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Index by author

December 01, 2004; Volume 32,Issue 12

A

  1. Adachi, Yasuhisa

    1. IN VITRO AND IN VIVO CORRELATION OF THE INHIBITORY EFFECT OF CYCLOSPORIN A ON THE TRANSPORTER-MEDIATED HEPATIC UPTAKE OF CERIVASTATIN IN RATS
      Yoshihisa Shitara, Masaru Hirano, Yasuhisa Adachi, Tomoo Itoh, Hitoshi Sato and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2004, 32 (12) 1468-1475; DOI: https://doi.org/10.1124/dmd.32.12.1468

  2. Alley, Michael C.

    1. FLUORINATED 2-(4-AMINO-3-METHYLPHENYL)BENZOTHIAZOLES INDUCE CYP1A1 EXPRESSION, BECOME METABOLIZED, AND BIND TO MACROMOLECULES IN SENSITIVE HUMAN CANCER CELLS
      Eileen Brantley, Valentina Trapani, Michael C. Alley, Curtis D. Hose, Tracey D. Bradshaw, Malcolm F. G. Stevens, Edward A. Sausville and Sherman F. Stinson
      Drug Metabolism and Disposition December 2004, 32 (12) 1392-1401; DOI: https://doi.org/10.1124/dmd.104.001057

  3. Alvarez-Diez, Teresa M.

    1. DETECTION OF GLUTATHIONE CONJUGATES DERIVED FROM 4-IPOMEANOL METABOLISM IN BILE OF RATS BY LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY
      Teresa M. Alvarez-Diez and Jiang Zheng
      Drug Metabolism and Disposition December 2004, 32 (12) 1345-1350; DOI: https://doi.org/10.1124/dmd.104.000406

  4. Andersson, Tommy B.

    1. RESPONSE: PREDICTING THE CLEARANCE OF CYP2C9 SUBSTRATES
      Tommy B. Andersson, Eva Bredberg, Hans Ericsson and Helena SjÖberg
      Drug Metabolism and Disposition December 2004, 32 (12) 1523; DOI: https://doi.org/10.1124/dmd.104.002329

  5. Antonio, Laurence

    1. ASSESSMENT OF CATECHOL INDUCTION AND GLUCURONIDATION IN RAT LIVER MICROSOMES
      Eivor Elovaara, Jouni Mikkola, Leena Luukkanen, Laurence Antonio, Sylvie Fournel-Gigleux, Brian Burchell, Jacques Magdalou and Jyrki Taskinen
      Drug Metabolism and Disposition December 2004, 32 (12) 1426-1433; DOI: https://doi.org/10.1124/dmd.104.000992

  6. Apak, T. Idil

    1. INTERACTIONS OF THE STEREOISOMERS OF α-HYDROXYTAMOXIFEN WITH HUMAN HYDROXYSTEROID SULFOTRANSFERASE SULT2A1 AND RAT HYDROXYSTEROID SULFOTRANSFERASE STA
      T. Idil Apak and Michael W. Duffel
      Drug Metabolism and Disposition December 2004, 32 (12) 1501-1508; DOI: https://doi.org/10.1124/dmd.104.000919

  7. Ardlie, Kristin G.

    1. DIFFERENCES IN FMO2*1 ALLELIC FREQUENCY BETWEEN HISPANICS OF PUERTO RICAN AND MEXICAN DESCENT
      Sharon K. Krueger, Lisbeth K. Siddens, Sarah R. Martin, Zhen Yu, Clifford B. Pereira, Erwin T. Cabacungan, Ronald N. Hines, Kristin G. Ardlie, Judy L. Raucy and David E. Williams
      Drug Metabolism and Disposition December 2004, 32 (12) 1337-1340; DOI: https://doi.org/10.1124/dmd.104.001099

B

  1. Bai, Stephen A.

    1. THE CHIMPANZEE (PAN TROGLODYTES) AS A PHARMACOKINETIC MODEL FOR SELECTION OF DRUG CANDIDATES: MODEL CHARACTERIZATION AND APPLICATION
      Harvey Wong, Scott J. Grossman, Stephen A. Bai, Sharon Diamond, Matthew R. Wright, James E. Grace, Mingxin Qian, Kan He, Krishnaswamy Yeleswaram and David D. Christ
      Drug Metabolism and Disposition December 2004, 32 (12) 1359-1369; DOI: https://doi.org/10.1124/dmd.104.000943

  2. Basu, N. K.

    1. RESPONSE TO THE LETTER TO THE EDITOR BY DRS. N. PICARD AND P. MARQUET REGARDING A PUBLICATION: BASU ET AL., DRUG METABOLISM AND DISPOSITION (32:768–773, (2004)
      N. K. Basu, L. Kole, S. Kubota and I. S. Owens
      Drug Metabolism and Disposition December 2004, 32 (12) 1525; DOI: https://doi.org/10.1124/dmd.104.002345

  3. Berry, Pamela W.

    1. IDENTIFICATION OF GLUTATHIONE-DERIVED METABOLITES FROM AN IP RECEPTOR ANTAGONIST
      William L. Fitch, Pamela W. Berry, Yaping Tu, Ali Tabatabaei, Lee Lowrie, Francisco Lopez-Tapia, Yanzhou Liu, Dov Nitzan, Mohammad R. Masjedizadeh and Aravamuthan Varadarajan
      Drug Metabolism and Disposition December 2004, 32 (12) 1482-1490; DOI: https://doi.org/10.1124/dmd.104.000471

  4. Bradshaw, Tracey D.

    1. FLUORINATED 2-(4-AMINO-3-METHYLPHENYL)BENZOTHIAZOLES INDUCE CYP1A1 EXPRESSION, BECOME METABOLIZED, AND BIND TO MACROMOLECULES IN SENSITIVE HUMAN CANCER CELLS
      Eileen Brantley, Valentina Trapani, Michael C. Alley, Curtis D. Hose, Tracey D. Bradshaw, Malcolm F. G. Stevens, Edward A. Sausville and Sherman F. Stinson
      Drug Metabolism and Disposition December 2004, 32 (12) 1392-1401; DOI: https://doi.org/10.1124/dmd.104.001057

  5. Brantley, Eileen

    1. FLUORINATED 2-(4-AMINO-3-METHYLPHENYL)BENZOTHIAZOLES INDUCE CYP1A1 EXPRESSION, BECOME METABOLIZED, AND BIND TO MACROMOLECULES IN SENSITIVE HUMAN CANCER CELLS
      Eileen Brantley, Valentina Trapani, Michael C. Alley, Curtis D. Hose, Tracey D. Bradshaw, Malcolm F. G. Stevens, Edward A. Sausville and Sherman F. Stinson
      Drug Metabolism and Disposition December 2004, 32 (12) 1392-1401; DOI: https://doi.org/10.1124/dmd.104.001057

  6. Bredberg, Eva

    1. RESPONSE: PREDICTING THE CLEARANCE OF CYP2C9 SUBSTRATES
      Tommy B. Andersson, Eva Bredberg, Hans Ericsson and Helena SjÖberg
      Drug Metabolism and Disposition December 2004, 32 (12) 1523; DOI: https://doi.org/10.1124/dmd.104.002329

  7. Brown, Caroline

    1. UTILITY OF RECOMBINANT ENZYME KINETICS IN PREDICTION OF HUMAN CLEARANCE: IMPACT OF VARIABILITY, CYP3A5, AND CYP2C19 ON CYP3A4 PROBE SUBSTRATES
      Aleksandra Galetin, Caroline Brown, David Hallifax, Kiyomi Ito and J. Brian Houston
      Drug Metabolism and Disposition December 2004, 32 (12) 1411-1420; DOI: https://doi.org/10.1124/dmd.104.000844

  8. Burchell, Brian

    1. ASSESSMENT OF CATECHOL INDUCTION AND GLUCURONIDATION IN RAT LIVER MICROSOMES
      Eivor Elovaara, Jouni Mikkola, Leena Luukkanen, Laurence Antonio, Sylvie Fournel-Gigleux, Brian Burchell, Jacques Magdalou and Jyrki Taskinen
      Drug Metabolism and Disposition December 2004, 32 (12) 1426-1433; DOI: https://doi.org/10.1124/dmd.104.000992
    2. IDENTIFICATION OF THE RABBIT LIVER UDP-GLUCURONOSYLTRANSFERASE CATALYZING THE GLUCURONIDATION OF 4-ETHOXYPHENYLUREA (DULCIN)
      Yoshihiro Uesawa, Adam G. Staines, Audrey O'Sullivan, Kiminori Mohri and Brian Burchell
      Drug Metabolism and Disposition December 2004, 32 (12) 1476-1481; DOI: https://doi.org/10.1124/dmd.104.001206

C

  1. Cabacungan, Erwin T.

    1. DIFFERENCES IN FMO2*1 ALLELIC FREQUENCY BETWEEN HISPANICS OF PUERTO RICAN AND MEXICAN DESCENT
      Sharon K. Krueger, Lisbeth K. Siddens, Sarah R. Martin, Zhen Yu, Clifford B. Pereira, Erwin T. Cabacungan, Ronald N. Hines, Kristin G. Ardlie, Judy L. Raucy and David E. Williams
      Drug Metabolism and Disposition December 2004, 32 (12) 1337-1340; DOI: https://doi.org/10.1124/dmd.104.001099

  2. Calamia, Justina C.

    1. EVIDENCE OF SIGNIFICANT CONTRIBUTION FROM CYP3A5 TO HEPATIC DRUG METABOLISM
      Weili Huang, Yvonne S. Lin, Donavon J. McConn, Justina C. Calamia, Rheem A. Totah, Nina Isoherranen, Mary Glodowski and Kenneth E. Thummel
      Drug Metabolism and Disposition December 2004, 32 (12) 1434-1445; DOI: https://doi.org/10.1124/dmd.104.001313

  3. Chauret, Nathalie

    1. USE OF A BENZYLOXY-SUBSTITUTED LACTONE CYCLOOXYGENASE-2 INHIBITOR AS A SELECTIVE FLUORESCENT PROBE FOR CYP3A ACTIVITY IN PRIMARY CULTURED RAT AND HUMAN HEPATOCYTES
      Deborah A. Nicoll-Griffith, Nathalie Chauret, Robert Houle, Stephen H. Day, Michelle D'Antoni and José M. Silva
      Drug Metabolism and Disposition December 2004, 32 (12) 1509-1515; DOI: https://doi.org/10.1124/dmd.32.12.1509

