Advertisement
Research ArticleArticle

SUBSTRATE DEPLETION APPROACH FOR DETERMINING IN VITRO METABOLIC CLEARANCE: TIME DEPENDENCIES IN HEPATOCYTE AND MICROSOMAL INCUBATIONS

Hannah M. Jones and J. Brian Houston
Drug Metabolism and Disposition September 2004, 32 (9) 973-982; DOI: https://doi.org/10.1124/dmd.104.000125

Article Information

vol. 32 no. 9 973-982
DOI 
https://doi.org/10.1124/dmd.104.000125
PubMed 
15319339
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 7, 2004
  • Accepted June 8, 2004
  • Published online August 18, 2004.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Hannah M. Jones1 and
  2. J. Brian Houston
  1. Centre for Applied Pharmaceutical Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom
  1. Address correspondence to:
    Professor J. Brian Houston, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester, M13 9PL, UK. E-mail: brian.houston{at}man.ac.uk
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: August 2017 to October 2023

AbstractFullPdf
Aug 201724634
Sep 201724721
Oct 201726043
Nov 201707129
Dec 201734411
Jan 201825124
Feb 201864353
Mar 201806343
Apr 201805225
May 201804733
Jun 201805938
Jul 201804635
Aug 201802722
Sep 201803420
Oct 201803846
Nov 201809396
Dec 2018414335
Jan 2019571425
Feb 201934129
Mar 2019532124
Apr 2019481310
May 2019412914
Jun 2019421110
Jul 201956510
Aug 20193076
Oct 2019291616
Nov 2019601518
Dec 2019364619
Jan 2020531919
Feb 202054138
Mar 202040125
May 20204559
Jun 202040125
Jul 20204897
Aug 20202256
Sep 202039814
Oct 20202285
Nov 20203245
Dec 2020381110
Jan 2021353716
Feb 202128256
Mar 2021321311
Apr 20215255
May 202129136
Jun 2021282310
Jul 202132126
Aug 202127165
Sep 2021331513
Oct 20213955
Nov 202145913
Dec 202140134
Jan 2022381014
Feb 20222865
Mar 2022651418
Apr 2022311314
May 2022281013
Jun 20224683
Jul 20223889
Aug 2022481514
Sep 2022451413
Oct 2022452521
Nov 20223156
Dec 20224157
Jan 202352138
Feb 202341710
Mar 20236796
Apr 20233198
May 202364309
Jun 20233298
Jul 202329135
Aug 202325154
Sep 20232775
Oct 2023700

Back to top

In this issue

Download PDF
Article Alerts
Email Article
Citation Tools

Research ArticleArticle

SUBSTRATE DEPLETION APPROACH FOR DETERMINING IN VITRO METABOLIC CLEARANCE: TIME DEPENDENCIES IN HEPATOCYTE AND MICROSOMAL INCUBATIONS

Hannah M. Jones and J. Brian Houston
Drug Metabolism and Disposition September 1, 2004, 32 (9) 973-982; DOI: https://doi.org/10.1124/dmd.104.000125
Reddit logo Twitter logo Facebook logo Mendeley logo

Jump to section

Advertisement