Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn

Table of Contents

November 01, 2003; Volume 31,Issue 11

Short Communications

  • You have access
    THE JUN N-TERMINAL KINASE INHIBITOR SP600125 IS A LIGAND AND ANTAGONIST OF THE ARYL HYDROCARBON RECEPTOR
    Aby Joiakim, Patricia A. Mathieu, Christine Palermo, Thomas A. Gasiewicz and John J. Reiners
    Drug Metabolism and Disposition November 2003, 31 (11) 1279-1282; DOI: https://doi.org/10.1124/dmd.31.11.1279
  • You have access
    EVIDENCE FOR THE VALIDITY OF CORTISOL 6β-HYDROXYLATION CLEARANCE AS A NEW INDEX FOR IN VIVO CYTOCHROME P450 3A PHENOTYPING IN HUMANS
    Takashi Furuta, Atsushi Suzuki, Chieko Mori, Hiromi Shibasaki, Akitomo Yokokawa and Yasuji Kasuya
    Drug Metabolism and Disposition November 2003, 31 (11) 1283-1287; DOI: https://doi.org/10.1124/dmd.31.11.1283
  • You have access
    THE β-d-GLUCOSIDE AND SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 (SGLT1)-INHIBITOR PHLORIDZIN IS TRANSPORTED BY BOTH SGLT1 AND MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS 1/2
    Thomas Walle and U. Kristina Walle
    Drug Metabolism and Disposition November 2003, 31 (11) 1288-1291; DOI: https://doi.org/10.1124/dmd.31.11.1288
  • You have access
    DISPOSITION OF TACROLIMUS IN ISOLATED PERFUSED RAT LIVER: INFLUENCE OF TROLEANDOMYCIN, CYCLOSPORINE, AND GG918
    Chi-Yuan Wu and Leslie Z. Benet
    Drug Metabolism and Disposition November 2003, 31 (11) 1292-1295; DOI: https://doi.org/10.1124/dmd.31.11.1292
  • You have access
    INDUCTION OF ABCC3 (MRP3) BY PREGNANE X RECEPTOR ACTIVATORS
    Shirley Teng, Veronika Jekerle and Micheline Piquette-Miller
    Drug Metabolism and Disposition November 2003, 31 (11) 1296-1299; DOI: https://doi.org/10.1124/dmd.31.11.1296
  • You have access
    SOLVENT EFFECT ON cDNA-EXPRESSED HUMAN SULFOTRANSFERASE (SULT) ACTIVITIES IN VITRO
    Bennett Ma, Magang Shou and Michael L. Schrag
    Drug Metabolism and Disposition November 2003, 31 (11) 1300-1305; DOI: https://doi.org/10.1124/dmd.31.11.1300
  • You have access
    THE EFFECT OF AGE ON SILDENAFIL BIOTRANSFORMATION IN RAT AND MOUSE LIVER MICROSOMES
    Jill S. Warrington, Lisa L. Von Moltke, Jerold S. Harmatz, Richard I. Shader and David J. Greenblatt
    Drug Metabolism and Disposition November 2003, 31 (11) 1306-1309; DOI: https://doi.org/10.1124/dmd.31.11.1306
  • You have access
    GYKI-47261, A NEW AMPA [2-AMINO-3-(3-HYDROXYMETHYLISOXAZOLE-4-YL)PROPIONIC ACID] ANTAGONIST, IS A CYP2E1 INDUCER
    Viola Tamási, Eszter Hazai, Margareta Porsmyr-Palmertz, Magnus Ingelman-Sundberg, László Vereczkey and Katalin Monostory
    Drug Metabolism and Disposition November 2003, 31 (11) 1310-1314; DOI: https://doi.org/10.1124/dmd.31.11.1310

