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Index by author

January 01, 2003; Volume 31,Issue 1

A

  1. Abbott, F. S.

    1. Amino Acid Conjugates: Metabolites of 2-Propylpentanoic Acid (Valproic Acid) in Epileptic Patients
      V. S. Gopaul, W. Tang, K. Farrell and F. S. Abbott
      Drug Metabolism and Disposition January 2003, 31 (1) 114-121; DOI: https://doi.org/10.1124/dmd.31.1.114

  2. Ando, Masanori

    1. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486D
      Hideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108

B

  1. Bandiera, Stelvio M.

    1. Constitutive Androstane Receptor and Pregnane X Receptor Gene Expression in Human Liver: Interindividual Variability and Correlation with CYP2B6 mRNA Levels
      Thomas K. H. Chang, Stelvio M. Bandiera and Jie Chen
      Drug Metabolism and Disposition January 2003, 31 (1) 7-10; DOI: https://doi.org/10.1124/dmd.31.1.7

  2. Barbuch, Robert J.

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle Dog
      Edward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael Sauer
      Drug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88

  3. Baxter, James

    1. Metabolism, Pharmacokinetics, and Excretion of a Highly SelectiveN-Methyl-d-aspartate Receptor Antagonist, Traxoprodil, in Human Cytochrome P450 2D6 Extensive and Poor Metabolizers
      Kim Johnson, Ajit Shah, Sarah Jaw-Tsai, James Baxter and Chandra Prakash
      Drug Metabolism and Disposition January 2003, 31 (1) 76-87; DOI: https://doi.org/10.1124/dmd.31.1.76

  4. Bonacorsi, Samuel

    1. Comparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and Humans
      Ramaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin Kripalani
      Drug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67

C

  1. Chang, Thomas K. H.

    1. Constitutive Androstane Receptor and Pregnane X Receptor Gene Expression in Human Liver: Interindividual Variability and Correlation with CYP2B6 mRNA Levels
      Thomas K. H. Chang, Stelvio M. Bandiera and Jie Chen
      Drug Metabolism and Disposition January 2003, 31 (1) 7-10; DOI: https://doi.org/10.1124/dmd.31.1.7

  2. Chen, Hao

    1. Metabolism of (S)-5,6-Difluoro-4-cyclopropylethynyl-4-trifluoromethyl-3, 4-dihydro-2(1H)-quinazolinone, a Non-Nucleoside Reverse Transcriptase Inhibitor, in Human Liver Microsomes. Metabolic Activation and Enzyme Kinetics
      Hao Chen, Weiqi Chen, Liang-Shang Gan and Abdul E. Mutlib
      Drug Metabolism and Disposition January 2003, 31 (1) 122-132; DOI: https://doi.org/10.1124/dmd.31.1.122

  3. Chen, Jie

    1. Constitutive Androstane Receptor and Pregnane X Receptor Gene Expression in Human Liver: Interindividual Variability and Correlation with CYP2B6 mRNA Levels
      Thomas K. H. Chang, Stelvio M. Bandiera and Jie Chen
      Drug Metabolism and Disposition January 2003, 31 (1) 7-10; DOI: https://doi.org/10.1124/dmd.31.1.7

  4. Chen, Weiqi

    1. Metabolism of (S)-5,6-Difluoro-4-cyclopropylethynyl-4-trifluoromethyl-3, 4-dihydro-2(1H)-quinazolinone, a Non-Nucleoside Reverse Transcriptase Inhibitor, in Human Liver Microsomes. Metabolic Activation and Enzyme Kinetics
      Hao Chen, Weiqi Chen, Liang-Shang Gan and Abdul E. Mutlib
      Drug Metabolism and Disposition January 2003, 31 (1) 122-132; DOI: https://doi.org/10.1124/dmd.31.1.122

  5. Clarke, Thomas A.

    1. The Metabolism of Clopidogrel Is Catalyzed by Human Cytochrome P450 3A and Is Inhibited by Atorvastatin
      Thomas A. Clarke and Lucy A. Waskell
      Drug Metabolism and Disposition January 2003, 31 (1) 53-59; DOI: https://doi.org/10.1124/dmd.31.1.53

