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Drug Metabolism & Disposition

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Table of Contents

January 01, 2005; Volume 33,Issue 1

Commentary

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    THE ROLES OF TRANSPORTERS AND ENZYMES IN HEPATIC DRUG PROCESSING
    Lichuan Liu and K. Sandy Pang
    Drug Metabolism and Disposition January 2005, 33 (1) 1-9; DOI: https://doi.org/10.1124/dmd.104.001149

The 2004 Bernard B. Brodie Award Lecture

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    STRUCTURAL AND FUNCTIONAL DIVERSITY IN HEME MONOOXYGENASES
    Thomas L. Poulos
    Drug Metabolism and Disposition January 2005, 33 (1) 10-18; DOI: https://doi.org/10.1124/dmd.104.002071

Short Communication

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    LACK OF EVIDENCE FOR INDUCTION OF CYP2B1, CYP3A23, AND CYP1A2 GENE EXPRESSION BY Panax ginseng AND Panax quinquefolius EXTRACTS IN ADULT RATS AND PRIMARY CULTURES OF RAT HEPATOCYTES
    Chia-ting Yu, Jie Chen, Xiao Wei Teng, Vincent Tong and Thomas K. H. Chang
    Drug Metabolism and Disposition January 2005, 33 (1) 19-22; DOI: https://doi.org/10.1124/dmd.104.001917

