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Research ArticleArticle

EVALUATION OF FRESH AND CRYOPRESERVED HEPATOCYTES AS IN VITRO DRUG METABOLISM TOOLS FOR THE PREDICTION OF METABOLIC CLEARANCE

Dermot F. McGinnity, Matthew G. Soars, Richard A. Urbanowicz and Robert J. Riley
Drug Metabolism and Disposition November 2004, 32 (11) 1247-1253; DOI: https://doi.org/10.1124/dmd.104.000026

Article Information

vol. 32 no. 11 1247-1253
DOI 
https://doi.org/10.1124/dmd.104.000026
PubMed 
15286053
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 30, 2004
  • Accepted July 30, 2004
  • Published online October 13, 2004.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Dermot F. McGinnity,
  2. Matthew G. Soars,
  3. Richard A. Urbanowicz and
  4. Robert J. Riley
  1. Department of Physical & Metabolic Science, AstraZeneca R&D Charnwood, Leicestershire, United Kingdom
  1. Address correspondence to:
    Dr. Dermot McGinnity, Department of Physical & Metabolic Science, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leicestershire, LE11 5RH, UK. E-mail: dermot.f.mcginnity{at}astrazeneca.com
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Research ArticleArticle

EVALUATION OF FRESH AND CRYOPRESERVED HEPATOCYTES AS IN VITRO DRUG METABOLISM TOOLS FOR THE PREDICTION OF METABOLIC CLEARANCE

Dermot F. McGinnity, Matthew G. Soars, Richard A. Urbanowicz and Robert J. Riley
Drug Metabolism and Disposition November 1, 2004, 32 (11) 1247-1253; DOI: https://doi.org/10.1124/dmd.104.000026
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