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Research ArticleArticle

CYP3A4 and CYP3A7-Mediated Carbamazepine 10,11-Epoxidation Are Activated by Differential Endogenous Steroids

Hiroyoshi Nakamura, Nao Torimoto, Itsuko Ishii, Noritaka Ariyoshi, Hiromitsu Nakasa, Shigeru Ohmori and Mitsukazu Kitada
Drug Metabolism and Disposition April 2003, 31 (4) 432-438; DOI: https://doi.org/10.1124/dmd.31.4.432
Hiroyoshi Nakamura
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Nao Torimoto
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Itsuko Ishii
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Noritaka Ariyoshi
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Hiromitsu Nakasa
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Shigeru Ohmori
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Mitsukazu Kitada
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Article Information

vol. 31 no. 4 432-438
DOI 
https://doi.org/10.1124/dmd.31.4.432
PubMed 
12642469

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received November 4, 2002
  • Accepted December 20, 2002
  • Published online April 1, 2003.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Hiroyoshi Nakamura1,1,
  2. Nao Torimoto2,
  3. Itsuko Ishii2,
  4. Noritaka Ariyoshi1,
  5. Hiromitsu Nakasa,
  6. Shigeru Ohmori3 and
  7. Mitsukazu Kitada1
  1. 1Division of Pharmacy, Chiba University Hospital Inohana, Chuo-ku, Chiba, Japan (H.N., N.A., H.N., M.K.); 2Graduate School of Pharmaceutical Science, Chiba University Yayoi-cho, inage-ku, Chiba, Japan (N.T., I.I.); and 3Division of Pharmacy, Shinsyu University Hospital Asahi, Matsumoto, Japan (S.O.)
  1. Hiroyoshi Nakamura, Division of Pharmacy, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, Japan. E-mail: hirokun{at}ho.chiba-u.ac.jp
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Drug Metabolism and Disposition: 31 (4)
Drug Metabolism and Disposition
Vol. 31, Issue 4
1 Apr 2003
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Research ArticleArticle

CYP3A4 and CYP3A7-Mediated Carbamazepine 10,11-Epoxidation Are Activated by Differential Endogenous Steroids

Hiroyoshi Nakamura, Nao Torimoto, Itsuko Ishii, Noritaka Ariyoshi, Hiromitsu Nakasa, Shigeru Ohmori and Mitsukazu Kitada
Drug Metabolism and Disposition April 1, 2003, 31 (4) 432-438; DOI: https://doi.org/10.1124/dmd.31.4.432

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Research ArticleArticle

CYP3A4 and CYP3A7-Mediated Carbamazepine 10,11-Epoxidation Are Activated by Differential Endogenous Steroids

Hiroyoshi Nakamura, Nao Torimoto, Itsuko Ishii, Noritaka Ariyoshi, Hiromitsu Nakasa, Shigeru Ohmori and Mitsukazu Kitada
Drug Metabolism and Disposition April 1, 2003, 31 (4) 432-438; DOI: https://doi.org/10.1124/dmd.31.4.432
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