Table of Contents

Articles

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  Xanthine Oxidase-Catalyzed Metabolism of 2-Nitrofluorene, a Carcinogenic Air Pollutant, in Rat Skin

  Osamu Ueda, Shigeyuki Kitamura, Koji Ohashi, Kazumi Sugihara and Shigeru Ohta

  Drug Metabolism and Disposition April 2003, 31 (4) 367-372; DOI: https://doi.org/10.1124/dmd.31.4.367
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  Segmental Intestinal Transporters and Metabolic Enzymes on Intestinal Drug Absorption

  Debbie Tam, Rommel G. Tirona and K. Sandy Pang

  Drug Metabolism and Disposition April 2003, 31 (4) 373-383; DOI: https://doi.org/10.1124/dmd.31.4.373
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  Inhibition and Activation of the Human Liver Microsomal and Human Cytochrome P450 3A4 Metabolism of Testosterone by Deployment-Related Chemicals

  Khawja A. Usmani, Randy L. Rose and Ernest Hodgson

  Drug Metabolism and Disposition April 2003, 31 (4) 384-391; DOI: https://doi.org/10.1124/dmd.31.4.384
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  Lipopolysaccharide-Mediated Modulation of Cytochromes P450 in Stat1 Null Mice

  Jinmei Pan, Qian Xiang, Simon Ball, JoAnn Scatina, John Kao and Jun-Yan Hong

  Drug Metabolism and Disposition April 2003, 31 (4) 392-397; DOI: https://doi.org/10.1124/dmd.31.4.392
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  Functional Characterization of Cytochrome P450 2B6 Allelic Variants

  Hideto Jinno, Toshiko Tanaka-Kagawa, Akiko Ohno, Yuko Makino, Erika Matsushima, Nobumitsu Hanioka and Masanori Ando

  Drug Metabolism and Disposition April 2003, 31 (4) 398-403; DOI: https://doi.org/10.1124/dmd.31.4.398
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  Identification of the Human Liver Enzymes Involved in the Metabolism of the Antimigraine Agent Almotriptan

  Miquel Salva, Josep M. Jansat, Antonio Martinez-Tobed and Jose M. Palacios

  Drug Metabolism and Disposition April 2003, 31 (4) 404-411; DOI: https://doi.org/10.1124/dmd.31.4.404
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  Characterization of Substrate Binding to Cytochrome P450 1A1 Using Molecular Modeling and Kinetic Analyses: Case of Residue 382

  Jianguo Liu, Spencer S. Ericksen, Dan Besspiata, Charles W. Fisher and Grazyna D. Szklarz

  Drug Metabolism and Disposition April 2003, 31 (4) 412-420; DOI: https://doi.org/10.1124/dmd.31.4.412
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  Effects of Prototypical Microsomal Enzyme Inducers on Cytochrome P450 Expression in Cultured Human Hepatocytes

  Ajay Madan, Richard A. Graham, Kathleen M. Carroll, Daniel R. Mudra, L. Alayne Burton, Linda A. Krueger, April D. Downey, Maciej Czerwinski, Jameson Forster, Maria D. Ribadeneira, Liang-Shang Gan, Edward L. LeCluyse, Karl Zech, Philmore Robertson, Patrick Koch, Lida Antonian, Greg Wagner, Li Yu and Andrew Parkinson

  Drug Metabolism and Disposition April 2003, 31 (4) 421-431; DOI: https://doi.org/10.1124/dmd.31.4.421
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  CYP3A4 and CYP3A7-Mediated Carbamazepine 10,11-Epoxidation Are Activated by Differential Endogenous Steroids

  Hiroyoshi Nakamura, Nao Torimoto, Itsuko Ishii, Noritaka Ariyoshi, Hiromitsu Nakasa, Shigeru Ohmori and Mitsukazu Kitada

  Drug Metabolism and Disposition April 2003, 31 (4) 432-438; DOI: https://doi.org/10.1124/dmd.31.4.432
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  Comparative Effects of Thiazolidinediones on in Vitro P450 Enzyme Induction and Inhibition

  Jasminder Sahi, Christopher B. Black, Geraldine A. Hamilton, Xianxian Zheng, Summer Jolley, Kelly A. Rose, Darryl Gilbert, Edward L. LeCluyse and Michael W. Sinz

  Drug Metabolism and Disposition April 2003, 31 (4) 439-446; DOI: https://doi.org/10.1124/dmd.31.4.439
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  Retention of Transporter Activities in Cryopreserved, Isolated Rat Hepatocytes

  Robert Houle, Jennifer Raoul, Jean-François Lévesque, K. Sandy Pang, Deborah A. Nicoll-Griffith and Jose M. Silva

  Drug Metabolism and Disposition April 2003, 31 (4) 447-451; DOI: https://doi.org/10.1124/dmd.31.4.447
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  Glucuronides of Tea Catechins: Enzymology of Biosynthesis and Biological Activities

  Hong Lu, Xiaofeng Meng, Chuan Li, Shengmin Sang, Christopher Patten, Shuqun Sheng, Jungil Hong, Naisheng Bai, Bozena Winnik, Chi-Tang Ho and Chung S. Yang

  Drug Metabolism and Disposition April 2003, 31 (4) 452-461; DOI: https://doi.org/10.1124/dmd.31.4.452
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  Modeling the Metabolism of Idarubicin to Idarubicinol in Rat Heart: Effect of Rutin and Phenobarbital

  Wonku Kang and Michael Weiss

  Drug Metabolism and Disposition April 2003, 31 (4) 462-468; DOI: https://doi.org/10.1124/dmd.31.4.462
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  Thalidomide-induced Suppression of Embryo Fibroblast Proliferation Requires CYP1A1-Mediated Activation

  Masaaki Miyata, Etsuko Tamura, Kazuko Motoki, Kiyoshi Nagata and Yasushi Yamazoe

  Drug Metabolism and Disposition April 2003, 31 (4) 469-475; DOI: https://doi.org/10.1124/dmd.31.4.469
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  Cytochrome P450 2C8 and Flavin-containing Monooxygenases are Involved in the Metabolism of Tazarotenic Acid in Humans

  Mayssa Attar, Dahai Dong, Kah-Hiing John Ling and Diane D-S. Tang-Liu

  Drug Metabolism and Disposition April 2003, 31 (4) 476-481; DOI: https://doi.org/10.1124/dmd.31.4.476
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  Multiple Alterations of Canalicular Membrane Transport Activities in Rats with CCl₄-induced Hepatic Injury

  Im-Sook Song, Young-Mi Lee, Suk-Jae Chung and Chang-Koo Shim

  Drug Metabolism and Disposition April 2003, 31 (4) 482-490; DOI: https://doi.org/10.1124/dmd.31.4.482
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  Pharmacokinetics and Metabolism of a COX-2 Inhibitor, Valdecoxib, in Mice

  Ji Y. Zhang, Josh J. Yuan, Yue-Fen Wang, Roy H. Bible and Alan P. Breau

  Drug Metabolism and Disposition April 2003, 31 (4) 491-501; DOI: https://doi.org/10.1124/dmd.31.4.491
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  Pharmacokinetics, Metabolic Stability, and Subcutaneous Bioavailability of a Genetically Engineered Analog of DcR3, FLINT [DcR3(R218Q)], in Cynomolgus Monkeys and Mice

  Victor J. Wroblewski, Christy McCloud, Kelly Davis, Joseph Manetta, Radmila Micanovic and Derrick R. Witcher

  Drug Metabolism and Disposition April 2003, 31 (4) 502-507; DOI: https://doi.org/10.1124/dmd.31.4.502