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Drug Metabolism & Disposition

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Index by author

October 01, 2003; Volume 31,Issue 10
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

B

  1. Beconi, Maria G.

    1. You have access
      METABOLISM AND PHARMACOKINETICS OF A DIPEPTIDYL PEPTIDASE IV INHIBITOR IN RATS, DOGS, AND MONKEYS WITH SELECTIVE CARBAMOYL GLUCURONIDATION OF THE PRIMARY AMINE IN DOGS
      Maria G. Beconi, Ann Mao, David Q. Liu, Christopher Kochansky, Tony Pereira, Conrad Raab, Paul Pearson and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition October 2003, 31 (10) 1269-1277; DOI: https://doi.org/10.1124/dmd.31.10.1269
  2. Bruckner, James V.

    1. You have access
      PLASMA BINDING OF TRICHLOROACETIC ACID IN MICE, RATS, AND HUMANS UNDER CANCER BIOASSAY AND ENVIRONMENTAL EXPOSURE CONDITIONS
      Michael H. Lumpkin, James V. Bruckner, Jerry L. Campbell, Cham E. Dallas, Catherine A. White and Jeffrey W. Fisher
      Drug Metabolism and Disposition October 2003, 31 (10) 1203-1207; DOI: https://doi.org/10.1124/dmd.31.10.1203
  3. Burka, L. T.

    1. You have access
      METABOLISM OF (R)-(+)-MENTHOFURAN IN FISCHER-344 RATS: IDENTIFICATION OF SULFONIC ACID METABOLITES
      L.-J. Chen, E. H. Lebetkin and L. T. Burka
      Drug Metabolism and Disposition October 2003, 31 (10) 1208-1213; DOI: https://doi.org/10.1124/dmd.31.10.1208

C

  1. Campbell, Jerry L.

    1. You have access
      PLASMA BINDING OF TRICHLOROACETIC ACID IN MICE, RATS, AND HUMANS UNDER CANCER BIOASSAY AND ENVIRONMENTAL EXPOSURE CONDITIONS
      Michael H. Lumpkin, James V. Bruckner, Jerry L. Campbell, Cham E. Dallas, Catherine A. White and Jeffrey W. Fisher
      Drug Metabolism and Disposition October 2003, 31 (10) 1203-1207; DOI: https://doi.org/10.1124/dmd.31.10.1203
  2. Chen, Guo-Lin

    1. You have access
      PHARMACOKINETICS OF CITALOPRAM IN RELATION TO GENETIC POLYMORPHISM OF CYP2C19
      Bang-Ning Yu, Guo-Lin Chen, Nan He, Dong-Sheng Ouyang, Xiao-Ping Chen, Zhao-Qian Liu and Hong-Hao Zhou
      Drug Metabolism and Disposition October 2003, 31 (10) 1255-1259; DOI: https://doi.org/10.1124/dmd.31.10.1255
  3. Chen, L.-J.

    1. You have access
      METABOLISM OF (R)-(+)-MENTHOFURAN IN FISCHER-344 RATS: IDENTIFICATION OF SULFONIC ACID METABOLITES
      L.-J. Chen, E. H. Lebetkin and L. T. Burka
      Drug Metabolism and Disposition October 2003, 31 (10) 1208-1213; DOI: https://doi.org/10.1124/dmd.31.10.1208
  4. Chen, Xiao-Ping

    1. You have access
      PHARMACOKINETICS OF CITALOPRAM IN RELATION TO GENETIC POLYMORPHISM OF CYP2C19
      Bang-Ning Yu, Guo-Lin Chen, Nan He, Dong-Sheng Ouyang, Xiao-Ping Chen, Zhao-Qian Liu and Hong-Hao Zhou
      Drug Metabolism and Disposition October 2003, 31 (10) 1255-1259; DOI: https://doi.org/10.1124/dmd.31.10.1255
  5. Chiba, Masato

    1. You have access
      EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO
      Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251
  6. Chun, Jin-Ho

    1. You have access
      STEREOSELECTIVE METABOLISM OF LANSOPRAZOLE BY HUMAN LIVER CYTOCHROME P450 ENZYMES
      Kyoung-Ah Kim, Min-Jung Kim, Ji-Young Park, Ji-Hong Shon, Young-Ran Yoon, Sang-Seop Lee, Kwang-Hyeon Liu, Jin-Ho Chun, Myung-Ho Hyun and Jae-Gook Shin
      Drug Metabolism and Disposition October 2003, 31 (10) 1227-1234; DOI: https://doi.org/10.1124/dmd.31.10.1227