  4. Chavin, Kenneth D.

    1. MULTIPLE NIGHT-TIME DOSES OF VALERIAN (Valeriana officinalis) HAD MINIMAL EFFECTS ON CYP3A4 ACTIVITY AND NO EFFECT ON CYP2D6 ACTIVITY IN HEALTHY VOLUNTEERS
      Jennifer L. Donovan, C. Lindsay DeVane, Kenneth D. Chavin, Jun-Sheng Wang, Bryan B. Gibson, Holly A. Gefroh and John S. Markowitz
      Drug Metabolism and Disposition December 2004, 32 (12) 1333-1336; DOI: https://doi.org/10.1124/dmd.104.001164

  5. Chen, Chuan

    1. TISSUE DISTRIBUTION OF CONCENTRATIVE AND EQUILIBRATIVE NUCLEOSIDE TRANSPORTERS IN MALE AND FEMALE RATS AND MICE
      Hong Lu, Chuan Chen and Curtis Klaassen
      Drug Metabolism and Disposition December 2004, 32 (12) 1455-1461; DOI: https://doi.org/10.1124/dmd.104.001123

  6. Cho, Joo-Youn

    1. HAPLOTYPE STRUCTURE AND ALLELE FREQUENCIES OF CYP2B6 IN A KOREAN POPULATION
      Joo-Youn Cho, Hyeong-Seok Lim, Jae-Yong Chung, Kyung-Sang Yu, Jung-Ryul Kim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition December 2004, 32 (12) 1341-1344; DOI: https://doi.org/10.1124/dmd.104.001107

  7. Christ, David D.

    1. THE CHIMPANZEE (PAN TROGLODYTES) AS A PHARMACOKINETIC MODEL FOR SELECTION OF DRUG CANDIDATES: MODEL CHARACTERIZATION AND APPLICATION
      Harvey Wong, Scott J. Grossman, Stephen A. Bai, Sharon Diamond, Matthew R. Wright, James E. Grace, Mingxin Qian, Kan He, Krishnaswamy Yeleswaram and David D. Christ
      Drug Metabolism and Disposition December 2004, 32 (12) 1359-1369; DOI: https://doi.org/10.1124/dmd.104.000943

  8. Chung, Jae-Yong

    1. HAPLOTYPE STRUCTURE AND ALLELE FREQUENCIES OF CYP2B6 IN A KOREAN POPULATION
      Joo-Youn Cho, Hyeong-Seok Lim, Jae-Yong Chung, Kyung-Sang Yu, Jung-Ryul Kim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition December 2004, 32 (12) 1341-1344; DOI: https://doi.org/10.1124/dmd.104.001107

  9. Claes, Kathleen

    1. THE RATE OF GASTRIC EMPTYING DETERMINES THE TIMING BUT NOT THE EXTENT OF ORAL TACROLIMUS ABSORPTION: SIMULTANEOUS MEASUREMENT OF DRUG EXPOSURE AND GASTRIC EMPTYING BY CARBON-14-OCTANOIC ACID BREATH TEST IN STABLE RENAL ALLOGRAFT RECIPIENTS
      Dirk R. J. Kuypers, Kathleen Claes, P. Evenepoel, B. Maes and Yves Vanrenterghem
      Drug Metabolism and Disposition December 2004, 32 (12) 1421-1425; DOI: https://doi.org/10.1124/dmd.104.001503

D

  1. D'Antoni, Michelle

    1. USE OF A BENZYLOXY-SUBSTITUTED LACTONE CYCLOOXYGENASE-2 INHIBITOR AS A SELECTIVE FLUORESCENT PROBE FOR CYP3A ACTIVITY IN PRIMARY CULTURED RAT AND HUMAN HEPATOCYTES
      Deborah A. Nicoll-Griffith, Nathalie Chauret, Robert Houle, Stephen H. Day, Michelle D'Antoni and José M. Silva
      Drug Metabolism and Disposition December 2004, 32 (12) 1509-1515; DOI: https://doi.org/10.1124/dmd.32.12.1509

  2. Day, Stephen H.

    1. USE OF A BENZYLOXY-SUBSTITUTED LACTONE CYCLOOXYGENASE-2 INHIBITOR AS A SELECTIVE FLUORESCENT PROBE FOR CYP3A ACTIVITY IN PRIMARY CULTURED RAT AND HUMAN HEPATOCYTES
      Deborah A. Nicoll-Griffith, Nathalie Chauret, Robert Houle, Stephen H. Day, Michelle D'Antoni and José M. Silva
      Drug Metabolism and Disposition December 2004, 32 (12) 1509-1515; DOI: https://doi.org/10.1124/dmd.32.12.1509

  3. DeLegge, Mark H.

    1. HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS
      Thomas Walle, Faye Hsieh, Mark H. DeLegge, John E. Oatis and U. Kristina Walle
      Drug Metabolism and Disposition December 2004, 32 (12) 1377-1382; DOI: https://doi.org/10.1124/dmd.104.000885

  4. DeVane, C. Lindsay

    1. MULTIPLE NIGHT-TIME DOSES OF VALERIAN (Valeriana officinalis) HAD MINIMAL EFFECTS ON CYP3A4 ACTIVITY AND NO EFFECT ON CYP2D6 ACTIVITY IN HEALTHY VOLUNTEERS
      Jennifer L. Donovan, C. Lindsay DeVane, Kenneth D. Chavin, Jun-Sheng Wang, Bryan B. Gibson, Holly A. Gefroh and John S. Markowitz
      Drug Metabolism and Disposition December 2004, 32 (12) 1333-1336; DOI: https://doi.org/10.1124/dmd.104.001164

  5. Diamond, Sharon

    1. THE CHIMPANZEE (PAN TROGLODYTES) AS A PHARMACOKINETIC MODEL FOR SELECTION OF DRUG CANDIDATES: MODEL CHARACTERIZATION AND APPLICATION
      Harvey Wong, Scott J. Grossman, Stephen A. Bai, Sharon Diamond, Matthew R. Wright, James E. Grace, Mingxin Qian, Kan He, Krishnaswamy Yeleswaram and David D. Christ
      Drug Metabolism and Disposition December 2004, 32 (12) 1359-1369; DOI: https://doi.org/10.1124/dmd.104.000943

  6. Ding, Xinxin

    1. IDENTIFICATION OF CRITICAL AMINO ACID RESIDUES OF HUMAN CYP2A13 FOR THE METABOLIC ACTIVATION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE, A TOBACCO-SPECIFIC CARCINOGEN
      Xiao-Yang He, Jian Shen, Xinxin Ding, Anthony Y. H. Lu and Jun-Yan Hong
      Drug Metabolism and Disposition December 2004, 32 (12) 1516-1521; DOI: https://doi.org/10.1124/dmd.104.001370

  7. Donovan, Jennifer L.

    1. MULTIPLE NIGHT-TIME DOSES OF VALERIAN (Valeriana officinalis) HAD MINIMAL EFFECTS ON CYP3A4 ACTIVITY AND NO EFFECT ON CYP2D6 ACTIVITY IN HEALTHY VOLUNTEERS
      Jennifer L. Donovan, C. Lindsay DeVane, Kenneth D. Chavin, Jun-Sheng Wang, Bryan B. Gibson, Holly A. Gefroh and John S. Markowitz
      Drug Metabolism and Disposition December 2004, 32 (12) 1333-1336; DOI: https://doi.org/10.1124/dmd.104.001164

  8. Duffel, Michael W.

    1. INTERACTIONS OF THE STEREOISOMERS OF α-HYDROXYTAMOXIFEN WITH HUMAN HYDROXYSTEROID SULFOTRANSFERASE SULT2A1 AND RAT HYDROXYSTEROID SULFOTRANSFERASE STA
      T. Idil Apak and Michael W. Duffel
      Drug Metabolism and Disposition December 2004, 32 (12) 1501-1508; DOI: https://doi.org/10.1124/dmd.104.000919

E

  1. Elovaara, Eivor

    1. ASSESSMENT OF CATECHOL INDUCTION AND GLUCURONIDATION IN RAT LIVER MICROSOMES
      Eivor Elovaara, Jouni Mikkola, Leena Luukkanen, Laurence Antonio, Sylvie Fournel-Gigleux, Brian Burchell, Jacques Magdalou and Jyrki Taskinen
      Drug Metabolism and Disposition December 2004, 32 (12) 1426-1433; DOI: https://doi.org/10.1124/dmd.104.000992

  2. Ericsson, Hans

    1. RESPONSE: PREDICTING THE CLEARANCE OF CYP2C9 SUBSTRATES
      Tommy B. Andersson, Eva Bredberg, Hans Ericsson and Helena SjÖberg
      Drug Metabolism and Disposition December 2004, 32 (12) 1523; DOI: https://doi.org/10.1124/dmd.104.002329

  3. Evenepoel, P.

    1. THE RATE OF GASTRIC EMPTYING DETERMINES THE TIMING BUT NOT THE EXTENT OF ORAL TACROLIMUS ABSORPTION: SIMULTANEOUS MEASUREMENT OF DRUG EXPOSURE AND GASTRIC EMPTYING BY CARBON-14-OCTANOIC ACID BREATH TEST IN STABLE RENAL ALLOGRAFT RECIPIENTS
      Dirk R. J. Kuypers, Kathleen Claes, P. Evenepoel, B. Maes and Yves Vanrenterghem
      Drug Metabolism and Disposition December 2004, 32 (12) 1421-1425; DOI: https://doi.org/10.1124/dmd.104.001503

F

  1. Fitch, William L.

    1. IDENTIFICATION OF GLUTATHIONE-DERIVED METABOLITES FROM AN IP RECEPTOR ANTAGONIST
      William L. Fitch, Pamela W. Berry, Yaping Tu, Ali Tabatabaei, Lee Lowrie, Francisco Lopez-Tapia, Yanzhou Liu, Dov Nitzan, Mohammad R. Masjedizadeh and Aravamuthan Varadarajan
      Drug Metabolism and Disposition December 2004, 32 (12) 1482-1490; DOI: https://doi.org/10.1124/dmd.104.000471

  2. Fournel-Gigleux, Sylvie

    1. ASSESSMENT OF CATECHOL INDUCTION AND GLUCURONIDATION IN RAT LIVER MICROSOMES
      Eivor Elovaara, Jouni Mikkola, Leena Luukkanen, Laurence Antonio, Sylvie Fournel-Gigleux, Brian Burchell, Jacques Magdalou and Jyrki Taskinen
      Drug Metabolism and Disposition December 2004, 32 (12) 1426-1433; DOI: https://doi.org/10.1124/dmd.104.000992

