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Index by author

December 01, 2005; Volume 33,Issue 12

A

  1. Anbazhagan, Mariappan

    1. UNUSUAL DEHYDROXYLATION OF ANTIMICROBIAL AMIDOXIME PRODRUGS BY CYTOCHROME b5 AND NADH CYTOCHROME b5 REDUCTASE
      Janelle Y. Saulter, Joseph R. Kurian, Lauren A. Trepanier, Richard R. Tidwell, Arlene S. Bridges, David W. Boykin, Chad E. Stephens, Mariappan Anbazhagan and James Edwin Hall
      Drug Metabolism and Disposition December 2005, 33 (12) 1886-1893; DOI: https://doi.org/10.1124/dmd.105.005017

  2. Ando, Yuichi

    1. GEFITINIB (IRESSA) INHIBITS THE CYP3A4-MEDIATED FORMATION OF 7-ETHYL-10-(4-AMINO-1-PIPERIDINO)CARBONYLOXYCAMPTOTHECIN BUT ACTIVATES THAT OF 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO]CARBONYLOXYCAMPTOTHECIN FROM IRINOTECAN
      Ken-ichi Fujita, Yuichi Ando, Masaru Narabayashi, Toshimichi Miya, Fumio Nagashima, Wataru Yamamoto, Keiji Kodama, Kazuhiro Araki, Hisashi Endo and Yasutsuna Sasaki
      Drug Metabolism and Disposition December 2005, 33 (12) 1785-1790; DOI: https://doi.org/10.1124/dmd.105.006205

  3. Anraku, Makoto

    1. HYDROLYSIS OF ANGIOTENSIN II RECEPTOR BLOCKER PRODRUG OLMESARTAN MEDOXOMIL BY HUMAN SERUM ALBUMIN AND IDENTIFICATION OF ITS CATALYTIC ACTIVE SITES
      Shen-Feng Ma, Makoto Anraku, Yasunori Iwao, Keishi Yamasaki, Ulrich Kragh-Hansen, Noriyuki Yamaotsu, Shuichi Hirono, Toshihiko Ikeda and Masaki Otagiri
      Drug Metabolism and Disposition December 2005, 33 (12) 1911-1919; DOI: https://doi.org/10.1124/dmd.105.006163

  4. Aoki, Yasuhiro

    1. CYP2A6 AND CYP2B6 ARE INVOLVED IN NORNICOTINE FORMATION FROM NICOTINE IN HUMANS: INTERINDIVIDUAL DIFFERENCES IN THESE CONTRIBUTIONS
      Hiroyuki Yamanaka, Miki Nakajima, Tatsuki Fukami, Haruko Sakai, Akiko Nakamura, Miki Katoh, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2005, 33 (12) 1811-1818; DOI: https://doi.org/10.1124/dmd.105.006254

  5. Araki, Kazuhiro

    1. GEFITINIB (IRESSA) INHIBITS THE CYP3A4-MEDIATED FORMATION OF 7-ETHYL-10-(4-AMINO-1-PIPERIDINO)CARBONYLOXYCAMPTOTHECIN BUT ACTIVATES THAT OF 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO]CARBONYLOXYCAMPTOTHECIN FROM IRINOTECAN
      Ken-ichi Fujita, Yuichi Ando, Masaru Narabayashi, Toshimichi Miya, Fumio Nagashima, Wataru Yamamoto, Keiji Kodama, Kazuhiro Araki, Hisashi Endo and Yasutsuna Sasaki
      Drug Metabolism and Disposition December 2005, 33 (12) 1785-1790; DOI: https://doi.org/10.1124/dmd.105.006205

B

  1. Bajimaya, Susan

    1. DISPOSITION OF FLAVONOIDS VIA RECYCLING: COMPARISON OF INTESTINAL VERSUS HEPATIC DISPOSITION
      Jun Chen, Stephen Wang, Xiaobin Jia, Susan Bajimaya, Huimin Lin, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition December 2005, 33 (12) 1777-1784; DOI: https://doi.org/10.1124/dmd.105.003673

  2. Beaune, Philippe

    1. SIMULTANEOUS MEASUREMENT OF 23 ISOFORMS FROM THE HUMAN CYTOCHROME P450 FAMILIES 1 TO 3 BY QUANTITATIVE REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION
      Igor Girault, Nathalie Rougier, Christophe Chesné, Rosette Lidereau, Philippe Beaune, Ivan Bieche and Isabelle de Waziers
      Drug Metabolism and Disposition December 2005, 33 (12) 1803-1810; DOI: https://doi.org/10.1124/dmd.105.005173

  3. Bieche, Ivan

    1. SIMULTANEOUS MEASUREMENT OF 23 ISOFORMS FROM THE HUMAN CYTOCHROME P450 FAMILIES 1 TO 3 BY QUANTITATIVE REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION
      Igor Girault, Nathalie Rougier, Christophe Chesné, Rosette Lidereau, Philippe Beaune, Ivan Bieche and Isabelle de Waziers
      Drug Metabolism and Disposition December 2005, 33 (12) 1803-1810; DOI: https://doi.org/10.1124/dmd.105.005173

