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Index by author

August 01, 2002; Volume 30,Issue 8

A

  1. Augustijns, P.

    1. Intestinal Absorption Enhancement of the Ester Prodrug Tenofovir Disoproxil Fumarate through Modulation of the Biochemical Barrier by Defined Ester Mixtures
      J. van Gelder, S. Deferme, L. Naesens, E. De Clercq, G. van den Mooter, R. Kinget and P. Augustijns
      Drug Metabolism and Disposition August 2002, 30 (8) 924-930; DOI: https://doi.org/10.1124/dmd.30.8.924

B

  1. Brouwer, Kim L. R.

    1. Role of Constitutive Androstane Receptor in the In Vivo Induction of Mrp3 and CYP2B1/2 by Phenobarbital
      Hao Xiong, Kouichi Yoshinari, Kim L. R. Brouwer and Masahiko Negishi
      Drug Metabolism and Disposition August 2002, 30 (8) 918-923; DOI: https://doi.org/10.1124/dmd.30.8.918

C

  1. Cantrell, Varon E.

    1. Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7
      J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James Eckstein, Kenneth Ruterbories, Mitchell A. Hamman, Stephen D. Hall and Steven A. Wrighton
      Drug Metabolism and Disposition August 2002, 30 (8) 883-891; DOI: https://doi.org/10.1124/dmd.30.8.883

  2. Chanas, Brian

    1. Cytochrome P450 2E1 (CYP2E1) is Essential for Acrylonitrile Metabolism to Cyanide: Comparative Studies Using CYP2E1-Null and Wild-Type Mice
      Hongbing Wang, Brian Chanas and Burhan I. Ghanayem
      Drug Metabolism and Disposition August 2002, 30 (8) 911-917; DOI: https://doi.org/10.1124/dmd.30.8.911

  3. Chiba, Masato

    1. Prediction of Hepatic Clearance and Availability by Cryopreserved Human Hepatocytes: An Application of Serum Incubation Method
      Yoshihiro Shibata, Hiroyuki Takahashi, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition August 2002, 30 (8) 892-896; DOI: https://doi.org/10.1124/dmd.30.8.892

  4. Chiu, Shuet-Hing L.

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

  5. Crewe, H. Kim

    1. Metabolism of Tamoxifen by Recombinant Human Cytochrome P450 Enzymes: Formation of the 4-Hydroxy, 4′-Hydroxy andN-Desmethyl Metabolites and Isomerization oftrans-4-Hydroxytamoxifen
      H. Kim Crewe, Lisa M. Notley, Rebecca M. Wunsch, Martin S. Lennard and Elizabeth M. J. Gillam
      Drug Metabolism and Disposition August 2002, 30 (8) 869-874; DOI: https://doi.org/10.1124/dmd.30.8.869

  6. Curtis, Neil

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

D

  1. Dabrowiak, James C.

    1. Kinetic Analysis of the Reactions of 4-Hydroperoxycyclophosphamide and Acrolein With Glutathione, Mesna, and Wr-1065
      Kirk A. Tacka, James C. Dabrowiak, Jerry Goodisman and Abdul-Kader Souid
      Drug Metabolism and Disposition August 2002, 30 (8) 875-882; DOI: https://doi.org/10.1124/dmd.30.8.875

  2. Dean, Dennis C.

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

  3. De Clercq, E.

    1. Intestinal Absorption Enhancement of the Ester Prodrug Tenofovir Disoproxil Fumarate through Modulation of the Biochemical Barrier by Defined Ester Mixtures
      J. van Gelder, S. Deferme, L. Naesens, E. De Clercq, G. van den Mooter, R. Kinget and P. Augustijns
      Drug Metabolism and Disposition August 2002, 30 (8) 924-930; DOI: https://doi.org/10.1124/dmd.30.8.924

  4. Deferme, S.

    1. Intestinal Absorption Enhancement of the Ester Prodrug Tenofovir Disoproxil Fumarate through Modulation of the Biochemical Barrier by Defined Ester Mixtures
      J. van Gelder, S. Deferme, L. Naesens, E. De Clercq, G. van den Mooter, R. Kinget and P. Augustijns
      Drug Metabolism and Disposition August 2002, 30 (8) 924-930; DOI: https://doi.org/10.1124/dmd.30.8.924