  6. Cole, Susan P. C.

    1. Bioflavonoid Stimulation of Glutathione Transport by the 190-kDa Multidrug Resistance Protein 1 (MRP1)
      Elaine M. Leslie, Roger G. Deeley and Susan P. C. Cole
      Drug Metabolism and Disposition January 2003, 31 (1) 11-15; DOI: https://doi.org/10.1124/dmd.31.1.11

  7. Conrad, Preston C.

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle Dog
      Edward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael Sauer
      Drug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88

  8. Court, Michael H.

    1. Validation of Serotonin (5-Hydroxtryptamine) as an in Vitro Substrate Probe for Human UDP-Glucuronosyltransferase (UGT) 1A6
      Soundararajan Krishnaswamy, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt and Michael H. Court
      Drug Metabolism and Disposition January 2003, 31 (1) 133-139; DOI: https://doi.org/10.1124/dmd.31.1.133

D

  1. Deeley, Roger G.

    1. Bioflavonoid Stimulation of Glutathione Transport by the 190-kDa Multidrug Resistance Protein 1 (MRP1)
      Elaine M. Leslie, Roger G. Deeley and Susan P. C. Cole
      Drug Metabolism and Disposition January 2003, 31 (1) 11-15; DOI: https://doi.org/10.1124/dmd.31.1.11

  2. Desante, Karl A.

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and Metabolism
      John-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. Desante
      Drug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98

  3. Duan, Su X.

    1. Validation of Serotonin (5-Hydroxtryptamine) as an in Vitro Substrate Probe for Human UDP-Glucuronosyltransferase (UGT) 1A6
      Soundararajan Krishnaswamy, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt and Michael H. Court
      Drug Metabolism and Disposition January 2003, 31 (1) 133-139; DOI: https://doi.org/10.1124/dmd.31.1.133

F

  1. Fan, Peter W.

    1. Mechanism-Based Inactivation of Cytochrome P450 2B6 by a Novel Terminal Acetylene Inhibitor
      Peter W. Fan, Chungang Gu, Sandra A. Marsh and Jeffrey C. Stevens
      Drug Metabolism and Disposition January 2003, 31 (1) 28-36; DOI: https://doi.org/10.1124/dmd.31.1.28

  2. Farrell, K.

    1. Amino Acid Conjugates: Metabolites of 2-Propylpentanoic Acid (Valproic Acid) in Epileptic Patients
      V. S. Gopaul, W. Tang, K. Farrell and F. S. Abbott
      Drug Metabolism and Disposition January 2003, 31 (1) 114-121; DOI: https://doi.org/10.1124/dmd.31.1.114

G

  1. Gades, Naomi M.

    1. Cocaethylene Metabolism and Interaction with Cocaine and Ethanol: Role of Carboxylesterases
      S. Casey Laizure, Timothy Mandrell, Naomi M. Gades and Robert B. Parker
      Drug Metabolism and Disposition January 2003, 31 (1) 16-20; DOI: https://doi.org/10.1124/dmd.31.1.16

  2. Gan, Liang-Shang

    1. Metabolism of (S)-5,6-Difluoro-4-cyclopropylethynyl-4-trifluoromethyl-3, 4-dihydro-2(1H)-quinazolinone, a Non-Nucleoside Reverse Transcriptase Inhibitor, in Human Liver Microsomes. Metabolic Activation and Enzyme Kinetics
      Hao Chen, Weiqi Chen, Liang-Shang Gan and Abdul E. Mutlib
      Drug Metabolism and Disposition January 2003, 31 (1) 122-132; DOI: https://doi.org/10.1124/dmd.31.1.122

  3. Ghosh, Shobha

    1. Expression and Cyclic Variability of CYP3A4 and CYP3A7 Isoforms in Human Endometrium and Cervix During the Menstrual Cycle
      Mohamadi A. Sarkar, Vijay Vadlamuri, Shobha Ghosh and Douglas D. Glover
      Drug Metabolism and Disposition January 2003, 31 (1) 1-6; DOI: https://doi.org/10.1124/dmd.31.1.1

  4. Glover, Douglas D.

    1. Expression and Cyclic Variability of CYP3A4 and CYP3A7 Isoforms in Human Endometrium and Cervix During the Menstrual Cycle
      Mohamadi A. Sarkar, Vijay Vadlamuri, Shobha Ghosh and Douglas D. Glover
      Drug Metabolism and Disposition January 2003, 31 (1) 1-6; DOI: https://doi.org/10.1124/dmd.31.1.1

