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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

July 01, 2002; Volume 30,Issue 7
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Arora, Vikram

    1. You have access
      Phosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug Metabolism
      Vikram Arora, Melissa L. Cate, Chandramallika Ghosh and Patrick L. Iversen
      Drug Metabolism and Disposition July 2002, 30 (7) 757-762; DOI: https://doi.org/10.1124/dmd.30.7.757

B

  1. Back, David J.

    1. You have access
      α1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral Regimens
      Marta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di Perri
      Drug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
  2. Baillie, Thomas A.

    1. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
  3. Blanchard, Andrew P.

    1. You have access
      Cytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.
      David M. Stresser, Stephanie D. Turner, Andrew P. Blanchard, Vaughn P. Miller and Charles L. Crespi
      Drug Metabolism and Disposition July 2002, 30 (7) 845-852; DOI: https://doi.org/10.1124/dmd.30.7.845
  4. Boffito, Marta

    1. You have access
      α1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral Regimens
      Marta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di Perri
      Drug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
  5. Bonora, Stefano

    1. You have access
      α1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral Regimens
      Marta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di Perri
      Drug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
  6. Boulieu, Roselyne

    1. You have access
      Contribution of CYP3A4, CYP2B6, and CYP2C9 Isoforms toN-Demethylation of Ketamine in Human Liver Microsomes
      Youssef Hijazi and Roselyne Boulieu
      Drug Metabolism and Disposition July 2002, 30 (7) 853-858; DOI: https://doi.org/10.1124/dmd.30.7.853
  7. Brady, James M.

    1. You have access
      Tissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in Rats
      James M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. Klaassen
      Drug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
  8. Buist, Susan C.

    1. You have access
      Tissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in Rats
      James M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. Klaassen
      Drug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
  9. Burn, Tim

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795

C

  1. Calam, A.

    1. You have access
      Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
      R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
      Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
  2. Carroll, Kathy

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
  3. Cate, Melissa L.

    1. You have access
      Phosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug Metabolism
      Vikram Arora, Melissa L. Cate, Chandramallika Ghosh and Patrick L. Iversen
      Drug Metabolism and Disposition July 2002, 30 (7) 757-762; DOI: https://doi.org/10.1124/dmd.30.7.757
  4. Cherrington, Nathan J.

    1. You have access
      Tissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in Rats
      James M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. Klaassen
      Drug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
  5. Chitty, Dawn

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
  6. Chiu, Shuet-Hing L.

    1. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
  7. Chiu, Shuet-Hing Lee

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
  8. Christ, Dave

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
  9. Colandrea, Vincent J.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
  10. Colletti, Adria E.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
  11. Crespi, Charles L.

    1. You have access
      Cytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.
      David M. Stresser, Stephanie D. Turner, Andrew P. Blanchard, Vaughn P. Miller and Charles L. Crespi
      Drug Metabolism and Disposition July 2002, 30 (7) 845-852; DOI: https://doi.org/10.1124/dmd.30.7.845
  12. Cunningham, Mark

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795

D

  1. Di Perri, Giovanni

    1. You have access
      α1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral Regimens
      Marta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di Perri
      Drug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
  2. Doss, George A.

    1. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
  3. Downey, April

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795

F

  1. Faucette, Stephanie

    1. You have access
      The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
      Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
      Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
  2. Feeney, William P.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771

G

  1. Gan, Liang-Shang

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
  2. Garner, J. V.

    1. You have access
      Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
      R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
      Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
  3. Garner, R. C.

    1. You have access
      Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
      R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
      Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
  4. Ghosh, Chandramallika

    1. You have access
      Phosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug Metabolism
      Vikram Arora, Melissa L. Cate, Chandramallika Ghosh and Patrick L. Iversen
      Drug Metabolism and Disposition July 2002, 30 (7) 757-762; DOI: https://doi.org/10.1124/dmd.30.7.757
  5. Gilbert, Darryl

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
    2. You have access
      The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
      Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
      Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
  6. Goris, I.

    1. You have access
      Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
      R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
      Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
  7. Graham, Richard

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
  8. Gregory, S.

    1. You have access
      Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
      R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
      Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
  9. Guo, Ailan

    1. You have access
      Intestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1
      Feng R. Luo, Pankaj V. Paranjpe, Ailan Guo, Eric Rubin and Patrick Sinko
      Drug Metabolism and Disposition July 2002, 30 (7) 763-770; DOI: https://doi.org/10.1124/dmd.30.7.763

H

  1. Hamilton, Geraldine

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
    2. You have access
      The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
      Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
      Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
  2. Hartley, Dylan P.

