Index by author
January 01, 2003; Volume 31,Issue 1
A
Abbott, F. S.
- You have accessAmino Acid Conjugates: Metabolites of 2-Propylpentanoic Acid (Valproic Acid) in Epileptic PatientsV. S. Gopaul, W. Tang, K. Farrell and F. S. AbbottDrug Metabolism and Disposition January 2003, 31 (1) 114-121; DOI: https://doi.org/10.1124/dmd.31.1.114
Ando, Masanori
- You have accessGlucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486DHideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi SawadaDrug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108
B
Bandiera, Stelvio M.
- You have accessConstitutive Androstane Receptor and Pregnane X Receptor Gene Expression in Human Liver: Interindividual Variability and Correlation with CYP2B6 mRNA LevelsThomas K. H. Chang, Stelvio M. Bandiera and Jie ChenDrug Metabolism and Disposition January 2003, 31 (1) 7-10; DOI: https://doi.org/10.1124/dmd.31.1.7
Barbuch, Robert J.
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle DogEdward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael SauerDrug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
Baxter, James
- You have accessMetabolism, Pharmacokinetics, and Excretion of a Highly SelectiveN-Methyl-d-aspartate Receptor Antagonist, Traxoprodil, in Human Cytochrome P450 2D6 Extensive and Poor MetabolizersKim Johnson, Ajit Shah, Sarah Jaw-Tsai, James Baxter and Chandra PrakashDrug Metabolism and Disposition January 2003, 31 (1) 76-87; DOI: https://doi.org/10.1124/dmd.31.1.76
Bonacorsi, Samuel
- You have accessComparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and HumansRamaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin KripalaniDrug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67
C
Chang, Thomas K. H.
- You have accessConstitutive Androstane Receptor and Pregnane X Receptor Gene Expression in Human Liver: Interindividual Variability and Correlation with CYP2B6 mRNA LevelsThomas K. H. Chang, Stelvio M. Bandiera and Jie ChenDrug Metabolism and Disposition January 2003, 31 (1) 7-10; DOI: https://doi.org/10.1124/dmd.31.1.7
Chen, Hao
- You have accessMetabolism of (S)-5,6-Difluoro-4-cyclopropylethynyl-4-trifluoromethyl-3, 4-dihydro-2(1H)-quinazolinone, a Non-Nucleoside Reverse Transcriptase Inhibitor, in Human Liver Microsomes. Metabolic Activation and Enzyme KineticsHao Chen, Weiqi Chen, Liang-Shang Gan and Abdul E. MutlibDrug Metabolism and Disposition January 2003, 31 (1) 122-132; DOI: https://doi.org/10.1124/dmd.31.1.122
Chen, Jie
- You have accessConstitutive Androstane Receptor and Pregnane X Receptor Gene Expression in Human Liver: Interindividual Variability and Correlation with CYP2B6 mRNA LevelsThomas K. H. Chang, Stelvio M. Bandiera and Jie ChenDrug Metabolism and Disposition January 2003, 31 (1) 7-10; DOI: https://doi.org/10.1124/dmd.31.1.7
Chen, Weiqi
- You have accessMetabolism of (S)-5,6-Difluoro-4-cyclopropylethynyl-4-trifluoromethyl-3, 4-dihydro-2(1H)-quinazolinone, a Non-Nucleoside Reverse Transcriptase Inhibitor, in Human Liver Microsomes. Metabolic Activation and Enzyme KineticsHao Chen, Weiqi Chen, Liang-Shang Gan and Abdul E. MutlibDrug Metabolism and Disposition January 2003, 31 (1) 122-132; DOI: https://doi.org/10.1124/dmd.31.1.122
Clarke, Thomas A.
- You have accessThe Metabolism of Clopidogrel Is Catalyzed by Human Cytochrome P450 3A and Is Inhibited by AtorvastatinThomas A. Clarke and Lucy A. WaskellDrug Metabolism and Disposition January 2003, 31 (1) 53-59; DOI: https://doi.org/10.1124/dmd.31.1.53
Cole, Susan P. C.