  5. Gopaul, V. S.

    1. Amino Acid Conjugates: Metabolites of 2-Propylpentanoic Acid (Valproic Acid) in Epileptic Patients
      V. S. Gopaul, W. Tang, K. Farrell and F. S. Abbott
      Drug Metabolism and Disposition January 2003, 31 (1) 114-121; DOI: https://doi.org/10.1124/dmd.31.1.114

  6. Greenblatt, David J.

    1. Validation of Serotonin (5-Hydroxtryptamine) as an in Vitro Substrate Probe for Human UDP-Glucuronosyltransferase (UGT) 1A6
      Soundararajan Krishnaswamy, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt and Michael H. Court
      Drug Metabolism and Disposition January 2003, 31 (1) 133-139; DOI: https://doi.org/10.1124/dmd.31.1.133

  7. Gu, Chungang

    1. Mechanism-Based Inactivation of Cytochrome P450 2B6 by a Novel Terminal Acetylene Inhibitor
      Peter W. Fan, Chungang Gu, Sandra A. Marsh and Jeffrey C. Stevens
      Drug Metabolism and Disposition January 2003, 31 (1) 28-36; DOI: https://doi.org/10.1124/dmd.31.1.28

H

  1. Hagima, Naoko

    1. Differences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and Intestine
      Takahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60

  2. Hanioka, Nobumitsu

    1. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486D
      Hideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108

  3. Hochman, Jerome H.

    1. Acyl Glucuronidation and Glucosidation of a New and Selective Endothelin ETA Receptor Antagonist in Human Liver Microsomes
      Cuyue Tang, Jerome H. Hochman, Bennett Ma, Raju Subramanian and Kamlesh P. Vyas
      Drug Metabolism and Disposition January 2003, 31 (1) 37-45; DOI: https://doi.org/10.1124/dmd.31.1.37

  4. Hollenberg, Paul F.

    1. The Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Phencyclidine
      Monica I. Jushchyshyn, Ute M. Kent and Paul F. Hollenberg
      Drug Metabolism and Disposition January 2003, 31 (1) 46-52; DOI: https://doi.org/10.1124/dmd.31.1.46

I

  1. Inoue, Hiroki

    1. Bisphenol A Glucuronidation and Absorption in Rat Intestine
      Hiroki Inoue, Go Yuki, Hiroshi Yokota and Seiyu Kato
      Drug Metabolism and Disposition January 2003, 31 (1) 140-144; DOI: https://doi.org/10.1124/dmd.31.1.140

  2. Ishida, Seiichi

    1. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486D
      Hideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108

  3. Iyer, Ramaswamy A.

    1. Comparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and Humans
      Ramaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin Kripalani
      Drug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67

J

  1. Jaw-Tsai, Sarah

    1. Metabolism, Pharmacokinetics, and Excretion of a Highly SelectiveN-Methyl-d-aspartate Receptor Antagonist, Traxoprodil, in Human Cytochrome P450 2D6 Extensive and Poor Metabolizers
      Kim Johnson, Ajit Shah, Sarah Jaw-Tsai, James Baxter and Chandra Prakash
      Drug Metabolism and Disposition January 2003, 31 (1) 76-87; DOI: https://doi.org/10.1124/dmd.31.1.76

  2. Jinno, Hideto

    1. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486D
      Hideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108

  3. Johnson, Kim

    1. Metabolism, Pharmacokinetics, and Excretion of a Highly SelectiveN-Methyl-d-aspartate Receptor Antagonist, Traxoprodil, in Human Cytochrome P450 2D6 Extensive and Poor Metabolizers
      Kim Johnson, Ajit Shah, Sarah Jaw-Tsai, James Baxter and Chandra Prakash
      Drug Metabolism and Disposition January 2003, 31 (1) 76-87; DOI: https://doi.org/10.1124/dmd.31.1.76

  4. Jushchyshyn, Monica I.

    1. The Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Phencyclidine
      Monica I. Jushchyshyn, Ute M. Kent and Paul F. Hollenberg
      Drug Metabolism and Disposition January 2003, 31 (1) 46-52; DOI: https://doi.org/10.1124/dmd.31.1.46