  4. Boykin, David W.

    1. UNUSUAL DEHYDROXYLATION OF ANTIMICROBIAL AMIDOXIME PRODRUGS BY CYTOCHROME b5 AND NADH CYTOCHROME b5 REDUCTASE
      Janelle Y. Saulter, Joseph R. Kurian, Lauren A. Trepanier, Richard R. Tidwell, Arlene S. Bridges, David W. Boykin, Chad E. Stephens, Mariappan Anbazhagan and James Edwin Hall
      Drug Metabolism and Disposition December 2005, 33 (12) 1886-1893; DOI: https://doi.org/10.1124/dmd.105.005017

  5. Bräter, M.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  6. Bridges, Arlene S.

    1. UNUSUAL DEHYDROXYLATION OF ANTIMICROBIAL AMIDOXIME PRODRUGS BY CYTOCHROME b5 AND NADH CYTOCHROME b5 REDUCTASE
      Janelle Y. Saulter, Joseph R. Kurian, Lauren A. Trepanier, Richard R. Tidwell, Arlene S. Bridges, David W. Boykin, Chad E. Stephens, Mariappan Anbazhagan and James Edwin Hall
      Drug Metabolism and Disposition December 2005, 33 (12) 1886-1893; DOI: https://doi.org/10.1124/dmd.105.005017

  7. Bu, Hai-Zhi

    1. HUMAN IN VITRO GLUTATHIONYL AND PROTEIN ADDUCTS OF CARBAMAZEPINE-10,11-EPOXIDE, A STABLE AND PHARMACOLOGICALLY ACTIVE METABOLITE OF CARBAMAZEPINE
      Hai-Zhi Bu, Ping Kang, Alan J. Deese, Ping Zhao and William F. Pool
      Drug Metabolism and Disposition December 2005, 33 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.105.006866

C

  1. Caldwell, Gary W.

    1. BIOACTIVATION OF 4-METHYLPHENOL (p-CRESOL) VIA CYTOCHROME P450-MEDIATED AROMATIC OXIDATION IN HUMAN LIVER MICROSOMES
      Zhengyin Yan, H. Marlon Zhong, Noureddine Maher, Rhoda Torres, Gregory C. Leo, Gary W. Caldwell and Norman Huebert
      Drug Metabolism and Disposition December 2005, 33 (12) 1867-1876; DOI: https://doi.org/10.1124/dmd.105.006387

  2. Cato, Brian

    1. SPECIES DIFFERENCES IN THE ELIMINATION OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST HIGHLIGHTED BY OXIDATIVE METABOLISM OF ITS ACYL GLUCURONIDE
      Christopher J. Kochansky, Yuan-Qing Xia, Sui Wang, Brian Cato, Mellissa Creighton, Stella H. Vincent, Ronald B. Franklin and James R. Reed
      Drug Metabolism and Disposition December 2005, 33 (12) 1894-1904; DOI: https://doi.org/10.1124/dmd.105.004010

  3. Chen, Jun

    1. DISPOSITION OF FLAVONOIDS VIA RECYCLING: COMPARISON OF INTESTINAL VERSUS HEPATIC DISPOSITION
      Jun Chen, Stephen Wang, Xiaobin Jia, Susan Bajimaya, Huimin Lin, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition December 2005, 33 (12) 1777-1784; DOI: https://doi.org/10.1124/dmd.105.003673

  4. Chesné, Christophe

    1. SIMULTANEOUS MEASUREMENT OF 23 ISOFORMS FROM THE HUMAN CYTOCHROME P450 FAMILIES 1 TO 3 BY QUANTITATIVE REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION
      Igor Girault, Nathalie Rougier, Christophe Chesné, Rosette Lidereau, Philippe Beaune, Ivan Bieche and Isabelle de Waziers
      Drug Metabolism and Disposition December 2005, 33 (12) 1803-1810; DOI: https://doi.org/10.1124/dmd.105.005173

  5. Chilakapati, Jaya

    1. SATURATION TOXICOKINETICS OF THIOACETAMIDE: ROLE IN INITIATION OF LIVER INJURY
      Jaya Chilakapati, Kartik Shankar, Midhun C. Korrapati, Ronald A. Hill and Harihara M. Mehendale
      Drug Metabolism and Disposition December 2005, 33 (12) 1877-1885; DOI: https://doi.org/10.1124/dmd.105.005520

  6. Chun, Young-Jin

    1. MODULATION OF HUMAN CYTOCHROME P450 1B1 EXPRESSION BY 2,4,3′,5′-TETRAMETHOXYSTILBENE
      Young-Jin Chun, Sang-Kwang Lee and Mie Young Kim
      Drug Metabolism and Disposition December 2005, 33 (12) 1771-1776; DOI: https://doi.org/10.1124/dmd.105.006502