- You have accessBioflavonoid Stimulation of Glutathione Transport by the 190-kDa Multidrug Resistance Protein 1 (MRP1)Elaine M. Leslie, Roger G. Deeley and Susan P. C. ColeDrug Metabolism and Disposition January 2003, 31 (1) 11-15; DOI: https://doi.org/10.1124/dmd.31.1.11
Conrad, Preston C.
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle DogEdward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael SauerDrug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
Court, Michael H.
- You have accessValidation of Serotonin (5-Hydroxtryptamine) as an in Vitro Substrate Probe for Human UDP-Glucuronosyltransferase (UGT) 1A6Soundararajan Krishnaswamy, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt and Michael H. CourtDrug Metabolism and Disposition January 2003, 31 (1) 133-139; DOI: https://doi.org/10.1124/dmd.31.1.133
D
Deeley, Roger G.
- You have accessBioflavonoid Stimulation of Glutathione Transport by the 190-kDa Multidrug Resistance Protein 1 (MRP1)Elaine M. Leslie, Roger G. Deeley and Susan P. C. ColeDrug Metabolism and Disposition January 2003, 31 (1) 11-15; DOI: https://doi.org/10.1124/dmd.31.1.11
Desante, Karl A.
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and MetabolismJohn-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. DesanteDrug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98
Duan, Su X.
- You have accessValidation of Serotonin (5-Hydroxtryptamine) as an in Vitro Substrate Probe for Human UDP-Glucuronosyltransferase (UGT) 1A6Soundararajan Krishnaswamy, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt and Michael H. CourtDrug Metabolism and Disposition January 2003, 31 (1) 133-139; DOI: https://doi.org/10.1124/dmd.31.1.133
F
Fan, Peter W.
- You have accessMechanism-Based Inactivation of Cytochrome P450 2B6 by a Novel Terminal Acetylene InhibitorPeter W. Fan, Chungang Gu, Sandra A. Marsh and Jeffrey C. StevensDrug Metabolism and Disposition January 2003, 31 (1) 28-36; DOI: https://doi.org/10.1124/dmd.31.1.28
Farrell, K.
- You have accessAmino Acid Conjugates: Metabolites of 2-Propylpentanoic Acid (Valproic Acid) in Epileptic PatientsV. S. Gopaul, W. Tang, K. Farrell and F. S. AbbottDrug Metabolism and Disposition January 2003, 31 (1) 114-121; DOI: https://doi.org/10.1124/dmd.31.1.114
G
Gades, Naomi M.
- You have accessCocaethylene Metabolism and Interaction with Cocaine and Ethanol: Role of CarboxylesterasesS. Casey Laizure, Timothy Mandrell, Naomi M. Gades and Robert B. ParkerDrug Metabolism and Disposition January 2003, 31 (1) 16-20; DOI: https://doi.org/10.1124/dmd.31.1.16
Gan, Liang-Shang
- You have accessMetabolism of (S)-5,6-Difluoro-4-cyclopropylethynyl-4-trifluoromethyl-3, 4-dihydro-2(1H)-quinazolinone, a Non-Nucleoside Reverse Transcriptase Inhibitor, in Human Liver Microsomes. Metabolic Activation and Enzyme KineticsHao Chen, Weiqi Chen, Liang-Shang Gan and Abdul E. MutlibDrug Metabolism and Disposition January 2003, 31 (1) 122-132; DOI: https://doi.org/10.1124/dmd.31.1.122
Ghosh, Shobha
- You have accessExpression and Cyclic Variability of CYP3A4 and CYP3A7 Isoforms in Human Endometrium and Cervix During the Menstrual CycleMohamadi A. Sarkar, Vijay Vadlamuri, Shobha Ghosh and Douglas D. GloverDrug Metabolism and Disposition January 2003, 31 (1) 1-6; DOI: https://doi.org/10.1124/dmd.31.1.1
Glover, Douglas D.