    1. You have access
      Tissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in Rats
      James M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. Klaassen
      Drug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
  3. Hawke, Roy L.

    1. You have access
      The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
      Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
      Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
  4. Hijazi, Youssef

    1. You have access
      Contribution of CYP3A4, CYP2B6, and CYP2C9 Isoforms toN-Demethylation of Ketamine in Human Liver Microsomes
      Youssef Hijazi and Roselyne Boulieu
      Drug Metabolism and Disposition July 2002, 30 (7) 853-858; DOI: https://doi.org/10.1124/dmd.30.7.853
  5. Hoggard, Patrick G.

    1. You have access
      α1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral Regimens
      Marta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di Perri
      Drug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859

I

  1. Iliff, Susan A.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
  2. Iversen, Patrick L.

    1. You have access
      Phosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug Metabolism
      Vikram Arora, Melissa L. Cate, Chandramallika Ghosh and Patrick L. Iversen
      Drug Metabolism and Disposition July 2002, 30 (7) 757-762; DOI: https://doi.org/10.1124/dmd.30.7.757

J

  1. Jolley, Summer

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
    2. You have access
      The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
      Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
      Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814

K

  1. Keohane, Carol A.

    1. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
  2. Keohane, Carol Ann

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
  3. Kim, Sean

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
  4. King, Belinda M.

    1. You have access
      In Vitro Interactions between a Potential Muscle Relaxant E2101 and Human Cytochromes P450
      Zhi-Yi Zhang, Belinda M. King, Nevena N. Mollova and Y. Nancy Wong
      Drug Metabolism and Disposition July 2002, 30 (7) 805-813; DOI: https://doi.org/10.1124/dmd.30.7.805
  5. Klaassen, Curtis D.

    1. You have access
      Tissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in Rats
      James M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. Klaassen
      Drug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
  6. Kwei, Gloria Y.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
    2. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778

L

  1. Laenen, A. A. E.

    1. You have access
      Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
      R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
      Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
  2. Lavigne, James A.

    1. You have access
      Identification of Human Hepatic Cytochrome P450 Sources of N-alkylprotoporphyrin IX after Interaction with Porphyrinogenic Xenobiotics, Implications for Detection of Xenobiotic-Induced Porphyria in Humans
      James A. Lavigne, Kanji Nakatsu and Gerald S. Marks
      Drug Metabolism and Disposition July 2002, 30 (7) 788-794; DOI: https://doi.org/10.1124/dmd.30.7.788
  3. LeCluyse, Edward

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
  4. LeCluyse, Edward L.

    1. You have access
      The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
      Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
      Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
  5. Leong, D.

    1. You have access
      Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
      R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
      Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
  6. Li, Ning

    1. You have access
      Tissue Distribution and Chemical Induction of Multiple Drug Resistance Genes in Rats
      James M. Brady, Nathan J. Cherrington, Dylan P. Hartley, Susan C. Buist, Ning Li and Curtis D. Klaassen
      Drug Metabolism and Disposition July 2002, 30 (7) 838-844; DOI: https://doi.org/10.1124/dmd.30.7.838
  7. Lin, Jianrong

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
  8. Lindley, Celeste

    1. You have access
      The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
      Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
      Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
  9. Luo, Feng R.

    1. You have access
      Intestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1
      Feng R. Luo, Pankaj V. Paranjpe, Ailan Guo, Eric Rubin and Patrick Sinko
      Drug Metabolism and Disposition July 2002, 30 (7) 763-770; DOI: https://doi.org/10.1124/dmd.30.7.763
  10. Luo, Gang

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795

M

  1. Madan, Ajay

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
  2. Marks, Gerald S.

    1. You have access
      Identification of Human Hepatic Cytochrome P450 Sources of N-alkylprotoporphyrin IX after Interaction with Porphyrinogenic Xenobiotics, Implications for Detection of Xenobiotic-Induced Porphyria in Humans
      James A. Lavigne, Kanji Nakatsu and Gerald S. Marks
      Drug Metabolism and Disposition July 2002, 30 (7) 788-794; DOI: https://doi.org/10.1124/dmd.30.7.788
  3. Mathvink, Robert J.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
    2. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
  4. McCune, Jeannine S.

    1. You have access
      The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
      Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
      Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
  5. Meuldermans, W.

    1. You have access
      Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
      R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
      Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
  6. Miller, Randall R.

    1. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
  7. Miller, Randy R.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
  8. Miller, Vaughn P.

