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in RatsJames M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. KlaassenDrug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
Buist, Susan C.
- You have accessTissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in RatsJames M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. KlaassenDrug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
Burn, Tim
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
C
Calam, A.
- You have accessEvaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase InhibitorR. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. SnelDrug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
Carroll, Kathy
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
Cate, Melissa L.
- You have accessPhosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug MetabolismVikram Arora, Melissa L. Cate, Chandramallika Ghosh and Patrick L. IversenDrug Metabolism and Disposition July 2002, 30 (7) 757-762; DOI: https://doi.org/10.1124/dmd.30.7.757
Cherrington, Nathan J.
- You have accessTissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in RatsJames M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. KlaassenDrug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
Chitty, Dawn
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
Chiu, Shuet-Hing L.
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
Chiu, Shuet-Hing Lee
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
Christ, Dave
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
Colandrea, Vincent J.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
Colletti, Adria E.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
Crespi, Charles L.
- You have accessCytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.David M. Stresser, Stephanie D. Turner, Andrew P. Blanchard, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition July 2002, 30 (7) 845-852; DOI: https://doi.org/10.1124/dmd.30.7.845
Cunningham, Mark
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
D
Di Perri, Giovanni
- You have accessα1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral RegimensMarta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di PerriDrug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
Doss, George A.
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
Downey, April
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
F
Faucette, Stephanie
- You have accessThe Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human HepatocytesCeleste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyseDrug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
Feeney, William P.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
G
Gan, Liang-Shang
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
Garner, J. V.
- You have accessEvaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase InhibitorR. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. SnelDrug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
Garner, R. C.
- You have accessEvaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase InhibitorR. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. SnelDrug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
Ghosh, Chandramallika
- You have accessPhosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug MetabolismVikram Arora, Melissa L. Cate, Chandramallika Ghosh and Patrick L. IversenDrug Metabolism and Disposition July 2002, 30 (7) 757-762; DOI: https://doi.org/10.1124/dmd.30.7.757
Gilbert, Darryl
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
- You have accessThe Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human HepatocytesCeleste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyseDrug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
Goris, I.
- You have accessEvaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase InhibitorR. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. SnelDrug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
Graham, Richard
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
Gregory, S.
- You have accessEvaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase InhibitorR. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. SnelDrug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
Guo, Ailan
- You have accessIntestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1Feng R. Luo, Pankaj V. Paranjpe, Ailan Guo, Eric Rubin and Patrick SinkoDrug Metabolism and Disposition July 2002, 30 (7) 763-770; DOI: https://doi.org/10.1124/dmd.30.7.763
H
Hamilton, Geraldine
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
- You have accessThe Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human HepatocytesCeleste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyseDrug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
Hartley, Dylan P.
- You have accessTissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in RatsJames M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. KlaassenDrug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
Hawke, Roy L.
- You have accessThe Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human HepatocytesCeleste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyseDrug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
Hijazi, Youssef
- You have accessContribution of CYP3A4, CYP2B6, and CYP2C9 Isoforms toN-Demethylation of Ketamine in Human Liver MicrosomesYoussef Hijazi and Roselyne BoulieuDrug Metabolism and Disposition July 2002, 30 (7) 853-858; DOI: https://doi.org/10.1124/dmd.30.7.853
Hoggard, Patrick G.
- You have accessα1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral RegimensMarta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di PerriDrug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
I
Iliff, Susan A.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
Iversen, Patrick L.
- You have accessPhosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug MetabolismVikram Arora, Melissa L. Cate, Chandramallika Ghosh and Patrick L. IversenDrug Metabolism and Disposition July 2002, 30 (7) 757-762; DOI: https://doi.org/10.1124/dmd.30.7.757
J
Jolley, Summer
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
- You have accessThe Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human HepatocytesCeleste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyseDrug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
K
Keohane, Carol A.
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
Keohane, Carol Ann
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
Kim, Sean
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
King, Belinda M.