- You have accessExpression and Cyclic Variability of CYP3A4 and CYP3A7 Isoforms in Human Endometrium and Cervix During the Menstrual CycleMohamadi A. Sarkar, Vijay Vadlamuri, Shobha Ghosh and Douglas D. GloverDrug Metabolism and Disposition January 2003, 31 (1) 1-6; DOI: https://doi.org/10.1124/dmd.31.1.1
Gopaul, V. S.
- You have accessAmino Acid Conjugates: Metabolites of 2-Propylpentanoic Acid (Valproic Acid) in Epileptic PatientsV. S. Gopaul, W. Tang, K. Farrell and F. S. AbbottDrug Metabolism and Disposition January 2003, 31 (1) 114-121; DOI: https://doi.org/10.1124/dmd.31.1.114
Greenblatt, David J.
- You have accessValidation of Serotonin (5-Hydroxtryptamine) as an in Vitro Substrate Probe for Human UDP-Glucuronosyltransferase (UGT) 1A6Soundararajan Krishnaswamy, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt and Michael H. CourtDrug Metabolism and Disposition January 2003, 31 (1) 133-139; DOI: https://doi.org/10.1124/dmd.31.1.133
Gu, Chungang
- You have accessMechanism-Based Inactivation of Cytochrome P450 2B6 by a Novel Terminal Acetylene InhibitorPeter W. Fan, Chungang Gu, Sandra A. Marsh and Jeffrey C. StevensDrug Metabolism and Disposition January 2003, 31 (1) 28-36; DOI: https://doi.org/10.1124/dmd.31.1.28
H
Hagima, Naoko
- You have accessDifferences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and IntestineTakahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi YamazoeDrug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60
Hanioka, Nobumitsu
- You have accessGlucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486DHideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi SawadaDrug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108
Hochman, Jerome H.
- You have accessAcyl Glucuronidation and Glucosidation of a New and Selective Endothelin ETA Receptor Antagonist in Human Liver MicrosomesCuyue Tang, Jerome H. Hochman, Bennett Ma, Raju Subramanian and Kamlesh P. VyasDrug Metabolism and Disposition January 2003, 31 (1) 37-45; DOI: https://doi.org/10.1124/dmd.31.1.37
Hollenberg, Paul F.
- You have accessThe Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by PhencyclidineMonica I. Jushchyshyn, Ute M. Kent and Paul F. HollenbergDrug Metabolism and Disposition January 2003, 31 (1) 46-52; DOI: https://doi.org/10.1124/dmd.31.1.46
I
Inoue, Hiroki
- You have accessBisphenol A Glucuronidation and Absorption in Rat IntestineHiroki Inoue, Go Yuki, Hiroshi Yokota and Seiyu KatoDrug Metabolism and Disposition January 2003, 31 (1) 140-144; DOI: https://doi.org/10.1124/dmd.31.1.140
Ishida, Seiichi
- You have accessGlucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486DHideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi SawadaDrug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108
Iyer, Ramaswamy A.
- You have accessComparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and HumansRamaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin KripalaniDrug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67
J
Jaw-Tsai, Sarah
- You have accessMetabolism, Pharmacokinetics, and Excretion of a Highly SelectiveN-Methyl-d-aspartate Receptor Antagonist, Traxoprodil, in Human Cytochrome P450 2D6 Extensive and Poor MetabolizersKim Johnson, Ajit Shah, Sarah Jaw-Tsai, James Baxter and Chandra PrakashDrug Metabolism and Disposition January 2003, 31 (1) 76-87; DOI: https://doi.org/10.1124/dmd.31.1.76
Jinno, Hideto
- You have accessGlucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486DHideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi SawadaDrug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108
Johnson, Kim
- You have accessMetabolism, Pharmacokinetics, and Excretion of a Highly SelectiveN-Methyl-d-aspartate Receptor Antagonist, Traxoprodil, in Human Cytochrome P450 2D6 Extensive and Poor MetabolizersKim Johnson, Ajit Shah, Sarah Jaw-Tsai, James Baxter and Chandra PrakashDrug Metabolism and Disposition January 2003, 31 (1) 76-87; DOI: https://doi.org/10.1124/dmd.31.1.76
Jushchyshyn, Monica I.
