Table of Contents

Articles

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  RENAL TRANSPORT OF ORGANIC COMPOUNDS MEDIATED BY MOUSE ORGANIC ANION TRANSPORTER 3 (MOAT3): FURTHER SUBSTRATE SPECIFICITY OF MOAT3

  Yasuna Kobayashi, Naomi Ohshiro, Ayumi Tsuchiya, Noriko Kohyama, Masayuki Ohbayashi and Toshinori Yamamoto

  Drug Metabolism and Disposition May 2004, 32 (5) 479-483; DOI: https://doi.org/10.1124/dmd.32.5.479
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  THE IMPACT OF CYP2C9 GENETICS AND ORAL CONTRACEPTIVES ON CYTOCHROME P450 2C9 PHENOTYPE

  Mia Sandberg, Inger Johansson, Magnus Christensen, Anders Rane and Erik Eliasson

  Drug Metabolism and Disposition May 2004, 32 (5) 484-489; DOI: https://doi.org/10.1124/dmd.32.5.484
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  IN VITRO METABOLISM OF THE PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR, WORTMANNIN, BY CARBONYL REDUCTASE

  Julianne L. Holleran, Julien Fourcade, Merrill J. Egorin, Julie L. Eiseman, Robert A. Parise, Steven M. Musser, Kevin D. White, Joseph M. Covey, Gerald L. Forrest and Su-Shu Pan

  Drug Metabolism and Disposition May 2004, 32 (5) 490-496; DOI: https://doi.org/10.1124/dmd.32.5.490
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  STRONG INHIBITORY EFFECTS OF COMMON TEA CATECHINS AND BIOFLAVONOIDS ON THE O-METHYLATION OF CATECHOL ESTROGENS CATALYZED BY HUMAN LIVER CYTOSOLIC CATECHOL-O-METHYLTRANSFERASE

  Mime Nagai, Allan H. Conney and Bao Ting Zhu

  Drug Metabolism and Disposition May 2004, 32 (5) 497-504; DOI: https://doi.org/10.1124/dmd.32.5.497
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  HYDROLYSIS OF IRINOTECAN AND ITS OXIDATIVE METABOLITES, 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO] CARBONYLOXYCAMPTOTHECIN AND 7-ETHYL-10-[4-(1-PIPERIDINO)-1-AMINO]-CARBONYLOXYCAMPTOTHECIN, BY HUMAN CARBOXYLESTERASES CES1A1, CES2, AND A NEWLY EXPRESSED CARBOXYLESTERASE ISOENZYME, CES3

  Sonal P. Sanghani, Sara K. Quinney, Tyler B. Fredenburg, Wilhelmina I. Davis, Daryl J. Murry and William F. Bosron

  Drug Metabolism and Disposition May 2004, 32 (5) 505-511; DOI: https://doi.org/10.1124/dmd.32.5.505
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  INDUCTION AND INHIBITION OF CYTOCHROMES P450 BY THE ST. JOHN'S WORT CONSTITUENT HYPERFORIN IN HUMAN HEPATOCYTE CULTURES

  Bernard J. Komoroski, Shimin Zhang, Hongbo Cai, J. Matthew Hutzler, Reginald Frye, Timothy S. Tracy, Stephen C. Strom, Thomas Lehmann, Catharina Y. W. Ang, Yan Yan Cui and Raman Venkataramanan

  Drug Metabolism and Disposition May 2004, 32 (5) 512-518; DOI: https://doi.org/10.1124/dmd.32.5.512
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  INFLUX AND EFFLUX TRANSPORT OF H1-ANTAGONIST EPINASTINE ACROSS THE BLOOD-BRAIN BARRIER

  Naoki Ishiguro, Takashi Nozawa, Akiko Tsujihata, Asami Saito, Wataru Kishimoto, Kazutoshi Yokoyama, Takafumi Yotsumoto, Kenji Sakai, Takashi Igarashi and Ikumi Tamai

  Drug Metabolism and Disposition May 2004, 32 (5) 519-524; DOI: https://doi.org/10.1124/dmd.32.5.519
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  ROLE OF Sp1, C/EBPα, HNF3, AND PXR IN THE BASAL- AND XENOBIOTIC-MEDIATED REGULATION OF THE CYP3A4 GENE

  Vincent Bombail, Kevin Taylor, G. Gordon Gibson and Nick Plant

  Drug Metabolism and Disposition May 2004, 32 (5) 525-535; DOI: https://doi.org/10.1124/dmd.32.5.525
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  COMPARATIVE HEPATIC AND EXTRAHEPATIC ENANTIOSELECTIVE SULFOXIDATION OF ALBENDAZOLE AND FENBENDAZOLE IN SHEEP AND CATTLE

  G. Virkel, A. Lifschitz, J. Sallovitz, A. Pis and C. Lanusse

  Drug Metabolism and Disposition May 2004, 32 (5) 536-544; DOI: https://doi.org/10.1124/dmd.32.5.536
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  AMIDE N-GLUCURONIDATION OF MAXIPOST CATALYZED BY UDP-GLUCURONOSYLTRANSFERASE 2B7 IN HUMANS

  Donglu Zhang, Weiping Zhao, Vikram A. Roongta, James G. Mitroka, Lewis J. Klunk and Mingshe Zhu

  Drug Metabolism and Disposition May 2004, 32 (5) 545-551; DOI: https://doi.org/10.1124/dmd.32.5.545
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  COMPARISON OF FRESH AND CRYOPRESERVED RAT HEPATOCYTE SUSPENSIONS FOR THE PREDICTION OF IN VITRO INTRINSIC CLEARANCE

  Sarah J. Griffin and J. Brian Houston

  Drug Metabolism and Disposition May 2004, 32 (5) 552-558; DOI: https://doi.org/10.1124/dmd.32.5.552
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  INFLUENCE OF PHENYLALANINES 77 AND 138 ON THE STEREOSPECIFICITY OF ARYL SULFOTRANSFERASE IV

  Jonathan J. Sheng, Atmaja Saxena and Michael W. Duffel

  Drug Metabolism and Disposition May 2004, 32 (5) 559-565; DOI: https://doi.org/10.1124/dmd.32.5.559
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  PHARMACOKINETICS AND METABOLISM OF LUMIRACOXIB IN HEALTHY MALE SUBJECTS

  James B. Mangold, Helen Gu, Lolita C. Rodriguez, Johanne Bonner, Janet Dickson and Christiane Rordorf

  Drug Metabolism and Disposition May 2004, 32 (5) 566-571; DOI: https://doi.org/10.1124/dmd.32.5.566
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  QUANTITATIVE PREDICTION OF THE IN VIVO INHIBITION OF DIAZEPAM METABOLISM BY OMEPRAZOLE USING RAT LIVER MICROSOMES AND HEPATOCYTES

  Hannah M. Jones, David Hallifax and J. Brian Houston

  Drug Metabolism and Disposition May 2004, 32 (5) 572-580; DOI: https://doi.org/10.1124/dmd.32.5.572