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Research ArticleArticle

CYP1A1 and CYP1B1 in Blood-Brain Interfaces: CYP1A1-Dependent Bioactivation of 7,12-Dimethylbenz(a)anthracene in Endothelial Cells

Lizette Granberg, Anna Östergren, Ingvar Brandt and Eva B. Brittebo
Drug Metabolism and Disposition March 2003, 31 (3) 259-265; DOI: https://doi.org/10.1124/dmd.31.3.259

Article Information

vol. 31 no. 3 259-265
DOI 
https://doi.org/10.1124/dmd.31.3.259
PubMed 
12584151
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 25, 2002
  • Accepted November 22, 2002
  • Published online March 1, 2003.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Lizette Granberg1,1,
  2. Anna Östergren2,
  3. Ingvar Brandt1 and
  4. Eva B. Brittebo2
  1. 1Department of Environmental Toxicology, Evolutionary Biology Center, Uppsala University, Uppsala, Sweden (L.G., I.B.); 2Department of Pharmaceutical Biosciences, Biomedical Center, Uppsala University, Uppsala, Sweden (A.Ö., E.B.B.)
  1. Dr. Ingvar Brandt, Dept. of Environmental Toxicology, Evolutionary Biology Center, Norbyvägen 18A, SE-752 36 Uppsala, Sweden. E-mail: IngvarBrandt{at}ebc.uu.se
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Research ArticleArticle

CYP1A1 and CYP1B1 in Blood-Brain Interfaces: CYP1A1-Dependent Bioactivation of 7,12-Dimethylbenz(a)anthracene in Endothelial Cells

Lizette Granberg, Anna Östergren, Ingvar Brandt and Eva B. Brittebo
Drug Metabolism and Disposition March 1, 2003, 31 (3) 259-265; DOI: https://doi.org/10.1124/dmd.31.3.259
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