E

  1. Eckstein, James

    1. Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7
      J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James Eckstein, Kenneth Ruterbories, Mitchell A. Hamman, Stephen D. Hall and Steven A. Wrighton
      Drug Metabolism and Disposition August 2002, 30 (8) 883-891; DOI: https://doi.org/10.1124/dmd.30.8.883

  2. Elipe, Maria Victoria Silva

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

  3. Elliott, Jason

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

  4. Evans, David C.

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

F

  1. Friedman, Michael

    1. Pharmacokinetic-Pharmacodynamic Analysis of the Glucose-Lowering Effect of Metformin in Diabetic Rats Reveals First-Pass Pharmacodynamic Effect
      David Stepensky, Michael Friedman, Itamar Raz and Amnon Hoffman
      Drug Metabolism and Disposition August 2002, 30 (8) 861-868; DOI: https://doi.org/10.1124/dmd.30.8.861

G

  1. Gerhard, Ute

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

  2. Ghanayem, Burhan I.

    1. Cytochrome P450 2E1 (CYP2E1) is Essential for Acrylonitrile Metabolism to Cyanide: Comparative Studies Using CYP2E1-Null and Wild-Type Mice
      Hongbing Wang, Brian Chanas and Burhan I. Ghanayem
      Drug Metabolism and Disposition August 2002, 30 (8) 911-917; DOI: https://doi.org/10.1124/dmd.30.8.911

  3. Gillam, Elizabeth M. J.

    1. Metabolism of Tamoxifen by Recombinant Human Cytochrome P450 Enzymes: Formation of the 4-Hydroxy, 4′-Hydroxy andN-Desmethyl Metabolites and Isomerization oftrans-4-Hydroxytamoxifen
      H. Kim Crewe, Lisa M. Notley, Rebecca M. Wunsch, Martin S. Lennard and Elizabeth M. J. Gillam
      Drug Metabolism and Disposition August 2002, 30 (8) 869-874; DOI: https://doi.org/10.1124/dmd.30.8.869

  4. Goodisman, Jerry

    1. Kinetic Analysis of the Reactions of 4-Hydroperoxycyclophosphamide and Acrolein With Glutathione, Mesna, and Wr-1065
      Kirk A. Tacka, James C. Dabrowiak, Jerry Goodisman and Abdul-Kader Souid
      Drug Metabolism and Disposition August 2002, 30 (8) 875-882; DOI: https://doi.org/10.1124/dmd.30.8.875

H

  1. Hall, Stephen D.

    1. Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7
      J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James Eckstein, Kenneth Ruterbories, Mitchell A. Hamman, Stephen D. Hall and Steven A. Wrighton
      Drug Metabolism and Disposition August 2002, 30 (8) 883-891; DOI: https://doi.org/10.1124/dmd.30.8.883

  2. Hamman, Mitchell A.

    1. Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7
      J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James Eckstein, Kenneth Ruterbories, Mitchell A. Hamman, Stephen D. Hall and Steven A. Wrighton
      Drug Metabolism and Disposition August 2002, 30 (8) 883-891; DOI: https://doi.org/10.1124/dmd.30.8.883

  3. Hoffman, Amnon

    1. Pharmacokinetic-Pharmacodynamic Analysis of the Glucose-Lowering Effect of Metformin in Diabetic Rats Reveals First-Pass Pharmacodynamic Effect
      David Stepensky, Michael Friedman, Itamar Raz and Amnon Hoffman
      Drug Metabolism and Disposition August 2002, 30 (8) 861-868; DOI: https://doi.org/10.1124/dmd.30.8.861

  4. Honma, Wataru

    1. Phenol Sulfotransferase, ST1A3, as the Main Enzyme Catalyzing Sulfation of Troglitazone in Human Liver
      Wataru Honma, Miki Shimada, Hironobu Sasano, Shogo Ozawa, Masaaki Miyata, Kiyoshi Nagata, Toshihiko Ikeda and Yasushi Yamazoe
      Drug Metabolism and Disposition August 2002, 30 (8) 944-949; DOI: https://doi.org/10.1124/dmd.30.8.944