G

  1. Galetin, Aleksandra

    1. UTILITY OF RECOMBINANT ENZYME KINETICS IN PREDICTION OF HUMAN CLEARANCE: IMPACT OF VARIABILITY, CYP3A5, AND CYP2C19 ON CYP3A4 PROBE SUBSTRATES
      Aleksandra Galetin, Caroline Brown, David Hallifax, Kiyomi Ito and J. Brian Houston
      Drug Metabolism and Disposition December 2004, 32 (12) 1411-1420; DOI: https://doi.org/10.1124/dmd.104.000844

  2. Gefroh, Holly A.

    1. MULTIPLE NIGHT-TIME DOSES OF VALERIAN (Valeriana officinalis) HAD MINIMAL EFFECTS ON CYP3A4 ACTIVITY AND NO EFFECT ON CYP2D6 ACTIVITY IN HEALTHY VOLUNTEERS
      Jennifer L. Donovan, C. Lindsay DeVane, Kenneth D. Chavin, Jun-Sheng Wang, Bryan B. Gibson, Holly A. Gefroh and John S. Markowitz
      Drug Metabolism and Disposition December 2004, 32 (12) 1333-1336; DOI: https://doi.org/10.1124/dmd.104.001164

  3. Ghoborah, Hesham

    1. METABOLISM AND DISPOSITION OF CALCIMIMETIC AGENT CINACALCET HCL IN HUMANS AND ANIMAL MODELS
      Gondi N. Kumar, Christopher Sproul, Leszek Poppe, Sharon Turner, Mark Gohdes, Hesham Ghoborah, Desmond Padhi and Lorin Roskos
      Drug Metabolism and Disposition December 2004, 32 (12) 1491-1500; DOI: https://doi.org/10.1124/dmd.104.000604

  4. Gibson, Bryan B.

    1. MULTIPLE NIGHT-TIME DOSES OF VALERIAN (Valeriana officinalis) HAD MINIMAL EFFECTS ON CYP3A4 ACTIVITY AND NO EFFECT ON CYP2D6 ACTIVITY IN HEALTHY VOLUNTEERS
      Jennifer L. Donovan, C. Lindsay DeVane, Kenneth D. Chavin, Jun-Sheng Wang, Bryan B. Gibson, Holly A. Gefroh and John S. Markowitz
      Drug Metabolism and Disposition December 2004, 32 (12) 1333-1336; DOI: https://doi.org/10.1124/dmd.104.001164

  5. Gibson, Gordon

    1. EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
      Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
      Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208

  6. Gilbert, Darryl

    1. EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
      Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
      Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208

  7. Glodowski, Mary

    1. EVIDENCE OF SIGNIFICANT CONTRIBUTION FROM CYP3A5 TO HEPATIC DRUG METABOLISM
      Weili Huang, Yvonne S. Lin, Donavon J. McConn, Justina C. Calamia, Rheem A. Totah, Nina Isoherranen, Mary Glodowski and Kenneth E. Thummel
      Drug Metabolism and Disposition December 2004, 32 (12) 1434-1445; DOI: https://doi.org/10.1124/dmd.104.001313

  8. Gohdes, Mark

    1. METABOLISM AND DISPOSITION OF CALCIMIMETIC AGENT CINACALCET HCL IN HUMANS AND ANIMAL MODELS
      Gondi N. Kumar, Christopher Sproul, Leszek Poppe, Sharon Turner, Mark Gohdes, Hesham Ghoborah, Desmond Padhi and Lorin Roskos
      Drug Metabolism and Disposition December 2004, 32 (12) 1491-1500; DOI: https://doi.org/10.1124/dmd.104.000604

  9. Grace, James E.

    1. THE CHIMPANZEE (PAN TROGLODYTES) AS A PHARMACOKINETIC MODEL FOR SELECTION OF DRUG CANDIDATES: MODEL CHARACTERIZATION AND APPLICATION
      Harvey Wong, Scott J. Grossman, Stephen A. Bai, Sharon Diamond, Matthew R. Wright, James E. Grace, Mingxin Qian, Kan He, Krishnaswamy Yeleswaram and David D. Christ
      Drug Metabolism and Disposition December 2004, 32 (12) 1359-1369; DOI: https://doi.org/10.1124/dmd.104.000943

  10. Grossman, Scott J.

    1. THE CHIMPANZEE (PAN TROGLODYTES) AS A PHARMACOKINETIC MODEL FOR SELECTION OF DRUG CANDIDATES: MODEL CHARACTERIZATION AND APPLICATION
      Harvey Wong, Scott J. Grossman, Stephen A. Bai, Sharon Diamond, Matthew R. Wright, James E. Grace, Mingxin Qian, Kan He, Krishnaswamy Yeleswaram and David D. Christ
      Drug Metabolism and Disposition December 2004, 32 (12) 1359-1369; DOI: https://doi.org/10.1124/dmd.104.000943

H

  1. Hallifax, David

    1. UTILITY OF RECOMBINANT ENZYME KINETICS IN PREDICTION OF HUMAN CLEARANCE: IMPACT OF VARIABILITY, CYP3A5, AND CYP2C19 ON CYP3A4 PROBE SUBSTRATES
      Aleksandra Galetin, Caroline Brown, David Hallifax, Kiyomi Ito and J. Brian Houston
      Drug Metabolism and Disposition December 2004, 32 (12) 1411-1420; DOI: https://doi.org/10.1124/dmd.104.000844

  2. He, Kan

    1. THE CHIMPANZEE (PAN TROGLODYTES) AS A PHARMACOKINETIC MODEL FOR SELECTION OF DRUG CANDIDATES: MODEL CHARACTERIZATION AND APPLICATION
      Harvey Wong, Scott J. Grossman, Stephen A. Bai, Sharon Diamond, Matthew R. Wright, James E. Grace, Mingxin Qian, Kan He, Krishnaswamy Yeleswaram and David D. Christ
      Drug Metabolism and Disposition December 2004, 32 (12) 1359-1369; DOI: https://doi.org/10.1124/dmd.104.000943

  3. He, Xiao-Yang

    1. IDENTIFICATION OF CRITICAL AMINO ACID RESIDUES OF HUMAN CYP2A13 FOR THE METABOLIC ACTIVATION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE, A TOBACCO-SPECIFIC CARCINOGEN
      Xiao-Yang He, Jian Shen, Xinxin Ding, Anthony Y. H. Lu and Jun-Yan Hong
      Drug Metabolism and Disposition December 2004, 32 (12) 1516-1521; DOI: https://doi.org/10.1124/dmd.104.001370

  4. Hines, Ronald N.

    1. DIFFERENCES IN FMO2*1 ALLELIC FREQUENCY BETWEEN HISPANICS OF PUERTO RICAN AND MEXICAN DESCENT
      Sharon K. Krueger, Lisbeth K. Siddens, Sarah R. Martin, Zhen Yu, Clifford B. Pereira, Erwin T. Cabacungan, Ronald N. Hines, Kristin G. Ardlie, Judy L. Raucy and David E. Williams
      Drug Metabolism and Disposition December 2004, 32 (12) 1337-1340; DOI: https://doi.org/10.1124/dmd.104.001099

  5. Hirani, Vandana N.

    1. CONVERSION OF THE HIV PROTEASE INHIBITOR NELFINAVIR TO A BIOACTIVE METABOLITE BY HUMAN LIVER CYP2C19
      Vandana N. Hirani, Judy L. Raucy and Jerome M. Lasker
      Drug Metabolism and Disposition December 2004, 32 (12) 1462-1467; DOI: https://doi.org/10.1124/dmd.104.001743

  6. Hirano, Masaru

    1. IN VITRO AND IN VIVO CORRELATION OF THE INHIBITORY EFFECT OF CYCLOSPORIN A ON THE TRANSPORTER-MEDIATED HEPATIC UPTAKE OF CERIVASTATIN IN RATS
      Yoshihisa Shitara, Masaru Hirano, Yasuhisa Adachi, Tomoo Itoh, Hitoshi Sato and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2004, 32 (12) 1468-1475; DOI: https://doi.org/10.1124/dmd.32.12.1468

  7. Hiratsuka, Akira

    1. IDENTIFICATION AND CHARACTERIZATION OF POTENT CYP3A4 INHIBITORS IN SCHISANDRA FRUIT EXTRACT
      Hiroshi Iwata, Yasuhiro Tezuka, Shigetoshi Kadota, Akira Hiratsuka and Tadashi Watabe
      Drug Metabolism and Disposition December 2004, 32 (12) 1351-1358; DOI: https://doi.org/10.1124/dmd.104.000646

  8. Hong, Jun-Yan

    1. IDENTIFICATION OF CRITICAL AMINO ACID RESIDUES OF HUMAN CYP2A13 FOR THE METABOLIC ACTIVATION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE, A TOBACCO-SPECIFIC CARCINOGEN
      Xiao-Yang He, Jian Shen, Xinxin Ding, Anthony Y. H. Lu and Jun-Yan Hong
      Drug Metabolism and Disposition December 2004, 32 (12) 1516-1521; DOI: https://doi.org/10.1124/dmd.104.001370

  9. Horie, Toru

    1. EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Miho Kataoka, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2004, 32 (12) 1402-1410; DOI: https://doi.org/10.1124/dmd.104.001347

  10. Hose, Curtis D.

    1. FLUORINATED 2-(4-AMINO-3-METHYLPHENYL)BENZOTHIAZOLES INDUCE CYP1A1 EXPRESSION, BECOME METABOLIZED, AND BIND TO MACROMOLECULES IN SENSITIVE HUMAN CANCER CELLS
      Eileen Brantley, Valentina Trapani, Michael C. Alley, Curtis D. Hose, Tracey D. Bradshaw, Malcolm F. G. Stevens, Edward A. Sausville and Sherman F. Stinson
      Drug Metabolism and Disposition December 2004, 32 (12) 1392-1401; DOI: https://doi.org/10.1124/dmd.104.001057

  11. Houle, Robert

    1. USE OF A BENZYLOXY-SUBSTITUTED LACTONE CYCLOOXYGENASE-2 INHIBITOR AS A SELECTIVE FLUORESCENT PROBE FOR CYP3A ACTIVITY IN PRIMARY CULTURED RAT AND HUMAN HEPATOCYTES
      Deborah A. Nicoll-Griffith, Nathalie Chauret, Robert Houle, Stephen H. Day, Michelle D'Antoni and José M. Silva
      Drug Metabolism and Disposition December 2004, 32 (12) 1509-1515; DOI: https://doi.org/10.1124/dmd.32.12.1509