K

  1. Kato, Seiyu

    1. Bisphenol A Glucuronidation and Absorption in Rat Intestine
      Hiroki Inoue, Go Yuki, Hiroshi Yokota and Seiyu Kato
      Drug Metabolism and Disposition January 2003, 31 (1) 140-144; DOI: https://doi.org/10.1124/dmd.31.1.140

  2. Kent, Ute M.

    1. The Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Phencyclidine
      Monica I. Jushchyshyn, Ute M. Kent and Paul F. Hollenberg
      Drug Metabolism and Disposition January 2003, 31 (1) 46-52; DOI: https://doi.org/10.1124/dmd.31.1.46

  3. Khan, Sanaullah

    1. Comparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and Humans
      Ramaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin Kripalani
      Drug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67

  4. Kohno, Yoshiro

    1. Differences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and Intestine
      Takahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60

  5. Kripalani, Kishin

    1. Comparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and Humans
      Ramaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin Kripalani
      Drug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67

  6. Krishnaswamy, Soundararajan

    1. Validation of Serotonin (5-Hydroxtryptamine) as an in Vitro Substrate Probe for Human UDP-Glucuronosyltransferase (UGT) 1A6
      Soundararajan Krishnaswamy, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt and Michael H. Court
      Drug Metabolism and Disposition January 2003, 31 (1) 133-139; DOI: https://doi.org/10.1124/dmd.31.1.133

  7. Kuo, Fengjiun

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle Dog
      Edward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael Sauer
      Drug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88

L

  1. Laizure, S. Casey

    1. Cocaethylene Metabolism and Interaction with Cocaine and Ethanol: Role of Carboxylesterases
      S. Casey Laizure, Timothy Mandrell, Naomi M. Gades and Robert B. Parker
      Drug Metabolism and Disposition January 2003, 31 (1) 16-20; DOI: https://doi.org/10.1124/dmd.31.1.16

  2. Leslie, Elaine M.

    1. Bioflavonoid Stimulation of Glutathione Transport by the 190-kDa Multidrug Resistance Protein 1 (MRP1)
      Elaine M. Leslie, Roger G. Deeley and Susan P. C. Cole
      Drug Metabolism and Disposition January 2003, 31 (1) 11-15; DOI: https://doi.org/10.1124/dmd.31.1.11

  3. Li, Qimin

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle Dog
      Edward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael Sauer
      Drug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88

  4. Long, Amanda J.

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and Metabolism
      John-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. Desante
      Drug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98

M

  1. Ma, Bennett

    1. Acyl Glucuronidation and Glucosidation of a New and Selective Endothelin ETA Receptor Antagonist in Human Liver Microsomes
      Cuyue Tang, Jerome H. Hochman, Bennett Ma, Raju Subramanian and Kamlesh P. Vyas
      Drug Metabolism and Disposition January 2003, 31 (1) 37-45; DOI: https://doi.org/10.1124/dmd.31.1.37

  2. Malhotra, Bimal

    1. Comparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and Humans
      Ramaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin Kripalani
      Drug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67

  3. Mandrell, Timothy

    1. Cocaethylene Metabolism and Interaction with Cocaine and Ethanol: Role of Carboxylesterases
      S. Casey Laizure, Timothy Mandrell, Naomi M. Gades and Robert B. Parker
      Drug Metabolism and Disposition January 2003, 31 (1) 16-20; DOI: https://doi.org/10.1124/dmd.31.1.16

  4. Marsh, Sandra A.

    1. Mechanism-Based Inactivation of Cytochrome P450 2B6 by a Novel Terminal Acetylene Inhibitor
      Peter W. Fan, Chungang Gu, Sandra A. Marsh and Jeffrey C. Stevens
      Drug Metabolism and Disposition January 2003, 31 (1) 28-36; DOI: https://doi.org/10.1124/dmd.31.1.28

  5. Mattiuz, Edward L.

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle Dog
      Edward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael Sauer
      Drug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
    2. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and Metabolism
      John-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. Desante
      Drug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98

  6. Mitroka, James

    1. Comparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and Humans
      Ramaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin Kripalani
      Drug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67

  7. Mullen, John H.

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle Dog
      Edward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael Sauer
      Drug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88