  5. Hop, Cornelis E. C. A.

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

I

  1. Ikeda, Toshihiko

    1. Sex Difference in Inhibition of In Vitro Mexazolam Metabolism by Various 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors in Rat Liver Microsomes
      Michi Ishigami, Wataru Takasaki, Toshihiko Ikeda, Toru Komai, Kiyomi Ito and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2002, 30 (8) 904-910; DOI: https://doi.org/10.1124/dmd.30.8.904
    2. Phenol Sulfotransferase, ST1A3, as the Main Enzyme Catalyzing Sulfation of Troglitazone in Human Liver
      Wataru Honma, Miki Shimada, Hironobu Sasano, Shogo Ozawa, Masaaki Miyata, Kiyoshi Nagata, Toshihiko Ikeda and Yasushi Yamazoe
      Drug Metabolism and Disposition August 2002, 30 (8) 944-949; DOI: https://doi.org/10.1124/dmd.30.8.944

  2. Ishibashi, Fumihide

    1. Amino Acid Residues Affecting the Activities of Human Cytochrome P450 2C9 and 2C19
      Toshiro Niwa, Akira Kageyama, Kae Kishimoto, Yoshiyasu Yabusaki, Fumihide Ishibashi and Masanao Katagiri
      Drug Metabolism and Disposition August 2002, 30 (8) 931-936; DOI: https://doi.org/10.1124/dmd.30.8.931

  3. Ishigami, Michi

    1. Sex Difference in Inhibition of In Vitro Mexazolam Metabolism by Various 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors in Rat Liver Microsomes
      Michi Ishigami, Wataru Takasaki, Toshihiko Ikeda, Toru Komai, Kiyomi Ito and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2002, 30 (8) 904-910; DOI: https://doi.org/10.1124/dmd.30.8.904

  4. Ishii, Yasuyuki

    1. Prediction of Hepatic Clearance and Availability by Cryopreserved Human Hepatocytes: An Application of Serum Incubation Method
      Yoshihiro Shibata, Hiroyuki Takahashi, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition August 2002, 30 (8) 892-896; DOI: https://doi.org/10.1124/dmd.30.8.892

  5. Ito, Kiyomi

    1. Sex Difference in Inhibition of In Vitro Mexazolam Metabolism by Various 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors in Rat Liver Microsomes
      Michi Ishigami, Wataru Takasaki, Toshihiko Ikeda, Toru Komai, Kiyomi Ito and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2002, 30 (8) 904-910; DOI: https://doi.org/10.1124/dmd.30.8.904

J

  1. Jones, David R.

    1. Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7
      J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James Eckstein, Kenneth Ruterbories, Mitchell A. Hamman, Stephen D. Hall and Steven A. Wrighton
      Drug Metabolism and Disposition August 2002, 30 (8) 883-891; DOI: https://doi.org/10.1124/dmd.30.8.883

K

  1. Kageyama, Akira

    1. Amino Acid Residues Affecting the Activities of Human Cytochrome P450 2C9 and 2C19
      Toshiro Niwa, Akira Kageyama, Kae Kishimoto, Yoshiyasu Yabusaki, Fumihide Ishibashi and Masanao Katagiri
      Drug Metabolism and Disposition August 2002, 30 (8) 931-936; DOI: https://doi.org/10.1124/dmd.30.8.931

  2. Katagiri, Masanao

    1. Amino Acid Residues Affecting the Activities of Human Cytochrome P450 2C9 and 2C19
      Toshiro Niwa, Akira Kageyama, Kae Kishimoto, Yoshiyasu Yabusaki, Fumihide Ishibashi and Masanao Katagiri
      Drug Metabolism and Disposition August 2002, 30 (8) 931-936; DOI: https://doi.org/10.1124/dmd.30.8.931

  3. Keohane, Carol-Ann

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

  4. Kinget, R.

    1. Intestinal Absorption Enhancement of the Ester Prodrug Tenofovir Disoproxil Fumarate through Modulation of the Biochemical Barrier by Defined Ester Mixtures
      J. van Gelder, S. Deferme, L. Naesens, E. De Clercq, G. van den Mooter, R. Kinget and P. Augustijns
      Drug Metabolism and Disposition August 2002, 30 (8) 924-930; DOI: https://doi.org/10.1124/dmd.30.8.924

