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Research ArticleArticle

PREDICTION OF CYP2C9-MEDIATED DRUG-DRUG INTERACTIONS: A COMPARISON USING DATA FROM RECOMBINANT ENZYMES AND HUMAN HEPATOCYTES

Dermot F. McGinnity, James Tucker, Steve Trigg and Robert J. Riley
Drug Metabolism and Disposition November 2005, 33 (11) 1700-1707; DOI: https://doi.org/10.1124/dmd.105.005884

Article Information

vol. 33 no. 11 1700-1707
DOI 
https://doi.org/10.1124/dmd.105.005884
PubMed 
16081671
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 1, 2005
  • Accepted August 3, 2005
  • Published online October 26, 2005.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Dermot F. McGinnity,
  2. James Tucker,
  3. Steve Trigg and
  4. Robert J. Riley
  1. Department of Physical & Metabolic Science, AstraZeneca R&D Charnwood, Bakewell Rd., Loughborough, Leicestershire, United Kingdom
  1. Address correspondence to:
    Dr. Dermot McGinnity, Department of Physical & Metabolic Science, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leicestershire, LE11 5RH, UK. E-mail: dermot.f.mcginnity{at}astrazeneca.com
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Research ArticleArticle

PREDICTION OF CYP2C9-MEDIATED DRUG-DRUG INTERACTIONS: A COMPARISON USING DATA FROM RECOMBINANT ENZYMES AND HUMAN HEPATOCYTES

Dermot F. McGinnity, James Tucker, Steve Trigg and Robert J. Riley
Drug Metabolism and Disposition November 1, 2005, 33 (11) 1700-1707; DOI: https://doi.org/10.1124/dmd.105.005884
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