    1. You have access
      Cytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.
      David M. Stresser, Stephanie D. Turner, Andrew P. Blanchard, Vaughn P. Miller and Charles L. Crespi
      Drug Metabolism and Disposition July 2002, 30 (7) 845-852; DOI: https://doi.org/10.1124/dmd.30.7.845
  9. Mollova, Nevena N.

    1. You have access
      In Vitro Interactions between a Potential Muscle Relaxant E2101 and Human Cytochromes P450
      Zhi-Yi Zhang, Belinda M. King, Nevena N. Mollova and Y. Nancy Wong
      Drug Metabolism and Disposition July 2002, 30 (7) 805-813; DOI: https://doi.org/10.1124/dmd.30.7.805
  10. Mudra, Daniel

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795

N

  1. Nakatsu, Kanji

    1. You have access
      Identification of Human Hepatic Cytochrome P450 Sources of N-alkylprotoporphyrin IX after Interaction with Porphyrinogenic Xenobiotics, Implications for Detection of Xenobiotic-Induced Porphyria in Humans
      James A. Lavigne, Kanji Nakatsu and Gerald S. Marks
      Drug Metabolism and Disposition July 2002, 30 (7) 788-794; DOI: https://doi.org/10.1124/dmd.30.7.788
  2. Naylor, Elizabeth M.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
  3. Ngui, Jason S.

    1. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778

O

  1. Obach, R. Scott

    1. You have access
      Measurement of Michaelis Constants for Cytochrome P450-Mediated Biotransformation Reactions Using a Substrate Depletion Approach
      R. Scott Obach and Anne E. Reed-Hagen
      Drug Metabolism and Disposition July 2002, 30 (7) 831-837; DOI: https://doi.org/10.1124/dmd.30.7.831

P

  1. Paranjpe, Pankaj V.

    1. You have access
      Intestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1
      Feng R. Luo, Pankaj V. Paranjpe, Ailan Guo, Eric Rubin and Patrick Sinko
      Drug Metabolism and Disposition July 2002, 30 (7) 763-770; DOI: https://doi.org/10.1124/dmd.30.7.763
  2. Parkinson, Andrew

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795

R

  1. Raiteri, Riccardo

    1. You have access
      α1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral Regimens
      Marta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di Perri
      Drug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
  2. Reed-Hagen, Anne E.

    1. You have access
      Measurement of Michaelis Constants for Cytochrome P450-Mediated Biotransformation Reactions Using a Substrate Depletion Approach
      R. Scott Obach and Anne E. Reed-Hagen
      Drug Metabolism and Disposition July 2002, 30 (7) 831-837; DOI: https://doi.org/10.1124/dmd.30.7.831
  3. Rizzo, Christopher

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
  4. Rubin, Eric

    1. You have access
      Intestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1
      Feng R. Luo, Pankaj V. Paranjpe, Ailan Guo, Eric Rubin and Patrick Sinko
      Drug Metabolism and Disposition July 2002, 30 (7) 763-770; DOI: https://doi.org/10.1124/dmd.30.7.763

S

  1. Sciolè, Katiusha

    1. You have access
      α1-Acid Glycoprotein Levels in Human Immunodeficiency Virus-Infected Subjects on Antiretroviral Regimens
      Marta Boffito, Katiusha Sciolè, Riccardo Raiteri, Stefano Bonora, Patrick G. Hoggard, David J. Back and Giovanni Di Perri
      Drug Metabolism and Disposition July 2002, 30 (7) 859-860; DOI: https://doi.org/10.1124/dmd.30.7.859
  2. Selling, Bernard

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
  3. Shord, Stacy S.

    1. You have access
      The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
      Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
      Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
  4. Sinko, Patrick

    1. You have access
      Intestinal Transport of Irinotecan in Caco-2 Cells and MDCK II Cells Overexpressing Efflux Transporters Pgp, cMOAT, and MRP1
      Feng R. Luo, Pankaj V. Paranjpe, Ailan Guo, Eric Rubin and Patrick Sinko
      Drug Metabolism and Disposition July 2002, 30 (7) 763-770; DOI: https://doi.org/10.1124/dmd.30.7.763
  5. Sinz, Michael

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795
  6. Snel, C. A. W.

    1. You have access
      Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
      R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
      Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
  7. Stearns, Ralph A.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
    2. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
  8. Strauss, John R.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
    2. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
  9. Stresser, David M.

    1. You have access
      Cytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.
      David M. Stresser, Stephanie D. Turner, Andrew P. Blanchard, Vaughn P. Miller and Charles L. Crespi
      Drug Metabolism and Disposition July 2002, 30 (7) 845-852; DOI: https://doi.org/10.1124/dmd.30.7.845

T

  1. Tang, Frank S.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
  2. Tang, Wei

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
    2. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
  3. Turner, Stephanie D.

