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Research ArticleArticle

MECHANISM-BASED INHIBITION OF HUMAN LIVER MICROSOMAL CYTOCHROME P450 1A2 BY ZILEUTON, A 5-LIPOXYGENASE INHIBITOR

Ping Lu, Michael L. Schrag, Donald E. Slaughter, Conrad E. Raab, Magang Shou and A. David Rodrigues
Drug Metabolism and Disposition November 2003, 31 (11) 1352-1360; DOI: https://doi.org/10.1124/dmd.31.11.1352
Ping Lu
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Michael L. Schrag
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Donald E. Slaughter
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Conrad E. Raab
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Magang Shou
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A. David Rodrigues
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Article Information

vol. 31 no. 11 1352-1360
DOI 
https://doi.org/10.1124/dmd.31.11.1352
PubMed 
14570767

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 13, 2003
  • Accepted August 1, 2003
  • Published online October 21, 2003.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Ping Lu,
  2. Michael L. Schrag,
  3. Donald E. Slaughter,
  4. Conrad E. Raab,
  5. Magang Shou and
  6. A. David Rodrigues
  1. Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania (P.L., M.L.S., D.E.S., M.S., A.D.R.); and Department of Drug Metabolism, Merck Research Laboratories, Rahway, New Jersey (C.E.R.)
  1. Address correspondence to:
    Dr. A. David Rodrigues, Department of Drug Metabolism, WP75A-203, Merck Research Laboratories, West Point PA 19486. E-mail: david_rodrigues{at}merck.com
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Drug Metabolism and Disposition: 31 (11)
Drug Metabolism and Disposition
Vol. 31, Issue 11
1 Nov 2003
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Research ArticleArticle

MECHANISM-BASED INHIBITION OF HUMAN LIVER MICROSOMAL CYTOCHROME P450 1A2 BY ZILEUTON, A 5-LIPOXYGENASE INHIBITOR

Ping Lu, Michael L. Schrag, Donald E. Slaughter, Conrad E. Raab, Magang Shou and A. David Rodrigues
Drug Metabolism and Disposition November 1, 2003, 31 (11) 1352-1360; DOI: https://doi.org/10.1124/dmd.31.11.1352

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Research ArticleArticle

MECHANISM-BASED INHIBITION OF HUMAN LIVER MICROSOMAL CYTOCHROME P450 1A2 BY ZILEUTON, A 5-LIPOXYGENASE INHIBITOR

Ping Lu, Michael L. Schrag, Donald E. Slaughter, Conrad E. Raab, Magang Shou and A. David Rodrigues
Drug Metabolism and Disposition November 1, 2003, 31 (11) 1352-1360; DOI: https://doi.org/10.1124/dmd.31.11.1352
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