  8. Mutlib, Abdul E.

    1. Metabolism of (S)-5,6-Difluoro-4-cyclopropylethynyl-4-trifluoromethyl-3, 4-dihydro-2(1H)-quinazolinone, a Non-Nucleoside Reverse Transcriptase Inhibitor, in Human Liver Microsomes. Metabolic Activation and Enzyme Kinetics
      Hao Chen, Weiqi Chen, Liang-Shang Gan and Abdul E. Mutlib
      Drug Metabolism and Disposition January 2003, 31 (1) 122-132; DOI: https://doi.org/10.1124/dmd.31.1.122

N

  1. Nagata, Kiyoshi

    1. Differences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and Intestine
      Takahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60

  2. Nakamura, Masato

    1. Differences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and Intestine
      Takahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60

  3. Nishimura, Tetsuji

    1. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486D
      Hideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108

O

  1. Ozawa, Shogo

    1. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486D
      Hideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108

P

  1. Parker, Robert B.

    1. Cocaethylene Metabolism and Interaction with Cocaine and Ethanol: Role of Carboxylesterases
      S. Casey Laizure, Timothy Mandrell, Naomi M. Gades and Robert B. Parker
      Drug Metabolism and Disposition January 2003, 31 (1) 16-20; DOI: https://doi.org/10.1124/dmd.31.1.16

  2. Ponsler, G. Douglas

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle Dog
      Edward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael Sauer
      Drug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
    2. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and Metabolism
      John-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. Desante
      Drug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98

  3. Prakash, Chandra

    1. Metabolism, Pharmacokinetics, and Excretion of a Highly SelectiveN-Methyl-d-aspartate Receptor Antagonist, Traxoprodil, in Human Cytochrome P450 2D6 Extensive and Poor Metabolizers
      Kim Johnson, Ajit Shah, Sarah Jaw-Tsai, James Baxter and Chandra Prakash
      Drug Metabolism and Disposition January 2003, 31 (1) 76-87; DOI: https://doi.org/10.1124/dmd.31.1.76

R

  1. Rinehart, J. Kent

    1. Comparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and Humans
      Ramaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin Kripalani
      Drug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67

  2. Rochat, Bertrand

    1. Evaluation of Recombinant Cytochromes P450 Activity in Metabolic Pathways
      Bertrand Rochat
      Drug Metabolism and Disposition January 2003, 31 (1) 145-146; DOI: https://doi.org/10.1124/dmd.31.1.145

S

  1. Saeki, Mayumi

    1. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486D
      Hideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108

  2. Saito, Yoshiro

    1. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486D
      Hideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108

  3. Sarkar, Mohamadi A.

    1. Expression and Cyclic Variability of CYP3A4 and CYP3A7 Isoforms in Human Endometrium and Cervix During the Menstrual Cycle
      Mohamadi A. Sarkar, Vijay Vadlamuri, Shobha Ghosh and Douglas D. Glover
      Drug Metabolism and Disposition January 2003, 31 (1) 1-6; DOI: https://doi.org/10.1124/dmd.31.1.1

  4. Sauer, John-Michael

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle Dog
      Edward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael Sauer
      Drug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88
    2. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and Metabolism
      John-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. Desante
      Drug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98

  5. Sawada, Jun-ichi

    1. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486D
      Hideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108

  6. Shah, Ajit

    1. Metabolism, Pharmacokinetics, and Excretion of a Highly SelectiveN-Methyl-d-aspartate Receptor Antagonist, Traxoprodil, in Human Cytochrome P450 2D6 Extensive and Poor Metabolizers
      Kim Johnson, Ajit Shah, Sarah Jaw-Tsai, James Baxter and Chandra Prakash
      Drug Metabolism and Disposition January 2003, 31 (1) 76-87; DOI: https://doi.org/10.1124/dmd.31.1.76

  7. Shugert, Richard L.

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle Dog
      Edward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael Sauer
      Drug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88

  8. Stevens, Jeffrey C.

    1. Mechanism-Based Inactivation of Cytochrome P450 2B6 by a Novel Terminal Acetylene Inhibitor
      Peter W. Fan, Chungang Gu, Sandra A. Marsh and Jeffrey C. Stevens
      Drug Metabolism and Disposition January 2003, 31 (1) 28-36; DOI: https://doi.org/10.1124/dmd.31.1.28