  12. Houston, J. Brian

    1. UTILITY OF RECOMBINANT ENZYME KINETICS IN PREDICTION OF HUMAN CLEARANCE: IMPACT OF VARIABILITY, CYP3A5, AND CYP2C19 ON CYP3A4 PROBE SUBSTRATES
      Aleksandra Galetin, Caroline Brown, David Hallifax, Kiyomi Ito and J. Brian Houston
      Drug Metabolism and Disposition December 2004, 32 (12) 1411-1420; DOI: https://doi.org/10.1124/dmd.104.000844

  13. Howgate, Eleanor M.

    1. PREDICTING THE CLEARANCE OF CYP2C9 SUBSTRATES
      Karen Rowland Yeo, Eleanor M. Howgate, Geoffrey T. Tucker and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition December 2004, 32 (12) 1522; DOI: https://doi.org/10.1124/dmd.104.001792

  14. Hsieh, Faye

    1. HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS
      Thomas Walle, Faye Hsieh, Mark H. DeLegge, John E. Oatis and U. Kristina Walle
      Drug Metabolism and Disposition December 2004, 32 (12) 1377-1382; DOI: https://doi.org/10.1124/dmd.104.000885

  15. Huang, Weili

    1. EVIDENCE OF SIGNIFICANT CONTRIBUTION FROM CYP3A5 TO HEPATIC DRUG METABOLISM
      Weili Huang, Yvonne S. Lin, Donavon J. McConn, Justina C. Calamia, Rheem A. Totah, Nina Isoherranen, Mary Glodowski and Kenneth E. Thummel
      Drug Metabolism and Disposition December 2004, 32 (12) 1434-1445; DOI: https://doi.org/10.1124/dmd.104.001313

I

  1. Inagaki, Haruhisa

    1. MECHANISM OF THE DRUG INTERACTION BETWEEN VALPROIC ACID AND CARBAPENEM ANTIBIOTICS IN MONKEYS AND RATS
      Yoshitsugu Nakajima, Minoru Mizobuchi, Masahiro Nakamura, Hidetoshi Takagi, Haruhisa Inagaki, Goro Kominami, Masahiro Koike and Toshiro Yamaguchi
      Drug Metabolism and Disposition December 2004, 32 (12) 1383-1391; DOI: https://doi.org/10.1124/dmd.104.000661

  2. Isoherranen, Nina

    1. EVIDENCE OF SIGNIFICANT CONTRIBUTION FROM CYP3A5 TO HEPATIC DRUG METABOLISM
      Weili Huang, Yvonne S. Lin, Donavon J. McConn, Justina C. Calamia, Rheem A. Totah, Nina Isoherranen, Mary Glodowski and Kenneth E. Thummel
      Drug Metabolism and Disposition December 2004, 32 (12) 1434-1445; DOI: https://doi.org/10.1124/dmd.104.001313

  3. Ito, Kiyomi

    1. UTILITY OF RECOMBINANT ENZYME KINETICS IN PREDICTION OF HUMAN CLEARANCE: IMPACT OF VARIABILITY, CYP3A5, AND CYP2C19 ON CYP3A4 PROBE SUBSTRATES
      Aleksandra Galetin, Caroline Brown, David Hallifax, Kiyomi Ito and J. Brian Houston
      Drug Metabolism and Disposition December 2004, 32 (12) 1411-1420; DOI: https://doi.org/10.1124/dmd.104.000844

  4. Itoh, Tomoo

    1. IN VITRO AND IN VIVO CORRELATION OF THE INHIBITORY EFFECT OF CYCLOSPORIN A ON THE TRANSPORTER-MEDIATED HEPATIC UPTAKE OF CERIVASTATIN IN RATS
      Yoshihisa Shitara, Masaru Hirano, Yasuhisa Adachi, Tomoo Itoh, Hitoshi Sato and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2004, 32 (12) 1468-1475; DOI: https://doi.org/10.1124/dmd.32.12.1468

  5. Iwasaki, Kazuhide

    1. EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Miho Kataoka, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2004, 32 (12) 1402-1410; DOI: https://doi.org/10.1124/dmd.104.001347

  6. Iwata, Hiroshi

    1. IDENTIFICATION AND CHARACTERIZATION OF POTENT CYP3A4 INHIBITORS IN SCHISANDRA FRUIT EXTRACT
      Hiroshi Iwata, Yasuhiro Tezuka, Shigetoshi Kadota, Akira Hiratsuka and Tadashi Watabe
      Drug Metabolism and Disposition December 2004, 32 (12) 1351-1358; DOI: https://doi.org/10.1124/dmd.104.000646

J

  1. Jang, In-Jin

    1. HAPLOTYPE STRUCTURE AND ALLELE FREQUENCIES OF CYP2B6 IN A KOREAN POPULATION
      Joo-Youn Cho, Hyeong-Seok Lim, Jae-Yong Chung, Kyung-Sang Yu, Jung-Ryul Kim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition December 2004, 32 (12) 1341-1344; DOI: https://doi.org/10.1124/dmd.104.001107

  2. Jolley, Summer

    1. EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
      Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
      Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208

K

  1. Kadota, Shigetoshi

    1. IDENTIFICATION AND CHARACTERIZATION OF POTENT CYP3A4 INHIBITORS IN SCHISANDRA FRUIT EXTRACT
      Hiroshi Iwata, Yasuhiro Tezuka, Shigetoshi Kadota, Akira Hiratsuka and Tadashi Watabe
      Drug Metabolism and Disposition December 2004, 32 (12) 1351-1358; DOI: https://doi.org/10.1124/dmd.104.000646

  2. Kataoka, Miho

    1. EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Miho Kataoka, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2004, 32 (12) 1402-1410; DOI: https://doi.org/10.1124/dmd.104.001347

  3. Katoh, Miki

    1. EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Miho Kataoka, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2004, 32 (12) 1402-1410; DOI: https://doi.org/10.1124/dmd.104.001347

  4. Kim, Jung-Ryul

    1. HAPLOTYPE STRUCTURE AND ALLELE FREQUENCIES OF CYP2B6 IN A KOREAN POPULATION
      Joo-Youn Cho, Hyeong-Seok Lim, Jae-Yong Chung, Kyung-Sang Yu, Jung-Ryul Kim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition December 2004, 32 (12) 1341-1344; DOI: https://doi.org/10.1124/dmd.104.001107

  5. Klaassen, Curtis

    1. TISSUE DISTRIBUTION OF CONCENTRATIVE AND EQUILIBRATIVE NUCLEOSIDE TRANSPORTERS IN MALE AND FEMALE RATS AND MICE
      Hong Lu, Chuan Chen and Curtis Klaassen
      Drug Metabolism and Disposition December 2004, 32 (12) 1455-1461; DOI: https://doi.org/10.1124/dmd.104.001123

  6. Koike, Masahiro

    1. MECHANISM OF THE DRUG INTERACTION BETWEEN VALPROIC ACID AND CARBAPENEM ANTIBIOTICS IN MONKEYS AND RATS
      Yoshitsugu Nakajima, Minoru Mizobuchi, Masahiro Nakamura, Hidetoshi Takagi, Haruhisa Inagaki, Goro Kominami, Masahiro Koike and Toshiro Yamaguchi
      Drug Metabolism and Disposition December 2004, 32 (12) 1383-1391; DOI: https://doi.org/10.1124/dmd.104.000661

  7. Kole, L.

    1. RESPONSE TO THE LETTER TO THE EDITOR BY DRS. N. PICARD AND P. MARQUET REGARDING A PUBLICATION: BASU ET AL., DRUG METABOLISM AND DISPOSITION (32:768–773, (2004)
      N. K. Basu, L. Kole, S. Kubota and I. S. Owens
      Drug Metabolism and Disposition December 2004, 32 (12) 1525; DOI: https://doi.org/10.1124/dmd.104.002345

  8. Kominami, Goro

    1. MECHANISM OF THE DRUG INTERACTION BETWEEN VALPROIC ACID AND CARBAPENEM ANTIBIOTICS IN MONKEYS AND RATS
      Yoshitsugu Nakajima, Minoru Mizobuchi, Masahiro Nakamura, Hidetoshi Takagi, Haruhisa Inagaki, Goro Kominami, Masahiro Koike and Toshiro Yamaguchi
      Drug Metabolism and Disposition December 2004, 32 (12) 1383-1391; DOI: https://doi.org/10.1124/dmd.104.000661

  9. Krueger, Sharon K.

    1. DIFFERENCES IN FMO2*1 ALLELIC FREQUENCY BETWEEN HISPANICS OF PUERTO RICAN AND MEXICAN DESCENT
      Sharon K. Krueger, Lisbeth K. Siddens, Sarah R. Martin, Zhen Yu, Clifford B. Pereira, Erwin T. Cabacungan, Ronald N. Hines, Kristin G. Ardlie, Judy L. Raucy and David E. Williams
      Drug Metabolism and Disposition December 2004, 32 (12) 1337-1340; DOI: https://doi.org/10.1124/dmd.104.001099

  10. Kubota, S.

    1. RESPONSE TO THE LETTER TO THE EDITOR BY DRS. N. PICARD AND P. MARQUET REGARDING A PUBLICATION: BASU ET AL., DRUG METABOLISM AND DISPOSITION (32:768–773, (2004)
      N. K. Basu, L. Kole, S. Kubota and I. S. Owens
      Drug Metabolism and Disposition December 2004, 32 (12) 1525; DOI: https://doi.org/10.1124/dmd.104.002345

  11. Kumar, Gondi N.

    1. METABOLISM AND DISPOSITION OF CALCIMIMETIC AGENT CINACALCET HCL IN HUMANS AND ANIMAL MODELS
      Gondi N. Kumar, Christopher Sproul, Leszek Poppe, Sharon Turner, Mark Gohdes, Hesham Ghoborah, Desmond Padhi and Lorin Roskos
      Drug Metabolism and Disposition December 2004, 32 (12) 1491-1500; DOI: https://doi.org/10.1124/dmd.104.000604

  12. Kuypers, Dirk R. J.

    1. THE RATE OF GASTRIC EMPTYING DETERMINES THE TIMING BUT NOT THE EXTENT OF ORAL TACROLIMUS ABSORPTION: SIMULTANEOUS MEASUREMENT OF DRUG EXPOSURE AND GASTRIC EMPTYING BY CARBON-14-OCTANOIC ACID BREATH TEST IN STABLE RENAL ALLOGRAFT RECIPIENTS
      Dirk R. J. Kuypers, Kathleen Claes, P. Evenepoel, B. Maes and Yves Vanrenterghem
      Drug Metabolism and Disposition December 2004, 32 (12) 1421-1425; DOI: https://doi.org/10.1124/dmd.104.001503