D

  1. Dallas, Cham E.

    1. You have access
      PLASMA BINDING OF TRICHLOROACETIC ACID IN MICE, RATS, AND HUMANS UNDER CANCER BIOASSAY AND ENVIRONMENTAL EXPOSURE CONDITIONS
      Michael H. Lumpkin, James V. Bruckner, Jerry L. Campbell, Cham E. Dallas, Catherine A. White and Jeffrey W. Fisher
      Drug Metabolism and Disposition October 2003, 31 (10) 1203-1207; DOI: https://doi.org/10.1124/dmd.31.10.1203
  2. Dalvie, Deepak K.

    1. You have access
      IN VITRO METABOLISM STUDIES ON THE ISOXAZOLE RING SCISSION IN THE ANTI-INFLAMMATORY AGENT LEFLUNOMIDE TO ITS ACTIVE α-CYANOENOL METABOLITE A771726: MECHANISTIC SIMILARITIES WITH THE CYTOCHROME P450-CATALYZED DEHYDRATION OF ALDOXIMES
      Amit S. Kalgutkar, Hang T. Nguyen, Alfin D. N. Vaz, Anke Doan, Deepak K. Dalvie, Dale G. McLeod and John C. Murray
      Drug Metabolism and Disposition October 2003, 31 (10) 1240-1250; DOI: https://doi.org/10.1124/dmd.31.10.1240
  3. Ding, Xinxin

    1. You have access
      COMPARATIVE METABOLISM OF THE TOBACCO-SPECIFIC NITROSAMINES 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE AND 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL BY RAT CYTOCHROME P450 2A3 AND HUMAN CYTOCHROME P450 2A13
      John R. Jalas, Xinxin Ding and Sharon E. Murphy
      Drug Metabolism and Disposition October 2003, 31 (10) 1199-1202; DOI: https://doi.org/10.1124/dmd.31.10.1199
  4. Doan, Anke

    1. You have access
      IN VITRO METABOLISM STUDIES ON THE ISOXAZOLE RING SCISSION IN THE ANTI-INFLAMMATORY AGENT LEFLUNOMIDE TO ITS ACTIVE α-CYANOENOL METABOLITE A771726: MECHANISTIC SIMILARITIES WITH THE CYTOCHROME P450-CATALYZED DEHYDRATION OF ALDOXIMES
      Amit S. Kalgutkar, Hang T. Nguyen, Alfin D. N. Vaz, Anke Doan, Deepak K. Dalvie, Dale G. McLeod and John C. Murray
      Drug Metabolism and Disposition October 2003, 31 (10) 1240-1250; DOI: https://doi.org/10.1124/dmd.31.10.1240

F

  1. Fisher, Jeffrey W.

    1. You have access
      PLASMA BINDING OF TRICHLOROACETIC ACID IN MICE, RATS, AND HUMANS UNDER CANCER BIOASSAY AND ENVIRONMENTAL EXPOSURE CONDITIONS
      Michael H. Lumpkin, James V. Bruckner, Jerry L. Campbell, Cham E. Dallas, Catherine A. White and Jeffrey W. Fisher
      Drug Metabolism and Disposition October 2003, 31 (10) 1203-1207; DOI: https://doi.org/10.1124/dmd.31.10.1203
  2. Fujino, Naoko

    1. You have access
      EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO
      Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251
  3. Fukami, Takehiro

    1. You have access
      EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO
      Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251

H

  1. Hata, Mikiko

    1. You have access
      EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO
      Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251
  2. He, Nan

    1. You have access
      PHARMACOKINETICS OF CITALOPRAM IN RELATION TO GENETIC POLYMORPHISM OF CYP2C19
      Bang-Ning Yu, Guo-Lin Chen, Nan He, Dong-Sheng Ouyang, Xiao-Ping Chen, Zhao-Qian Liu and Hong-Hao Zhou
      Drug Metabolism and Disposition October 2003, 31 (10) 1255-1259; DOI: https://doi.org/10.1124/dmd.31.10.1255
  3. Horibe, Sayo

