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PHARMACOKINETICS OF A TUMOR NECROSIS FACTOR-α PHOSPHOROTHIOATE 2′-O-(2-METHOXYETHYL) MODIFIED ANTISENSE OLIGONUCLEOTIDE: COMPARISON ACROSS SPECIES

Richard S. Geary, Rosie Z. Yu, Tanya Watanabe, Scott P. Henry, Greg E. Hardee, Alfred Chappell, John Matson, Henri Sasmor, Len Cummins and Arthur A. Levin
Drug Metabolism and Disposition November 2003, 31 (11) 1419-1428; DOI: https://doi.org/10.1124/dmd.31.11.1419

Article Information

vol. 31 no. 11 1419-1428
DOI 
https://doi.org/10.1124/dmd.31.11.1419
PubMed 
14570775
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 12, 2003
  • Accepted August 19, 2003
  • Published online October 21, 2003.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Richard S. Geary,
  2. Rosie Z. Yu,
  3. Tanya Watanabe,
  4. Scott P. Henry,
  5. Greg E. Hardee,
  6. Alfred Chappell,
  7. John Matson,
  8. Henri Sasmor,
  9. Len Cummins and
  10. Arthur A. Levin
  1. Isis Pharmaceuticals, Carlsbad, California
  1. Address correspondence to:
    Dr. Richard S. Geary, Isis Pharmaceuticals, Inc., 2292 Faraday Avenue, Carlsbad, CA 92008. E-mail: rgeary{at}isisph.com
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Research ArticleArticle

PHARMACOKINETICS OF A TUMOR NECROSIS FACTOR-α PHOSPHOROTHIOATE 2′-O-(2-METHOXYETHYL) MODIFIED ANTISENSE OLIGONUCLEOTIDE: COMPARISON ACROSS SPECIES

Richard S. Geary, Rosie Z. Yu, Tanya Watanabe, Scott P. Henry, Greg E. Hardee, Alfred Chappell, John Matson, Henri Sasmor, Len Cummins and Arthur A. Levin
Drug Metabolism and Disposition November 1, 2003, 31 (11) 1419-1428; DOI: https://doi.org/10.1124/dmd.31.11.1419
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