L

  1. Lasker, Jerome M.

    1. CONVERSION OF THE HIV PROTEASE INHIBITOR NELFINAVIR TO A BIOACTIVE METABOLITE BY HUMAN LIVER CYP2C19
      Vandana N. Hirani, Judy L. Raucy and Jerome M. Lasker
      Drug Metabolism and Disposition December 2004, 32 (12) 1462-1467; DOI: https://doi.org/10.1124/dmd.104.001743

  2. LeCluyse, Edward L.

    1. EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
      Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
      Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208

  3. Lim, Hyeong-Seok

    1. HAPLOTYPE STRUCTURE AND ALLELE FREQUENCIES OF CYP2B6 IN A KOREAN POPULATION
      Joo-Youn Cho, Hyeong-Seok Lim, Jae-Yong Chung, Kyung-Sang Yu, Jung-Ryul Kim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition December 2004, 32 (12) 1341-1344; DOI: https://doi.org/10.1124/dmd.104.001107

  4. Lin, Yvonne S.

    1. EVIDENCE OF SIGNIFICANT CONTRIBUTION FROM CYP3A5 TO HEPATIC DRUG METABOLISM
      Weili Huang, Yvonne S. Lin, Donavon J. McConn, Justina C. Calamia, Rheem A. Totah, Nina Isoherranen, Mary Glodowski and Kenneth E. Thummel
      Drug Metabolism and Disposition December 2004, 32 (12) 1434-1445; DOI: https://doi.org/10.1124/dmd.104.001313

  5. Liu, Yanzhou

    1. IDENTIFICATION OF GLUTATHIONE-DERIVED METABOLITES FROM AN IP RECEPTOR ANTAGONIST
      William L. Fitch, Pamela W. Berry, Yaping Tu, Ali Tabatabaei, Lee Lowrie, Francisco Lopez-Tapia, Yanzhou Liu, Dov Nitzan, Mohammad R. Masjedizadeh and Aravamuthan Varadarajan
      Drug Metabolism and Disposition December 2004, 32 (12) 1482-1490; DOI: https://doi.org/10.1124/dmd.104.000471

  6. Lopez-Tapia, Francisco

    1. IDENTIFICATION OF GLUTATHIONE-DERIVED METABOLITES FROM AN IP RECEPTOR ANTAGONIST
      William L. Fitch, Pamela W. Berry, Yaping Tu, Ali Tabatabaei, Lee Lowrie, Francisco Lopez-Tapia, Yanzhou Liu, Dov Nitzan, Mohammad R. Masjedizadeh and Aravamuthan Varadarajan
      Drug Metabolism and Disposition December 2004, 32 (12) 1482-1490; DOI: https://doi.org/10.1124/dmd.104.000471

  7. Lowrie, Lee

    1. IDENTIFICATION OF GLUTATHIONE-DERIVED METABOLITES FROM AN IP RECEPTOR ANTAGONIST
      William L. Fitch, Pamela W. Berry, Yaping Tu, Ali Tabatabaei, Lee Lowrie, Francisco Lopez-Tapia, Yanzhou Liu, Dov Nitzan, Mohammad R. Masjedizadeh and Aravamuthan Varadarajan
      Drug Metabolism and Disposition December 2004, 32 (12) 1482-1490; DOI: https://doi.org/10.1124/dmd.104.000471

  8. Lu, Anthony Y. H.

    1. IDENTIFICATION OF CRITICAL AMINO ACID RESIDUES OF HUMAN CYP2A13 FOR THE METABOLIC ACTIVATION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE, A TOBACCO-SPECIFIC CARCINOGEN
      Xiao-Yang He, Jian Shen, Xinxin Ding, Anthony Y. H. Lu and Jun-Yan Hong
      Drug Metabolism and Disposition December 2004, 32 (12) 1516-1521; DOI: https://doi.org/10.1124/dmd.104.001370

  9. Lu, Hong

    1. TISSUE DISTRIBUTION OF CONCENTRATIVE AND EQUILIBRATIVE NUCLEOSIDE TRANSPORTERS IN MALE AND FEMALE RATS AND MICE
      Hong Lu, Chuan Chen and Curtis Klaassen
      Drug Metabolism and Disposition December 2004, 32 (12) 1455-1461; DOI: https://doi.org/10.1124/dmd.104.001123

  10. Luukkanen, Leena

    1. ASSESSMENT OF CATECHOL INDUCTION AND GLUCURONIDATION IN RAT LIVER MICROSOMES
      Eivor Elovaara, Jouni Mikkola, Leena Luukkanen, Laurence Antonio, Sylvie Fournel-Gigleux, Brian Burchell, Jacques Magdalou and Jyrki Taskinen
      Drug Metabolism and Disposition December 2004, 32 (12) 1426-1433; DOI: https://doi.org/10.1124/dmd.104.000992

M

  1. Maes, B.

    1. THE RATE OF GASTRIC EMPTYING DETERMINES THE TIMING BUT NOT THE EXTENT OF ORAL TACROLIMUS ABSORPTION: SIMULTANEOUS MEASUREMENT OF DRUG EXPOSURE AND GASTRIC EMPTYING BY CARBON-14-OCTANOIC ACID BREATH TEST IN STABLE RENAL ALLOGRAFT RECIPIENTS
      Dirk R. J. Kuypers, Kathleen Claes, P. Evenepoel, B. Maes and Yves Vanrenterghem
      Drug Metabolism and Disposition December 2004, 32 (12) 1421-1425; DOI: https://doi.org/10.1124/dmd.104.001503

  2. Magdalou, Jacques

    1. ASSESSMENT OF CATECHOL INDUCTION AND GLUCURONIDATION IN RAT LIVER MICROSOMES
      Eivor Elovaara, Jouni Mikkola, Leena Luukkanen, Laurence Antonio, Sylvie Fournel-Gigleux, Brian Burchell, Jacques Magdalou and Jyrki Taskinen
      Drug Metabolism and Disposition December 2004, 32 (12) 1426-1433; DOI: https://doi.org/10.1124/dmd.104.000992

  3. Markowitz, John S.

    1. MULTIPLE NIGHT-TIME DOSES OF VALERIAN (Valeriana officinalis) HAD MINIMAL EFFECTS ON CYP3A4 ACTIVITY AND NO EFFECT ON CYP2D6 ACTIVITY IN HEALTHY VOLUNTEERS
      Jennifer L. Donovan, C. Lindsay DeVane, Kenneth D. Chavin, Jun-Sheng Wang, Bryan B. Gibson, Holly A. Gefroh and John S. Markowitz
      Drug Metabolism and Disposition December 2004, 32 (12) 1333-1336; DOI: https://doi.org/10.1124/dmd.104.001164

  4. Marquet, Pierre

    1. IN VITRO STUDY OF MYCOPHENOLIC ACID GLUCURONIDATION
      Nicolas Picard and Pierre Marquet
      Drug Metabolism and Disposition December 2004, 32 (12) 1524; DOI: https://doi.org/10.1124/dmd.104.001982

  5. Martin, Sarah R.

    1. DIFFERENCES IN FMO2*1 ALLELIC FREQUENCY BETWEEN HISPANICS OF PUERTO RICAN AND MEXICAN DESCENT
      Sharon K. Krueger, Lisbeth K. Siddens, Sarah R. Martin, Zhen Yu, Clifford B. Pereira, Erwin T. Cabacungan, Ronald N. Hines, Kristin G. Ardlie, Judy L. Raucy and David E. Williams
      Drug Metabolism and Disposition December 2004, 32 (12) 1337-1340; DOI: https://doi.org/10.1124/dmd.104.001099

  6. Masjedizadeh, Mohammad R.

    1. IDENTIFICATION OF GLUTATHIONE-DERIVED METABOLITES FROM AN IP RECEPTOR ANTAGONIST
      William L. Fitch, Pamela W. Berry, Yaping Tu, Ali Tabatabaei, Lee Lowrie, Francisco Lopez-Tapia, Yanzhou Liu, Dov Nitzan, Mohammad R. Masjedizadeh and Aravamuthan Varadarajan
      Drug Metabolism and Disposition December 2004, 32 (12) 1482-1490; DOI: https://doi.org/10.1124/dmd.104.000471

  7. Matsui, Tomohito

    1. EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Miho Kataoka, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2004, 32 (12) 1402-1410; DOI: https://doi.org/10.1124/dmd.104.001347

  8. McConn, Donavon J.

    1. EVIDENCE OF SIGNIFICANT CONTRIBUTION FROM CYP3A5 TO HEPATIC DRUG METABOLISM
      Weili Huang, Yvonne S. Lin, Donavon J. McConn, Justina C. Calamia, Rheem A. Totah, Nina Isoherranen, Mary Glodowski and Kenneth E. Thummel
      Drug Metabolism and Disposition December 2004, 32 (12) 1434-1445; DOI: https://doi.org/10.1124/dmd.104.001313

  9. Mehvar, Reza

    1. SHORT-TERM INHIBITORY EFFECTS OF NITRIC OXIDE ON CYTOCHROME P450-MEDIATED DRUG METABOLISM: TIME DEPENDENCY AND REVERSIBILITY PROFILES IN ISOLATED PERFUSED RAT LIVERS
      Ragini Vuppugalla and Reza Mehvar
      Drug Metabolism and Disposition December 2004, 32 (12) 1446-1454; DOI: https://doi.org/10.1124/dmd.104.001487

  10. Mikkola, Jouni

    1. ASSESSMENT OF CATECHOL INDUCTION AND GLUCURONIDATION IN RAT LIVER MICROSOMES
      Eivor Elovaara, Jouni Mikkola, Leena Luukkanen, Laurence Antonio, Sylvie Fournel-Gigleux, Brian Burchell, Jacques Magdalou and Jyrki Taskinen
      Drug Metabolism and Disposition December 2004, 32 (12) 1426-1433; DOI: https://doi.org/10.1124/dmd.104.000992

  11. Milad, Mark A.

    1. EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
      Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
      Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208

  12. Mizobuchi, Minoru

    1. MECHANISM OF THE DRUG INTERACTION BETWEEN VALPROIC ACID AND CARBAPENEM ANTIBIOTICS IN MONKEYS AND RATS
      Yoshitsugu Nakajima, Minoru Mizobuchi, Masahiro Nakamura, Hidetoshi Takagi, Haruhisa Inagaki, Goro Kominami, Masahiro Koike and Toshiro Yamaguchi
      Drug Metabolism and Disposition December 2004, 32 (12) 1383-1391; DOI: https://doi.org/10.1124/dmd.104.000661