- You have accessIn Vitro Interactions between a Potential Muscle Relaxant E2101 and Human Cytochromes P450Zhi-Yi Zhang, Belinda M. King, Nevena N. Mollova and Y. Nancy WongDrug Metabolism and Disposition July 2002, 30 (7) 805-813; DOI: https://doi.org/10.1124/dmd.30.7.805
Klaassen, Curtis D.
- You have accessTissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in RatsJames M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. KlaassenDrug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
Kwei, Gloria Y.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
L
Laenen, A. A. E.
- You have accessEvaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase InhibitorR. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. SnelDrug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
Lavigne, James A.
- You have accessIdentification of Human Hepatic Cytochrome P450 Sources of N-alkylprotoporphyrin IX after Interaction with Porphyrinogenic Xenobiotics, Implications for Detection of Xenobiotic-Induced Porphyria in HumansJames A. Lavigne, Kanji Nakatsu and Gerald S. MarksDrug Metabolism and Disposition July 2002, 30 (7) 788-794; DOI: https://doi.org/10.1124/dmd.30.7.788
LeCluyse, Edward
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
LeCluyse, Edward L.
- You have accessThe Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human HepatocytesCeleste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyseDrug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
Leong, D.
- You have accessEvaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase InhibitorR. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. SnelDrug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
Li, Ning
- You have accessTissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in RatsJames M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. KlaassenDrug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
Lin, Jianrong
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
Lindley, Celeste
- You have accessThe Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human HepatocytesCeleste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyseDrug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
Luo, Feng R.
- You have accessIntestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1Feng R. Luo, Pankaj V. Paranjpe, Ailan Guo, Eric Rubin and Patrick SinkoDrug Metabolism and Disposition July 2002, 30 (7) 763-770; DOI: https://doi.org/10.1124/dmd.30.7.763
Luo, Gang
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
M
Madan, Ajay
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
Marks, Gerald S.
- You have accessIdentification of Human Hepatic Cytochrome P450 Sources of N-alkylprotoporphyrin IX after Interaction with Porphyrinogenic Xenobiotics, Implications for Detection of Xenobiotic-Induced Porphyria in HumansJames A. Lavigne, Kanji Nakatsu and Gerald S. MarksDrug Metabolism and Disposition July 2002, 30 (7) 788-794; DOI: https://doi.org/10.1124/dmd.30.7.788
Mathvink, Robert J.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
McCune, Jeannine S.
- You have accessThe Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human HepatocytesCeleste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyseDrug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
Meuldermans, W.
- You have accessEvaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase InhibitorR. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. SnelDrug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
Miller, Randall R.
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
Miller, Randy R.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
Miller, Vaughn P.
- You have accessCytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.David M. Stresser, Stephanie D. Turner, Andrew P. Blanchard, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition July 2002, 30 (7) 845-852; DOI: https://doi.org/10.1124/dmd.30.7.845
Mollova, Nevena N.
- You have accessIn Vitro Interactions between a Potential Muscle Relaxant E2101 and Human Cytochromes P450Zhi-Yi Zhang, Belinda M. King, Nevena N. Mollova and Y. Nancy WongDrug Metabolism and Disposition July 2002, 30 (7) 805-813; DOI: https://doi.org/10.1124/dmd.30.7.805
Mudra, Daniel
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
N
Nakatsu, Kanji
- You have accessIdentification of Human Hepatic Cytochrome P450 Sources of N-alkylprotoporphyrin IX after Interaction with Porphyrinogenic Xenobiotics, Implications for Detection of Xenobiotic-Induced Porphyria in HumansJames A. Lavigne, Kanji Nakatsu and Gerald S. MarksDrug Metabolism and Disposition July 2002, 30 (7) 788-794; DOI: https://doi.org/10.1124/dmd.30.7.788
Naylor, Elizabeth M.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
Ngui, Jason S.
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
O
Obach, R. Scott
- You have accessMeasurement of Michaelis Constants for Cytochrome P450-Mediated Biotransformation Reactions Using a Substrate Depletion ApproachR. Scott Obach and Anne E. Reed-HagenDrug Metabolism and Disposition July 2002, 30 (7) 831-837; DOI: https://doi.org/10.1124/dmd.30.7.831
P
Paranjpe, Pankaj V.
