Table of Contents

Articles

• You have access

  COMPARATIVE STUDIES ON THE CYTOCHROME P450-ASSOCIATED METABOLISM AND INTERACTION POTENTIAL OF SELEGILINE BETWEEN HUMAN LIVER-DERIVED IN VITRO SYSTEMS

  Jarmo S. Salonen, Leena Nyman, Alan R. Boobis, Robert J. Edwards, Patricia Watts, Brian G. Lake, Roger J. Price, Anthony B. Renwick, Maria-José Gómez-Lechón, José V. Castell, Magnus Ingelman-Sundberg, Mats Hidestrand, Andre Guillouzo, Laurent Corcos, Peter S. Goldfarb, David F.V. Lewis, Päivi Taavitsainen and Olavi Pelkonen

  Drug Metabolism and Disposition September 2003, 31 (9) 1093-1102; DOI: https://doi.org/10.1124/dmd.31.9.1093
• You have access

  ONLY TRUNCATED, NOT COMPLETE CYTOCHROME P450 2D6 RNA TRANSCRIPT AND NO DETECTABLE ENZYME ACTIVITY ARE EXPRESSED IN HUMAN LYMPHOCYTES

  Lisa A. McConnachie, Brian Phillips, Manoj Bajpai, Danny D. Shen and Rodney J. Y. Ho

  Drug Metabolism and Disposition September 2003, 31 (9) 1103-1107; DOI: https://doi.org/10.1124/dmd.31.9.1103
• You have access

  MULTISITE KINETIC ANALYSIS OF INTERACTIONS BETWEEN PROTOTYPICAL CYP3A4 SUBGROUP SUBSTRATES: MIDAZOLAM, TESTOSTERONE, AND NIFEDIPINE

  Aleksandra Galetin, Stephen E. Clarke and J. Brian Houston

  Drug Metabolism and Disposition September 2003, 31 (9) 1108-1116; DOI: https://doi.org/10.1124/dmd.31.9.1108
• You have access

  GLUCURONIDATION OF ANABOLIC ANDROGENIC STEROIDS BY RECOMBINANT HUMAN UDP-GLUCURONOSYLTRANSFERASES

  Tiia Kuuranne, Mika Kurkela, Mario Thevis, Wilhelm Schänzer, Moshe Finel and Risto Kostiainen

  Drug Metabolism and Disposition September 2003, 31 (9) 1117-1124; DOI: https://doi.org/10.1124/dmd.31.9.1117
• You have access

  EVALUATION OF 3′-AZIDO-3′-DEOXYTHYMIDINE, MORPHINE, AND CODEINE AS PROBE SUBSTRATES FOR UDP-GLUCURONOSYLTRANSFERASE 2B7 (UGT2B7) IN HUMAN LIVER MICROSOMES: SPECIFICITY AND INFLUENCE OF THE UGT2B7^*2 POLYMORPHISM

  Michael H. Court, Soundarajan Krishnaswamy, Qin Hao, Su X. Duan, Christopher J. Patten, Lisa L. von Moltke and David J. Greenblatt

  Drug Metabolism and Disposition September 2003, 31 (9) 1125-1133; DOI: https://doi.org/10.1124/dmd.31.9.1125
• You have access

  BIOTRANSFORMATION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE (NNK) IN PERIPHERAL HUMAN LUNG MICROSOMES

  Graeme B. J. Smith, John R. Bend, Leanne L. Bedard, Ken R. Reid, Dimitri Petsikas and Thomas E. Massey

  Drug Metabolism and Disposition September 2003, 31 (9) 1134-1141; DOI: https://doi.org/10.1124/dmd.31.9.1134
• You have access

  METABOLISM, EXCRETION, AND PHARMACOKINETICS OF DULOXETINE IN HEALTHY HUMAN SUBJECTS

  R. J. Lantz, T. A. Gillespie, T. J. Rash, F. Kuo, M. Skinner, H-Y. Kuan and M. P. Knadler

  Drug Metabolism and Disposition September 2003, 31 (9) 1142-1150; DOI: https://doi.org/10.1124/dmd.31.9.1142
• You have access

  APPLICATION OF COMPARTMENTAL MODELING TO AN EXAMINATION OF IN VITRO INTESTINAL PERMEABILITY DATA: ASSESSING THE IMPACT OF TISSUE UPTAKE, P-GLYCOPROTEIN, AND CYP3A

  Brendan M. Johnson, William N. Charman and Christopher J. H. Porter

  Drug Metabolism and Disposition September 2003, 31 (9) 1151-1160; DOI: https://doi.org/10.1124/dmd.31.9.1151
• You have access

  SUBSTRATE SPECIFICITY AND KINETIC PROPERTIES OF SEVEN HETEROLOGOUSLY EXPRESSED DOG CYTOCHROMES P450

  Magang Shou, Ryan Norcross, Grit Sandig, Ping Lu, Yinghe Li, Yuh Lin, Qin Mei, A. David Rodrigues and Thomas H. Rushmore

  Drug Metabolism and Disposition September 2003, 31 (9) 1161-1169; DOI: https://doi.org/10.1124/dmd.31.9.1161
• You have access

  CONCURRENT INDUCTION AND MECHANISM-BASED INACTIVATION OF CYP3A4 BY AN l-VALINAMIDE DERIVATIVE

  Gang Luo, Jianrong Lin, William D. Fiske, Renke Dai, Tian J. Yang, Sean Kim, Michael Sinz, Edward LeCluyse, Eric Solon, James M. Brennan, Irma H. Benedek, Summer Jolley, Darryl Gilbert, Lifei Wang, Frank W. Lee and Liang-Shang Gan

  Drug Metabolism and Disposition September 2003, 31 (9) 1170-1175; DOI: https://doi.org/10.1124/dmd.31.9.1170
• You have access

  INDUCTION OF MULTIDRUG RESISTANCE PROTEIN 3 IN RAT LIVER IS ASSOCIATED WITH ALTERED VECTORIAL EXCRETION OF ACETAMINOPHEN METABOLITES

  A. L. Slitt, N. J. Cherrington, J. M. Maher and C. D. Klaassen

  Drug Metabolism and Disposition September 2003, 31 (9) 1176-1186; DOI: https://doi.org/10.1124/dmd.31.9.1176
• You have access

  CONJUGATION OF CATECHOLS BY RECOMBINANT HUMAN SULFOTRANSFERASES, UDP-GLUCURONOSYLTRANSFERASES, AND SOLUBLE CATECHOL O-METHYLTRANSFERASE: STRUCTURE-CONJUGATION RELATIONSHIPS AND PREDICTIVE MODELS

  Jyrki Taskinen, Brian T. Ethell, Pia Pihlavisto, Alan M. Hood, Brian Burchell and Michael W. H. Coughtrie

  Drug Metabolism and Disposition September 2003, 31 (9) 1187-1197; DOI: https://doi.org/10.1124/dmd.31.9.1187