  13. Mohri, Kiminori

    1. IDENTIFICATION OF THE RABBIT LIVER UDP-GLUCURONOSYLTRANSFERASE CATALYZING THE GLUCURONIDATION OF 4-ETHOXYPHENYLUREA (DULCIN)
      Yoshihiro Uesawa, Adam G. Staines, Audrey O'Sullivan, Kiminori Mohri and Brian Burchell
      Drug Metabolism and Disposition December 2004, 32 (12) 1476-1481; DOI: https://doi.org/10.1124/dmd.104.001206

N

  1. Nakajima, Miki

    1. EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Miho Kataoka, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2004, 32 (12) 1402-1410; DOI: https://doi.org/10.1124/dmd.104.001347

  2. Nakajima, Yoshitsugu

    1. MECHANISM OF THE DRUG INTERACTION BETWEEN VALPROIC ACID AND CARBAPENEM ANTIBIOTICS IN MONKEYS AND RATS
      Yoshitsugu Nakajima, Minoru Mizobuchi, Masahiro Nakamura, Hidetoshi Takagi, Haruhisa Inagaki, Goro Kominami, Masahiro Koike and Toshiro Yamaguchi
      Drug Metabolism and Disposition December 2004, 32 (12) 1383-1391; DOI: https://doi.org/10.1124/dmd.104.000661

  3. Nakamura, Masahiro

    1. MECHANISM OF THE DRUG INTERACTION BETWEEN VALPROIC ACID AND CARBAPENEM ANTIBIOTICS IN MONKEYS AND RATS
      Yoshitsugu Nakajima, Minoru Mizobuchi, Masahiro Nakamura, Hidetoshi Takagi, Haruhisa Inagaki, Goro Kominami, Masahiro Koike and Toshiro Yamaguchi
      Drug Metabolism and Disposition December 2004, 32 (12) 1383-1391; DOI: https://doi.org/10.1124/dmd.104.000661

  4. Nicoll-Griffith, Deborah A.

    1. USE OF A BENZYLOXY-SUBSTITUTED LACTONE CYCLOOXYGENASE-2 INHIBITOR AS A SELECTIVE FLUORESCENT PROBE FOR CYP3A ACTIVITY IN PRIMARY CULTURED RAT AND HUMAN HEPATOCYTES
      Deborah A. Nicoll-Griffith, Nathalie Chauret, Robert Houle, Stephen H. Day, Michelle D'Antoni and José M. Silva
      Drug Metabolism and Disposition December 2004, 32 (12) 1509-1515; DOI: https://doi.org/10.1124/dmd.32.12.1509

  5. Nitzan, Dov

    1. IDENTIFICATION OF GLUTATHIONE-DERIVED METABOLITES FROM AN IP RECEPTOR ANTAGONIST
      William L. Fitch, Pamela W. Berry, Yaping Tu, Ali Tabatabaei, Lee Lowrie, Francisco Lopez-Tapia, Yanzhou Liu, Dov Nitzan, Mohammad R. Masjedizadeh and Aravamuthan Varadarajan
      Drug Metabolism and Disposition December 2004, 32 (12) 1482-1490; DOI: https://doi.org/10.1124/dmd.104.000471

O

  1. O'Sullivan, Audrey

    1. IDENTIFICATION OF THE RABBIT LIVER UDP-GLUCURONOSYLTRANSFERASE CATALYZING THE GLUCURONIDATION OF 4-ETHOXYPHENYLUREA (DULCIN)
      Yoshihiro Uesawa, Adam G. Staines, Audrey O'Sullivan, Kiminori Mohri and Brian Burchell
      Drug Metabolism and Disposition December 2004, 32 (12) 1476-1481; DOI: https://doi.org/10.1124/dmd.104.001206

  2. Oatis, John E.

    1. HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS
      Thomas Walle, Faye Hsieh, Mark H. DeLegge, John E. Oatis and U. Kristina Walle
      Drug Metabolism and Disposition December 2004, 32 (12) 1377-1382; DOI: https://doi.org/10.1124/dmd.104.000885

  3. Owens, I. S.

    1. RESPONSE TO THE LETTER TO THE EDITOR BY DRS. N. PICARD AND P. MARQUET REGARDING A PUBLICATION: BASU ET AL., DRUG METABOLISM AND DISPOSITION (32:768–773, (2004)
      N. K. Basu, L. Kole, S. Kubota and I. S. Owens
      Drug Metabolism and Disposition December 2004, 32 (12) 1525; DOI: https://doi.org/10.1124/dmd.104.002345

P

  1. Padhi, Desmond

    1. METABOLISM AND DISPOSITION OF CALCIMIMETIC AGENT CINACALCET HCL IN HUMANS AND ANIMAL MODELS
      Gondi N. Kumar, Christopher Sproul, Leszek Poppe, Sharon Turner, Mark Gohdes, Hesham Ghoborah, Desmond Padhi and Lorin Roskos
      Drug Metabolism and Disposition December 2004, 32 (12) 1491-1500; DOI: https://doi.org/10.1124/dmd.104.000604

  2. Pereira, Clifford B.

    1. DIFFERENCES IN FMO2*1 ALLELIC FREQUENCY BETWEEN HISPANICS OF PUERTO RICAN AND MEXICAN DESCENT
      Sharon K. Krueger, Lisbeth K. Siddens, Sarah R. Martin, Zhen Yu, Clifford B. Pereira, Erwin T. Cabacungan, Ronald N. Hines, Kristin G. Ardlie, Judy L. Raucy and David E. Williams
      Drug Metabolism and Disposition December 2004, 32 (12) 1337-1340; DOI: https://doi.org/10.1124/dmd.104.001099

  3. Picard, Nicolas

    1. IN VITRO STUDY OF MYCOPHENOLIC ACID GLUCURONIDATION
      Nicolas Picard and Pierre Marquet
      Drug Metabolism and Disposition December 2004, 32 (12) 1524; DOI: https://doi.org/10.1124/dmd.104.001982

  4. Poppe, Leszek

    1. METABOLISM AND DISPOSITION OF CALCIMIMETIC AGENT CINACALCET HCL IN HUMANS AND ANIMAL MODELS
      Gondi N. Kumar, Christopher Sproul, Leszek Poppe, Sharon Turner, Mark Gohdes, Hesham Ghoborah, Desmond Padhi and Lorin Roskos
      Drug Metabolism and Disposition December 2004, 32 (12) 1491-1500; DOI: https://doi.org/10.1124/dmd.104.000604

Q

  1. Qian, Mingxin

    1. THE CHIMPANZEE (PAN TROGLODYTES) AS A PHARMACOKINETIC MODEL FOR SELECTION OF DRUG CANDIDATES: MODEL CHARACTERIZATION AND APPLICATION
      Harvey Wong, Scott J. Grossman, Stephen A. Bai, Sharon Diamond, Matthew R. Wright, James E. Grace, Mingxin Qian, Kan He, Krishnaswamy Yeleswaram and David D. Christ
      Drug Metabolism and Disposition December 2004, 32 (12) 1359-1369; DOI: https://doi.org/10.1124/dmd.104.000943

R

  1. Raucy, Judy L.

    1. DIFFERENCES IN FMO2*1 ALLELIC FREQUENCY BETWEEN HISPANICS OF PUERTO RICAN AND MEXICAN DESCENT
      Sharon K. Krueger, Lisbeth K. Siddens, Sarah R. Martin, Zhen Yu, Clifford B. Pereira, Erwin T. Cabacungan, Ronald N. Hines, Kristin G. Ardlie, Judy L. Raucy and David E. Williams
      Drug Metabolism and Disposition December 2004, 32 (12) 1337-1340; DOI: https://doi.org/10.1124/dmd.104.001099
    2. CONVERSION OF THE HIV PROTEASE INHIBITOR NELFINAVIR TO A BIOACTIVE METABOLITE BY HUMAN LIVER CYP2C19
      Vandana N. Hirani, Judy L. Raucy and Jerome M. Lasker
      Drug Metabolism and Disposition December 2004, 32 (12) 1462-1467; DOI: https://doi.org/10.1124/dmd.104.001743

  2. Rose, Kelly A.

    1. EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
      Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
      Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208

  3. Roskos, Lorin

    1. METABOLISM AND DISPOSITION OF CALCIMIMETIC AGENT CINACALCET HCL IN HUMANS AND ANIMAL MODELS
      Gondi N. Kumar, Christopher Sproul, Leszek Poppe, Sharon Turner, Mark Gohdes, Hesham Ghoborah, Desmond Padhi and Lorin Roskos
      Drug Metabolism and Disposition December 2004, 32 (12) 1491-1500; DOI: https://doi.org/10.1124/dmd.104.000604

  4. Rostami-Hodjegan, Amin

    1. PREDICTING THE CLEARANCE OF CYP2C9 SUBSTRATES
      Karen Rowland Yeo, Eleanor M. Howgate, Geoffrey T. Tucker and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition December 2004, 32 (12) 1522; DOI: https://doi.org/10.1124/dmd.104.001792

S

  1. Sadagopan, Nalini

    1. EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
      Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
      Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208

  2. Sahi, Jasminder

    1. EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
      Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
      Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208

  3. Sato, Hitoshi

    1. IN VITRO AND IN VIVO CORRELATION OF THE INHIBITORY EFFECT OF CYCLOSPORIN A ON THE TRANSPORTER-MEDIATED HEPATIC UPTAKE OF CERIVASTATIN IN RATS
      Yoshihisa Shitara, Masaru Hirano, Yasuhisa Adachi, Tomoo Itoh, Hitoshi Sato and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2004, 32 (12) 1468-1475; DOI: https://doi.org/10.1124/dmd.32.12.1468

  4. Sausville, Edward A.

    1. FLUORINATED 2-(4-AMINO-3-METHYLPHENYL)BENZOTHIAZOLES INDUCE CYP1A1 EXPRESSION, BECOME METABOLIZED, AND BIND TO MACROMOLECULES IN SENSITIVE HUMAN CANCER CELLS
      Eileen Brantley, Valentina Trapani, Michael C. Alley, Curtis D. Hose, Tracey D. Bradshaw, Malcolm F. G. Stevens, Edward A. Sausville and Sherman F. Stinson
      Drug Metabolism and Disposition December 2004, 32 (12) 1392-1401; DOI: https://doi.org/10.1124/dmd.104.001057

