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Research ArticleArticle

DIFFERENTIAL ENANTIOSELECTIVITY AND PRODUCT-DEPENDENT ACTIVATION AND INHIBITION IN METABOLISM OF VERAPAMIL BY HUMAN CYP3AS

Lixin Shen, John F. Fitzloff and Chyung S. Cook
Drug Metabolism and Disposition February 2004, 32 (2) 186-196; DOI: https://doi.org/10.1124/dmd.32.2.186

Article Information

vol. 32 no. 2 186-196
DOI 
https://doi.org/10.1124/dmd.32.2.186
PubMed 
14744940
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received July 24, 2003
  • Accepted September 30, 2003
  • Published online January 26, 2004.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Lixin Shen,
  2. John F. Fitzloff and
  3. Chyung S. Cook
  1. Pharmacokinetics, Dynamics and Metabolism, Pfizer, Skokie, Illinois (L.S., C.S.C.); and Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois (L.S., J.F.F., C.S.C.)
  1. Address correspondence to:
    Dr. Chyung S. Cook, Baxter Healthcare Corporation, WG2-1S, Route 120 and Wilson Road, Round Lake, IL 60073. E-mail: chyung_cook{at}baxter.com
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Research ArticleArticle

DIFFERENTIAL ENANTIOSELECTIVITY AND PRODUCT-DEPENDENT ACTIVATION AND INHIBITION IN METABOLISM OF VERAPAMIL BY HUMAN CYP3AS

Lixin Shen, John F. Fitzloff and Chyung S. Cook
Drug Metabolism and Disposition February 1, 2004, 32 (2) 186-196; DOI: https://doi.org/10.1124/dmd.32.2.186
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