- You have accessThe Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by PhencyclidineMonica I. Jushchyshyn, Ute M. Kent and Paul F. HollenbergDrug Metabolism and Disposition January 2003, 31 (1) 46-52; DOI: https://doi.org/10.1124/dmd.31.1.46
K
Kato, Seiyu
- You have accessBisphenol A Glucuronidation and Absorption in Rat IntestineHiroki Inoue, Go Yuki, Hiroshi Yokota and Seiyu KatoDrug Metabolism and Disposition January 2003, 31 (1) 140-144; DOI: https://doi.org/10.1124/dmd.31.1.140
Kent, Ute M.
- You have accessThe Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by PhencyclidineMonica I. Jushchyshyn, Ute M. Kent and Paul F. HollenbergDrug Metabolism and Disposition January 2003, 31 (1) 46-52; DOI: https://doi.org/10.1124/dmd.31.1.46
Khan, Sanaullah
- You have accessComparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and HumansRamaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin KripalaniDrug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67
Kohno, Yoshiro
- You have accessDifferences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and IntestineTakahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi YamazoeDrug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60
Kripalani, Kishin
- You have accessComparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and HumansRamaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin KripalaniDrug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67
Krishnaswamy, Soundararajan
- You have accessValidation of Serotonin (5-Hydroxtryptamine) as an in Vitro Substrate Probe for Human UDP-Glucuronosyltransferase (UGT) 1A6Soundararajan Krishnaswamy, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt and Michael H. CourtDrug Metabolism and Disposition January 2003, 31 (1) 133-139; DOI: https://doi.org/10.1124/dmd.31.1.133
Kuo, Fengjiun
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle DogEdward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael SauerDrug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
L
Laizure, S. Casey
- You have accessCocaethylene Metabolism and Interaction with Cocaine and Ethanol: Role of CarboxylesterasesS. Casey Laizure, Timothy Mandrell, Naomi M. Gades and Robert B. ParkerDrug Metabolism and Disposition January 2003, 31 (1) 16-20; DOI: https://doi.org/10.1124/dmd.31.1.16
Leslie, Elaine M.
- You have accessBioflavonoid Stimulation of Glutathione Transport by the 190-kDa Multidrug Resistance Protein 1 (MRP1)Elaine M. Leslie, Roger G. Deeley and Susan P. C. ColeDrug Metabolism and Disposition January 2003, 31 (1) 11-15; DOI: https://doi.org/10.1124/dmd.31.1.11
Li, Qimin
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle DogEdward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael SauerDrug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
Long, Amanda J.
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and MetabolismJohn-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. DesanteDrug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98
M
Ma, Bennett
- You have accessAcyl Glucuronidation and Glucosidation of a New and Selective Endothelin ETA Receptor Antagonist in Human Liver MicrosomesCuyue Tang, Jerome H. Hochman, Bennett Ma, Raju Subramanian and Kamlesh P. VyasDrug Metabolism and Disposition January 2003, 31 (1) 37-45; DOI: https://doi.org/10.1124/dmd.31.1.37
Malhotra, Bimal
- You have accessComparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and HumansRamaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin KripalaniDrug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67
Mandrell, Timothy
- You have accessCocaethylene Metabolism and Interaction with Cocaine and Ethanol: Role of CarboxylesterasesS. Casey Laizure, Timothy Mandrell, Naomi M. Gades and Robert B. ParkerDrug Metabolism and Disposition January 2003, 31 (1) 16-20; DOI: https://doi.org/10.1124/dmd.31.1.16
Marsh, Sandra A.