  5. Shen, Jian

    1. IDENTIFICATION OF CRITICAL AMINO ACID RESIDUES OF HUMAN CYP2A13 FOR THE METABOLIC ACTIVATION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE, A TOBACCO-SPECIFIC CARCINOGEN
      Xiao-Yang He, Jian Shen, Xinxin Ding, Anthony Y. H. Lu and Jun-Yan Hong
      Drug Metabolism and Disposition December 2004, 32 (12) 1516-1521; DOI: https://doi.org/10.1124/dmd.104.001370

  6. Shin, Sang-Goo

    1. HAPLOTYPE STRUCTURE AND ALLELE FREQUENCIES OF CYP2B6 IN A KOREAN POPULATION
      Joo-Youn Cho, Hyeong-Seok Lim, Jae-Yong Chung, Kyung-Sang Yu, Jung-Ryul Kim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition December 2004, 32 (12) 1341-1344; DOI: https://doi.org/10.1124/dmd.104.001107

  7. Shitara, Yoshihisa

    1. IN VITRO AND IN VIVO CORRELATION OF THE INHIBITORY EFFECT OF CYCLOSPORIN A ON THE TRANSPORTER-MEDIATED HEPATIC UPTAKE OF CERIVASTATIN IN RATS
      Yoshihisa Shitara, Masaru Hirano, Yasuhisa Adachi, Tomoo Itoh, Hitoshi Sato and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2004, 32 (12) 1468-1475; DOI: https://doi.org/10.1124/dmd.32.12.1468

  8. Siddens, Lisbeth K.

    1. DIFFERENCES IN FMO2*1 ALLELIC FREQUENCY BETWEEN HISPANICS OF PUERTO RICAN AND MEXICAN DESCENT
      Sharon K. Krueger, Lisbeth K. Siddens, Sarah R. Martin, Zhen Yu, Clifford B. Pereira, Erwin T. Cabacungan, Ronald N. Hines, Kristin G. Ardlie, Judy L. Raucy and David E. Williams
      Drug Metabolism and Disposition December 2004, 32 (12) 1337-1340; DOI: https://doi.org/10.1124/dmd.104.001099

  9. Silva, José M.

    1. USE OF A BENZYLOXY-SUBSTITUTED LACTONE CYCLOOXYGENASE-2 INHIBITOR AS A SELECTIVE FLUORESCENT PROBE FOR CYP3A ACTIVITY IN PRIMARY CULTURED RAT AND HUMAN HEPATOCYTES
      Deborah A. Nicoll-Griffith, Nathalie Chauret, Robert Houle, Stephen H. Day, Michelle D'Antoni and José M. Silva
      Drug Metabolism and Disposition December 2004, 32 (12) 1509-1515; DOI: https://doi.org/10.1124/dmd.32.12.1509

  10. SjÖberg, Helena

    1. RESPONSE: PREDICTING THE CLEARANCE OF CYP2C9 SUBSTRATES
      Tommy B. Andersson, Eva Bredberg, Hans Ericsson and Helena SjÖberg
      Drug Metabolism and Disposition December 2004, 32 (12) 1523; DOI: https://doi.org/10.1124/dmd.104.002329

  11. Soeno, Yoshinori

    1. EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Miho Kataoka, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2004, 32 (12) 1402-1410; DOI: https://doi.org/10.1124/dmd.104.001347

  12. Sproul, Christopher

    1. METABOLISM AND DISPOSITION OF CALCIMIMETIC AGENT CINACALCET HCL IN HUMANS AND ANIMAL MODELS
      Gondi N. Kumar, Christopher Sproul, Leszek Poppe, Sharon Turner, Mark Gohdes, Hesham Ghoborah, Desmond Padhi and Lorin Roskos
      Drug Metabolism and Disposition December 2004, 32 (12) 1491-1500; DOI: https://doi.org/10.1124/dmd.104.000604

  13. Staines, Adam G.

    1. IDENTIFICATION OF THE RABBIT LIVER UDP-GLUCURONOSYLTRANSFERASE CATALYZING THE GLUCURONIDATION OF 4-ETHOXYPHENYLUREA (DULCIN)
      Yoshihiro Uesawa, Adam G. Staines, Audrey O'Sullivan, Kiminori Mohri and Brian Burchell
      Drug Metabolism and Disposition December 2004, 32 (12) 1476-1481; DOI: https://doi.org/10.1124/dmd.104.001206

  14. Stern, Ralph H.

    1. EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
      Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
      Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208

  15. Stevens, Malcolm F. G.

    1. FLUORINATED 2-(4-AMINO-3-METHYLPHENYL)BENZOTHIAZOLES INDUCE CYP1A1 EXPRESSION, BECOME METABOLIZED, AND BIND TO MACROMOLECULES IN SENSITIVE HUMAN CANCER CELLS
      Eileen Brantley, Valentina Trapani, Michael C. Alley, Curtis D. Hose, Tracey D. Bradshaw, Malcolm F. G. Stevens, Edward A. Sausville and Sherman F. Stinson
      Drug Metabolism and Disposition December 2004, 32 (12) 1392-1401; DOI: https://doi.org/10.1124/dmd.104.001057

  16. Stilgenbauer, Linda

    1. EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
      Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
      Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208

  17. Stinson, Sherman F.

    1. FLUORINATED 2-(4-AMINO-3-METHYLPHENYL)BENZOTHIAZOLES INDUCE CYP1A1 EXPRESSION, BECOME METABOLIZED, AND BIND TO MACROMOLECULES IN SENSITIVE HUMAN CANCER CELLS
      Eileen Brantley, Valentina Trapani, Michael C. Alley, Curtis D. Hose, Tracey D. Bradshaw, Malcolm F. G. Stevens, Edward A. Sausville and Sherman F. Stinson
      Drug Metabolism and Disposition December 2004, 32 (12) 1392-1401; DOI: https://doi.org/10.1124/dmd.104.001057

  18. Sugiyama, Yuichi

    1. IN VITRO AND IN VIVO CORRELATION OF THE INHIBITORY EFFECT OF CYCLOSPORIN A ON THE TRANSPORTER-MEDIATED HEPATIC UPTAKE OF CERIVASTATIN IN RATS
      Yoshihisa Shitara, Masaru Hirano, Yasuhisa Adachi, Tomoo Itoh, Hitoshi Sato and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2004, 32 (12) 1468-1475; DOI: https://doi.org/10.1124/dmd.32.12.1468

T

  1. Tabatabaei, Ali

    1. IDENTIFICATION OF GLUTATHIONE-DERIVED METABOLITES FROM AN IP RECEPTOR ANTAGONIST
      William L. Fitch, Pamela W. Berry, Yaping Tu, Ali Tabatabaei, Lee Lowrie, Francisco Lopez-Tapia, Yanzhou Liu, Dov Nitzan, Mohammad R. Masjedizadeh and Aravamuthan Varadarajan
      Drug Metabolism and Disposition December 2004, 32 (12) 1482-1490; DOI: https://doi.org/10.1124/dmd.104.000471

  2. Takagi, Hidetoshi

    1. MECHANISM OF THE DRUG INTERACTION BETWEEN VALPROIC ACID AND CARBAPENEM ANTIBIOTICS IN MONKEYS AND RATS
      Yoshitsugu Nakajima, Minoru Mizobuchi, Masahiro Nakamura, Hidetoshi Takagi, Haruhisa Inagaki, Goro Kominami, Masahiro Koike and Toshiro Yamaguchi
      Drug Metabolism and Disposition December 2004, 32 (12) 1383-1391; DOI: https://doi.org/10.1124/dmd.104.000661

  3. Taskinen, Jyrki

    1. ASSESSMENT OF CATECHOL INDUCTION AND GLUCURONIDATION IN RAT LIVER MICROSOMES
      Eivor Elovaara, Jouni Mikkola, Leena Luukkanen, Laurence Antonio, Sylvie Fournel-Gigleux, Brian Burchell, Jacques Magdalou and Jyrki Taskinen
      Drug Metabolism and Disposition December 2004, 32 (12) 1426-1433; DOI: https://doi.org/10.1124/dmd.104.000992

  4. Tateno, Chise

    1. EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Miho Kataoka, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2004, 32 (12) 1402-1410; DOI: https://doi.org/10.1124/dmd.104.001347

  5. Tezuka, Yasuhiro

    1. IDENTIFICATION AND CHARACTERIZATION OF POTENT CYP3A4 INHIBITORS IN SCHISANDRA FRUIT EXTRACT
      Hiroshi Iwata, Yasuhiro Tezuka, Shigetoshi Kadota, Akira Hiratsuka and Tadashi Watabe
      Drug Metabolism and Disposition December 2004, 32 (12) 1351-1358; DOI: https://doi.org/10.1124/dmd.104.000646

  6. Thummel, Kenneth E.

    1. EVIDENCE OF SIGNIFICANT CONTRIBUTION FROM CYP3A5 TO HEPATIC DRUG METABOLISM
      Weili Huang, Yvonne S. Lin, Donavon J. McConn, Justina C. Calamia, Rheem A. Totah, Nina Isoherranen, Mary Glodowski and Kenneth E. Thummel
      Drug Metabolism and Disposition December 2004, 32 (12) 1434-1445; DOI: https://doi.org/10.1124/dmd.104.001313

  7. Totah, Rheem A.

    1. EVIDENCE OF SIGNIFICANT CONTRIBUTION FROM CYP3A5 TO HEPATIC DRUG METABOLISM
      Weili Huang, Yvonne S. Lin, Donavon J. McConn, Justina C. Calamia, Rheem A. Totah, Nina Isoherranen, Mary Glodowski and Kenneth E. Thummel
      Drug Metabolism and Disposition December 2004, 32 (12) 1434-1445; DOI: https://doi.org/10.1124/dmd.104.001313

  8. Trapani, Valentina

    1. FLUORINATED 2-(4-AMINO-3-METHYLPHENYL)BENZOTHIAZOLES INDUCE CYP1A1 EXPRESSION, BECOME METABOLIZED, AND BIND TO MACROMOLECULES IN SENSITIVE HUMAN CANCER CELLS
      Eileen Brantley, Valentina Trapani, Michael C. Alley, Curtis D. Hose, Tracey D. Bradshaw, Malcolm F. G. Stevens, Edward A. Sausville and Sherman F. Stinson
      Drug Metabolism and Disposition December 2004, 32 (12) 1392-1401; DOI: https://doi.org/10.1124/dmd.104.001057

  9. Tu, Yaping

    1. IDENTIFICATION OF GLUTATHIONE-DERIVED METABOLITES FROM AN IP RECEPTOR ANTAGONIST
      William L. Fitch, Pamela W. Berry, Yaping Tu, Ali Tabatabaei, Lee Lowrie, Francisco Lopez-Tapia, Yanzhou Liu, Dov Nitzan, Mohammad R. Masjedizadeh and Aravamuthan Varadarajan
      Drug Metabolism and Disposition December 2004, 32 (12) 1482-1490; DOI: https://doi.org/10.1124/dmd.104.000471

