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Research ArticleArticle

MECHANISM-BASED INACTIVATION OF HUMAN RECOMBINANT P450 2C9 BY THE NONSTEROIDAL ANTI-INFLAMMATORY DRUG SUPROFEN

John P. O'Donnell, Deepak K. Dalvie, Amit S. Kalgutkar and R. Scott Obach
Drug Metabolism and Disposition November 2003, 31 (11) 1369-1377; DOI: https://doi.org/10.1124/dmd.31.11.1369
John P. O'Donnell
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Deepak K. Dalvie
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Amit S. Kalgutkar
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R. Scott Obach
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Article Information

vol. 31 no. 11 1369-1377
DOI 
https://doi.org/10.1124/dmd.31.11.1369
PubMed 
14570769

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 6, 2003
  • Accepted August 11, 2003
  • Published online October 21, 2003.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. John P. O'Donnell,
  2. Deepak K. Dalvie,
  3. Amit S. Kalgutkar and
  4. R. Scott Obach
  1. Pharmacokinetics, Dynamics, and Metabolism Department, Pfizer Global Research and Development, Groton, Connecticut
  1. Address correspondence to:
    John P. O'Donnell, Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research and Development, Groton, CT 06340. E-mail: odonnelljp{at}groton.pfizer.com
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Drug Metabolism and Disposition: 31 (11)
Drug Metabolism and Disposition
Vol. 31, Issue 11
1 Nov 2003
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Research ArticleArticle

MECHANISM-BASED INACTIVATION OF HUMAN RECOMBINANT P450 2C9 BY THE NONSTEROIDAL ANTI-INFLAMMATORY DRUG SUPROFEN

John P. O'Donnell, Deepak K. Dalvie, Amit S. Kalgutkar and R. Scott Obach
Drug Metabolism and Disposition November 1, 2003, 31 (11) 1369-1377; DOI: https://doi.org/10.1124/dmd.31.11.1369

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Research ArticleArticle

MECHANISM-BASED INACTIVATION OF HUMAN RECOMBINANT P450 2C9 BY THE NONSTEROIDAL ANTI-INFLAMMATORY DRUG SUPROFEN

John P. O'Donnell, Deepak K. Dalvie, Amit S. Kalgutkar and R. Scott Obach
Drug Metabolism and Disposition November 1, 2003, 31 (11) 1369-1377; DOI: https://doi.org/10.1124/dmd.31.11.1369
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