  9. Subramanian, Raju

    1. Acyl Glucuronidation and Glucosidation of a New and Selective Endothelin ETA Receptor Antagonist in Human Liver Microsomes
      Cuyue Tang, Jerome H. Hochman, Bennett Ma, Raju Subramanian and Kamlesh P. Vyas
      Drug Metabolism and Disposition January 2003, 31 (1) 37-45; DOI: https://doi.org/10.1124/dmd.31.1.37

T

  1. Tanaka-Kagawa, Toshiko

    1. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486D
      Hideto Jinno, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Mayumi Saeki, Seiichi Ishida, Tetsuji Nishimura, Masanori Ando, Yoshiro Saito, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition January 2003, 31 (1) 108-113; DOI: https://doi.org/10.1124/dmd.31.1.108

  2. Tang, Cuyue

    1. Acyl Glucuronidation and Glucosidation of a New and Selective Endothelin ETA Receptor Antagonist in Human Liver Microsomes
      Cuyue Tang, Jerome H. Hochman, Bennett Ma, Raju Subramanian and Kamlesh P. Vyas
      Drug Metabolism and Disposition January 2003, 31 (1) 37-45; DOI: https://doi.org/10.1124/dmd.31.1.37

  3. Tang, W.

    1. Amino Acid Conjugates: Metabolites of 2-Propylpentanoic Acid (Valproic Acid) in Epileptic Patients
      V. S. Gopaul, W. Tang, K. Farrell and F. S. Abbott
      Drug Metabolism and Disposition January 2003, 31 (1) 114-121; DOI: https://doi.org/10.1124/dmd.31.1.114

  4. Thomasson, Holly R.

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and Metabolism
      John-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. Desante
      Drug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98

V

  1. Vadlamuri, Vijay

    1. Expression and Cyclic Variability of CYP3A4 and CYP3A7 Isoforms in Human Endometrium and Cervix During the Menstrual Cycle
      Mohamadi A. Sarkar, Vijay Vadlamuri, Shobha Ghosh and Douglas D. Glover
      Drug Metabolism and Disposition January 2003, 31 (1) 1-6; DOI: https://doi.org/10.1124/dmd.31.1.1

  2. von Moltke, Lisa L.

    1. Validation of Serotonin (5-Hydroxtryptamine) as an in Vitro Substrate Probe for Human UDP-Glucuronosyltransferase (UGT) 1A6
      Soundararajan Krishnaswamy, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt and Michael H. Court
      Drug Metabolism and Disposition January 2003, 31 (1) 133-139; DOI: https://doi.org/10.1124/dmd.31.1.133

  3. Vyas, Kamlesh P.

    1. Acyl Glucuronidation and Glucosidation of a New and Selective Endothelin ETA Receptor Antagonist in Human Liver Microsomes
      Cuyue Tang, Jerome H. Hochman, Bennett Ma, Raju Subramanian and Kamlesh P. Vyas
      Drug Metabolism and Disposition January 2003, 31 (1) 37-45; DOI: https://doi.org/10.1124/dmd.31.1.37

W

  1. Waller, Stephen C.

    1. Comparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and Humans
      Ramaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Stephen C. Waller, J. Kent Rinehart and Kishin Kripalani
      Drug Metabolism and Disposition January 2003, 31 (1) 67-75; DOI: https://doi.org/10.1124/dmd.31.1.67

  2. Waskell, Lucy A.

    1. The Metabolism of Clopidogrel Is Catalyzed by Human Cytochrome P450 3A and Is Inhibited by Atorvastatin
      Thomas A. Clarke and Lucy A. Waskell
      Drug Metabolism and Disposition January 2003, 31 (1) 53-59; DOI: https://doi.org/10.1124/dmd.31.1.53

  3. Wheeler, William J.

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle Dog
      Edward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael Sauer
      Drug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88

  4. Witcher, Jennifer W.

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and Metabolism
      John-Michael Sauer, G. Douglas Ponsler, Edward L. Mattiuz, Amanda J. Long, Jennifer W. Witcher, Holly R. Thomasson and Karl A. Desante
      Drug Metabolism and Disposition January 2003, 31 (1) 98-107; DOI: https://doi.org/10.1124/dmd.31.1.98

