INTERACTION OF TRIAZOLAM AND KETOCONAZOLE IN P-GLYCOPROTEIN-DEFICIENT MICE

Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine; and Division of Clinical Pharmacology, Tufts-New England Medical Center, Boston, Massachusetts.

Address correspondence to:
Dr. Lisa L. von Moltke, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, 136 Harrison Avenue, Boston MA 02111. E-mail: lisa.vonmoltke{at}tufts.edu

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	Abstract	Full	Pdf
Jul 2004	94	70	98
Aug 2004	65	124	80
Sep 2004	47	129	35
Oct 2004	37	54	30
Nov 2004	29	39	29
Dec 2004	27	50	7
Jan 2005	28	60	15
Feb 2005	15	39	8
Mar 2005	24	57	14
Apr 2005	20	30	5
May 2005	20	50	23
Jun 2005	31	39	11
Jul 2005	12	32	12
Aug 2005	2	24	30
Sep 2005	3	28	12
Oct 2005	7	30	14
Nov 2005	9	26	15
Dec 2005	5	26	9
Jan 2006	6	33	14
Feb 2006	4	36	11
Mar 2006	9	31	18
Apr 2006	1	31	12
May 2006	4	15	7
Jun 2006	2	26	11
Jul 2006	6	13	7
Aug 2006	3	10	7
Sep 2006	4	18	19
Oct 2006	2	25	12
Nov 2006	2	16	11
Dec 2006	3	17	11
Jan 2007	3	13	14
Feb 2007	2	6	7
Mar 2007	5	15	19
Apr 2007	7	19	15
May 2007	11	14	20
Jun 2007	5	15	12
Jul 2007	4	19	15
Aug 2007	4	13	10
Sep 2007	8	11	9
Oct 2007	12	27	17
Nov 2007	5	25	14
Dec 2007	1	8	6
Jan 2008	1	15	11
Feb 2008	2	20	11
Mar 2008	9	11	6
Apr 2008	7	13	13
May 2008	11	21	10
Jun 2008	6	33	20
Jul 2008	13	20	13
Aug 2008	14	26	13
Sep 2008	59	26	22
Oct 2008	17	18	4
Nov 2008	5	13	6
Dec 2008	6	8	9
Jan 2009	8	13	6
Feb 2009	10	12	4
Mar 2009	22	24	7
Apr 2009	9	29	14
May 2009	6	24	6
Jun 2009	4	11	5
Jul 2009	12	21	7
Aug 2009	6	15	9
Sep 2009	13	26	9
Oct 2009	13	23	4
Nov 2009	10	8	8
Dec 2009	14	14	8
Jan 2010	27	11	8
Feb 2010	22	17	12
Mar 2010	20	16	4
Apr 2010	9	17	10
May 2010	14	16	12
Jun 2010	20	14	11
Jul 2010	13	17	5
Aug 2010	7	26	18
Sep 2010	6	13	6
Oct 2010	18	12	5
Nov 2010	9	12	10
Dec 2010	8	9	9
Jan 2011	5	27	13
Feb 2011	17	14	4
Mar 2011	17	16	12
Apr 2011	4	8	5
May 2011	18	30	18
Jun 2011	10	16	17
Jul 2011	23	14	10
Aug 2011	30	19	11
Sep 2011	22	22	16
Oct 2011	37	18	23
Nov 2011	29	17	23
Dec 2011	17	14	13
Jan 2012	24	20	18
Feb 2012	14	18	12
Mar 2012	40	21	6
Apr 2012	28	12	8
May 2012	25	27	17
Jun 2012	27	21	16
Jul 2012	24	23	25
Aug 2012	21	26	13
Sep 2012	33	23	19
Oct 2012	32	36	26
Nov 2012	16	14	20
Dec 2012	27	21	14
Jan 2013	50	38	18
Feb 2013	34	18	20
Mar 2013	18	24	17
Apr 2013	26	27	28
May 2013	44	37	26
Jun 2013	17	13	8
Jul 2013	15	17	11
Aug 2013	18	20	10
Sep 2013	32	8	5
Oct 2013	28	16	7
Nov 2013	26	21	4
Dec 2013	11	10	5
Jan 2014	27	12	3
Feb 2014	10	9	4
Mar 2014	22	21	6
Apr 2014	16	13	5
May 2014	21	21	8
Jun 2014	25	12	6
Jul 2014	22	21	2
Aug 2014	10	20	5
Sep 2014	18	18	2
Oct 2014	22	11	5
Nov 2014	17	11	2
Dec 2014	13	15	3
Jan 2015	7	1	2
Feb 2015	18	5	5
Mar 2015	15	11	7
Apr 2015	20	4	4
May 2015	18	7	5
Jun 2015	21	8	4
Jul 2015	6	10	8
Aug 2015	6	11	5
Sep 2015	23	16	9
Oct 2015	10	19	9
Nov 2015	12	3	4
Dec 2015	7	3	2
Jan 2016	4	4	3
Feb 2016	3	5	6
Mar 2016	13	4	8
Apr 2016	11	3	5
May 2016	25	10	4
Jun 2016	6	12	5
Jul 2016	9	10	11
Aug 2016	6	11	3
Sep 2016	5	8	11
Oct 2016	6	13	4
Nov 2016	1	16	10
Dec 2016	0	12	8
Jan 2017	0	26	16
Feb 2017	1	19	8
Mar 2017	0	20	2
Apr 2017	0	17	3
May 2017	7	18	2
Jun 2017	3	13	6
Jul 2017	4	12	0
Aug 2017	4	21	8
Sep 2017	1	15	10
Oct 2017	1	26	12
Nov 2017	6	30	8
Dec 2017	6	14	3
Jan 2018	4	28	6
Feb 2018	0	22	8
Mar 2018	1	31	9
Apr 2018	0	27	9
May 2018	0	33	11
Jun 2018	1	43	7
Jul 2018	1	28	7
Aug 2018	1	16	6
Sep 2018	1	18	3
Oct 2018	1	12	6
Nov 2018	0	21	10
Dec 2018	12	5	3
Jan 2019	13	2	0
Feb 2019	10	5	4
Mar 2019	29	2	1
Apr 2019	15	3	2
May 2019	14	1	4
Jun 2019	14	1	1
Jul 2019	12	4	1
Aug 2019	16	3	0
Sep 2019	28	0	0
Oct 2019	23	3	6
Nov 2019	31	2	2
Dec 2019	18	1	1
Jan 2020	13	0	0
Feb 2020	18	3	0
Mar 2020	7	0	0
Apr 2020	12	1	1
May 2020	48	3	3
Jun 2020	5	3	2
Jul 2020	12	1	2
Aug 2020	10	0	0
Sep 2020	16	2	4
Oct 2020	23	0	0
Nov 2020	7	1	1