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Research ArticleArticle

AUTOMATED ASSESSMENT OF TIME-DEPENDENT INHIBITION OF HUMAN CYTOCHROME P450 ENZYMES USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY ANALYSIS

Anthony Atkinson, Jane R. Kenny and Ken Grime
Drug Metabolism and Disposition November 2005, 33 (11) 1637-1647; DOI: https://doi.org/10.1124/dmd.105.005579

Article Information

vol. 33 no. 11 1637-1647
DOI 
https://doi.org/10.1124/dmd.105.005579
PubMed 
16049126
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 23, 2005
  • Accepted July 26, 2005
  • Published online October 26, 2005.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Anthony Atkinson,
  2. Jane R. Kenny and
  3. Ken Grime
  1. Department of Physical and Metabolic Science, AstraZeneca R&D Charnwood, Loughborough, United Kingdom
  1. Address correspondence to:
    Ken Grime, Department of Physical and Metabolic Science, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, LE11 5RH, UK. E-mail: ken.grime{at}astrazeneca.com
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Research ArticleArticle

AUTOMATED ASSESSMENT OF TIME-DEPENDENT INHIBITION OF HUMAN CYTOCHROME P450 ENZYMES USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY ANALYSIS

Anthony Atkinson, Jane R. Kenny and Ken Grime
Drug Metabolism and Disposition November 1, 2005, 33 (11) 1637-1647; DOI: https://doi.org/10.1124/dmd.105.005579
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