    1. You have access
      EXPRESSION PROFILES OF DRUG-METABOLIZING ENZYME CYP3A AND DRUG EFFLUX TRANSPORTER MULTIDRUG RESISTANCE 1 SUBFAMILY mRNAS IN RAT SMALL INTESTINE
      Kohji Takara, Noriaki Ohnishi, Sayo Horibe and Teruyoshi Yokoyama
      Drug Metabolism and Disposition October 2003, 31 (10) 1235-1239; DOI: https://doi.org/10.1124/dmd.31.10.1235
  4. Hyun, Myung-Ho

    1. You have access
      STEREOSELECTIVE METABOLISM OF LANSOPRAZOLE BY HUMAN LIVER CYTOCHROME P450 ENZYMES
      Kyoung-Ah Kim, Min-Jung Kim, Ji-Young Park, Ji-Hong Shon, Young-Ran Yoon, Sang-Seop Lee, Kwang-Hyeon Liu, Jin-Ho Chun, Myung-Ho Hyun and Jae-Gook Shin
      Drug Metabolism and Disposition October 2003, 31 (10) 1227-1234; DOI: https://doi.org/10.1124/dmd.31.10.1227

I

  1. Ishii, Yasuyuki

    1. You have access
      EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO
      Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251

J

  1. Jalas, John R.

    1. You have access
      COMPARATIVE METABOLISM OF THE TOBACCO-SPECIFIC NITROSAMINES 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE AND 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL BY RAT CYTOCHROME P450 2A3 AND HUMAN CYTOCHROME P450 2A13
      John R. Jalas, Xinxin Ding and Sharon E. Murphy
      Drug Metabolism and Disposition October 2003, 31 (10) 1199-1202; DOI: https://doi.org/10.1124/dmd.31.10.1199

K

  1. Kalgutkar, Amit S.

    1. You have access
      IN VITRO METABOLISM STUDIES ON THE ISOXAZOLE RING SCISSION IN THE ANTI-INFLAMMATORY AGENT LEFLUNOMIDE TO ITS ACTIVE α-CYANOENOL METABOLITE A771726: MECHANISTIC SIMILARITIES WITH THE CYTOCHROME P450-CATALYZED DEHYDRATION OF ALDOXIMES
      Amit S. Kalgutkar, Hang T. Nguyen, Alfin D. N. Vaz, Anke Doan, Deepak K. Dalvie, Dale G. McLeod and John C. Murray
      Drug Metabolism and Disposition October 2003, 31 (10) 1240-1250; DOI: https://doi.org/10.1124/dmd.31.10.1240
  2. Kanatani, Akio

    1. You have access
      EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO
      Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251
  3. Kim, Kyoung-Ah

    1. You have access
      STEREOSELECTIVE METABOLISM OF LANSOPRAZOLE BY HUMAN LIVER CYTOCHROME P450 ENZYMES
      Kyoung-Ah Kim, Min-Jung Kim, Ji-Young Park, Ji-Hong Shon, Young-Ran Yoon, Sang-Seop Lee, Kwang-Hyeon Liu, Jin-Ho Chun, Myung-Ho Hyun and Jae-Gook Shin
      Drug Metabolism and Disposition October 2003, 31 (10) 1227-1234; DOI: https://doi.org/10.1124/dmd.31.10.1227
  4. Kim, Min-Jung

    1. You have access
      STEREOSELECTIVE METABOLISM OF LANSOPRAZOLE BY HUMAN LIVER CYTOCHROME P450 ENZYMES
      Kyoung-Ah Kim, Min-Jung Kim, Ji-Young Park, Ji-Hong Shon, Young-Ran Yoon, Sang-Seop Lee, Kwang-Hyeon Liu, Jin-Ho Chun, Myung-Ho Hyun and Jae-Gook Shin
      Drug Metabolism and Disposition October 2003, 31 (10) 1227-1234; DOI: https://doi.org/10.1124/dmd.31.10.1227
  5. Kim, Sang G.

    1. You have access
      INSULIN AND GLUCAGON SIGNALING IN REGULATION OF MICROSOMAL EPOXIDE HYDROLASE EXPRESSION IN PRIMARY CULTURED RAT HEPATOCYTES
      Sang K. Kim, Kimberley J. Woodcroft, Sang G. Kim and Raymond F. Novak
      Drug Metabolism and Disposition October 2003, 31 (10) 1260-1268; DOI: https://doi.org/10.1124/dmd.31.10.1260
  6. Kim, Sang K.