  5. Wood, Paul G.

    1. Disposition and Metabolic Fate of Atomoxetine Hydrochloride: Pharmacokinetics, Metabolism, and Excretion in the Fischer 344 Rat and Beagle Dog
      Edward L. Mattiuz, G. Douglas Ponsler, Robert J. Barbuch, Paul G. Wood, John H. Mullen, Richard L. Shugert, Qimin Li, William J. Wheeler, Fengjiun Kuo, Preston C. Conrad and John-Michael Sauer
      Drug Metabolism and Disposition January 2003, 31 (1) 88-97; DOI: https://doi.org/10.1124/dmd.31.1.88

  6. Wu, Micheal

    1. Mouse Liver and Kidney Carboxylesterase (M-LK) Rapidly Hydrolyzes Antitumor Prodrug Irinotecan and the N-Terminal Three Quarter Sequence Determines Substrate Selectivity
      Mingxing Xie, Dongfang Yang, Micheal Wu, Bob Xue and Bingfang Yan
      Drug Metabolism and Disposition January 2003, 31 (1) 21-27; DOI: https://doi.org/10.1124/dmd.31.1.21

X

  1. Xie, Mingxing

    1. Mouse Liver and Kidney Carboxylesterase (M-LK) Rapidly Hydrolyzes Antitumor Prodrug Irinotecan and the N-Terminal Three Quarter Sequence Determines Substrate Selectivity
      Mingxing Xie, Dongfang Yang, Micheal Wu, Bob Xue and Bingfang Yan
      Drug Metabolism and Disposition January 2003, 31 (1) 21-27; DOI: https://doi.org/10.1124/dmd.31.1.21

  2. Xue, Bob

    1. Mouse Liver and Kidney Carboxylesterase (M-LK) Rapidly Hydrolyzes Antitumor Prodrug Irinotecan and the N-Terminal Three Quarter Sequence Determines Substrate Selectivity
      Mingxing Xie, Dongfang Yang, Micheal Wu, Bob Xue and Bingfang Yan
      Drug Metabolism and Disposition January 2003, 31 (1) 21-27; DOI: https://doi.org/10.1124/dmd.31.1.21

Y

  1. Yamamoto, Takahito

    1. Differences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and Intestine
      Takahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60

  2. Yamazoe, Yasushi

    1. Differences in Cytochrome P450 Forms Involved in the Metabolism ofN,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a Novel Sigma Ligand, in Human Liver and Intestine
      Takahito Yamamoto, Naoko Hagima, Masato Nakamura, Yoshiro Kohno, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition January 2003, 31 (1) 60-66; DOI: https://doi.org/10.1124/dmd.31.1.60

  3. Yan, Bingfang

    1. Mouse Liver and Kidney Carboxylesterase (M-LK) Rapidly Hydrolyzes Antitumor Prodrug Irinotecan and the N-Terminal Three Quarter Sequence Determines Substrate Selectivity
      Mingxing Xie, Dongfang Yang, Micheal Wu, Bob Xue and Bingfang Yan
      Drug Metabolism and Disposition January 2003, 31 (1) 21-27; DOI: https://doi.org/10.1124/dmd.31.1.21

  4. Yang, Dongfang

    1. Mouse Liver and Kidney Carboxylesterase (M-LK) Rapidly Hydrolyzes Antitumor Prodrug Irinotecan and the N-Terminal Three Quarter Sequence Determines Substrate Selectivity
      Mingxing Xie, Dongfang Yang, Micheal Wu, Bob Xue and Bingfang Yan
      Drug Metabolism and Disposition January 2003, 31 (1) 21-27; DOI: https://doi.org/10.1124/dmd.31.1.21

  5. Yokota, Hiroshi

    1. Bisphenol A Glucuronidation and Absorption in Rat Intestine
      Hiroki Inoue, Go Yuki, Hiroshi Yokota and Seiyu Kato
      Drug Metabolism and Disposition January 2003, 31 (1) 140-144; DOI: https://doi.org/10.1124/dmd.31.1.140

  6. Yuki, Go

    1. Bisphenol A Glucuronidation and Absorption in Rat Intestine
      Hiroki Inoue, Go Yuki, Hiroshi Yokota and Seiyu Kato
      Drug Metabolism and Disposition January 2003, 31 (1) 140-144; DOI: https://doi.org/10.1124/dmd.31.1.140
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