- You have accessMechanism-Based Inactivation of Cytochrome P450 2B6 by a Novel Terminal Acetylene InhibitorPeter W. Fan, Chungang Gu, Sandra A. Marsh and Jeffrey C. StevensDrug Metabolism and Disposition January 2003, 31 (1) 28-36; DOI: https://doi.org/10.1124/dmd.31.1.28
Mattiuz, Edward L.
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle DogEdward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael SauerDrug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and MetabolismJohn-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. DesanteDrug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98
Mitroka, James
- You have accessComparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and HumansRamaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin KripalaniDrug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67
Mullen, John H.
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle DogEdward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael SauerDrug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
Mutlib, Abdul E.
- You have accessMetabolism of (S)-5,6-Difluoro-4-cyclopropylethynyl-4-trifluoromethyl-3, 4-dihydro-2(1H)-quinazolinone, a Non-Nucleoside Reverse Transcriptase Inhibitor, in Human Liver Microsomes. Metabolic Activation and Enzyme KineticsHao Chen, Weiqi Chen, Liang-Shang Gan and Abdul E. MutlibDrug Metabolism and Disposition January 2003, 31 (1) 122-132; DOI: https://doi.org/10.1124/dmd.31.1.122
N
Nagata, Kiyoshi
- You have accessDifferences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and IntestineTakahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi YamazoeDrug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60
Nakamura, Masato
- You have accessDifferences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and IntestineTakahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi YamazoeDrug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60
Nishimura, Tetsuji
- You have accessGlucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486DHideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi SawadaDrug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108
O
Ozawa, Shogo
- You have accessGlucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486DHideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi SawadaDrug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108
P
Parker, Robert B.
- You have accessCocaethylene Metabolism and Interaction with Cocaine and Ethanol: Role of CarboxylesterasesS. Casey Laizure, Timothy Mandrell, Naomi M. Gades and Robert B. ParkerDrug Metabolism and Disposition January 2003, 31 (1) 16-20; DOI: https://doi.org/10.1124/dmd.31.1.16
Ponsler, G. Douglas
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle DogEdward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael SauerDrug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and MetabolismJohn-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. DesanteDrug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98
Prakash, Chandra
- You have accessMetabolism, Pharmacokinetics, and Excretion of a Highly SelectiveN-Methyl-d-aspartate Receptor Antagonist, Traxoprodil, in Human Cytochrome P450 2D6 Extensive and Poor MetabolizersKim Johnson, Ajit Shah, Sarah Jaw-Tsai, James Baxter and Chandra PrakashDrug Metabolism and Disposition January 2003, 31 (1) 76-87; DOI: https://doi.org/10.1124/dmd.31.1.76
R
Rinehart, J. Kent
- You have accessComparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and HumansRamaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin KripalaniDrug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67
Rochat, Bertrand
- You have accessEvaluation of Recombinant Cytochromes P450 Activity in Metabolic PathwaysBertrand RochatDrug Metabolism and Disposition January 2003, 31 (1) 145-146; DOI: https://doi.org/10.1124/dmd.31.1.145
S
Saeki, Mayumi
- You have accessGlucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486DHideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi SawadaDrug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108
Saito, Yoshiro
- You have accessGlucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486DHideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi SawadaDrug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108
Sarkar, Mohamadi A.
