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Index by author

October 01, 2004; Volume 32,Issue 10

A

  1. Aboagye, E. O.

    1. PLASMA PHARMACOKINETICS AND METABOLISM OF THE HISTONE DEACETYLASE INHIBITOR TRICHOSTATIN A AFTER INTRAPERITONEAL ADMINISTRATION TO MICE
      L. Sanderson, G. W. Taylor, E. O. Aboagye, J. P. Alao, J. R. Latigo, R. C. Coombes and D. M. Vigushin
      Drug Metabolism and Disposition October 2004, 32 (10) 1132-1138; DOI: https://doi.org/10.1124/dmd.104.000638

  2. Alao, J. P.

    1. PLASMA PHARMACOKINETICS AND METABOLISM OF THE HISTONE DEACETYLASE INHIBITOR TRICHOSTATIN A AFTER INTRAPERITONEAL ADMINISTRATION TO MICE
      L. Sanderson, G. W. Taylor, E. O. Aboagye, J. P. Alao, J. R. Latigo, R. C. Coombes and D. M. Vigushin
      Drug Metabolism and Disposition October 2004, 32 (10) 1132-1138; DOI: https://doi.org/10.1124/dmd.104.000638

  3. Allen, Kyle

    1. DIFFERENCES IN THE INHIBITION OF CYTOCHROMES P450 3A4 AND 3A5 BY METABOLITE-INHIBITOR COMPLEX-FORMING DRUGS
      Donavon J. McConn, Yvonne S. Lin, Kyle Allen, Kent L. Kunze and Kenneth E. Thummel
      Drug Metabolism and Disposition October 2004, 32 (10) 1083-1091; DOI: https://doi.org/10.1124/dmd.32.10.1083

  4. Allen, Kyle E.

    1. ROLE OF ITRACONAZOLE METABOLITES IN CYP3A4 INHIBITION
      Nina Isoherranen, Kent L. Kunze, Kyle E. Allen, Wendel L. Nelson and Kenneth E. Thummel
      Drug Metabolism and Disposition October 2004, 32 (10) 1121-1131; DOI: https://doi.org/10.1124/dmd.104.000315

B

  1. Balakin, Konstantin V.

    1. QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1111-1120; DOI: https://doi.org/10.1124/dmd.104.000364
    2. KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey V. Skorenko, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1183-1189; DOI: https://doi.org/10.1124/dmd.104.000356

  2. Balani, Suresh K.

    1. EFFECTIVE DOSING REGIMEN OF 1-AMINOBENZOTRIAZOLE FOR INHIBITION OF ANTIPYRINE CLEARANCE IN GUINEA PIGS AND MICE USING SERIAL SAMPLING
      Suresh K. Balani, Ping Li, Joanne Nguyen, Kym Cardoza, Hang Zeng, Dun-Xue Mu, Jing-Tao Wu, Liang-Shang Gan and Frank W. Lee
      Drug Metabolism and Disposition October 2004, 32 (10) 1092-1095; DOI: https://doi.org/10.1124/dmd.104.000349

  3. Biba, Mirlinda

    1. SPECIES DIFFERENTIAL STEREOSELECTIVE OXIDATION OF A METHYLSULFIDE METABOLITE OF MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL)PHENYL]METHYL]BENZAMIDE], A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DUAL AGONIST
      Bindhu V. Karanam, Christopher J. Welch, Vijay G. Reddy, Jennifer Chilenski, Mirlinda Biba and Stella Vincent
      Drug Metabolism and Disposition October 2004, 32 (10) 1061-1068; DOI: https://doi.org/10.1124/dmd.104.000224

  4. Blumberg, Bruce

    1. TOCOTRIENOLS ACTIVATE THE STEROID AND XENOBIOTIC RECEPTOR, SXR, AND SELECTIVELY REGULATE EXPRESSION OF ITS TARGET GENES
      Changcheng Zhou, Michelle M. Tabb, Asal Sadatrafiei, Felix Grün and Bruce Blumberg
      Drug Metabolism and Disposition October 2004, 32 (10) 1075-1082; DOI: https://doi.org/10.1124/dmd.104.000299

  5. Bugrim, Andrey

    1. QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1111-1120; DOI: https://doi.org/10.1124/dmd.104.000364
    2. KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey V. Skorenko, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1183-1189; DOI: https://doi.org/10.1124/dmd.104.000356

C

  1. Cardoza, Kym

    1. EFFECTIVE DOSING REGIMEN OF 1-AMINOBENZOTRIAZOLE FOR INHIBITION OF ANTIPYRINE CLEARANCE IN GUINEA PIGS AND MICE USING SERIAL SAMPLING
      Suresh K. Balani, Ping Li, Joanne Nguyen, Kym Cardoza, Hang Zeng, Dun-Xue Mu, Jing-Tao Wu, Liang-Shang Gan and Frank W. Lee
      Drug Metabolism and Disposition October 2004, 32 (10) 1092-1095; DOI: https://doi.org/10.1124/dmd.104.000349

  2. Chiba, Kan

    1. IDENTIFICATION OF DI-(2-ETHYLHEXYL) PHTHALATE-INDUCED CARBOXYLESTERASE 1 IN C57BL/6 MOUSE LIVER MICROSOMES: PURIFICATION, CDNA CLONING, AND BACULOVIRUS-MEDIATED EXPRESSION
      Tomomi Furihata, Masakiyo Hosokawa, Nao Koyano, Takahiro Nakamura, Tetsuo Satoh and Kan Chiba
      Drug Metabolism and Disposition October 2004, 32 (10) 1170-1177; DOI: https://doi.org/10.1124/dmd.104.000620

  3. Chilenski, Jennifer

    1. SPECIES DIFFERENTIAL STEREOSELECTIVE OXIDATION OF A METHYLSULFIDE METABOLITE OF MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL)PHENYL]METHYL]BENZAMIDE], A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DUAL AGONIST
      Bindhu V. Karanam, Christopher J. Welch, Vijay G. Reddy, Jennifer Chilenski, Mirlinda Biba and Stella Vincent
      Drug Metabolism and Disposition October 2004, 32 (10) 1061-1068; DOI: https://doi.org/10.1124/dmd.104.000224