  5. Kishimoto, Kae

    1. Amino Acid Residues Affecting the Activities of Human Cytochrome P450 2C9 and 2C19
      Toshiro Niwa, Akira Kageyama, Kae Kishimoto, Yoshiyasu Yabusaki, Fumihide Ishibashi and Masanao Katagiri
      Drug Metabolism and Disposition August 2002, 30 (8) 931-936; DOI: https://doi.org/10.1124/dmd.30.8.931

  6. Komai, Toru

    1. Sex Difference in Inhibition of In Vitro Mexazolam Metabolism by Various 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors in Rat Liver Microsomes
      Michi Ishigami, Wataru Takasaki, Toshihiko Ikeda, Toru Komai, Kiyomi Ito and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2002, 30 (8) 904-910; DOI: https://doi.org/10.1124/dmd.30.8.904

  7. Kumar, Sanjeev

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

L

  1. Lennard, Martin S.

    1. Metabolism of Tamoxifen by Recombinant Human Cytochrome P450 Enzymes: Formation of the 4-Hydroxy, 4′-Hydroxy andN-Desmethyl Metabolites and Isomerization oftrans-4-Hydroxytamoxifen
      H. Kim Crewe, Lisa M. Notley, Rebecca M. Wunsch, Martin S. Lennard and Elizabeth M. J. Gillam
      Drug Metabolism and Disposition August 2002, 30 (8) 869-874; DOI: https://doi.org/10.1124/dmd.30.8.869

  2. Locker, Karen

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

M

  1. Miyata, Masaaki

    1. Phenol Sulfotransferase, ST1A3, as the Main Enzyme Catalyzing Sulfation of Troglitazone in Human Liver
      Wataru Honma, Miki Shimada, Hironobu Sasano, Shogo Ozawa, Masaaki Miyata, Kiyoshi Nagata, Toshihiko Ikeda and Yasushi Yamazoe
      Drug Metabolism and Disposition August 2002, 30 (8) 944-949; DOI: https://doi.org/10.1124/dmd.30.8.944

  2. Morrison, Denise

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

  3. Mortishire-Smith, Russell

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

N

  1. Naesens, L.

    1. Intestinal Absorption Enhancement of the Ester Prodrug Tenofovir Disoproxil Fumarate through Modulation of the Biochemical Barrier by Defined Ester Mixtures
      J. van Gelder, S. Deferme, L. Naesens, E. De Clercq, G. van den Mooter, R. Kinget and P. Augustijns
      Drug Metabolism and Disposition August 2002, 30 (8) 924-930; DOI: https://doi.org/10.1124/dmd.30.8.924

  2. Nagata, Kiyoshi

    1. Phenol Sulfotransferase, ST1A3, as the Main Enzyme Catalyzing Sulfation of Troglitazone in Human Liver
      Wataru Honma, Miki Shimada, Hironobu Sasano, Shogo Ozawa, Masaaki Miyata, Kiyoshi Nagata, Toshihiko Ikeda and Yasushi Yamazoe
      Drug Metabolism and Disposition August 2002, 30 (8) 944-949; DOI: https://doi.org/10.1124/dmd.30.8.944

  3. Negishi, Masahiko

    1. Role of Constitutive Androstane Receptor in the In Vivo Induction of Mrp3 and CYP2B1/2 by Phenobarbital
      Hao Xiong, Kouichi Yoshinari, Kim L. R. Brouwer and Masahiko Negishi
      Drug Metabolism and Disposition August 2002, 30 (8) 918-923; DOI: https://doi.org/10.1124/dmd.30.8.918

  4. Niwa, Toshiro

    1. Amino Acid Residues Affecting the Activities of Human Cytochrome P450 2C9 and 2C19
      Toshiro Niwa, Akira Kageyama, Kae Kishimoto, Yoshiyasu Yabusaki, Fumihide Ishibashi and Masanao Katagiri
      Drug Metabolism and Disposition August 2002, 30 (8) 931-936; DOI: https://doi.org/10.1124/dmd.30.8.931

