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Drug Metabolism & Disposition

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Table of Contents

September 01, 2003; Volume 31,Issue 9

Commentary

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    PUBLICATION OF STAND-ALONE SINGLE NUCLEOTIDE POLYMORPHISM (SNP) DISCOVERY DATA
    Ronald N. Hines
    Drug Metabolism and Disposition September 2003, 31 (9) 1073; DOI: https://doi.org/10.1124/dmd.31.9.1073

Short Communications

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    SPURIOUS OBSERVATION OF SPLENIC CYP2B1 EXPRESSION
    Meena R. Sharma, Parameswaran Periandythevar and Bernard H. Shapiro
    Drug Metabolism and Disposition September 2003, 31 (9) 1074-1076; DOI: https://doi.org/10.1124/dmd.31.9.1074
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    GENERATION AND VALIDATION OF RAPID COMPUTATIONAL FILTERS FOR CYP2D6 AND CYP3A4
    Sean Ekins, Jennifer Berbaum and Richard K. Harrison
    Drug Metabolism and Disposition September 2003, 31 (9) 1077-1080; DOI: https://doi.org/10.1124/dmd.31.9.1077
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    SINGLE NUCLEOTIDE POLYMORPHISMS OF THE HUMAN CYP2A13 GENE: EVIDENCE FOR A NULL ALLELE
    Xiuling Zhang, Ying Chen, Yiqin Liu, Xiang Ren, Qing-Yu Zhang, Michele Caggana and Xinxin Ding
    Drug Metabolism and Disposition September 2003, 31 (9) 1081-1085; DOI: https://doi.org/10.1124/dmd.31.9.1081
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    ISOFORM SELECTIVITY AND KINETICS OF MORPHINE 3- AND 6-GLUCURONIDATION BY HUMAN UDP-GLUCURONOSYLTRANSFERASES: EVIDENCE FOR ATYPICAL GLUCURONIDATION KINETICS BY UGT2B7
    Andrew N. Stone, Peter I. Mackenzie, Aleksandra Galetin, J. Brian Houston and John O. Miners
    Drug Metabolism and Disposition September 2003, 31 (9) 1086-1089; DOI: https://doi.org/10.1124/dmd.31.9.1086
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    INHIBITORY EFFECT OF GLYBURIDE ON HUMAN CYTOCHROME P450 ISOFORMS IN HUMAN LIVER MICROSOMES
    Kyoung-Ah Kim and Ji-Young Park
    Drug Metabolism and Disposition September 2003, 31 (9) 1090-1092; DOI: https://doi.org/10.1124/dmd.31.9.1090

