Table of Contents

Articles

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  METABOLISM OF (R)-(+)-MENTHOFURAN IN FISCHER-344 RATS: IDENTIFICATION OF SULFONIC ACID METABOLITES

  L.-J. Chen, E. H. Lebetkin and L. T. Burka

  Drug Metabolism and Disposition October 2003, 31 (10) 1208-1213; DOI: https://doi.org/10.1124/dmd.31.10.1208
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  INFLUENCE OF P-GLYCOPROTEIN, TRANSFER CLEARANCES, AND DRUG BINDING ON INTESTINAL METABOLISM IN CACO-2 CELL MONOLAYERS OR MEMBRANE PREPARATIONS: A THEORETICAL ANALYSIS

  Debbie Tam, Huadong Sun and K. Sandy Pang

  Drug Metabolism and Disposition October 2003, 31 (10) 1214-1226; DOI: https://doi.org/10.1124/dmd.31.10.1214
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  STEREOSELECTIVE METABOLISM OF LANSOPRAZOLE BY HUMAN LIVER CYTOCHROME P450 ENZYMES

  Kyoung-Ah Kim, Min-Jung Kim, Ji-Young Park, Ji-Hong Shon, Young-Ran Yoon, Sang-Seop Lee, Kwang-Hyeon Liu, Jin-Ho Chun, Myung-Ho Hyun and Jae-Gook Shin

  Drug Metabolism and Disposition October 2003, 31 (10) 1227-1234; DOI: https://doi.org/10.1124/dmd.31.10.1227
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  EXPRESSION PROFILES OF DRUG-METABOLIZING ENZYME CYP3A AND DRUG EFFLUX TRANSPORTER MULTIDRUG RESISTANCE 1 SUBFAMILY mRNAS IN RAT SMALL INTESTINE

  Kohji Takara, Noriaki Ohnishi, Sayo Horibe and Teruyoshi Yokoyama

  Drug Metabolism and Disposition October 2003, 31 (10) 1235-1239; DOI: https://doi.org/10.1124/dmd.31.10.1235
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  IN VITRO METABOLISM STUDIES ON THE ISOXAZOLE RING SCISSION IN THE ANTI-INFLAMMATORY AGENT LEFLUNOMIDE TO ITS ACTIVE α-CYANOENOL METABOLITE A771726: MECHANISTIC SIMILARITIES WITH THE CYTOCHROME P450-CATALYZED DEHYDRATION OF ALDOXIMES

  Amit S. Kalgutkar, Hang T. Nguyen, Alfin D. N. Vaz, Anke Doan, Deepak K. Dalvie, Dale G. McLeod and John C. Murray

  Drug Metabolism and Disposition October 2003, 31 (10) 1240-1250; DOI: https://doi.org/10.1124/dmd.31.10.1240
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  EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO

  Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii

  Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251
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  PHARMACOKINETICS OF CITALOPRAM IN RELATION TO GENETIC POLYMORPHISM OF CYP2C19

  Bang-Ning Yu, Guo-Lin Chen, Nan He, Dong-Sheng Ouyang, Xiao-Ping Chen, Zhao-Qian Liu and Hong-Hao Zhou

  Drug Metabolism and Disposition October 2003, 31 (10) 1255-1259; DOI: https://doi.org/10.1124/dmd.31.10.1255
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  INSULIN AND GLUCAGON SIGNALING IN REGULATION OF MICROSOMAL EPOXIDE HYDROLASE EXPRESSION IN PRIMARY CULTURED RAT HEPATOCYTES

  Sang K. Kim, Kimberley J. Woodcroft, Sang G. Kim and Raymond F. Novak

  Drug Metabolism and Disposition October 2003, 31 (10) 1260-1268; DOI: https://doi.org/10.1124/dmd.31.10.1260
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  METABOLISM AND PHARMACOKINETICS OF A DIPEPTIDYL PEPTIDASE IV INHIBITOR IN RATS, DOGS, AND MONKEYS WITH SELECTIVE CARBAMOYL GLUCURONIDATION OF THE PRIMARY AMINE IN DOGS

  Maria G. Beconi, Ann Mao, David Q. Liu, Christopher Kochansky, Tony Pereira, Conrad Raab, Paul Pearson and Shuet-Hing Lee Chiu

  Drug Metabolism and Disposition October 2003, 31 (10) 1269-1277; DOI: https://doi.org/10.1124/dmd.31.10.1269