    1. You have access
      INSULIN AND GLUCAGON SIGNALING IN REGULATION OF MICROSOMAL EPOXIDE HYDROLASE EXPRESSION IN PRIMARY CULTURED RAT HEPATOCYTES
      Sang K. Kim, Kimberley J. Woodcroft, Sang G. Kim and Raymond F. Novak
      Drug Metabolism and Disposition October 2003, 31 (10) 1260-1268; DOI: https://doi.org/10.1124/dmd.31.10.1260
  7. Kochansky, Christopher

    1. You have access
      METABOLISM AND PHARMACOKINETICS OF A DIPEPTIDYL PEPTIDASE IV INHIBITOR IN RATS, DOGS, AND MONKEYS WITH SELECTIVE CARBAMOYL GLUCURONIDATION OF THE PRIMARY AMINE IN DOGS
      Maria G. Beconi, Ann Mao, David Q. Liu, Christopher Kochansky, Tony Pereira, Conrad Raab, Paul Pearson and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition October 2003, 31 (10) 1269-1277; DOI: https://doi.org/10.1124/dmd.31.10.1269

L

  1. Lebetkin, E. H.

    1. You have access
      METABOLISM OF (R)-(+)-MENTHOFURAN IN FISCHER-344 RATS: IDENTIFICATION OF SULFONIC ACID METABOLITES
      L.-J. Chen, E. H. Lebetkin and L. T. Burka
      Drug Metabolism and Disposition October 2003, 31 (10) 1208-1213; DOI: https://doi.org/10.1124/dmd.31.10.1208
  2. Lee, Sang-Seop

    1. You have access
      STEREOSELECTIVE METABOLISM OF LANSOPRAZOLE BY HUMAN LIVER CYTOCHROME P450 ENZYMES
      Kyoung-Ah Kim, Min-Jung Kim, Ji-Young Park, Ji-Hong Shon, Young-Ran Yoon, Sang-Seop Lee, Kwang-Hyeon Liu, Jin-Ho Chun, Myung-Ho Hyun and Jae-Gook Shin
      Drug Metabolism and Disposition October 2003, 31 (10) 1227-1234; DOI: https://doi.org/10.1124/dmd.31.10.1227
  3. Lee Chiu, Shuet-Hing

    1. You have access
      METABOLISM AND PHARMACOKINETICS OF A DIPEPTIDYL PEPTIDASE IV INHIBITOR IN RATS, DOGS, AND MONKEYS WITH SELECTIVE CARBAMOYL GLUCURONIDATION OF THE PRIMARY AMINE IN DOGS
      Maria G. Beconi, Ann Mao, David Q. Liu, Christopher Kochansky, Tony Pereira, Conrad Raab, Paul Pearson and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition October 2003, 31 (10) 1269-1277; DOI: https://doi.org/10.1124/dmd.31.10.1269
  4. Liu, David Q.

    1. You have access
      METABOLISM AND PHARMACOKINETICS OF A DIPEPTIDYL PEPTIDASE IV INHIBITOR IN RATS, DOGS, AND MONKEYS WITH SELECTIVE CARBAMOYL GLUCURONIDATION OF THE PRIMARY AMINE IN DOGS
      Maria G. Beconi, Ann Mao, David Q. Liu, Christopher Kochansky, Tony Pereira, Conrad Raab, Paul Pearson and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition October 2003, 31 (10) 1269-1277; DOI: https://doi.org/10.1124/dmd.31.10.1269
  5. Liu, Kwang-Hyeon

    1. You have access
      STEREOSELECTIVE METABOLISM OF LANSOPRAZOLE BY HUMAN LIVER CYTOCHROME P450 ENZYMES
      Kyoung-Ah Kim, Min-Jung Kim, Ji-Young Park, Ji-Hong Shon, Young-Ran Yoon, Sang-Seop Lee, Kwang-Hyeon Liu, Jin-Ho Chun, Myung-Ho Hyun and Jae-Gook Shin
      Drug Metabolism and Disposition October 2003, 31 (10) 1227-1234; DOI: https://doi.org/10.1124/dmd.31.10.1227
  6. Liu, Zhao-Qian

    1. You have access
      PHARMACOKINETICS OF CITALOPRAM IN RELATION TO GENETIC POLYMORPHISM OF CYP2C19
      Bang-Ning Yu, Guo-Lin Chen, Nan He, Dong-Sheng Ouyang, Xiao-Ping Chen, Zhao-Qian Liu and Hong-Hao Zhou
      Drug Metabolism and Disposition October 2003, 31 (10) 1255-1259; DOI: https://doi.org/10.1124/dmd.31.10.1255
  7. Lumpkin, Michael H.

