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Research ArticleArticle

STRUCTURAL ANALYSIS OF CYP2C9 AND CYP2C5 AND AN EVALUATION OF COMMONLY USED MOLECULAR MODELING TECHNIQUES

Lovisa Afzelius, Florian Raubacher, Anders Karlén, Flemming Steen Jørgensen, Tommy B. Andersson, Collen M. Masimirembwa and Ismael Zamora
Drug Metabolism and Disposition November 2004, 32 (11) 1218-1229; DOI: https://doi.org/10.1124/dmd.32.11.1218
Lovisa Afzelius
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Florian Raubacher
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Anders Karlén
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Flemming Steen Jørgensen
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Tommy B. Andersson
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Collen M. Masimirembwa
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Ismael Zamora
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Article Information

vol. 32 no. 11 1218-1229
DOI 
https://doi.org/10.1124/dmd.32.11.1218

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 26, 2004
  • Accepted July 12, 2004
  • Published online October 13, 2004.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Lovisa Afzelius,
  2. Florian Raubacher,
  3. Anders Karlén,
  4. Flemming Steen Jørgensen,
  5. Tommy B. Andersson,
  6. Collen M. Masimirembwa and
  7. Ismael Zamora
  1. Department of Drug Metabolism and Pharmacokinetics and Bioanalytical Chemistry (L.A., T.B.A., C.M.M.) and Department of Medicinal Chemistry (F.R.), AstraZeneca R&D, Mölndal, Sweden; Department of Organic Pharmaceutical Chemistry, Uppsala University, Uppsala, Sweden (L.A., A.K.); Lead Molecular Design, Barcelona, Spain (I.Z.); Institut Municipal d'Investigació Mèdica, Barcelona, Spain (I.Z.); and Department of Medicinal Chemistry, the Danish University of Pharmaceutical Science, Copenhagen, Denmark (L.A., F.S.J.)
  1. Address correspondence to:
    Lovisa Afzelius, AstraZeneca R&D, Mölndal,S-431 83 Mölndal, Sweden. E-mail: Lovisa.afzelius{at}astrazeneca.com
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Drug Metabolism and Disposition: 32 (11)
Drug Metabolism and Disposition
Vol. 32, Issue 11
1 Nov 2004
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Research ArticleArticle

STRUCTURAL ANALYSIS OF CYP2C9 AND CYP2C5 AND AN EVALUATION OF COMMONLY USED MOLECULAR MODELING TECHNIQUES

Lovisa Afzelius, Florian Raubacher, Anders Karlén, Flemming Steen Jørgensen, Tommy B. Andersson, Collen M. Masimirembwa and Ismael Zamora
Drug Metabolism and Disposition November 1, 2004, 32 (11) 1218-1229; DOI: https://doi.org/10.1124/dmd.32.11.1218

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Research ArticleArticle

STRUCTURAL ANALYSIS OF CYP2C9 AND CYP2C5 AND AN EVALUATION OF COMMONLY USED MOLECULAR MODELING TECHNIQUES

Lovisa Afzelius, Florian Raubacher, Anders Karlén, Flemming Steen Jørgensen, Tommy B. Andersson, Collen M. Masimirembwa and Ismael Zamora
Drug Metabolism and Disposition November 1, 2004, 32 (11) 1218-1229; DOI: https://doi.org/10.1124/dmd.32.11.1218
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