Articles

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    TRANS-3′-HYDROXYCOTININE O- AND N-GLUCURONIDATIONS IN HUMAN LIVER MICROSOMES
    Hiroyuki Yamanaka, Miki Nakajima, Miki Katoh, Ayano Kanoh, Osamu Tamura, Hiroyuki Ishibashi and Tsuyoshi Yokoi
    Drug Metabolism and Disposition January 2005, 33 (1) 23-30; DOI: https://doi.org/10.1124/dmd.104.001701
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    EXPRESSION, LOCALIZATION, AND FUNCTION OF THE CARNITINE TRANSPORTER OCTN2 (SLC22A5) IN HUMAN PLACENTA
    Markus Grube, Henriette Meyer zu Schwabedissen, Katrin Draber, Damaris Präger, Klaus-Uwe Möritz, Knud Linnemann, Christoph Fusch, Gabriele Jedlitschky and Heyo K. Kroemer
    Drug Metabolism and Disposition January 2005, 33 (1) 31-37; DOI: https://doi.org/10.1124/dmd.104.001560
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    HIGH VOLUME BIOASSAYS TO ASSESS CYP3A4-MEDIATED DRUG INTERACTIONS: INDUCTION AND INHIBITION IN A SINGLE CELL LINE
    Mei-Fei Yueh, Marleen Kawahara and Judy Raucy
    Drug Metabolism and Disposition January 2005, 33 (1) 38-48; DOI: https://doi.org/10.1124/dmd.104.001594
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    PHARMACOKINETICS AND METABOLISM OF APIGENIN IN FEMALE AND MALE RATS AFTER A SINGLE ORAL ADMINISTRATION
    Angéline Gradolatto, Jean-Philippe Basly, Raymond Berges, Caroline Teyssier, Marie-Christine Chagnon, Marie-Héléne Siess and Marie-Chantal Canivenc-Lavier
    Drug Metabolism and Disposition January 2005, 33 (1) 49-54; DOI: https://doi.org/10.1124/dmd.104.000893
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    BISPHENOL A GLUCURONIDATION AND EXCRETION IN LIVER OF PREGNANT AND NONPREGNANT FEMALE RATS
    Hiroki Inoue, Akio Tsuruta, Satoko Kudo, Takako Ishii, Yusuke Fukushima, Hidetomo Iwano, Hiroshi Yokota and Seiyu Kato
    Drug Metabolism and Disposition January 2005, 33 (1) 55-59; DOI: https://doi.org/10.1124/dmd.104.001537
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    CHARACTERIZATION OF AFLOQUALONE N-GLUCURONIDATION: SPECIES DIFFERENCES AND IDENTIFICATION OF HUMAN UDP-GLUCURONOSYLTRANSFERASE ISOFORM(S)
    Hidefumi Kaji and Toshiyuki Kume
    Drug Metabolism and Disposition January 2005, 33 (1) 60-67; DOI: https://doi.org/10.1124/dmd.104.001925
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    THE CONTRIBUTION OF FETAL METABOLISM TO THE DISPOSITION OF MORPHINE
    Marianne Garland, Kirsten M. Abildskov, Tung-wah Kiu, Salha S. Daniel and Raymond I. Stark
    Drug Metabolism and Disposition January 2005, 33 (1) 68-76; DOI: https://doi.org/10.1124/dmd.104.001388
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    ANALYSIS OF SUBSTRATE SPECIFICITIES AND TISSUE EXPRESSION OF RAT UDP-GLUCURONOSYLTRANSFERASES UGT1A7 AND UGT1A8
    Laura J. Webb, Kristini K. Miles, Diana J. Auyeung, Fay K. Kessler and Joseph K. Ritter
    Drug Metabolism and Disposition January 2005, 33 (1) 77-82; DOI: https://doi.org/10.1124/dmd.104.001321
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    METABOLISM, PHARMACOKINETICS, AND PROTEIN COVALENT BINDING OF RADIOLABELED MAXIPOST (BMS-204352) IN HUMANS
    Donglu Zhang, Rajesh Krishna, Lifei Wang, Jianing Zeng, James Mitroka, Renke Dai, Narayanan Narasimhan, Richard A. Reeves, Nuggehally R. Srinivas and Lewis J. Klunk
    Drug Metabolism and Disposition January 2005, 33 (1) 83-93; DOI: https://doi.org/10.1124/dmd.104.001412
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    FUNCTIONAL ASSESSMENT OF ABCG2 (BCRP) GENE POLYMORPHISMS TO PROTEIN EXPRESSION IN HUMAN PLACENTA
    Daisuke Kobayashi, Ichiro Ieiri, Takeshi Hirota, Hiroshi Takane, Shinji Maegawa, Junzo Kigawa, Hiroshi Suzuki, Eiji Nanba, Mitsuo Oshimura, Naoki Terakawa, Kenji Otsubo, Kazunori Mine and Yuichi Sugiyama
    Drug Metabolism and Disposition January 2005, 33 (1) 94-101; DOI: https://doi.org/10.1124/dmd.104.001628
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    METABOLISM OF 26,26,26,27,27,27-F6-1α,23S,25-TRIHYDROXYVITAMIN D3 BY HUMAN UDP-GLUCURONOSYLTRANSFERASE 1A3*
    Noriyuki Kasai, Toshiyuki Sakaki, Raku Shinkyo, Shin-ichi Ikushiro, Takashi Iyanagi, Miho Ohta and Kuniyo Inouye
    Drug Metabolism and Disposition January 2005, 33 (1) 102-107; DOI: https://doi.org/10.1124/dmd.104.002303
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    LIVER GRAFTS PRESERVED IN CELSIOR SOLUTION AS SOURCE OF HEPATOCYTES FOR DRUG METABOLISM STUDIES: COMPARISON WITH SURGICAL LIVER BIOPSIES
    M. Teresa Donato, Alfonso Serralta, Nuria Jiménez, Gabriela Pérez, José V. Castell, José Mir and M. José Gómez-Lechón
    Drug Metabolism and Disposition January 2005, 33 (1) 108-114; DOI: https://doi.org/10.1124/dmd.104.001545
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    PREDICTION OF IN VITRO INTRINSIC CLEARANCE FROM HEPATOCYTES: COMPARISON OF SUSPENSIONS AND MONOLAYER CULTURES