  5. Notley, Lisa M.

    1. Metabolism of Tamoxifen by Recombinant Human Cytochrome P450 Enzymes: Formation of the 4-Hydroxy, 4′-Hydroxy andN-Desmethyl Metabolites and Isomerization oftrans-4-Hydroxytamoxifen
      H. Kim Crewe, Lisa M. Notley, Rebecca M. Wunsch, Martin S. Lennard and Elizabeth M. J. Gillam
      Drug Metabolism and Disposition August 2002, 30 (8) 869-874; DOI: https://doi.org/10.1124/dmd.30.8.869

O

  1. Ozawa, Shogo

    1. Phenol Sulfotransferase, ST1A3, as the Main Enzyme Catalyzing Sulfation of Troglitazone in Human Liver
      Wataru Honma, Miki Shimada, Hironobu Sasano, Shogo Ozawa, Masaaki Miyata, Kiyoshi Nagata, Toshihiko Ikeda and Yasushi Yamazoe
      Drug Metabolism and Disposition August 2002, 30 (8) 944-949; DOI: https://doi.org/10.1124/dmd.30.8.944

P

  1. Poon, Grace K.

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

R

  1. Raab, Conrad E.

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

  2. Raz, Itamar

    1. Pharmacokinetic-Pharmacodynamic Analysis of the Glucose-Lowering Effect of Metformin in Diabetic Rats Reveals First-Pass Pharmacodynamic Effect
      David Stepensky, Michael Friedman, Itamar Raz and Amnon Hoffman
      Drug Metabolism and Disposition August 2002, 30 (8) 861-868; DOI: https://doi.org/10.1124/dmd.30.8.861

  3. Ring, Barbara J.

    1. Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7
      J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James Eckstein, Kenneth Ruterbories, Mitchell A. Hamman, Stephen D. Hall and Steven A. Wrighton
      Drug Metabolism and Disposition August 2002, 30 (8) 883-891; DOI: https://doi.org/10.1124/dmd.30.8.883

  4. Ruterbories, Kenneth

    1. Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7
      J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James Eckstein, Kenneth Ruterbories, Mitchell A. Hamman, Stephen D. Hall and Steven A. Wrighton
      Drug Metabolism and Disposition August 2002, 30 (8) 883-891; DOI: https://doi.org/10.1124/dmd.30.8.883

S

  1. Sasano, Hironobu

    1. Phenol Sulfotransferase, ST1A3, as the Main Enzyme Catalyzing Sulfation of Troglitazone in Human Liver
      Wataru Honma, Miki Shimada, Hironobu Sasano, Shogo Ozawa, Masaaki Miyata, Kiyoshi Nagata, Toshihiko Ikeda and Yasushi Yamazoe
      Drug Metabolism and Disposition August 2002, 30 (8) 944-949; DOI: https://doi.org/10.1124/dmd.30.8.944

  2. Shibata, Yoshihiro

    1. Prediction of Hepatic Clearance and Availability by Cryopreserved Human Hepatocytes: An Application of Serum Incubation Method
      Yoshihiro Shibata, Hiroyuki Takahashi, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition August 2002, 30 (8) 892-896; DOI: https://doi.org/10.1124/dmd.30.8.892

  3. Shimada, Miki

    1. Phenol Sulfotransferase, ST1A3, as the Main Enzyme Catalyzing Sulfation of Troglitazone in Human Liver
      Wataru Honma, Miki Shimada, Hironobu Sasano, Shogo Ozawa, Masaaki Miyata, Kiyoshi Nagata, Toshihiko Ikeda and Yasushi Yamazoe
      Drug Metabolism and Disposition August 2002, 30 (8) 944-949; DOI: https://doi.org/10.1124/dmd.30.8.944

  4. Souid, Abdul-Kader

    1. Kinetic Analysis of the Reactions of 4-Hydroperoxycyclophosphamide and Acrolein With Glutathione, Mesna, and Wr-1065
      Kirk A. Tacka, James C. Dabrowiak, Jerry Goodisman and Abdul-Kader Souid
      Drug Metabolism and Disposition August 2002, 30 (8) 875-882; DOI: https://doi.org/10.1124/dmd.30.8.875