    1. You have access
      PLASMA BINDING OF TRICHLOROACETIC ACID IN MICE, RATS, AND HUMANS UNDER CANCER BIOASSAY AND ENVIRONMENTAL EXPOSURE CONDITIONS
      Michael H. Lumpkin, James V. Bruckner, Jerry L. Campbell, Cham E. Dallas, Catherine A. White and Jeffrey W. Fisher
      Drug Metabolism and Disposition October 2003, 31 (10) 1203-1207; DOI: https://doi.org/10.1124/dmd.31.10.1203

M

  1. Mao, Ann

    1. You have access
      METABOLISM AND PHARMACOKINETICS OF A DIPEPTIDYL PEPTIDASE IV INHIBITOR IN RATS, DOGS, AND MONKEYS WITH SELECTIVE CARBAMOYL GLUCURONIDATION OF THE PRIMARY AMINE IN DOGS
      Maria G. Beconi, Ann Mao, David Q. Liu, Christopher Kochansky, Tony Pereira, Conrad Raab, Paul Pearson and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition October 2003, 31 (10) 1269-1277; DOI: https://doi.org/10.1124/dmd.31.10.1269
  2. McLeod, Dale G.

    1. You have access
      IN VITRO METABOLISM STUDIES ON THE ISOXAZOLE RING SCISSION IN THE ANTI-INFLAMMATORY AGENT LEFLUNOMIDE TO ITS ACTIVE α-CYANOENOL METABOLITE A771726: MECHANISTIC SIMILARITIES WITH THE CYTOCHROME P450-CATALYZED DEHYDRATION OF ALDOXIMES
      Amit S. Kalgutkar, Hang T. Nguyen, Alfin D. N. Vaz, Anke Doan, Deepak K. Dalvie, Dale G. McLeod and John C. Murray
      Drug Metabolism and Disposition October 2003, 31 (10) 1240-1250; DOI: https://doi.org/10.1124/dmd.31.10.1240
  3. Murphy, Sharon E.

    1. You have access
      COMPARATIVE METABOLISM OF THE TOBACCO-SPECIFIC NITROSAMINES 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE AND 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL BY RAT CYTOCHROME P450 2A3 AND HUMAN CYTOCHROME P450 2A13
      John R. Jalas, Xinxin Ding and Sharon E. Murphy
      Drug Metabolism and Disposition October 2003, 31 (10) 1199-1202; DOI: https://doi.org/10.1124/dmd.31.10.1199
  4. Murray, John C.

    1. You have access
      IN VITRO METABOLISM STUDIES ON THE ISOXAZOLE RING SCISSION IN THE ANTI-INFLAMMATORY AGENT LEFLUNOMIDE TO ITS ACTIVE α-CYANOENOL METABOLITE A771726: MECHANISTIC SIMILARITIES WITH THE CYTOCHROME P450-CATALYZED DEHYDRATION OF ALDOXIMES
      Amit S. Kalgutkar, Hang T. Nguyen, Alfin D. N. Vaz, Anke Doan, Deepak K. Dalvie, Dale G. McLeod and John C. Murray
      Drug Metabolism and Disposition October 2003, 31 (10) 1240-1250; DOI: https://doi.org/10.1124/dmd.31.10.1240

N

  1. Nguyen, Hang T.

    1. You have access
      IN VITRO METABOLISM STUDIES ON THE ISOXAZOLE RING SCISSION IN THE ANTI-INFLAMMATORY AGENT LEFLUNOMIDE TO ITS ACTIVE α-CYANOENOL METABOLITE A771726: MECHANISTIC SIMILARITIES WITH THE CYTOCHROME P450-CATALYZED DEHYDRATION OF ALDOXIMES
      Amit S. Kalgutkar, Hang T. Nguyen, Alfin D. N. Vaz, Anke Doan, Deepak K. Dalvie, Dale G. McLeod and John C. Murray
      Drug Metabolism and Disposition October 2003, 31 (10) 1240-1250; DOI: https://doi.org/10.1124/dmd.31.10.1240
  2. Novak, Raymond F.