    Sarah J. Griffin and J. Brian Houston
    Drug Metabolism and Disposition January 2005, 33 (1) 115-120; DOI: https://doi.org/10.1124/dmd.33.1.115
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    METABOLIC ACTIVATION OF FLUOROPYRROLIDINE DIPEPTIDYL PEPTIDASE-IV INHIBITORS BY RAT LIVER MICROSOMES
    Shiyao Xu, Bing Zhu, Yohannes Teffera, Deborah E. Pan, Charles G. Caldwell, George Doss, Ralph A. Stearns, David C. Evans and Maria G. Beconi
    Drug Metabolism and Disposition January 2005, 33 (1) 121-130; DOI: https://doi.org/10.1124/dmd.104.001842
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    TIME-DEPENDENT INHIBITION AND TETRAHYDROBIOPTERIN DEPLETION OF ENDOTHELIAL NITRIC-OXIDE SYNTHASE CAUSED BY CIGARETTES
    Ezra R. Lowe, Andrew C. Everett, Anthony J. Lee, Miranda Lau, Anwar Y. Dunbar, Vladimir Berka, Ah-lim Tsai and Yoichi Osawa
    Drug Metabolism and Disposition January 2005, 33 (1) 131-138; DOI: https://doi.org/10.1124/dmd.104.001891
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    IDENTIFICATION OF THE UDP-GLUCURONOSYLTRANSFERASE ISOFORMS INVOLVED IN MYCOPHENOLIC ACID PHASE II METABOLISM
    Nicolas Picard, Damrong Ratanasavanh, Aurélie Prémaud, Yonnick Le Meur and Pierre Marquet
    Drug Metabolism and Disposition January 2005, 33 (1) 139-146; DOI: https://doi.org/10.1124/dmd.104.001651
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    REGULATION OF GLUCOCORTICOID-INDUCIBLE HYDROXYSTEROID SULFOTRANSFERASE (SULT2A-40/41) GENE TRANSCRIPTION IN PRIMARY CULTURED RAT HEPATOCYTES: ROLE OF CCAAT/ENHANCER-BINDING PROTEIN LIVER-ENRICHED TRANSCRIPTION FACTORS
    Hai-Lin Fang, Masumeh Abdolalipour, Zhengbo Duanmu, Jeffrey R. Smigelski, Amy Weckle, Thomas A. Kocarek and Melissa Runge-Morris
    Drug Metabolism and Disposition January 2005, 33 (1) 147-156; DOI: https://doi.org/10.1124/dmd.104.000281
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    INTERACTIONS BETWEEN CYP2C9 AND CYP2C19 IN RECONSTITUTED BINARY SYSTEMS INFLUENCE THEIR CATALYTIC ACTIVITY: POSSIBLE RATIONALE FOR THE INABILITY OF CYP2C19 TO CATALYZE METHOXYCHLOR DEMETHYLATION IN HUMAN LIVER MICROSOMES
    Eszter Hazai and David Kupfer
    Drug Metabolism and Disposition January 2005, 33 (1) 157-164; DOI: https://doi.org/10.1124/dmd.104.001578
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    THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL
    Angela Doran, R. Scott Obach, Bill J. Smith, Natilie A. Hosea, Stacey Becker, Ernesto Callegari, Cuiping Chen, Xi Chen, Edna Choo, Julie Cianfrogna, Loretta M. Cox, John P. Gibbs, Megan A. Gibbs, Heather Hatch, Cornelis E.C.A. Hop, Ilana N. Kasman, Jennifer LaPerle, JianHua Liu, Xingrong Liu, Michael Logman, Debra Maclin, Frank M. Nedza, Frederick Nelson, Emily Olson, Sandhya Rahematpura, David Raunig, Sabrinia Rogers, Kari Schmidt, Douglas K. Spracklin, Mark Szewc, Matthew Troutman, Elaine Tseng, Meihua Tu, Jeffrey W. Van Deusen, Karthik Venkatakrishnan, Gary Walens, Ellen Q. Wang, Diane Wong, Adam S. Yasgar and Chenghong Zhang
    Drug Metabolism and Disposition January 2005, 33 (1) 165-174; DOI: https://doi.org/10.1124/dmd.104.001230
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    RELATIONSHIP BETWEEN EXPOSURE AND NONSPECIFIC BINDING OF THIRTY-THREE CENTRAL NERVOUS SYSTEM DRUGS IN MICE
    Tristan S. Maurer, Demetria B. DeBartolo, David A. Tess and Dennis O. Scott
    Drug Metabolism and Disposition January 2005, 33 (1) 175-181; DOI: https://doi.org/10.1124/dmd.104.001222
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    XENOBIOTIC AND ENDOBIOTIC TRANSPORTER MRNA EXPRESSION IN THE BLOOD-TESTIS BARRIER
    Lisa M. Augustine, Robert J. Markelewicz, Kim Boekelheide and Nathan J. Cherrington
    Drug Metabolism and Disposition January 2005, 33 (1) 182-189; DOI: https://doi.org/10.1124/dmd.104.001024
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    METABOLISM, PHARMACOKINETICS, TISSUE DISTRIBUTION, AND EXCRETION OF [14C]CP-424391 IN RATS
    S. Cyrus Khojasteh-Bakht, John P. O'Donnell, Hassan G. Fouda and Michael J. Potchoiba
    Drug Metabolism and Disposition January 2005, 33 (1) 190-199; DOI: https://doi.org/10.1124/dmd.104.001065

Erratum

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    CORRECTION TO “TISSUE DISTRIBUTION, STABILITY, AND PHARMACOKINETICS OF APO2 LIGAND/TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGAND IN HUMAN COLON CARCINOMA COLO205 TUMOR-BEARING MICE”
    Drug Metabolism and Disposition January 2005, 33 (1) 200-201; DOI: https://doi.org/10.1124/dmd.33.1.200
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Drug Metabolism and Disposition: 33 (1)
Drug Metabolism and Disposition
Vol. 33, Issue 1
1 Jan 2005
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