Articles

  • You have access
    INDUCTION OF MULTIDRUG RESISTANCE PROTEIN 3 (MRP3) IN VIVO IS INDEPENDENT OF CONSTITUTIVE ANDROSTANE RECEPTOR
    Nathan J. Cherrington, Angela L. Slitt, Jonathan M. Maher, Xiao-Xue Zhang, Jun Zhang, Wendong Huang, Yu-Jui Yvonne Wan, David D. Moore and Curtis D. Klaassen
    Drug Metabolism and Disposition November 2003, 31 (11) 1315-1319; DOI: https://doi.org/10.1124/dmd.31.11.1315
  • You have access
    USE OF ANTI-(+)-METHAMPHETAMINE MONOCLONAL ANTIBODY TO SIGNIFICANTLY ALTER (+)-METHAMPHETAMINE AND (+)-AMPHETAMINE DISPOSITION IN RATS
    Elizabeth M. Laurenzana, Kelly A. Byrnes-Blake, Alessandra Milesi-Hallé, W. Brooks Gentry, D. Keith Williams and S. Michael Owens
    Drug Metabolism and Disposition November 2003, 31 (11) 1320-1326; DOI: https://doi.org/10.1124/dmd.31.11.1320
  • You have access
    STUDIES ON THE CHEMICAL REACTIVITY OF DICLOFENAC ACYL GLUCURONIDE WITH GLUTATHIONE: IDENTIFICATION OF DICLOFENAC-S-ACYL-GLUTATHIONE IN RAT BILE
    Mark P. Grillo, Charles G. Knutson, Phillip E. Sanders, Daniel J. Waldon, Fengmei Hua and Joseph A. Ware
    Drug Metabolism and Disposition November 2003, 31 (11) 1327-1336; DOI: https://doi.org/10.1124/dmd.31.11.1327
  • You have access
    CONSTITUTIVE EXPRESSION OF VARIOUS XENOBIOTIC AND ENDOBIOTIC TRANSPORTER mRNAs IN THE CHOROID PLEXUS OF RATS
    Supratim Choudhuri, Nathan J. Cherrington, Ning Li and Curtis D. Klaassen
    Drug Metabolism and Disposition November 2003, 31 (11) 1337-1345; DOI: https://doi.org/10.1124/dmd.31.11.1337
  • You have access
    CHARACTERIZATION OF MOUSE SMALL INTESTINAL CYTOCHROME P450 EXPRESSION
    Qing-Yu Zhang, Debbie Dunbar and Laurence S. Kaminsky
    Drug Metabolism and Disposition November 2003, 31 (11) 1346-1351; DOI: https://doi.org/10.1124/dmd.31.11.1346
  • You have access
    MECHANISM-BASED INHIBITION OF HUMAN LIVER MICROSOMAL CYTOCHROME P450 1A2 BY ZILEUTON, A 5-LIPOXYGENASE INHIBITOR
    Ping Lu, Michael L. Schrag, Donald E. Slaughter, Conrad E. Raab, Magang Shou and A. David Rodrigues
    Drug Metabolism and Disposition November 2003, 31 (11) 1352-1360; DOI: https://doi.org/10.1124/dmd.31.11.1352
  • You have access
    N-GLUCURONIDATION OF NICOTINE AND COTININE BY HUMAN LIVER MICROSOMES AND HETEROLOGOUSLY EXPRESSED UDP-GLUCURONOSYLTRANSFERASES
    Gwendolyn E. Kuehl and Sharon E. Murphy
    Drug Metabolism and Disposition November 2003, 31 (11) 1361-1368; DOI: https://doi.org/10.1124/dmd.31.11.1361
  • You have access
    MECHANISM-BASED INACTIVATION OF HUMAN RECOMBINANT P450 2C9 BY THE NONSTEROIDAL ANTI-INFLAMMATORY DRUG SUPROFEN
    John P. O'Donnell, Deepak K. Dalvie, Amit S. Kalgutkar and R. Scott Obach
    Drug Metabolism and Disposition November 2003, 31 (11) 1369-1377; DOI: https://doi.org/10.1124/dmd.31.11.1369
  • You have access
    TRANSACTIVATION OF GLUCOCORTICOID-INDUCIBLE RAT ARYL SULFOTRANSFERASE (SULT1A1) GENE TRANSCRIPTION
    Hai-Lin Fang, Sarita Shenoy, Zhengbo Duanmu, Thomas A. Kocarek and Melissa Runge-Morris
    Drug Metabolism and Disposition November 2003, 31 (11) 1378-1381; DOI: https://doi.org/10.1124/dmd.31.11.1378
  • You have access
    PRECLINICAL CHARACTERIZATION OF 2-[3-[3-[(5-ETHYL-4′-FLUORO-2-HYDROXY[1,1′-BIPHENYL]-4-YL)OXY]PROPOXY]-2-PROPYLPHENOXY]BENZOIC ACID METABOLISM: IN VITRO SPECIES COMPARISON AND IN VIVO DISPOSITION IN RATS
    E. J. Perkins, J. W. Cramer, N. A. Farid, M. G. Gadberry, D. A. Jackson, E. L. Mattiuz, D. D. O'Bannon, H. J. Weiss, W. J. Wheeler, P. G. Wood and K. C. Cassidy
