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Research ArticleArticle

Pharmacokinetics, Metabolic Stability, and Subcutaneous Bioavailability of a Genetically Engineered Analog of DcR3, FLINT [DcR3(R218Q)], in Cynomolgus Monkeys and Mice

Victor J. Wroblewski, Christy McCloud, Kelly Davis, Joseph Manetta, Radmila Micanovic and Derrick R. Witcher
Drug Metabolism and Disposition April 2003, 31 (4) 502-507; DOI: https://doi.org/10.1124/dmd.31.4.502

Article Information

vol. 31 no. 4 502-507
DOI 
https://doi.org/10.1124/dmd.31.4.502
PubMed 
12642478
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received November 4, 2002
  • Accepted January 15, 2003
  • Published online April 1, 2003.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Victor J. Wroblewski1,
  2. Christy McCloud1,
  3. Kelly Davis1,
  4. Joseph Manetta2,
  5. Radmila Micanovic2 and
  6. Derrick R. Witcher2
  1. Departments of 1Drug Disposition Development/Commercialization (V.J.W., C.M., K.D.), and 2Bioresearch Technologies/Proteins (J.M., R.M., D.R.W.), Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana
  1. Victor J. Wroblewski, Ph.D., Department of Drug Disposition Development/Commercialization, Drop code 0720, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285. E-mail: wroblewski_victor{at}lilly.com
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Research ArticleArticle

Pharmacokinetics, Metabolic Stability, and Subcutaneous Bioavailability of a Genetically Engineered Analog of DcR3, FLINT [DcR3(R218Q)], in Cynomolgus Monkeys and Mice

Victor J. Wroblewski, Christy McCloud, Kelly Davis, Joseph Manetta, Radmila Micanovic and Derrick R. Witcher
Drug Metabolism and Disposition April 1, 2003, 31 (4) 502-507; DOI: https://doi.org/10.1124/dmd.31.4.502
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