- You have accessExpression and Cyclic Variability of CYP3A4 and CYP3A7 Isoforms in Human Endometrium and Cervix During the Menstrual CycleMohamadi A. Sarkar, Vijay Vadlamuri, Shobha Ghosh and Douglas D. GloverDrug Metabolism and Disposition January 2003, 31 (1) 1-6; DOI: https://doi.org/10.1124/dmd.31.1.1
Sauer, John-Michael
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle DogEdward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael SauerDrug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and MetabolismJohn-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. DesanteDrug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98
Sawada, Jun-ichi
- You have accessGlucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486DHideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi SawadaDrug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108
Shah, Ajit
- You have accessMetabolism, Pharmacokinetics, and Excretion of a Highly SelectiveN-Methyl-d-aspartate Receptor Antagonist, Traxoprodil, in Human Cytochrome P450 2D6 Extensive and Poor MetabolizersKim Johnson, Ajit Shah, Sarah Jaw-Tsai, James Baxter and Chandra PrakashDrug Metabolism and Disposition January 2003, 31 (1) 76-87; DOI: https://doi.org/10.1124/dmd.31.1.76
Shugert, Richard L.
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle DogEdward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael SauerDrug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
Stevens, Jeffrey C.
- You have accessMechanism-Based Inactivation of Cytochrome P450 2B6 by a Novel Terminal Acetylene InhibitorPeter W. Fan, Chungang Gu, Sandra A. Marsh and Jeffrey C. StevensDrug Metabolism and Disposition January 2003, 31 (1) 28-36; DOI: https://doi.org/10.1124/dmd.31.1.28
Subramanian, Raju
- You have accessAcyl Glucuronidation and Glucosidation of a New and Selective Endothelin ETA Receptor Antagonist in Human Liver MicrosomesCuyue Tang, Jerome H. Hochman, Bennett Ma, Raju Subramanian and Kamlesh P. VyasDrug Metabolism and Disposition January 2003, 31 (1) 37-45; DOI: https://doi.org/10.1124/dmd.31.1.37
T
Tanaka-Kagawa, Toshiko
- You have accessGlucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486DHideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi SawadaDrug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108
Tang, Cuyue
- You have accessAcyl Glucuronidation and Glucosidation of a New and Selective Endothelin ETA Receptor Antagonist in Human Liver MicrosomesCuyue Tang, Jerome H. Hochman, Bennett Ma, Raju Subramanian and Kamlesh P. VyasDrug Metabolism and Disposition January 2003, 31 (1) 37-45; DOI: https://doi.org/10.1124/dmd.31.1.37
Tang, W.
- You have accessAmino Acid Conjugates: Metabolites of 2-Propylpentanoic Acid (Valproic Acid) in Epileptic PatientsV. S. Gopaul, W. Tang, K. Farrell and F. S. AbbottDrug Metabolism and Disposition January 2003, 31 (1) 114-121; DOI: https://doi.org/10.1124/dmd.31.1.114
Thomasson, Holly R.
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and MetabolismJohn-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. DesanteDrug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98
V
Vadlamuri, Vijay
- You have accessExpression and Cyclic Variability of CYP3A4 and CYP3A7 Isoforms in Human Endometrium and Cervix During the Menstrual CycleMohamadi A. Sarkar, Vijay Vadlamuri, Shobha Ghosh and Douglas D. GloverDrug Metabolism and Disposition January 2003, 31 (1) 1-6; DOI: https://doi.org/10.1124/dmd.31.1.1
von Moltke, Lisa L.
- You have accessValidation of Serotonin (5-Hydroxtryptamine) as an in Vitro Substrate Probe for Human UDP-Glucuronosyltransferase (UGT) 1A6Soundararajan Krishnaswamy, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt and Michael H. CourtDrug Metabolism and Disposition January 2003, 31 (1) 133-139; DOI: https://doi.org/10.1124/dmd.31.1.133
Vyas, Kamlesh P.
- You have accessAcyl Glucuronidation and Glucosidation of a New and Selective Endothelin ETA Receptor Antagonist in Human Liver MicrosomesCuyue Tang, Jerome H. Hochman, Bennett Ma, Raju Subramanian and Kamlesh P. VyasDrug Metabolism and Disposition January 2003, 31 (1) 37-45; DOI: https://doi.org/10.1124/dmd.31.1.37
W
Waller, Stephen C.
- You have accessComparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and HumansRamaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin KripalaniDrug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67
Waskell, Lucy A.