    1. You have access
      INSULIN AND GLUCAGON SIGNALING IN REGULATION OF MICROSOMAL EPOXIDE HYDROLASE EXPRESSION IN PRIMARY CULTURED RAT HEPATOCYTES
      Sang K. Kim, Kimberley J. Woodcroft, Sang G. Kim and Raymond F. Novak
      Drug Metabolism and Disposition October 2003, 31 (10) 1260-1268; DOI: https://doi.org/10.1124/dmd.31.10.1260

O

  1. Ohe, Tomoyuki

    1. You have access
      EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO
      Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251
  2. Ohnishi, Noriaki

    1. You have access
      EXPRESSION PROFILES OF DRUG-METABOLIZING ENZYME CYP3A AND DRUG EFFLUX TRANSPORTER MULTIDRUG RESISTANCE 1 SUBFAMILY mRNAS IN RAT SMALL INTESTINE
      Kohji Takara, Noriaki Ohnishi, Sayo Horibe and Teruyoshi Yokoyama
      Drug Metabolism and Disposition October 2003, 31 (10) 1235-1239; DOI: https://doi.org/10.1124/dmd.31.10.1235
  3. Ouyang, Dong-Sheng

    1. You have access
      PHARMACOKINETICS OF CITALOPRAM IN RELATION TO GENETIC POLYMORPHISM OF CYP2C19
      Bang-Ning Yu, Guo-Lin Chen, Nan He, Dong-Sheng Ouyang, Xiao-Ping Chen, Zhao-Qian Liu and Hong-Hao Zhou
      Drug Metabolism and Disposition October 2003, 31 (10) 1255-1259; DOI: https://doi.org/10.1124/dmd.31.10.1255

P

  1. Pang, K. Sandy

    1. You have access
      INFLUENCE OF P-GLYCOPROTEIN, TRANSFER CLEARANCES, AND DRUG BINDING ON INTESTINAL METABOLISM IN CACO-2 CELL MONOLAYERS OR MEMBRANE PREPARATIONS: A THEORETICAL ANALYSIS
      Debbie Tam, Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition October 2003, 31 (10) 1214-1226; DOI: https://doi.org/10.1124/dmd.31.10.1214
  2. Park, Ji-Young

    1. You have access
      STEREOSELECTIVE METABOLISM OF LANSOPRAZOLE BY HUMAN LIVER CYTOCHROME P450 ENZYMES
      Kyoung-Ah Kim, Min-Jung Kim, Ji-Young Park, Ji-Hong Shon, Young-Ran Yoon, Sang-Seop Lee, Kwang-Hyeon Liu, Jin-Ho Chun, Myung-Ho Hyun and Jae-Gook Shin
      Drug Metabolism and Disposition October 2003, 31 (10) 1227-1234; DOI: https://doi.org/10.1124/dmd.31.10.1227
  3. Pearson, Paul

    1. You have access
      METABOLISM AND PHARMACOKINETICS OF A DIPEPTIDYL PEPTIDASE IV INHIBITOR IN RATS, DOGS, AND MONKEYS WITH SELECTIVE CARBAMOYL GLUCURONIDATION OF THE PRIMARY AMINE IN DOGS
      Maria G. Beconi, Ann Mao, David Q. Liu, Christopher Kochansky, Tony Pereira, Conrad Raab, Paul Pearson and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition October 2003, 31 (10) 1269-1277; DOI: https://doi.org/10.1124/dmd.31.10.1269
  4. Pereira, Tony

    1. You have access
      METABOLISM AND PHARMACOKINETICS OF A DIPEPTIDYL PEPTIDASE IV INHIBITOR IN RATS, DOGS, AND MONKEYS WITH SELECTIVE CARBAMOYL GLUCURONIDATION OF THE PRIMARY AMINE IN DOGS
      Maria G. Beconi, Ann Mao, David Q. Liu, Christopher Kochansky, Tony Pereira, Conrad Raab, Paul Pearson and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition October 2003, 31 (10) 1269-1277; DOI: https://doi.org/10.1124/dmd.31.10.1269