  10. Tucker, Geoffrey T.

    1. PREDICTING THE CLEARANCE OF CYP2C9 SUBSTRATES
      Karen Rowland Yeo, Eleanor M. Howgate, Geoffrey T. Tucker and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition December 2004, 32 (12) 1522; DOI: https://doi.org/10.1124/dmd.104.001792

  11. Turner, Sharon

    1. METABOLISM AND DISPOSITION OF CALCIMIMETIC AGENT CINACALCET HCL IN HUMANS AND ANIMAL MODELS
      Gondi N. Kumar, Christopher Sproul, Leszek Poppe, Sharon Turner, Mark Gohdes, Hesham Ghoborah, Desmond Padhi and Lorin Roskos
      Drug Metabolism and Disposition December 2004, 32 (12) 1491-1500; DOI: https://doi.org/10.1124/dmd.104.000604

U

  1. Uesawa, Yoshihiro

    1. IDENTIFICATION OF THE RABBIT LIVER UDP-GLUCURONOSYLTRANSFERASE CATALYZING THE GLUCURONIDATION OF 4-ETHOXYPHENYLUREA (DULCIN)
      Yoshihiro Uesawa, Adam G. Staines, Audrey O'Sullivan, Kiminori Mohri and Brian Burchell
      Drug Metabolism and Disposition December 2004, 32 (12) 1476-1481; DOI: https://doi.org/10.1124/dmd.104.001206

V

  1. Vanrenterghem, Yves

    1. THE RATE OF GASTRIC EMPTYING DETERMINES THE TIMING BUT NOT THE EXTENT OF ORAL TACROLIMUS ABSORPTION: SIMULTANEOUS MEASUREMENT OF DRUG EXPOSURE AND GASTRIC EMPTYING BY CARBON-14-OCTANOIC ACID BREATH TEST IN STABLE RENAL ALLOGRAFT RECIPIENTS
      Dirk R. J. Kuypers, Kathleen Claes, P. Evenepoel, B. Maes and Yves Vanrenterghem
      Drug Metabolism and Disposition December 2004, 32 (12) 1421-1425; DOI: https://doi.org/10.1124/dmd.104.001503

  2. Varadarajan, Aravamuthan

    1. IDENTIFICATION OF GLUTATHIONE-DERIVED METABOLITES FROM AN IP RECEPTOR ANTAGONIST
      William L. Fitch, Pamela W. Berry, Yaping Tu, Ali Tabatabaei, Lee Lowrie, Francisco Lopez-Tapia, Yanzhou Liu, Dov Nitzan, Mohammad R. Masjedizadeh and Aravamuthan Varadarajan
      Drug Metabolism and Disposition December 2004, 32 (12) 1482-1490; DOI: https://doi.org/10.1124/dmd.104.000471

  3. Vuppugalla, Ragini

    1. SHORT-TERM INHIBITORY EFFECTS OF NITRIC OXIDE ON CYTOCHROME P450-MEDIATED DRUG METABOLISM: TIME DEPENDENCY AND REVERSIBILITY PROFILES IN ISOLATED PERFUSED RAT LIVERS
      Ragini Vuppugalla and Reza Mehvar
      Drug Metabolism and Disposition December 2004, 32 (12) 1446-1454; DOI: https://doi.org/10.1124/dmd.104.001487

W

  1. Walle, Thomas

    1. HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS
      Thomas Walle, Faye Hsieh, Mark H. DeLegge, John E. Oatis and U. Kristina Walle
      Drug Metabolism and Disposition December 2004, 32 (12) 1377-1382; DOI: https://doi.org/10.1124/dmd.104.000885

  2. Walle, U. Kristina

    1. HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS
      Thomas Walle, Faye Hsieh, Mark H. DeLegge, John E. Oatis and U. Kristina Walle
      Drug Metabolism and Disposition December 2004, 32 (12) 1377-1382; DOI: https://doi.org/10.1124/dmd.104.000885

  3. Wang, Jun-Sheng

    1. MULTIPLE NIGHT-TIME DOSES OF VALERIAN (Valeriana officinalis) HAD MINIMAL EFFECTS ON CYP3A4 ACTIVITY AND NO EFFECT ON CYP2D6 ACTIVITY IN HEALTHY VOLUNTEERS
      Jennifer L. Donovan, C. Lindsay DeVane, Kenneth D. Chavin, Jun-Sheng Wang, Bryan B. Gibson, Holly A. Gefroh and John S. Markowitz
      Drug Metabolism and Disposition December 2004, 32 (12) 1333-1336; DOI: https://doi.org/10.1124/dmd.104.001164

  4. Watabe, Tadashi

    1. IDENTIFICATION AND CHARACTERIZATION OF POTENT CYP3A4 INHIBITORS IN SCHISANDRA FRUIT EXTRACT
      Hiroshi Iwata, Yasuhiro Tezuka, Shigetoshi Kadota, Akira Hiratsuka and Tadashi Watabe
      Drug Metabolism and Disposition December 2004, 32 (12) 1351-1358; DOI: https://doi.org/10.1124/dmd.104.000646

  5. Williams, David E.

    1. DIFFERENCES IN FMO2*1 ALLELIC FREQUENCY BETWEEN HISPANICS OF PUERTO RICAN AND MEXICAN DESCENT
      Sharon K. Krueger, Lisbeth K. Siddens, Sarah R. Martin, Zhen Yu, Clifford B. Pereira, Erwin T. Cabacungan, Ronald N. Hines, Kristin G. Ardlie, Judy L. Raucy and David E. Williams
      Drug Metabolism and Disposition December 2004, 32 (12) 1337-1340; DOI: https://doi.org/10.1124/dmd.104.001099

  6. Wong, Harvey

    1. THE CHIMPANZEE (PAN TROGLODYTES) AS A PHARMACOKINETIC MODEL FOR SELECTION OF DRUG CANDIDATES: MODEL CHARACTERIZATION AND APPLICATION
      Harvey Wong, Scott J. Grossman, Stephen A. Bai, Sharon Diamond, Matthew R. Wright, James E. Grace, Mingxin Qian, Kan He, Krishnaswamy Yeleswaram and David D. Christ
      Drug Metabolism and Disposition December 2004, 32 (12) 1359-1369; DOI: https://doi.org/10.1124/dmd.104.000943

  7. Wright, Matthew R.

    1. THE CHIMPANZEE (PAN TROGLODYTES) AS A PHARMACOKINETIC MODEL FOR SELECTION OF DRUG CANDIDATES: MODEL CHARACTERIZATION AND APPLICATION
      Harvey Wong, Scott J. Grossman, Stephen A. Bai, Sharon Diamond, Matthew R. Wright, James E. Grace, Mingxin Qian, Kan He, Krishnaswamy Yeleswaram and David D. Christ
      Drug Metabolism and Disposition December 2004, 32 (12) 1359-1369; DOI: https://doi.org/10.1124/dmd.104.000943

Y

  1. Yamaguchi, Toshiro

    1. MECHANISM OF THE DRUG INTERACTION BETWEEN VALPROIC ACID AND CARBAPENEM ANTIBIOTICS IN MONKEYS AND RATS
      Yoshitsugu Nakajima, Minoru Mizobuchi, Masahiro Nakamura, Hidetoshi Takagi, Haruhisa Inagaki, Goro Kominami, Masahiro Koike and Toshiro Yamaguchi
      Drug Metabolism and Disposition December 2004, 32 (12) 1383-1391; DOI: https://doi.org/10.1124/dmd.104.000661

  2. Yeleswaram, Krishnaswamy

    1. THE CHIMPANZEE (PAN TROGLODYTES) AS A PHARMACOKINETIC MODEL FOR SELECTION OF DRUG CANDIDATES: MODEL CHARACTERIZATION AND APPLICATION
      Harvey Wong, Scott J. Grossman, Stephen A. Bai, Sharon Diamond, Matthew R. Wright, James E. Grace, Mingxin Qian, Kan He, Krishnaswamy Yeleswaram and David D. Christ
      Drug Metabolism and Disposition December 2004, 32 (12) 1359-1369; DOI: https://doi.org/10.1124/dmd.104.000943

  3. Yeo, Karen Rowland

    1. PREDICTING THE CLEARANCE OF CYP2C9 SUBSTRATES
      Karen Rowland Yeo, Eleanor M. Howgate, Geoffrey T. Tucker and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition December 2004, 32 (12) 1522; DOI: https://doi.org/10.1124/dmd.104.001792

  4. Yokoi, Tsuyoshi

    1. EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Miho Kataoka, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2004, 32 (12) 1402-1410; DOI: https://doi.org/10.1124/dmd.104.001347

  5. Yoshizato, Katsutoshi

    1. EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Miho Kataoka, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2004, 32 (12) 1402-1410; DOI: https://doi.org/10.1124/dmd.104.001347

  6. Yu, Kyung-Sang

    1. HAPLOTYPE STRUCTURE AND ALLELE FREQUENCIES OF CYP2B6 IN A KOREAN POPULATION
      Joo-Youn Cho, Hyeong-Seok Lim, Jae-Yong Chung, Kyung-Sang Yu, Jung-Ryul Kim, Sang-Goo Shin and In-Jin Jang
      Drug Metabolism and Disposition December 2004, 32 (12) 1341-1344; DOI: https://doi.org/10.1124/dmd.104.001107

  7. Yu, Zhen

    1. DIFFERENCES IN FMO2*1 ALLELIC FREQUENCY BETWEEN HISPANICS OF PUERTO RICAN AND MEXICAN DESCENT
      Sharon K. Krueger, Lisbeth K. Siddens, Sarah R. Martin, Zhen Yu, Clifford B. Pereira, Erwin T. Cabacungan, Ronald N. Hines, Kristin G. Ardlie, Judy L. Raucy and David E. Williams
      Drug Metabolism and Disposition December 2004, 32 (12) 1337-1340; DOI: https://doi.org/10.1124/dmd.104.001099

Z

  1. Zheng, Jiang

    1. DETECTION OF GLUTATHIONE CONJUGATES DERIVED FROM 4-IPOMEANOL METABOLISM IN BILE OF RATS BY LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY
      Teresa M. Alvarez-Diez and Jiang Zheng
      Drug Metabolism and Disposition December 2004, 32 (12) 1345-1350; DOI: https://doi.org/10.1124/dmd.104.000406

  2. Zheng, Xianxian

    1. EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
      Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
      Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208
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