  5. Stepensky, David

    1. Pharmacokinetic-Pharmacodynamic Analysis of the Glucose-Lowering Effect of Metformin in Diabetic Rats Reveals First-Pass Pharmacodynamic Effect
      David Stepensky, Michael Friedman, Itamar Raz and Amnon Hoffman
      Drug Metabolism and Disposition August 2002, 30 (8) 861-868; DOI: https://doi.org/10.1124/dmd.30.8.861

  6. Strauss, John

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

  7. Sugiyama, Yuichi

    1. Sex Difference in Inhibition of In Vitro Mexazolam Metabolism by Various 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors in Rat Liver Microsomes
      Michi Ishigami, Wataru Takasaki, Toshihiko Ikeda, Toru Komai, Kiyomi Ito and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2002, 30 (8) 904-910; DOI: https://doi.org/10.1124/dmd.30.8.904

T

  1. Tacka, Kirk A.

    1. Kinetic Analysis of the Reactions of 4-Hydroperoxycyclophosphamide and Acrolein With Glutathione, Mesna, and Wr-1065
      Kirk A. Tacka, James C. Dabrowiak, Jerry Goodisman and Abdul-Kader Souid
      Drug Metabolism and Disposition August 2002, 30 (8) 875-882; DOI: https://doi.org/10.1124/dmd.30.8.875

  2. Takahashi, Hiroyuki

    1. Prediction of Hepatic Clearance and Availability by Cryopreserved Human Hepatocytes: An Application of Serum Incubation Method
      Yoshihiro Shibata, Hiroyuki Takahashi, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition August 2002, 30 (8) 892-896; DOI: https://doi.org/10.1124/dmd.30.8.892

  3. Takasaki, Wataru

    1. Sex Difference in Inhibition of In Vitro Mexazolam Metabolism by Various 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors in Rat Liver Microsomes
      Michi Ishigami, Wataru Takasaki, Toshihiko Ikeda, Toru Komai, Kiyomi Ito and Yuichi Sugiyama
      Drug Metabolism and Disposition August 2002, 30 (8) 904-910; DOI: https://doi.org/10.1124/dmd.30.8.904

  4. Thomas, Steven

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

V

  1. Vaidyanathan, Jaya Bharathi

    1. Glucuronidation and Sulfation of the Tea Flavonoid (−)-Epicatechin by the Human and Rat Enzymes
      Jaya Bharathi Vaidyanathan and Thomas Walle
      Drug Metabolism and Disposition August 2002, 30 (8) 897-903; DOI: https://doi.org/10.1124/dmd.30.8.897

  2. van den Mooter, G.

    1. Intestinal Absorption Enhancement of the Ester Prodrug Tenofovir Disoproxil Fumarate through Modulation of the Biochemical Barrier by Defined Ester Mixtures
      J. van Gelder, S. Deferme, L. Naesens, E. De Clercq, G. van den Mooter, R. Kinget and P. Augustijns
      Drug Metabolism and Disposition August 2002, 30 (8) 924-930; DOI: https://doi.org/10.1124/dmd.30.8.924

  3. van Gelder, J.

    1. Intestinal Absorption Enhancement of the Ester Prodrug Tenofovir Disoproxil Fumarate through Modulation of the Biochemical Barrier by Defined Ester Mixtures
      J. van Gelder, S. Deferme, L. Naesens, E. De Clercq, G. van den Mooter, R. Kinget and P. Augustijns
      Drug Metabolism and Disposition August 2002, 30 (8) 924-930; DOI: https://doi.org/10.1124/dmd.30.8.924

W

  1. Walle, Thomas

    1. Glucuronidation and Sulfation of the Tea Flavonoid (−)-Epicatechin by the Human and Rat Enzymes
      Jaya Bharathi Vaidyanathan and Thomas Walle
      Drug Metabolism and Disposition August 2002, 30 (8) 897-903; DOI: https://doi.org/10.1124/dmd.30.8.897

  2. Wang, Hongbing

    1. Cytochrome P450 2E1 (CYP2E1) is Essential for Acrylonitrile Metabolism to Cyanide: Comparative Studies Using CYP2E1-Null and Wild-Type Mice
      Hongbing Wang, Brian Chanas and Burhan I. Ghanayem
      Drug Metabolism and Disposition August 2002, 30 (8) 911-917; DOI: https://doi.org/10.1124/dmd.30.8.911