R

  1. Raab, Conrad

    1. You have access
      METABOLISM AND PHARMACOKINETICS OF A DIPEPTIDYL PEPTIDASE IV INHIBITOR IN RATS, DOGS, AND MONKEYS WITH SELECTIVE CARBAMOYL GLUCURONIDATION OF THE PRIMARY AMINE IN DOGS
      Maria G. Beconi, Ann Mao, David Q. Liu, Christopher Kochansky, Tony Pereira, Conrad Raab, Paul Pearson and Shuet-Hing Lee Chiu
      Drug Metabolism and Disposition October 2003, 31 (10) 1269-1277; DOI: https://doi.org/10.1124/dmd.31.10.1269

S

  1. Sato, Masahiko

    1. You have access
      EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO
      Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251
  2. Shibata, Yoshihiro

    1. You have access
      EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO
      Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251
  3. Shin, Jae-Gook

    1. You have access
      STEREOSELECTIVE METABOLISM OF LANSOPRAZOLE BY HUMAN LIVER CYTOCHROME P450 ENZYMES
      Kyoung-Ah Kim, Min-Jung Kim, Ji-Young Park, Ji-Hong Shon, Young-Ran Yoon, Sang-Seop Lee, Kwang-Hyeon Liu, Jin-Ho Chun, Myung-Ho Hyun and Jae-Gook Shin
      Drug Metabolism and Disposition October 2003, 31 (10) 1227-1234; DOI: https://doi.org/10.1124/dmd.31.10.1227
  4. Shon, Ji-Hong

    1. You have access
      STEREOSELECTIVE METABOLISM OF LANSOPRAZOLE BY HUMAN LIVER CYTOCHROME P450 ENZYMES
      Kyoung-Ah Kim, Min-Jung Kim, Ji-Young Park, Ji-Hong Shon, Young-Ran Yoon, Sang-Seop Lee, Kwang-Hyeon Liu, Jin-Ho Chun, Myung-Ho Hyun and Jae-Gook Shin
      Drug Metabolism and Disposition October 2003, 31 (10) 1227-1234; DOI: https://doi.org/10.1124/dmd.31.10.1227
  5. Sun, Huadong

    1. You have access
      INFLUENCE OF P-GLYCOPROTEIN, TRANSFER CLEARANCES, AND DRUG BINDING ON INTESTINAL METABOLISM IN CACO-2 CELL MONOLAYERS OR MEMBRANE PREPARATIONS: A THEORETICAL ANALYSIS
      Debbie Tam, Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition October 2003, 31 (10) 1214-1226; DOI: https://doi.org/10.1124/dmd.31.10.1214

T

  1. Takara, Kohji

    1. You have access
      EXPRESSION PROFILES OF DRUG-METABOLIZING ENZYME CYP3A AND DRUG EFFLUX TRANSPORTER MULTIDRUG RESISTANCE 1 SUBFAMILY mRNAS IN RAT SMALL INTESTINE
      Kohji Takara, Noriaki Ohnishi, Sayo Horibe and Teruyoshi Yokoyama
      Drug Metabolism and Disposition October 2003, 31 (10) 1235-1239; DOI: https://doi.org/10.1124/dmd.31.10.1235
  2. Tam, Debbie

    1. You have access
      INFLUENCE OF P-GLYCOPROTEIN, TRANSFER CLEARANCES, AND DRUG BINDING ON INTESTINAL METABOLISM IN CACO-2 CELL MONOLAYERS OR MEMBRANE PREPARATIONS: A THEORETICAL ANALYSIS
      Debbie Tam, Huadong Sun and K. Sandy Pang
      Drug Metabolism and Disposition October 2003, 31 (10) 1214-1226; DOI: https://doi.org/10.1124/dmd.31.10.1214
  3. Tanaka, Sachiko

    1. You have access
      EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO
      Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251

V

  1. Vaz, Alfin D. N.

    1. You have access
      IN VITRO METABOLISM STUDIES ON THE ISOXAZOLE RING SCISSION IN THE ANTI-INFLAMMATORY AGENT LEFLUNOMIDE TO ITS ACTIVE α-CYANOENOL METABOLITE A771726: MECHANISTIC SIMILARITIES WITH THE CYTOCHROME P450-CATALYZED DEHYDRATION OF ALDOXIMES
      Amit S. Kalgutkar, Hang T. Nguyen, Alfin D. N. Vaz, Anke Doan, Deepak K. Dalvie, Dale G. McLeod and John C. Murray
      Drug Metabolism and Disposition October 2003, 31 (10) 1240-1250; DOI: https://doi.org/10.1124/dmd.31.10.1240