Articles

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    COMPARATIVE STUDIES ON THE CYTOCHROME P450-ASSOCIATED METABOLISM AND INTERACTION POTENTIAL OF SELEGILINE BETWEEN HUMAN LIVER-DERIVED IN VITRO SYSTEMS
    Jarmo S. Salonen, Leena Nyman, Alan R. Boobis, Robert J. Edwards, Patricia Watts, Brian G. Lake, Roger J. Price, Anthony B. Renwick, Maria-José Gómez-Lechón, José V. Castell, Magnus Ingelman-Sundberg, Mats Hidestrand, Andre Guillouzo, Laurent Corcos, Peter S. Goldfarb, David F.V. Lewis, Päivi Taavitsainen and Olavi Pelkonen
    Drug Metabolism and Disposition September 2003, 31 (9) 1093-1102; DOI: https://doi.org/10.1124/dmd.31.9.1093
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    ONLY TRUNCATED, NOT COMPLETE CYTOCHROME P450 2D6 RNA TRANSCRIPT AND NO DETECTABLE ENZYME ACTIVITY ARE EXPRESSED IN HUMAN LYMPHOCYTES
    Lisa A. McConnachie, Brian Phillips, Manoj Bajpai, Danny D. Shen and Rodney J. Y. Ho
    Drug Metabolism and Disposition September 2003, 31 (9) 1103-1107; DOI: https://doi.org/10.1124/dmd.31.9.1103
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    MULTISITE KINETIC ANALYSIS OF INTERACTIONS BETWEEN PROTOTYPICAL CYP3A4 SUBGROUP SUBSTRATES: MIDAZOLAM, TESTOSTERONE, AND NIFEDIPINE
    Aleksandra Galetin, Stephen E. Clarke and J. Brian Houston
    Drug Metabolism and Disposition September 2003, 31 (9) 1108-1116; DOI: https://doi.org/10.1124/dmd.31.9.1108
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    GLUCURONIDATION OF ANABOLIC ANDROGENIC STEROIDS BY RECOMBINANT HUMAN UDP-GLUCURONOSYLTRANSFERASES
    Tiia Kuuranne, Mika Kurkela, Mario Thevis, Wilhelm Schänzer, Moshe Finel and Risto Kostiainen
    Drug Metabolism and Disposition September 2003, 31 (9) 1117-1124; DOI: https://doi.org/10.1124/dmd.31.9.1117
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    EVALUATION OF 3′-AZIDO-3′-DEOXYTHYMIDINE, MORPHINE, AND CODEINE AS PROBE SUBSTRATES FOR UDP-GLUCURONOSYLTRANSFERASE 2B7 (UGT2B7) IN HUMAN LIVER MICROSOMES: SPECIFICITY AND INFLUENCE OF THE UGT2B7*2 POLYMORPHISM
    Michael H. Court, Soundarajan Krishnaswamy, Qin Hao, Su X. Duan, Christopher J. Patten, Lisa L. von Moltke and David J. Greenblatt
    Drug Metabolism and Disposition September 2003, 31 (9) 1125-1133; DOI: https://doi.org/10.1124/dmd.31.9.1125
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    BIOTRANSFORMATION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE (NNK) IN PERIPHERAL HUMAN LUNG MICROSOMES
    Graeme B. J. Smith, John R. Bend, Leanne L. Bedard, Ken R. Reid, Dimitri Petsikas and Thomas E. Massey
    Drug Metabolism and Disposition September 2003, 31 (9) 1134-1141; DOI: https://doi.org/10.1124/dmd.31.9.1134
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    METABOLISM, EXCRETION, AND PHARMACOKINETICS OF DULOXETINE IN HEALTHY HUMAN SUBJECTS
    R. J. Lantz, T. A. Gillespie, T. J. Rash, F. Kuo, M. Skinner, H-Y. Kuan and M. P. Knadler
    Drug Metabolism and Disposition September 2003, 31 (9) 1142-1150; DOI: https://doi.org/10.1124/dmd.31.9.1142
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    APPLICATION OF COMPARTMENTAL MODELING TO AN EXAMINATION OF IN VITRO INTESTINAL PERMEABILITY DATA: ASSESSING THE IMPACT OF TISSUE UPTAKE, P-GLYCOPROTEIN, AND CYP3A
    Brendan M. Johnson, William N. Charman and Christopher J. H. Porter
    Drug Metabolism and Disposition September 2003, 31 (9) 1151-1160; DOI: https://doi.org/10.1124/dmd.31.9.1151
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    SUBSTRATE SPECIFICITY AND KINETIC PROPERTIES OF SEVEN HETEROLOGOUSLY EXPRESSED DOG CYTOCHROMES P450
    Magang Shou, Ryan Norcross, Grit Sandig, Ping Lu, Yinghe Li, Yuh Lin, Qin Mei, A. David Rodrigues and Thomas H. Rushmore
    Drug Metabolism and Disposition September 2003, 31 (9) 1161-1169; DOI: https://doi.org/10.1124/dmd.31.9.1161
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    CONCURRENT INDUCTION AND MECHANISM-BASED INACTIVATION OF CYP3A4 BY AN l-VALINAMIDE DERIVATIVE
    Gang Luo, Jianrong Lin, William D. Fiske, Renke Dai, Tian J. Yang, Sean Kim, Michael Sinz, Edward LeCluyse, Eric Solon, James M. Brennan, Irma H. Benedek, Summer Jolley, Darryl Gilbert, Lifei Wang, Frank W. Lee and Liang-Shang Gan
    Drug Metabolism and Disposition September 2003, 31 (9) 1170-1175; DOI: https://doi.org/10.1124/dmd.31.9.1170
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    INDUCTION OF MULTIDRUG RESISTANCE PROTEIN 3 IN RAT LIVER IS ASSOCIATED WITH ALTERED VECTORIAL EXCRETION OF ACETAMINOPHEN METABOLITES
    A. L. Slitt, N. J. Cherrington, J. M. Maher and C. D. Klaassen
    Drug Metabolism and Disposition September 2003, 31 (9) 1176-1186; DOI: https://doi.org/10.1124/dmd.31.9.1176
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    CONJUGATION OF CATECHOLS BY RECOMBINANT HUMAN SULFOTRANSFERASES, UDP-GLUCURONOSYLTRANSFERASES, AND SOLUBLE CATECHOL O-METHYLTRANSFERASE: STRUCTURE-CONJUGATION RELATIONSHIPS AND PREDICTIVE MODELS
    Jyrki Taskinen, Brian T. Ethell, Pia Pihlavisto, Alan M. Hood, Brian Burchell and Michael W. H. Coughtrie
    Drug Metabolism and Disposition September 2003, 31 (9) 1187-1197; DOI: https://doi.org/10.1124/dmd.31.9.1187

Erratum

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    CORRECTION TO “DETECTION OF CARBOXYLIC ACIDS AND INHIBITION OF HIPPURIC ACID FORMATION IN RATS TREATED WITH 3-BUTENE-1,2-DIOL, A MAJOR METABOLITE OF 1,3-BUTADIENE”
    Drug Metabolism and Disposition September 2003, 31 (9) 1198; DOI: https://doi.org/10.1124/dmd.31.9.1198
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Drug Metabolism and Disposition: 31 (9)
Drug Metabolism and Disposition
Vol. 31, Issue 9
1 Sep 2003
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