  3. Wang, Yanfeng

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

  4. Watt, Alan P.

    1. Identification of Metabolites of a Substance P (Neurokinin 1 Receptor) Antagonist in Rat Hepatocytes and Rat Plasma
      Cornelis E. C. A. Hop, Yanfeng Wang, Sanjeev Kumar, Maria Victoria Silva Elipe, Conrad E. Raab, Dennis C. Dean, Grace K. Poon, Carol-Ann Keohane, John Strauss, Shuet-Hing L. Chiu, Neil Curtis, Jason Elliott, Ute Gerhard, Karen Locker, Denise Morrison, Russell Mortishire-Smith, Steven Thomas, Alan P. Watt and David C. Evans
      Drug Metabolism and Disposition August 2002, 30 (8) 937-943; DOI: https://doi.org/10.1124/dmd.30.8.937

  5. Williams, J. Andrew

    1. Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7
      J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James Eckstein, Kenneth Ruterbories, Mitchell A. Hamman, Stephen D. Hall and Steven A. Wrighton
      Drug Metabolism and Disposition August 2002, 30 (8) 883-891; DOI: https://doi.org/10.1124/dmd.30.8.883

  6. Wrighton, Steven A.

    1. Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7
      J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James Eckstein, Kenneth Ruterbories, Mitchell A. Hamman, Stephen D. Hall and Steven A. Wrighton
      Drug Metabolism and Disposition August 2002, 30 (8) 883-891; DOI: https://doi.org/10.1124/dmd.30.8.883

  7. Wunsch, Rebecca M.

    1. Metabolism of Tamoxifen by Recombinant Human Cytochrome P450 Enzymes: Formation of the 4-Hydroxy, 4′-Hydroxy andN-Desmethyl Metabolites and Isomerization oftrans-4-Hydroxytamoxifen
      H. Kim Crewe, Lisa M. Notley, Rebecca M. Wunsch, Martin S. Lennard and Elizabeth M. J. Gillam
      Drug Metabolism and Disposition August 2002, 30 (8) 869-874; DOI: https://doi.org/10.1124/dmd.30.8.869

X

  1. Xiong, Hao

    1. Role of Constitutive Androstane Receptor in the In Vivo Induction of Mrp3 and CYP2B1/2 by Phenobarbital
      Hao Xiong, Kouichi Yoshinari, Kim L. R. Brouwer and Masahiko Negishi
      Drug Metabolism and Disposition August 2002, 30 (8) 918-923; DOI: https://doi.org/10.1124/dmd.30.8.918

Y

  1. Yabusaki, Yoshiyasu

    1. Amino Acid Residues Affecting the Activities of Human Cytochrome P450 2C9 and 2C19
      Toshiro Niwa, Akira Kageyama, Kae Kishimoto, Yoshiyasu Yabusaki, Fumihide Ishibashi and Masanao Katagiri
      Drug Metabolism and Disposition August 2002, 30 (8) 931-936; DOI: https://doi.org/10.1124/dmd.30.8.931

  2. Yamazoe, Yasushi

    1. Phenol Sulfotransferase, ST1A3, as the Main Enzyme Catalyzing Sulfation of Troglitazone in Human Liver
      Wataru Honma, Miki Shimada, Hironobu Sasano, Shogo Ozawa, Masaaki Miyata, Kiyoshi Nagata, Toshihiko Ikeda and Yasushi Yamazoe
      Drug Metabolism and Disposition August 2002, 30 (8) 944-949; DOI: https://doi.org/10.1124/dmd.30.8.944

  3. Yoshinari, Kouichi

    1. Role of Constitutive Androstane Receptor in the In Vivo Induction of Mrp3 and CYP2B1/2 by Phenobarbital
      Hao Xiong, Kouichi Yoshinari, Kim L. R. Brouwer and Masahiko Negishi
      Drug Metabolism and Disposition August 2002, 30 (8) 918-923; DOI: https://doi.org/10.1124/dmd.30.8.918
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