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Research ArticleArticle

EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO

Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
Drug Metabolism and Disposition December 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208

Article Information

vol. 32 no. 12 1370-1376
DOI 
https://doi.org/10.1124/dmd.104.000208
PubMed 
15333513
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 16, 2004
  • Accepted August 24, 2004
  • Published online November 18, 2004.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jasminder Sahi,
  2. Ralph H. Stern,
  3. Mark A. Milad,
  4. Kelly A. Rose,
  5. Gordon Gibson,
  6. Xianxian Zheng,
  7. Linda Stilgenbauer,
  8. Nalini Sadagopan,
  9. Summer Jolley,
  10. Darryl Gilbert and
  11. Edward L. LeCluyse
  1. Departments of Pharmacokinetics, Dynamics and Metabolism (J.S., K.A.R., L.S., N.S.), Experimental Medicine (R.H.S.), Clinical Pharmacokinetics and Pharmacodynamics (M.A.M.), and Molecular Biology (X.Z.), Pfizer Global Research and Development, Ann Arbor, Michigan; Clinical Studies Centers, LLC, Little Rock, Arkansas (G.G.); and Division of Drug Delivery and Disposition, School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina (S.J., D.G., E.L.L.)
  1. Address correspondence to:
    Dr. Jasminder Sahi, Pfizer Global Research and Development, 2800 Plymouth Road, Ann Arbor MI 48105. E-mail: Jasminder.Sahi{at}Pfizer.com
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Research ArticleArticle

EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO

Jasminder Sahi, Ralph H. Stern, Mark A. Milad, Kelly A. Rose, Gordon Gibson, Xianxian Zheng, Linda Stilgenbauer, Nalini Sadagopan, Summer Jolley, Darryl Gilbert and Edward L. LeCluyse
Drug Metabolism and Disposition December 1, 2004, 32 (12) 1370-1376; DOI: https://doi.org/10.1124/dmd.104.000208
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