    1. You have access
      Cytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.
      David M. Stresser, Stephanie D. Turner, Andrew P. Blanchard, Vaughn P. Miller and Charles L. Crespi
      Drug Metabolism and Disposition July 2002, 30 (7) 845-852; DOI: https://doi.org/10.1124/dmd.30.7.845

V

  1. Vanhoutte, E.

    1. You have access
      Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
      R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
      Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823

W

  1. Wang, Hongbing

    1. You have access
      The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
      Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
      Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814
  2. Weber, Ann E.

    1. You have access
      The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
      Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition July 2002, 30 (7) 771-777; DOI: https://doi.org/10.1124/dmd.30.7.771
    2. You have access
      Metabolism of a Thiazole Benzenesulfonamide Derivative, a Potent and Selective Agonist of the Human β3-Adrenergic Receptor, in Rats: Identification of a Novel Isethionic Acid Conjugate
      Wei Tang, Ralph A. Stearns, Randall R. Miller, Jason S. Ngui, Robert J. Mathvink, Ann E. Weber, Gloria Y. Kwei, John R. Strauss, Carol A. Keohane, George A. Doss, Shuet-Hing L. Chiu and Thomas A. Baillie
      Drug Metabolism and Disposition July 2002, 30 (7) 778-787; DOI: https://doi.org/10.1124/dmd.30.7.778
  3. Whattam, M.

    1. You have access
      Evaluation of Accelerator Mass Spectrometry in a Human Mass Balance and Pharmacokinetic Study–Experience with14C-labeled (R)-6-[Amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a Farnesyl Transferase Inhibitor
      R. C. Garner, I. Goris, A. A. E. Laenen, E. Vanhoutte, W. Meuldermans, S. Gregory, J. V. Garner, D. Leong, M. Whattam, A. Calam and C. A. W. Snel
      Drug Metabolism and Disposition July 2002, 30 (7) 823-830; DOI: https://doi.org/10.1124/dmd.30.7.823
  4. Wong, Y. Nancy

    1. You have access
      In Vitro Interactions between a Potential Muscle Relaxant E2101 and Human Cytochromes P450
      Zhi-Yi Zhang, Belinda M. King, Nevena N. Mollova and Y. Nancy Wong
      Drug Metabolism and Disposition July 2002, 30 (7) 805-813; DOI: https://doi.org/10.1124/dmd.30.7.805

X

  1. Xie, Jindong

    1. You have access
      CYP3A4 Induction by Drugs: Correlation between a Pregnane X Receptor Reporter Gene Assay and CYP3A4 Expression in Human Hepatocytes
      Gang Luo, Mark Cunningham, Sean Kim, Tim Burn, Jianrong Lin, Michael Sinz, Geraldine Hamilton, Christopher Rizzo, Summer Jolley, Darryl Gilbert, April Downey, Daniel Mudra, Richard Graham, Kathy Carroll, Jindong Xie, Ajay Madan, Andrew Parkinson, Dave Christ, Bernard Selling, Edward LeCluyse and Liang-Shang Gan
      Drug Metabolism and Disposition July 2002, 30 (7) 795-804; DOI: https://doi.org/10.1124/dmd.30.7.795

Y

  1. Yan, Bingfang

    1. You have access
      The Effect of Cyclophosphamide with and without Dexamethasone on Cytochrome P450 3A4 and 2B6 in Human Hepatocytes
      Celeste Lindley, Geraldine Hamilton, Jeannine S. McCune, Stephanie Faucette, Stacy S. Shord, Roy L. Hawke, Hongbing Wang, Darryl Gilbert, Summer Jolley, Bingfang Yan and Edward L. LeCluyse
      Drug Metabolism and Disposition July 2002, 30 (7) 814-822; DOI: https://doi.org/10.1124/dmd.30.7.814

Z

  1. Zhang, Zhi-Yi

    1. You have access
      In Vitro Interactions between a Potential Muscle Relaxant E2101 and Human Cytochromes P450
      Zhi-Yi Zhang, Belinda M. King, Nevena N. Mollova and Y. Nancy Wong
      Drug Metabolism and Disposition July 2002, 30 (7) 805-813; DOI: https://doi.org/10.1124/dmd.30.7.805
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Drug Metabolism and Disposition: 30 (7)
Drug Metabolism and Disposition
Vol. 30, Issue 7
1 Jul 2002
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
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