- You have accessIntestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1Feng R. Luo, Pankaj V. Paranjpe, Ailan Guo, Eric Rubin and Patrick SinkoDrug Metabolism and Disposition July 2002, 30 (7) 763-770; DOI: https://doi.org/10.1124/dmd.30.7.763
Parkinson, Andrew
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
R
Raiteri, Riccardo
- You have accessα1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral RegimensMarta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di PerriDrug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
Reed-Hagen, Anne E.
- You have accessMeasurement of Michaelis Constants for Cytochrome P450-Mediated Biotransformation Reactions Using a Substrate Depletion ApproachR. Scott Obach and Anne E. Reed-HagenDrug Metabolism and Disposition July 2002, 30 (7) 831-837; DOI: https://doi.org/10.1124/dmd.30.7.831
Rizzo, Christopher
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
Rubin, Eric
- You have accessIntestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1Feng R. Luo, Pankaj V. Paranjpe, Ailan Guo, Eric Rubin and Patrick SinkoDrug Metabolism and Disposition July 2002, 30 (7) 763-770; DOI: https://doi.org/10.1124/dmd.30.7.763
S
Sciolè, Katiusha
- You have accessα1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral RegimensMarta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di PerriDrug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
Selling, Bernard
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
Shord, Stacy S.
- You have accessThe Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human HepatocytesCeleste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyseDrug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
Sinko, Patrick
- You have accessIntestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1Feng R. Luo, Pankaj V. Paranjpe, Ailan Guo, Eric Rubin and Patrick SinkoDrug Metabolism and Disposition July 2002, 30 (7) 763-770; DOI: https://doi.org/10.1124/dmd.30.7.763
Sinz, Michael
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
Snel, C. A. W.
- You have accessEvaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase InhibitorR. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. SnelDrug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
Stearns, Ralph A.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
Strauss, John R.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
Stresser, David M.
- You have accessCytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.David M. Stresser, Stephanie D. Turner, Andrew P. Blanchard, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition July 2002, 30 (7) 845-852; DOI: https://doi.org/10.1124/dmd.30.7.845
T
Tang, Frank S.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
Tang, Wei
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
Turner, Stephanie D.
- You have accessCytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.David M. Stresser, Stephanie D. Turner, Andrew P. Blanchard, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition July 2002, 30 (7) 845-852; DOI: https://doi.org/10.1124/dmd.30.7.845
V
Vanhoutte, E.
- You have accessEvaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase InhibitorR. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. SnelDrug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
W
Wang, Hongbing
- You have accessThe Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human HepatocytesCeleste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyseDrug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
Weber, Ann E.
- You have accessThe Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral BioavailabilityRalph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee ChiuDrug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
- You have accessMetabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid ConjugateWei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. BaillieDrug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
Whattam, M.
- You have accessEvaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase InhibitorR. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. SnelDrug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
Wong, Y. Nancy
- You have accessIn Vitro Interactions between a Potential Muscle Relaxant E2101 and Human Cytochromes P450Zhi-Yi Zhang, Belinda M. King, Nevena N. Mollova and Y. Nancy WongDrug Metabolism and Disposition July 2002, 30 (7) 805-813; DOI: https://doi.org/10.1124/dmd.30.7.805
X
Xie, Jindong
- You have accessCYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human HepatocytesGang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang GanDrug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
Y
Yan, Bingfang
- You have accessThe Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human HepatocytesCeleste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyseDrug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
Z
Zhang, Zhi-Yi
- You have accessIn Vitro Interactions between a Potential Muscle Relaxant E2101 and Human Cytochromes P450Zhi-Yi Zhang, Belinda M. King, Nevena N. Mollova and Y. Nancy WongDrug Metabolism and Disposition July 2002, 30 (7) 805-813; DOI: https://doi.org/10.1124/dmd.30.7.805