W

  1. White, Catherine A.

    1. You have access
      PLASMA BINDING OF TRICHLOROACETIC ACID IN MICE, RATS, AND HUMANS UNDER CANCER BIOASSAY AND ENVIRONMENTAL EXPOSURE CONDITIONS
      Michael H. Lumpkin, James V. Bruckner, Jerry L. Campbell, Cham E. Dallas, Catherine A. White and Jeffrey W. Fisher
      Drug Metabolism and Disposition October 2003, 31 (10) 1203-1207; DOI: https://doi.org/10.1124/dmd.31.10.1203
  2. Woodcroft, Kimberley J.

    1. You have access
      INSULIN AND GLUCAGON SIGNALING IN REGULATION OF MICROSOMAL EPOXIDE HYDROLASE EXPRESSION IN PRIMARY CULTURED RAT HEPATOCYTES
      Sang K. Kim, Kimberley J. Woodcroft, Sang G. Kim and Raymond F. Novak
      Drug Metabolism and Disposition October 2003, 31 (10) 1260-1268; DOI: https://doi.org/10.1124/dmd.31.10.1260

Y

  1. Yamazaki, Masayo

    1. You have access
      EFFECT OF P-GLYCOPROTEIN-MEDIATED EFFLUX ON CEREBROSPINAL FLUID/PLASMA CONCENTRATION RATIO
      Tomoyuki Ohe, Masahiko Sato, Sachiko Tanaka, Naoko Fujino, Mikiko Hata, Yoshihiro Shibata, Akio Kanatani, Takehiro Fukami, Masayo Yamazaki, Masato Chiba and Yasuyuki Ishii
      Drug Metabolism and Disposition October 2003, 31 (10) 1251-1254; DOI: https://doi.org/10.1124/dmd.31.10.1251
  2. Yokoyama, Teruyoshi

    1. You have access
      EXPRESSION PROFILES OF DRUG-METABOLIZING ENZYME CYP3A AND DRUG EFFLUX TRANSPORTER MULTIDRUG RESISTANCE 1 SUBFAMILY mRNAS IN RAT SMALL INTESTINE
      Kohji Takara, Noriaki Ohnishi, Sayo Horibe and Teruyoshi Yokoyama
      Drug Metabolism and Disposition October 2003, 31 (10) 1235-1239; DOI: https://doi.org/10.1124/dmd.31.10.1235
  3. Yoon, Young-Ran

    1. You have access
      STEREOSELECTIVE METABOLISM OF LANSOPRAZOLE BY HUMAN LIVER CYTOCHROME P450 ENZYMES
      Kyoung-Ah Kim, Min-Jung Kim, Ji-Young Park, Ji-Hong Shon, Young-Ran Yoon, Sang-Seop Lee, Kwang-Hyeon Liu, Jin-Ho Chun, Myung-Ho Hyun and Jae-Gook Shin
      Drug Metabolism and Disposition October 2003, 31 (10) 1227-1234; DOI: https://doi.org/10.1124/dmd.31.10.1227
  4. Yu, Bang-Ning

    1. You have access
      PHARMACOKINETICS OF CITALOPRAM IN RELATION TO GENETIC POLYMORPHISM OF CYP2C19
      Bang-Ning Yu, Guo-Lin Chen, Nan He, Dong-Sheng Ouyang, Xiao-Ping Chen, Zhao-Qian Liu and Hong-Hao Zhou
      Drug Metabolism and Disposition October 2003, 31 (10) 1255-1259; DOI: https://doi.org/10.1124/dmd.31.10.1255

Z

  1. Zhou, Hong-Hao

    1. You have access
      PHARMACOKINETICS OF CITALOPRAM IN RELATION TO GENETIC POLYMORPHISM OF CYP2C19
      Bang-Ning Yu, Guo-Lin Chen, Nan He, Dong-Sheng Ouyang, Xiao-Ping Chen, Zhao-Qian Liu and Hong-Hao Zhou
      Drug Metabolism and Disposition October 2003, 31 (10) 1255-1259; DOI: https://doi.org/10.1124/dmd.31.10.1255
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Drug Metabolism and Disposition: 31 (10)
Drug Metabolism and Disposition
Vol. 31, Issue 10
1 Oct 2003
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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