Table of Contents

Articles

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  Molecular Modeling and Metabolic Studies of The Interaction of Catechol-O-Methyltransferase and a New Nitrocatechol Inhibitor

  P. N. Palma, M. J. Bonifácio, A. I. Loureiro, L. C. Wright, D. A. Learmonth and P. Soares-da-Silva

  Drug Metabolism and Disposition March 2003, 31 (3) 250-258; DOI: https://doi.org/10.1124/dmd.31.3.250
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  CYP1A1 and CYP1B1 in Blood-Brain Interfaces: CYP1A1-Dependent Bioactivation of 7,12-Dimethylbenz(a)anthracene in Endothelial Cells

  Lizette Granberg, Anna Östergren, Ingvar Brandt and Eva B. Brittebo

  Drug Metabolism and Disposition March 2003, 31 (3) 259-265; DOI: https://doi.org/10.1124/dmd.31.3.259
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  Metabolism of Chloroform in the Human Liver and Identification of the Competent P450s

  Simonetta Gemma, Luciano Vittozzi and Emanuela Testai

  Drug Metabolism and Disposition March 2003, 31 (3) 266-274; DOI: https://doi.org/10.1124/dmd.31.3.266
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  Oxidative Metabolism of Amprenavir in the Human Liver. Effect of the CYP3A Maturation

  J. M. Tréluyer, G. Bowers, N. Cazali, M. Sonnier, E. Rey, G. Pons and T. Cresteil

  Drug Metabolism and Disposition March 2003, 31 (3) 275-281; DOI: https://doi.org/10.1124/dmd.31.3.275
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  Induction of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices

  Robert J. Edwards, Roger J. Price, Patricia S. Watts, Anthony B. Renwick, J. Michael Tredger, Alan R. Boobis and Brian G. Lake

  Drug Metabolism and Disposition March 2003, 31 (3) 282-288; DOI: https://doi.org/10.1124/dmd.31.3.282
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  Apparent Mechanism-based Inhibition of Human CYP2D6 in Vitro by Paroxetine: Comparison with Fluoxetine and Quinidine

  Kirk M. Bertelsen, Karthik Venkatakrishnan, Lisa L. von Moltke, R. Scott Obach and David J. Greenblatt

  Drug Metabolism and Disposition March 2003, 31 (3) 289-293; DOI: https://doi.org/10.1124/dmd.31.3.289
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  Absorption, Distribution, Metabolism, and Excretion of Ximelagatran, an Oral Direct Thrombin Inhibitor, in Rats, Dogs, and Humans

  Ulf G. Eriksson, Ulf Bredberg, Kurt-Jürgen Hoffmann, Anneli Thuresson, Margareth Gabrielsson, Hans Ericsson, Martin Ahnoff, Kristina Gislén, Gunnar Fager and David Gustafsson

  Drug Metabolism and Disposition March 2003, 31 (3) 294-305; DOI: https://doi.org/10.1124/dmd.31.3.294
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  Identification of Trichloroethylene and Its Metabolites in Human Seminal Fluid of Workers Exposed to Trichloroethylene

  Poh-Gek Forkert, Lawrence Lash, Robert Tardif, Nongnuj Tanphaichitr, Catherine Vandevoort and Madeleine Moussa

  Drug Metabolism and Disposition March 2003, 31 (3) 306-311; DOI: https://doi.org/10.1124/dmd.31.3.306
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  P-Glycoprotein Limits the Brain Penetration of Nonsedating but not Sedating H1-Antagonists

  Cuiping Chen, Elizabeth Hanson, John W. Watson and Jae S. Lee

  Drug Metabolism and Disposition March 2003, 31 (3) 312-318; DOI: https://doi.org/10.1124/dmd.31.3.312
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  Effect of Efflux Inhibition on Brain Uptake of Itraconazole in Mice Infected with Cryptococcus neoformans

  Frédéric Imbert, Méryam Jardin, Christine Fernandez, Jean Charles Gantier, Françoise Dromer, Gabriel Baron, France Mentre, Ludy van Beijsterveldt, Eric Singlas and François Gimenez

  Drug Metabolism and Disposition March 2003, 31 (3) 319-325; DOI: https://doi.org/10.1124/dmd.31.3.319
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  Tissue mRNA Expression of the Rat UDP-Glucuronosyltransferase Gene Family

  M. K. Shelby, N. J. Cherrington, N. R. Vansell and C. D. Klaassen

  Drug Metabolism and Disposition March 2003, 31 (3) 326-333; DOI: https://doi.org/10.1124/dmd.31.3.326
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  Metabolism and Disposition of the Antihypertensive Agent Moxonidine in Humans

  Minxia M. He, Trent L. Abraham, Thomas J. Lindsay, Hans C. Schaefer, Isabelle J. Pouliquen, Chris Payne, Boris Czeskis, Lisa A. Shipley, Stuart D. Oliver and Malcolm I. Mitchell

  Drug Metabolism and Disposition March 2003, 31 (3) 334-342; DOI: https://doi.org/10.1124/dmd.31.3.334