- You have accessThe Metabolism of Clopidogrel Is Catalyzed by Human Cytochrome P450 3A and Is Inhibited by AtorvastatinThomas A. Clarke and Lucy A. WaskellDrug Metabolism and Disposition January 2003, 31 (1) 53-59; DOI: https://doi.org/10.1124/dmd.31.1.53
Wheeler, William J.
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle DogEdward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael SauerDrug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
Witcher, Jennifer W.
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and MetabolismJohn-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. DesanteDrug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98
Wood, Paul G.
- You have accessDisposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle DogEdward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael SauerDrug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
Wu, Micheal
- You have accessMouse Liver and Kidney Carboxylesterase (M-LK) Rapidly Hydrolyzes Antitumor Prodrug Irinotecan and the N-Terminal Three Quarter Sequence Determines Substrate SelectivityMingxing Xie, Dongfang Yang, Micheal Wu, Bob Xue and Bingfang YanDrug Metabolism and Disposition January 2003, 31 (1) 21-27; DOI: https://doi.org/10.1124/dmd.31.1.21
X
Xie, Mingxing
- You have accessMouse Liver and Kidney Carboxylesterase (M-LK) Rapidly Hydrolyzes Antitumor Prodrug Irinotecan and the N-Terminal Three Quarter Sequence Determines Substrate SelectivityMingxing Xie, Dongfang Yang, Micheal Wu, Bob Xue and Bingfang YanDrug Metabolism and Disposition January 2003, 31 (1) 21-27; DOI: https://doi.org/10.1124/dmd.31.1.21
Xue, Bob
- You have accessMouse Liver and Kidney Carboxylesterase (M-LK) Rapidly Hydrolyzes Antitumor Prodrug Irinotecan and the N-Terminal Three Quarter Sequence Determines Substrate SelectivityMingxing Xie, Dongfang Yang, Micheal Wu, Bob Xue and Bingfang YanDrug Metabolism and Disposition January 2003, 31 (1) 21-27; DOI: https://doi.org/10.1124/dmd.31.1.21
Y
Yamamoto, Takahito
- You have accessDifferences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and IntestineTakahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi YamazoeDrug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60
Yamazoe, Yasushi
- You have accessDifferences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and IntestineTakahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi YamazoeDrug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60
Yan, Bingfang
- You have accessMouse Liver and Kidney Carboxylesterase (M-LK) Rapidly Hydrolyzes Antitumor Prodrug Irinotecan and the N-Terminal Three Quarter Sequence Determines Substrate SelectivityMingxing Xie, Dongfang Yang, Micheal Wu, Bob Xue and Bingfang YanDrug Metabolism and Disposition January 2003, 31 (1) 21-27; DOI: https://doi.org/10.1124/dmd.31.1.21
Yang, Dongfang
- You have accessMouse Liver and Kidney Carboxylesterase (M-LK) Rapidly Hydrolyzes Antitumor Prodrug Irinotecan and the N-Terminal Three Quarter Sequence Determines Substrate SelectivityMingxing Xie, Dongfang Yang, Micheal Wu, Bob Xue and Bingfang YanDrug Metabolism and Disposition January 2003, 31 (1) 21-27; DOI: https://doi.org/10.1124/dmd.31.1.21
Yokota, Hiroshi
- You have accessBisphenol A Glucuronidation and Absorption in Rat IntestineHiroki Inoue, Go Yuki, Hiroshi Yokota and Seiyu KatoDrug Metabolism and Disposition January 2003, 31 (1) 140-144; DOI: https://doi.org/10.1124/dmd.31.1.140
Yuki, Go
- You have accessBisphenol A Glucuronidation and Absorption in Rat IntestineHiroki Inoue, Go Yuki, Hiroshi Yokota and Seiyu KatoDrug Metabolism and Disposition January 2003, 31 (1) 140-144; DOI: https://doi.org/10.1124/dmd.31.1.140