  4. Coombes, R. C.

    1. PLASMA PHARMACOKINETICS AND METABOLISM OF THE HISTONE DEACETYLASE INHIBITOR TRICHOSTATIN A AFTER INTRAPERITONEAL ADMINISTRATION TO MICE
      L. Sanderson, G. W. Taylor, E. O. Aboagye, J. P. Alao, J. R. Latigo, R. C. Coombes and D. M. Vigushin
      Drug Metabolism and Disposition October 2004, 32 (10) 1132-1138; DOI: https://doi.org/10.1124/dmd.104.000638

  5. Creighton, Mellissa

    1. IDENTIFICATION AND METABOLISM OF A NOVEL DIHYDROHYDROXY-S-GLUTATHIONYL CONJUGATE OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST, MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL) PHENYL]METHYL]BENZAMIDE], IN RATS
      Vijay Bhasker G. Reddy, George A. Doss, Mellissa Creighton, Christopher J. Kochansky, Stella H. Vincent, Ronald B. Franklin and Bindhu V. Karanam
      Drug Metabolism and Disposition October 2004, 32 (10) 1154-1161; DOI: https://doi.org/10.1124/dmd.104.000240

  6. Criss, Anne B.

    1. TWO MAJOR GRAPEFRUIT JUICE COMPONENTS DIFFER IN INTESTINAL CYP3A4 INHIBITION KINETIC AND BINDING PROPERTIES
      Mary F. Paine, Anne B. Criss and Paul B. Watkins
      Drug Metabolism and Disposition October 2004, 32 (10) 1146-1153; DOI: https://doi.org/10.1124/dmd.104.000547

D

  1. Doss, George A.

    1. IDENTIFICATION AND METABOLISM OF A NOVEL DIHYDROHYDROXY-S-GLUTATHIONYL CONJUGATE OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST, MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL) PHENYL]METHYL]BENZAMIDE], IN RATS
      Vijay Bhasker G. Reddy, George A. Doss, Mellissa Creighton, Christopher J. Kochansky, Stella H. Vincent, Ronald B. Franklin and Bindhu V. Karanam
      Drug Metabolism and Disposition October 2004, 32 (10) 1154-1161; DOI: https://doi.org/10.1124/dmd.104.000240

E

  1. Ekins, Sean

    1. QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1111-1120; DOI: https://doi.org/10.1124/dmd.104.000364
    2. KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey V. Skorenko, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1183-1189; DOI: https://doi.org/10.1124/dmd.104.000356

  2. Endo, Yoshio

    1. A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3′-ETHYNYL NUCLEOSIDES
      Daigo Murata, Yoshio Endo, Tohru Obata, Kazuki Sakamoto, Yasuhiro Syouji, Masakazu Kadohira, Akira Matsuda and Takuma Sasaki
      Drug Metabolism and Disposition October 2004, 32 (10) 1178-1182; DOI: https://doi.org/10.1124/dmd.104.000737

  3. Endou, Hitoshi

    1. CHARACTERIZATION OF THE RENAL TUBULAR TRANSPORT OF ZONAMPANEL, A NOVEL α-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID RECEPTOR ANTAGONIST, BY HUMAN ORGANIC ANION TRANSPORTERS
      Tadashi Hashimoto, Shinichi Narikawa, Xiu-Lin Huang, Tsuyoshi Minematsu, Takashi Usui, Hidetaka Kamimura and Hitoshi Endou
      Drug Metabolism and Disposition October 2004, 32 (10) 1096-1102; DOI: https://doi.org/10.1124/dmd.32.10.1096

F

  1. Falany, Charles N.

    1. TRICLOSAN AS A SUBSTRATE AND INHIBITOR OF 3′-PHOSPHOADENOSINE 5′-PHOSPHOSULFATE-SULFOTRANSFERASE AND UDP-GLUCURONOSYL TRANSFERASE IN HUMAN LIVER FRACTIONS
      Li-Quan Wang, Charles N. Falany and Margaret O. James
      Drug Metabolism and Disposition October 2004, 32 (10) 1162-1169; DOI: https://doi.org/10.1124/dmd.104.000273

  2. Franklin, Ronald B.

    1. IDENTIFICATION AND METABOLISM OF A NOVEL DIHYDROHYDROXY-S-GLUTATHIONYL CONJUGATE OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST, MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL) PHENYL]METHYL]BENZAMIDE], IN RATS
      Vijay Bhasker G. Reddy, George A. Doss, Mellissa Creighton, Christopher J. Kochansky, Stella H. Vincent, Ronald B. Franklin and Bindhu V. Karanam
      Drug Metabolism and Disposition October 2004, 32 (10) 1154-1161; DOI: https://doi.org/10.1124/dmd.104.000240

  3. Fukunaga, Naoko

    1. CONSTRUCTION OF EXPRESSION SYSTEM FOR HUMAN α1-ACID GLYCOPROTEIN IN PICHIA PASTORIS AND EVALUATION OF ITS DRUG-BINDING PROPERTIES
      Koji Nishi, Naoko Fukunaga and Masaki Otagiri
      Drug Metabolism and Disposition October 2004, 32 (10) 1069-1074; DOI: https://doi.org/10.1124/dmd.104.000513

  4. Furihata, Tomomi

    1. IDENTIFICATION OF DI-(2-ETHYLHEXYL) PHTHALATE-INDUCED CARBOXYLESTERASE 1 IN C57BL/6 MOUSE LIVER MICROSOMES: PURIFICATION, CDNA CLONING, AND BACULOVIRUS-MEDIATED EXPRESSION
      Tomomi Furihata, Masakiyo Hosokawa, Nao Koyano, Takahiro Nakamura, Tetsuo Satoh and Kan Chiba
      Drug Metabolism and Disposition October 2004, 32 (10) 1170-1177; DOI: https://doi.org/10.1124/dmd.104.000620

G

  1. Gan, Liang-Shang

    1. EFFECTIVE DOSING REGIMEN OF 1-AMINOBENZOTRIAZOLE FOR INHIBITION OF ANTIPYRINE CLEARANCE IN GUINEA PIGS AND MICE USING SERIAL SAMPLING
      Suresh K. Balani, Ping Li, Joanne Nguyen, Kym Cardoza, Hang Zeng, Dun-Xue Mu, Jing-Tao Wu, Liang-Shang Gan and Frank W. Lee
      Drug Metabolism and Disposition October 2004, 32 (10) 1092-1095; DOI: https://doi.org/10.1124/dmd.104.000349

  2. Gerk, Phillip M.

    1. ESTRADIOL 3-GLUCURONIDE IS TRANSPORTED BY THE MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2 BUT DOES NOT ACTIVATE THE ALLOSTERIC SITE BOUND BY ESTRADIOL 17-GLUCURONIDE
      Phillip M. Gerk, Wei Li and Mary Vore
      Drug Metabolism and Disposition October 2004, 32 (10) 1139-1145; DOI: https://doi.org/10.1124/dmd.104.000372

  3. Grün, Felix

    1. TOCOTRIENOLS ACTIVATE THE STEROID AND XENOBIOTIC RECEPTOR, SXR, AND SELECTIVELY REGULATE EXPRESSION OF ITS TARGET GENES
      Changcheng Zhou, Michelle M. Tabb, Asal Sadatrafiei, Felix Grün and Bruce Blumberg
      Drug Metabolism and Disposition October 2004, 32 (10) 1075-1082; DOI: https://doi.org/10.1124/dmd.104.000299

H

  1. Hashimoto, Tadashi

    1. CHARACTERIZATION OF THE RENAL TUBULAR TRANSPORT OF ZONAMPANEL, A NOVEL α-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID RECEPTOR ANTAGONIST, BY HUMAN ORGANIC ANION TRANSPORTERS
      Tadashi Hashimoto, Shinichi Narikawa, Xiu-Lin Huang, Tsuyoshi Minematsu, Takashi Usui, Hidetaka Kamimura and Hitoshi Endou
      Drug Metabolism and Disposition October 2004, 32 (10) 1096-1102; DOI: https://doi.org/10.1124/dmd.32.10.1096

  2. Hosokawa, Masakiyo

    1. IDENTIFICATION OF DI-(2-ETHYLHEXYL) PHTHALATE-INDUCED CARBOXYLESTERASE 1 IN C57BL/6 MOUSE LIVER MICROSOMES: PURIFICATION, CDNA CLONING, AND BACULOVIRUS-MEDIATED EXPRESSION
      Tomomi Furihata, Masakiyo Hosokawa, Nao Koyano, Takahiro Nakamura, Tetsuo Satoh and Kan Chiba
      Drug Metabolism and Disposition October 2004, 32 (10) 1170-1177; DOI: https://doi.org/10.1124/dmd.104.000620

  3. Huang, Xiu-Lin

    1. CHARACTERIZATION OF THE RENAL TUBULAR TRANSPORT OF ZONAMPANEL, A NOVEL α-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID RECEPTOR ANTAGONIST, BY HUMAN ORGANIC ANION TRANSPORTERS
      Tadashi Hashimoto, Shinichi Narikawa, Xiu-Lin Huang, Tsuyoshi Minematsu, Takashi Usui, Hidetaka Kamimura and Hitoshi Endou
      Drug Metabolism and Disposition October 2004, 32 (10) 1096-1102; DOI: https://doi.org/10.1124/dmd.32.10.1096

I

  1. Ishii, Yuji

    1. SIMULTANEOUS EXPRESSION OF GUINEA PIG UDP-GLUCURONOSYLTRANSFERASE 2B21 (UGT2B21) AND 2B22 IN COS-7 CELLS ENHANCES UGT2B21-CATALYZED CHLORAMPHENICOL GLUCURONIDATION
      Yuji Ishii, Aya Miyoshi, Daisuke Maji, Hideyuki Yamada and Kazuta Oguri
      Drug Metabolism and Disposition October 2004, 32 (10) 1057-1060; DOI: https://doi.org/10.1124/dmd.32.10.1057

  2. Isoherranen, Nina

    1. ROLE OF ITRACONAZOLE METABOLITES IN CYP3A4 INHIBITION
      Nina Isoherranen, Kent L. Kunze, Kyle E. Allen, Wendel L. Nelson and Kenneth E. Thummel
      Drug Metabolism and Disposition October 2004, 32 (10) 1121-1131; DOI: https://doi.org/10.1124/dmd.104.000315

  3. Ivanenkov, Yan A.

    1. QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1111-1120; DOI: https://doi.org/10.1124/dmd.104.000364
    2. KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey V. Skorenko, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1183-1189; DOI: https://doi.org/10.1124/dmd.104.000356

  4. Ivashchenko, Andrey A.

    1. QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1111-1120; DOI: https://doi.org/10.1124/dmd.104.000364
    2. KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey V. Skorenko, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1183-1189; DOI: https://doi.org/10.1124/dmd.104.000356

J

  1. James, Margaret O.

    1. TRICLOSAN AS A SUBSTRATE AND INHIBITOR OF 3′-PHOSPHOADENOSINE 5′-PHOSPHOSULFATE-SULFOTRANSFERASE AND UDP-GLUCURONOSYL TRANSFERASE IN HUMAN LIVER FRACTIONS
      Li-Quan Wang, Charles N. Falany and Margaret O. James
      Drug Metabolism and Disposition October 2004, 32 (10) 1162-1169; DOI: https://doi.org/10.1124/dmd.104.000273

K

  1. Kadohira, Masakazu

    1. A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3′-ETHYNYL NUCLEOSIDES
      Daigo Murata, Yoshio Endo, Tohru Obata, Kazuki Sakamoto, Yasuhiro Syouji, Masakazu Kadohira, Akira Matsuda and Takuma Sasaki
      Drug Metabolism and Disposition October 2004, 32 (10) 1178-1182; DOI: https://doi.org/10.1124/dmd.104.000737

  2. Kamimura, Hidetaka

    1. CHARACTERIZATION OF THE RENAL TUBULAR TRANSPORT OF ZONAMPANEL, A NOVEL α-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID RECEPTOR ANTAGONIST, BY HUMAN ORGANIC ANION TRANSPORTERS
      Tadashi Hashimoto, Shinichi Narikawa, Xiu-Lin Huang, Tsuyoshi Minematsu, Takashi Usui, Hidetaka Kamimura and Hitoshi Endou
      Drug Metabolism and Disposition October 2004, 32 (10) 1096-1102; DOI: https://doi.org/10.1124/dmd.32.10.1096

  3. Karanam, Bindhu V.

    1. SPECIES DIFFERENTIAL STEREOSELECTIVE OXIDATION OF A METHYLSULFIDE METABOLITE OF MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL)PHENYL]METHYL]BENZAMIDE], A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DUAL AGONIST
      Bindhu V. Karanam, Christopher J. Welch, Vijay G. Reddy, Jennifer Chilenski, Mirlinda Biba and Stella Vincent
      Drug Metabolism and Disposition October 2004, 32 (10) 1061-1068; DOI: https://doi.org/10.1124/dmd.104.000224
    2. IDENTIFICATION AND METABOLISM OF A NOVEL DIHYDROHYDROXY-S-GLUTATHIONYL CONJUGATE OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST, MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL) PHENYL]METHYL]BENZAMIDE], IN RATS
      Vijay Bhasker G. Reddy, George A. Doss, Mellissa Creighton, Christopher J. Kochansky, Stella H. Vincent, Ronald B. Franklin and Bindhu V. Karanam
      Drug Metabolism and Disposition October 2004, 32 (10) 1154-1161; DOI: https://doi.org/10.1124/dmd.104.000240

  4. Katoh, Miki

    1. IDENTIFICATION OF THE CYTOSOLIC CARBOXYLESTERASE CATALYZING THE 5′-DEOXY-5-FLUOROCYTIDINE FORMATION FROM CAPECITABINE IN HUMAN LIVER
      Toshiki Tabata, Miki Katoh, Shogo Tokudome, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition October 2004, 32 (10) 1103-1110; DOI: https://doi.org/10.1124/dmd.104.000554

  5. Kochansky, Christopher J.

    1. IDENTIFICATION AND METABOLISM OF A NOVEL DIHYDROHYDROXY-S-GLUTATHIONYL CONJUGATE OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST, MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL) PHENYL]METHYL]BENZAMIDE], IN RATS
      Vijay Bhasker G. Reddy, George A. Doss, Mellissa Creighton, Christopher J. Kochansky, Stella H. Vincent, Ronald B. Franklin and Bindhu V. Karanam
      Drug Metabolism and Disposition October 2004, 32 (10) 1154-1161; DOI: https://doi.org/10.1124/dmd.104.000240

  6. Korolev, Dmitry

    1. QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1111-1120; DOI: https://doi.org/10.1124/dmd.104.000364
    2. KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey V. Skorenko, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1183-1189; DOI: https://doi.org/10.1124/dmd.104.000356

  7. Koyano, Nao

    1. IDENTIFICATION OF DI-(2-ETHYLHEXYL) PHTHALATE-INDUCED CARBOXYLESTERASE 1 IN C57BL/6 MOUSE LIVER MICROSOMES: PURIFICATION, CDNA CLONING, AND BACULOVIRUS-MEDIATED EXPRESSION
      Tomomi Furihata, Masakiyo Hosokawa, Nao Koyano, Takahiro Nakamura, Tetsuo Satoh and Kan Chiba
      Drug Metabolism and Disposition October 2004, 32 (10) 1170-1177; DOI: https://doi.org/10.1124/dmd.104.000620

  8. Kunze, Kent L.

    1. DIFFERENCES IN THE INHIBITION OF CYTOCHROMES P450 3A4 AND 3A5 BY METABOLITE-INHIBITOR COMPLEX-FORMING DRUGS
      Donavon J. McConn, Yvonne S. Lin, Kyle Allen, Kent L. Kunze and Kenneth E. Thummel
      Drug Metabolism and Disposition October 2004, 32 (10) 1083-1091; DOI: https://doi.org/10.1124/dmd.32.10.1083
    2. ROLE OF ITRACONAZOLE METABOLITES IN CYP3A4 INHIBITION
      Nina Isoherranen, Kent L. Kunze, Kyle E. Allen, Wendel L. Nelson and Kenneth E. Thummel
      Drug Metabolism and Disposition October 2004, 32 (10) 1121-1131; DOI: https://doi.org/10.1124/dmd.104.000315

L

  1. Latigo, J. R.

    1. PLASMA PHARMACOKINETICS AND METABOLISM OF THE HISTONE DEACETYLASE INHIBITOR TRICHOSTATIN A AFTER INTRAPERITONEAL ADMINISTRATION TO MICE
      L. Sanderson, G. W. Taylor, E. O. Aboagye, J. P. Alao, J. R. Latigo, R. C. Coombes and D. M. Vigushin
      Drug Metabolism and Disposition October 2004, 32 (10) 1132-1138; DOI: https://doi.org/10.1124/dmd.104.000638

  2. Lee, Frank W.

    1. EFFECTIVE DOSING REGIMEN OF 1-AMINOBENZOTRIAZOLE FOR INHIBITION OF ANTIPYRINE CLEARANCE IN GUINEA PIGS AND MICE USING SERIAL SAMPLING
      Suresh K. Balani, Ping Li, Joanne Nguyen, Kym Cardoza, Hang Zeng, Dun-Xue Mu, Jing-Tao Wu, Liang-Shang Gan and Frank W. Lee
      Drug Metabolism and Disposition October 2004, 32 (10) 1092-1095; DOI: https://doi.org/10.1124/dmd.104.000349

  3. Li, Ping

    1. EFFECTIVE DOSING REGIMEN OF 1-AMINOBENZOTRIAZOLE FOR INHIBITION OF ANTIPYRINE CLEARANCE IN GUINEA PIGS AND MICE USING SERIAL SAMPLING
      Suresh K. Balani, Ping Li, Joanne Nguyen, Kym Cardoza, Hang Zeng, Dun-Xue Mu, Jing-Tao Wu, Liang-Shang Gan and Frank W. Lee
      Drug Metabolism and Disposition October 2004, 32 (10) 1092-1095; DOI: https://doi.org/10.1124/dmd.104.000349

  4. Li, Wei

    1. ESTRADIOL 3-GLUCURONIDE IS TRANSPORTED BY THE MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2 BUT DOES NOT ACTIVATE THE ALLOSTERIC SITE BOUND BY ESTRADIOL 17-GLUCURONIDE
      Phillip M. Gerk, Wei Li and Mary Vore
      Drug Metabolism and Disposition October 2004, 32 (10) 1139-1145; DOI: https://doi.org/10.1124/dmd.104.000372

  5. Lin, Yvonne S.

    1. DIFFERENCES IN THE INHIBITION OF CYTOCHROMES P450 3A4 AND 3A5 BY METABOLITE-INHIBITOR COMPLEX-FORMING DRUGS
      Donavon J. McConn, Yvonne S. Lin, Kyle Allen, Kent L. Kunze and Kenneth E. Thummel
      Drug Metabolism and Disposition October 2004, 32 (10) 1083-1091; DOI: https://doi.org/10.1124/dmd.32.10.1083

M

  1. Maji, Daisuke

    1. SIMULTANEOUS EXPRESSION OF GUINEA PIG UDP-GLUCURONOSYLTRANSFERASE 2B21 (UGT2B21) AND 2B22 IN COS-7 CELLS ENHANCES UGT2B21-CATALYZED CHLORAMPHENICOL GLUCURONIDATION
      Yuji Ishii, Aya Miyoshi, Daisuke Maji, Hideyuki Yamada and Kazuta Oguri
      Drug Metabolism and Disposition October 2004, 32 (10) 1057-1060; DOI: https://doi.org/10.1124/dmd.32.10.1057

  2. Matsuda, Akira

    1. A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3′-ETHYNYL NUCLEOSIDES
      Daigo Murata, Yoshio Endo, Tohru Obata, Kazuki Sakamoto, Yasuhiro Syouji, Masakazu Kadohira, Akira Matsuda and Takuma Sasaki
      Drug Metabolism and Disposition October 2004, 32 (10) 1178-1182; DOI: https://doi.org/10.1124/dmd.104.000737

  3. McConn, Donavon J.

    1. DIFFERENCES IN THE INHIBITION OF CYTOCHROMES P450 3A4 AND 3A5 BY METABOLITE-INHIBITOR COMPLEX-FORMING DRUGS
      Donavon J. McConn, Yvonne S. Lin, Kyle Allen, Kent L. Kunze and Kenneth E. Thummel
      Drug Metabolism and Disposition October 2004, 32 (10) 1083-1091; DOI: https://doi.org/10.1124/dmd.32.10.1083

  4. Minematsu, Tsuyoshi

    1. CHARACTERIZATION OF THE RENAL TUBULAR TRANSPORT OF ZONAMPANEL, A NOVEL α-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID RECEPTOR ANTAGONIST, BY HUMAN ORGANIC ANION TRANSPORTERS
      Tadashi Hashimoto, Shinichi Narikawa, Xiu-Lin Huang, Tsuyoshi Minematsu, Takashi Usui, Hidetaka Kamimura and Hitoshi Endou
      Drug Metabolism and Disposition October 2004, 32 (10) 1096-1102; DOI: https://doi.org/10.1124/dmd.32.10.1096

  5. Miyoshi, Aya

    1. SIMULTANEOUS EXPRESSION OF GUINEA PIG UDP-GLUCURONOSYLTRANSFERASE 2B21 (UGT2B21) AND 2B22 IN COS-7 CELLS ENHANCES UGT2B21-CATALYZED CHLORAMPHENICOL GLUCURONIDATION
      Yuji Ishii, Aya Miyoshi, Daisuke Maji, Hideyuki Yamada and Kazuta Oguri
      Drug Metabolism and Disposition October 2004, 32 (10) 1057-1060; DOI: https://doi.org/10.1124/dmd.32.10.1057

  6. Mu, Dun-Xue

    1. EFFECTIVE DOSING REGIMEN OF 1-AMINOBENZOTRIAZOLE FOR INHIBITION OF ANTIPYRINE CLEARANCE IN GUINEA PIGS AND MICE USING SERIAL SAMPLING
      Suresh K. Balani, Ping Li, Joanne Nguyen, Kym Cardoza, Hang Zeng, Dun-Xue Mu, Jing-Tao Wu, Liang-Shang Gan and Frank W. Lee
      Drug Metabolism and Disposition October 2004, 32 (10) 1092-1095; DOI: https://doi.org/10.1124/dmd.104.000349

  7. Murata, Daigo

    1. A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3′-ETHYNYL NUCLEOSIDES
      Daigo Murata, Yoshio Endo, Tohru Obata, Kazuki Sakamoto, Yasuhiro Syouji, Masakazu Kadohira, Akira Matsuda and Takuma Sasaki
      Drug Metabolism and Disposition October 2004, 32 (10) 1178-1182; DOI: https://doi.org/10.1124/dmd.104.000737

N

  1. Nakajima, Miki

    1. IDENTIFICATION OF THE CYTOSOLIC CARBOXYLESTERASE CATALYZING THE 5′-DEOXY-5-FLUOROCYTIDINE FORMATION FROM CAPECITABINE IN HUMAN LIVER
      Toshiki Tabata, Miki Katoh, Shogo Tokudome, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition October 2004, 32 (10) 1103-1110; DOI: https://doi.org/10.1124/dmd.104.000554

  2. Nakamura, Takahiro

    1. IDENTIFICATION OF DI-(2-ETHYLHEXYL) PHTHALATE-INDUCED CARBOXYLESTERASE 1 IN C57BL/6 MOUSE LIVER MICROSOMES: PURIFICATION, CDNA CLONING, AND BACULOVIRUS-MEDIATED EXPRESSION
      Tomomi Furihata, Masakiyo Hosokawa, Nao Koyano, Takahiro Nakamura, Tetsuo Satoh and Kan Chiba
      Drug Metabolism and Disposition October 2004, 32 (10) 1170-1177; DOI: https://doi.org/10.1124/dmd.104.000620

  3. Narikawa, Shinichi

    1. CHARACTERIZATION OF THE RENAL TUBULAR TRANSPORT OF ZONAMPANEL, A NOVEL α-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID RECEPTOR ANTAGONIST, BY HUMAN ORGANIC ANION TRANSPORTERS
      Tadashi Hashimoto, Shinichi Narikawa, Xiu-Lin Huang, Tsuyoshi Minematsu, Takashi Usui, Hidetaka Kamimura and Hitoshi Endou
      Drug Metabolism and Disposition October 2004, 32 (10) 1096-1102; DOI: https://doi.org/10.1124/dmd.32.10.1096

  4. Nelson, Wendel L.

    1. ROLE OF ITRACONAZOLE METABOLITES IN CYP3A4 INHIBITION
      Nina Isoherranen, Kent L. Kunze, Kyle E. Allen, Wendel L. Nelson and Kenneth E. Thummel
      Drug Metabolism and Disposition October 2004, 32 (10) 1121-1131; DOI: https://doi.org/10.1124/dmd.104.000315

  5. Nguyen, Joanne

    1. EFFECTIVE DOSING REGIMEN OF 1-AMINOBENZOTRIAZOLE FOR INHIBITION OF ANTIPYRINE CLEARANCE IN GUINEA PIGS AND MICE USING SERIAL SAMPLING
      Suresh K. Balani, Ping Li, Joanne Nguyen, Kym Cardoza, Hang Zeng, Dun-Xue Mu, Jing-Tao Wu, Liang-Shang Gan and Frank W. Lee
      Drug Metabolism and Disposition October 2004, 32 (10) 1092-1095; DOI: https://doi.org/10.1124/dmd.104.000349

  6. Nikolskaya, Tatiana

    1. QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1111-1120; DOI: https://doi.org/10.1124/dmd.104.000364
    2. KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey V. Skorenko, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1183-1189; DOI: https://doi.org/10.1124/dmd.104.000356

  7. Nikolsky, Yuri V.

    1. QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1111-1120; DOI: https://doi.org/10.1124/dmd.104.000364
    2. KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey V. Skorenko, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1183-1189; DOI: https://doi.org/10.1124/dmd.104.000356

  8. Nishi, Koji

    1. CONSTRUCTION OF EXPRESSION SYSTEM FOR HUMAN α1-ACID GLYCOPROTEIN IN PICHIA PASTORIS AND EVALUATION OF ITS DRUG-BINDING PROPERTIES
      Koji Nishi, Naoko Fukunaga and Masaki Otagiri
      Drug Metabolism and Disposition October 2004, 32 (10) 1069-1074; DOI: https://doi.org/10.1124/dmd.104.000513

  9. Nocerini, Mark R.

    1. UTILITY OF WHOLE-BODY AUTORADIOLUMINOGRAPHY IN DRUG DISCOVERY FOR THE QUANTIFICATION OF TRITIUM-LABELED DRUG CANDIDATES
      Michael J. Potchoiba and Mark R. Nocerini
      Drug Metabolism and Disposition October 2004, 32 (10) 1190-1198; DOI: https://doi.org/10.1124/dmd.32.10.1190

O

  1. Obata, Tohru

    1. A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3′-ETHYNYL NUCLEOSIDES
      Daigo Murata, Yoshio Endo, Tohru Obata, Kazuki Sakamoto, Yasuhiro Syouji, Masakazu Kadohira, Akira Matsuda and Takuma Sasaki
      Drug Metabolism and Disposition October 2004, 32 (10) 1178-1182; DOI: https://doi.org/10.1124/dmd.104.000737

  2. Oguri, Kazuta

    1. SIMULTANEOUS EXPRESSION OF GUINEA PIG UDP-GLUCURONOSYLTRANSFERASE 2B21 (UGT2B21) AND 2B22 IN COS-7 CELLS ENHANCES UGT2B21-CATALYZED CHLORAMPHENICOL GLUCURONIDATION
      Yuji Ishii, Aya Miyoshi, Daisuke Maji, Hideyuki Yamada and Kazuta Oguri
      Drug Metabolism and Disposition October 2004, 32 (10) 1057-1060; DOI: https://doi.org/10.1124/dmd.32.10.1057

  3. Otagiri, Masaki

    1. CONSTRUCTION OF EXPRESSION SYSTEM FOR HUMAN α1-ACID GLYCOPROTEIN IN PICHIA PASTORIS AND EVALUATION OF ITS DRUG-BINDING PROPERTIES
      Koji Nishi, Naoko Fukunaga and Masaki Otagiri
      Drug Metabolism and Disposition October 2004, 32 (10) 1069-1074; DOI: https://doi.org/10.1124/dmd.104.000513

P

  1. Paine, Mary F.

    1. TWO MAJOR GRAPEFRUIT JUICE COMPONENTS DIFFER IN INTESTINAL CYP3A4 INHIBITION KINETIC AND BINDING PROPERTIES
      Mary F. Paine, Anne B. Criss and Paul B. Watkins
      Drug Metabolism and Disposition October 2004, 32 (10) 1146-1153; DOI: https://doi.org/10.1124/dmd.104.000547

  2. Potchoiba, Michael J.

    1. UTILITY OF WHOLE-BODY AUTORADIOLUMINOGRAPHY IN DRUG DISCOVERY FOR THE QUANTIFICATION OF TRITIUM-LABELED DRUG CANDIDATES
      Michael J. Potchoiba and Mark R. Nocerini
      Drug Metabolism and Disposition October 2004, 32 (10) 1190-1198; DOI: https://doi.org/10.1124/dmd.32.10.1190

R

  1. Reddy, Vijay Bhasker G.

    1. IDENTIFICATION AND METABOLISM OF A NOVEL DIHYDROHYDROXY-S-GLUTATHIONYL CONJUGATE OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST, MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL) PHENYL]METHYL]BENZAMIDE], IN RATS
      Vijay Bhasker G. Reddy, George A. Doss, Mellissa Creighton, Christopher J. Kochansky, Stella H. Vincent, Ronald B. Franklin and Bindhu V. Karanam
      Drug Metabolism and Disposition October 2004, 32 (10) 1154-1161; DOI: https://doi.org/10.1124/dmd.104.000240

  2. Reddy, Vijay G.

    1. SPECIES DIFFERENTIAL STEREOSELECTIVE OXIDATION OF A METHYLSULFIDE METABOLITE OF MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL)PHENYL]METHYL]BENZAMIDE], A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DUAL AGONIST
      Bindhu V. Karanam, Christopher J. Welch, Vijay G. Reddy, Jennifer Chilenski, Mirlinda Biba and Stella Vincent
      Drug Metabolism and Disposition October 2004, 32 (10) 1061-1068; DOI: https://doi.org/10.1124/dmd.104.000224

S

  1. Sadatrafiei, Asal

    1. TOCOTRIENOLS ACTIVATE THE STEROID AND XENOBIOTIC RECEPTOR, SXR, AND SELECTIVELY REGULATE EXPRESSION OF ITS TARGET GENES
      Changcheng Zhou, Michelle M. Tabb, Asal Sadatrafiei, Felix Grün and Bruce Blumberg
      Drug Metabolism and Disposition October 2004, 32 (10) 1075-1082; DOI: https://doi.org/10.1124/dmd.104.000299

  2. Sakamoto, Kazuki

    1. A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3′-ETHYNYL NUCLEOSIDES
      Daigo Murata, Yoshio Endo, Tohru Obata, Kazuki Sakamoto, Yasuhiro Syouji, Masakazu Kadohira, Akira Matsuda and Takuma Sasaki
      Drug Metabolism and Disposition October 2004, 32 (10) 1178-1182; DOI: https://doi.org/10.1124/dmd.104.000737

  3. Sanderson, L.

    1. PLASMA PHARMACOKINETICS AND METABOLISM OF THE HISTONE DEACETYLASE INHIBITOR TRICHOSTATIN A AFTER INTRAPERITONEAL ADMINISTRATION TO MICE
      L. Sanderson, G. W. Taylor, E. O. Aboagye, J. P. Alao, J. R. Latigo, R. C. Coombes and D. M. Vigushin
      Drug Metabolism and Disposition October 2004, 32 (10) 1132-1138; DOI: https://doi.org/10.1124/dmd.104.000638

  4. Sasaki, Takuma

    1. A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3′-ETHYNYL NUCLEOSIDES
      Daigo Murata, Yoshio Endo, Tohru Obata, Kazuki Sakamoto, Yasuhiro Syouji, Masakazu Kadohira, Akira Matsuda and Takuma Sasaki
      Drug Metabolism and Disposition October 2004, 32 (10) 1178-1182; DOI: https://doi.org/10.1124/dmd.104.000737

  5. Satoh, Tetsuo

    1. IDENTIFICATION OF DI-(2-ETHYLHEXYL) PHTHALATE-INDUCED CARBOXYLESTERASE 1 IN C57BL/6 MOUSE LIVER MICROSOMES: PURIFICATION, CDNA CLONING, AND BACULOVIRUS-MEDIATED EXPRESSION
      Tomomi Furihata, Masakiyo Hosokawa, Nao Koyano, Takahiro Nakamura, Tetsuo Satoh and Kan Chiba
      Drug Metabolism and Disposition October 2004, 32 (10) 1170-1177; DOI: https://doi.org/10.1124/dmd.104.000620

  6. Savchuk, Nikolay P.

    1. QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1111-1120; DOI: https://doi.org/10.1124/dmd.104.000364
    2. KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey V. Skorenko, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1183-1189; DOI: https://doi.org/10.1124/dmd.104.000356

  7. Skorenko, Andrey V.

    1. KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4
      Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey V. Skorenko, Andrey A. Ivashchenko, Nikolay P. Savchuk and Tatiana Nikolskaya
      Drug Metabolism and Disposition October 2004, 32 (10) 1183-1189; DOI: https://doi.org/10.1124/dmd.104.000356

  8. Syouji, Yasuhiro

    1. A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3′-ETHYNYL NUCLEOSIDES
      Daigo Murata, Yoshio Endo, Tohru Obata, Kazuki Sakamoto, Yasuhiro Syouji, Masakazu Kadohira, Akira Matsuda and Takuma Sasaki
      Drug Metabolism and Disposition October 2004, 32 (10) 1178-1182; DOI: https://doi.org/10.1124/dmd.104.000737

T

  1. Tabata, Toshiki

    1. IDENTIFICATION OF THE CYTOSOLIC CARBOXYLESTERASE CATALYZING THE 5′-DEOXY-5-FLUOROCYTIDINE FORMATION FROM CAPECITABINE IN HUMAN LIVER
      Toshiki Tabata, Miki Katoh, Shogo Tokudome, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition October 2004, 32 (10) 1103-1110; DOI: https://doi.org/10.1124/dmd.104.000554

  2. Tabb, Michelle M.

    1. TOCOTRIENOLS ACTIVATE THE STEROID AND XENOBIOTIC RECEPTOR, SXR, AND SELECTIVELY REGULATE EXPRESSION OF ITS TARGET GENES
      Changcheng Zhou, Michelle M. Tabb, Asal Sadatrafiei, Felix Grün and Bruce Blumberg
      Drug Metabolism and Disposition October 2004, 32 (10) 1075-1082; DOI: https://doi.org/10.1124/dmd.104.000299

  3. Taylor, G. W.

    1. PLASMA PHARMACOKINETICS AND METABOLISM OF THE HISTONE DEACETYLASE INHIBITOR TRICHOSTATIN A AFTER INTRAPERITONEAL ADMINISTRATION TO MICE
      L. Sanderson, G. W. Taylor, E. O. Aboagye, J. P. Alao, J. R. Latigo, R. C. Coombes and D. M. Vigushin
      Drug Metabolism and Disposition October 2004, 32 (10) 1132-1138; DOI: https://doi.org/10.1124/dmd.104.000638

  4. Thummel, Kenneth E.

    1. DIFFERENCES IN THE INHIBITION OF CYTOCHROMES P450 3A4 AND 3A5 BY METABOLITE-INHIBITOR COMPLEX-FORMING DRUGS
      Donavon J. McConn, Yvonne S. Lin, Kyle Allen, Kent L. Kunze and Kenneth E. Thummel
      Drug Metabolism and Disposition October 2004, 32 (10) 1083-1091; DOI: https://doi.org/10.1124/dmd.32.10.1083
    2. ROLE OF ITRACONAZOLE METABOLITES IN CYP3A4 INHIBITION
      Nina Isoherranen, Kent L. Kunze, Kyle E. Allen, Wendel L. Nelson and Kenneth E. Thummel
      Drug Metabolism and Disposition October 2004, 32 (10) 1121-1131; DOI: https://doi.org/10.1124/dmd.104.000315

  5. Tokudome, Shogo

    1. IDENTIFICATION OF THE CYTOSOLIC CARBOXYLESTERASE CATALYZING THE 5′-DEOXY-5-FLUOROCYTIDINE FORMATION FROM CAPECITABINE IN HUMAN LIVER
      Toshiki Tabata, Miki Katoh, Shogo Tokudome, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition October 2004, 32 (10) 1103-1110; DOI: https://doi.org/10.1124/dmd.104.000554

U

  1. Usui, Takashi

    1. CHARACTERIZATION OF THE RENAL TUBULAR TRANSPORT OF ZONAMPANEL, A NOVEL α-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID RECEPTOR ANTAGONIST, BY HUMAN ORGANIC ANION TRANSPORTERS
      Tadashi Hashimoto, Shinichi Narikawa, Xiu-Lin Huang, Tsuyoshi Minematsu, Takashi Usui, Hidetaka Kamimura and Hitoshi Endou
      Drug Metabolism and Disposition October 2004, 32 (10) 1096-1102; DOI: https://doi.org/10.1124/dmd.32.10.1096

V

  1. Vigushin, D. M.

    1. PLASMA PHARMACOKINETICS AND METABOLISM OF THE HISTONE DEACETYLASE INHIBITOR TRICHOSTATIN A AFTER INTRAPERITONEAL ADMINISTRATION TO MICE
      L. Sanderson, G. W. Taylor, E. O. Aboagye, J. P. Alao, J. R. Latigo, R. C. Coombes and D. M. Vigushin
      Drug Metabolism and Disposition October 2004, 32 (10) 1132-1138; DOI: https://doi.org/10.1124/dmd.104.000638

  2. Vincent, Stella

    1. SPECIES DIFFERENTIAL STEREOSELECTIVE OXIDATION OF A METHYLSULFIDE METABOLITE OF MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL)PHENYL]METHYL]BENZAMIDE], A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DUAL AGONIST
      Bindhu V. Karanam, Christopher J. Welch, Vijay G. Reddy, Jennifer Chilenski, Mirlinda Biba and Stella Vincent
      Drug Metabolism and Disposition October 2004, 32 (10) 1061-1068; DOI: https://doi.org/10.1124/dmd.104.000224

  3. Vincent, Stella H.

    1. IDENTIFICATION AND METABOLISM OF A NOVEL DIHYDROHYDROXY-S-GLUTATHIONYL CONJUGATE OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST, MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL) PHENYL]METHYL]BENZAMIDE], IN RATS
      Vijay Bhasker G. Reddy, George A. Doss, Mellissa Creighton, Christopher J. Kochansky, Stella H. Vincent, Ronald B. Franklin and Bindhu V. Karanam
      Drug Metabolism and Disposition October 2004, 32 (10) 1154-1161; DOI: https://doi.org/10.1124/dmd.104.000240

  4. Vore, Mary

    1. ESTRADIOL 3-GLUCURONIDE IS TRANSPORTED BY THE MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2 BUT DOES NOT ACTIVATE THE ALLOSTERIC SITE BOUND BY ESTRADIOL 17-GLUCURONIDE
      Phillip M. Gerk, Wei Li and Mary Vore
      Drug Metabolism and Disposition October 2004, 32 (10) 1139-1145; DOI: https://doi.org/10.1124/dmd.104.000372

W

  1. Wang, Li-Quan

    1. TRICLOSAN AS A SUBSTRATE AND INHIBITOR OF 3′-PHOSPHOADENOSINE 5′-PHOSPHOSULFATE-SULFOTRANSFERASE AND UDP-GLUCURONOSYL TRANSFERASE IN HUMAN LIVER FRACTIONS
      Li-Quan Wang, Charles N. Falany and Margaret O. James
      Drug Metabolism and Disposition October 2004, 32 (10) 1162-1169; DOI: https://doi.org/10.1124/dmd.104.000273

  2. Watkins, Paul B.

    1. TWO MAJOR GRAPEFRUIT JUICE COMPONENTS DIFFER IN INTESTINAL CYP3A4 INHIBITION KINETIC AND BINDING PROPERTIES
      Mary F. Paine, Anne B. Criss and Paul B. Watkins
      Drug Metabolism and Disposition October 2004, 32 (10) 1146-1153; DOI: https://doi.org/10.1124/dmd.104.000547

  3. Welch, Christopher J.

    1. SPECIES DIFFERENTIAL STEREOSELECTIVE OXIDATION OF A METHYLSULFIDE METABOLITE OF MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL)PHENYL]METHYL]BENZAMIDE], A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DUAL AGONIST
      Bindhu V. Karanam, Christopher J. Welch, Vijay G. Reddy, Jennifer Chilenski, Mirlinda Biba and Stella Vincent
      Drug Metabolism and Disposition October 2004, 32 (10) 1061-1068; DOI: https://doi.org/10.1124/dmd.104.000224

  4. Wu, Jing-Tao

    1. EFFECTIVE DOSING REGIMEN OF 1-AMINOBENZOTRIAZOLE FOR INHIBITION OF ANTIPYRINE CLEARANCE IN GUINEA PIGS AND MICE USING SERIAL SAMPLING
      Suresh K. Balani, Ping Li, Joanne Nguyen, Kym Cardoza, Hang Zeng, Dun-Xue Mu, Jing-Tao Wu, Liang-Shang Gan and Frank W. Lee
      Drug Metabolism and Disposition October 2004, 32 (10) 1092-1095; DOI: https://doi.org/10.1124/dmd.104.000349

Y

  1. Yamada, Hideyuki

    1. SIMULTANEOUS EXPRESSION OF GUINEA PIG UDP-GLUCURONOSYLTRANSFERASE 2B21 (UGT2B21) AND 2B22 IN COS-7 CELLS ENHANCES UGT2B21-CATALYZED CHLORAMPHENICOL GLUCURONIDATION
      Yuji Ishii, Aya Miyoshi, Daisuke Maji, Hideyuki Yamada and Kazuta Oguri
      Drug Metabolism and Disposition October 2004, 32 (10) 1057-1060; DOI: https://doi.org/10.1124/dmd.32.10.1057

  2. Yokoi, Tsuyoshi

    1. IDENTIFICATION OF THE CYTOSOLIC CARBOXYLESTERASE CATALYZING THE 5′-DEOXY-5-FLUOROCYTIDINE FORMATION FROM CAPECITABINE IN HUMAN LIVER
      Toshiki Tabata, Miki Katoh, Shogo Tokudome, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition October 2004, 32 (10) 1103-1110; DOI: https://doi.org/10.1124/dmd.104.000554

Z

  1. Zeng, Hang

    1. EFFECTIVE DOSING REGIMEN OF 1-AMINOBENZOTRIAZOLE FOR INHIBITION OF ANTIPYRINE CLEARANCE IN GUINEA PIGS AND MICE USING SERIAL SAMPLING
      Suresh K. Balani, Ping Li, Joanne Nguyen, Kym Cardoza, Hang Zeng, Dun-Xue Mu, Jing-Tao Wu, Liang-Shang Gan and Frank W. Lee
      Drug Metabolism and Disposition October 2004, 32 (10) 1092-1095; DOI: https://doi.org/10.1124/dmd.104.000349

  2. Zhou, Changcheng

    1. TOCOTRIENOLS ACTIVATE THE STEROID AND XENOBIOTIC RECEPTOR, SXR, AND SELECTIVELY REGULATE EXPRESSION OF ITS TARGET GENES
      Changcheng Zhou, Michelle M. Tabb, Asal Sadatrafiei, Felix Grün and Bruce Blumberg
      Drug Metabolism and Disposition October 2004, 32 (10) 1075-1082; DOI: https://doi.org/10.1124/dmd.104.000299
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