    Drug Metabolism and Disposition November 2003, 31 (11) 1382-1390; DOI: https://doi.org/10.1124/dmd.31.11.1382
  • You have access
    HUMAN CYTOCHROME P450 INHIBITION AND METABOLIC-INTERMEDIATE COMPLEX FORMATION BY GOLDENSEAL EXTRACT AND ITS METHYLENEDIOXYPHENYL COMPONENTS
    Parnali Chatterjee and Michael R. Franklin
    Drug Metabolism and Disposition November 2003, 31 (11) 1391-1397; DOI: https://doi.org/10.1124/dmd.31.11.1391
  • You have access
    METABOLISM OF ROFECOXIB IN VITRO USING HUMAN LIVER SUBCELLULAR FRACTIONS
    Donald Slaughter, Norihiro Takenaga, Ping Lu, Carol Assang, Deborah J. Walsh, Byron H. Arison, Donghui Cui, Rita A. Halpin, Leslie A. Geer, Kamlesh P. Vyas and Thomas A. Baillie
    Drug Metabolism and Disposition November 2003, 31 (11) 1398-1408; DOI: https://doi.org/10.1124/dmd.31.11.1398
  • You have access
    METABOLISM AND DISPOSITION OF NOVEL DES-FLUORO QUINOLONE GARENOXACIN IN EXPERIMENTAL ANIMALS AND AN INTERSPECIES SCALING OF PHARMACOKINETIC PARAMETERS
    Hiroyoshi Hayakawa, Yoko Fukushima, Hiroshi Kato, Hiroyuki Fukumoto, Takumi Kadota, Hiroyuki Yamamoto, Hiroyuki Kuroiwa, Junko Nishigaki and Akira Tsuji
    Drug Metabolism and Disposition November 2003, 31 (11) 1409-1418; DOI: https://doi.org/10.1124/dmd.31.11.1409
  • You have access
    PHARMACOKINETICS OF A TUMOR NECROSIS FACTOR-α PHOSPHOROTHIOATE 2′-O-(2-METHOXYETHYL) MODIFIED ANTISENSE OLIGONUCLEOTIDE: COMPARISON ACROSS SPECIES
    Richard S. Geary, Rosie Z. Yu, Tanya Watanabe, Scott P. Henry, Greg E. Hardee, Alfred Chappell, John Matson, Henri Sasmor, Len Cummins and Arthur A. Levin
    Drug Metabolism and Disposition November 2003, 31 (11) 1419-1428; DOI: https://doi.org/10.1124/dmd.31.11.1419
  • You have access
    IDENTIFICATION OF ZOMEPIRAC-S-ACYL-GLUTATHIONE IN VITRO IN INCUBATIONS WITH RAT HEPATOCYTES AND IN VIVO IN RAT BILE
    Mark P. Grillo and Fengmei Hua
    Drug Metabolism and Disposition November 2003, 31 (11) 1429-1436; DOI: https://doi.org/10.1124/dmd.31.11.1429
  • You have access
    BIOACTIVATION OF THE 3-AMINO-6-CHLOROPYRAZINONE RING IN A THROMBIN INHIBITOR LEADS TO NOVEL DIHYDRO-IMIDAZOLE AND IMIDAZOLIDINE DERIVATIVES: STRUCTURES AND MECHANISM USING 13C-LABELS, MASS SPECTROMETRY, AND NMR
    Raju Subramanian, Charles C. Lin, Jonathan Z. Ho, Steven M. Pitzenberger, Maria V. Silva-Elipe, Christopher R. Gibson, Matthew P. Braun, Xiao Yu, James L. Yergey and Rominder Singh
    Drug Metabolism and Disposition November 2003, 31 (11) 1437-1447; DOI: https://doi.org/10.1124/dmd.31.11.1437
  • You have access
    PHARMACOKINETICS AND METABOLISM OF [14C]EPLERENONE AFTER ORAL ADMINISTRATION TO HUMANS
    Chyung S. Cook, Loren M. Berry, Roy H. Bible, Jeremy D. Hribar, Elisabeth Hajdu and Norman W. Liu
    Drug Metabolism and Disposition November 2003, 31 (11) 1448-1455; DOI: https://doi.org/10.1124/dmd.31.11.1448

Letter to the Editor

  • You have access
    A METHOD FOR IDENTIFICATION OF INHIBITION MECHANISM AND ESTIMATION OF KI IN IN VITRO ENZYME INHIBITION STUDY
    Wanping Geng
    Drug Metabolism and Disposition November 2003, 31 (11) 1456-1457; DOI: https://doi.org/10.1124/dmd.31.11.1456
Back to top
PreviousNext

In this issue

Drug Metabolism and Disposition: 31 (11)
Drug Metabolism and Disposition
Vol. 31, Issue 11
1 Nov 2003
  • Table of Contents
  • About the Cover
  • Index by author
Sign up for alerts

Jump to

  • Short Communications
  • Articles
  • Letter to the Editor
  • Most Cited
  • Most Read
Loading
  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics