DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS

Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, Ann Arbor, Michigan (J.A.W, S.H., T.C.G., V.P., J.R.K., S.E.B.), and Sandwich, Kent, United Kingdom (R.H., B.C.G., D.A.S.)

Address correspondence to:
J. Andrew Williams, Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, 2800 Plymouth Road, Ann Arbor, MI 48105. E-mail: james.williams2{at}pfizer.com

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