  7. Court, Michael H.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

  8. Creighton, Mellissa

    1. SPECIES DIFFERENCES IN THE ELIMINATION OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST HIGHLIGHTED BY OXIDATIVE METABOLISM OF ITS ACYL GLUCURONIDE
      Christopher J. Kochansky, Yuan-Qing Xia, Sui Wang, Brian Cato, Mellissa Creighton, Stella H. Vincent, Ronald B. Franklin and James R. Reed
      Drug Metabolism and Disposition December 2005, 33 (12) 1894-1904; DOI: https://doi.org/10.1124/dmd.105.004010

  9. Cui, Donghui

    1. TRANSAMINATION IN THE METABOLISM OF THE NEPHROTOXICANT N-(3,5-DICHLOROPHENYL)SUCCINIMIDE IN RATS
      Donghui Cui, Gary O. Rankin and Peter J. Harvison
      Drug Metabolism and Disposition December 2005, 33 (12) 1765-1770; DOI: https://doi.org/10.1124/dmd.105.006593

D

  1. Deese, Alan J.

    1. HUMAN IN VITRO GLUTATHIONYL AND PROTEIN ADDUCTS OF CARBAMAZEPINE-10,11-EPOXIDE, A STABLE AND PHARMACOLOGICALLY ACTIVE METABOLITE OF CARBAMAZEPINE
      Hai-Zhi Bu, Ping Kang, Alan J. Deese, Ping Zhao and William F. Pool
      Drug Metabolism and Disposition December 2005, 33 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.105.006866

  2. de Waziers, Isabelle

    1. SIMULTANEOUS MEASUREMENT OF 23 ISOFORMS FROM THE HUMAN CYTOCHROME P450 FAMILIES 1 TO 3 BY QUANTITATIVE REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION
      Igor Girault, Nathalie Rougier, Christophe Chesné, Rosette Lidereau, Philippe Beaune, Ivan Bieche and Isabelle de Waziers
      Drug Metabolism and Disposition December 2005, 33 (12) 1803-1810; DOI: https://doi.org/10.1124/dmd.105.005173

  3. Dicke, Kari E.

    1. NICOTINE AND 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-BUTANONE METABOLISM BY CYTOCHROME P450 2B6
      Kari E. Dicke, Sara M. Skrlin and Sharon E. Murphy
      Drug Metabolism and Disposition December 2005, 33 (12) 1760-1764; DOI: https://doi.org/10.1124/dmd.105.006718

  4. Doroshyenko, O.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  5. Duan, Su X.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

E

  1. Endo, Hisashi

    1. GEFITINIB (IRESSA) INHIBITS THE CYP3A4-MEDIATED FORMATION OF 7-ETHYL-10-(4-AMINO-1-PIPERIDINO)CARBONYLOXYCAMPTOTHECIN BUT ACTIVATES THAT OF 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO]CARBONYLOXYCAMPTOTHECIN FROM IRINOTECAN
      Ken-ichi Fujita, Yuichi Ando, Masaru Narabayashi, Toshimichi Miya, Fumio Nagashima, Wataru Yamamoto, Keiji Kodama, Kazuhiro Araki, Hisashi Endo and Yasutsuna Sasaki
      Drug Metabolism and Disposition December 2005, 33 (12) 1785-1790; DOI: https://doi.org/10.1124/dmd.105.006205

  2. Evans, Ronald M.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

F

  1. Frank, D.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  2. Franklin, Ronald B.

    1. SPECIES DIFFERENCES IN THE ELIMINATION OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST HIGHLIGHTED BY OXIDATIVE METABOLISM OF ITS ACYL GLUCURONIDE
      Christopher J. Kochansky, Yuan-Qing Xia, Sui Wang, Brian Cato, Mellissa Creighton, Stella H. Vincent, Ronald B. Franklin and James R. Reed
      Drug Metabolism and Disposition December 2005, 33 (12) 1894-1904; DOI: https://doi.org/10.1124/dmd.105.004010

  3. Fuhr, U.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  4. Fujita, Ken-ichi

    1. GEFITINIB (IRESSA) INHIBITS THE CYP3A4-MEDIATED FORMATION OF 7-ETHYL-10-(4-AMINO-1-PIPERIDINO)CARBONYLOXYCAMPTOTHECIN BUT ACTIVATES THAT OF 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO]CARBONYLOXYCAMPTOTHECIN FROM IRINOTECAN
      Ken-ichi Fujita, Yuichi Ando, Masaru Narabayashi, Toshimichi Miya, Fumio Nagashima, Wataru Yamamoto, Keiji Kodama, Kazuhiro Araki, Hisashi Endo and Yasutsuna Sasaki
      Drug Metabolism and Disposition December 2005, 33 (12) 1785-1790; DOI: https://doi.org/10.1124/dmd.105.006205

  5. Fukami, Tatsuki

    1. CYP2A6 AND CYP2B6 ARE INVOLVED IN NORNICOTINE FORMATION FROM NICOTINE IN HUMANS: INTERINDIVIDUAL DIFFERENCES IN THESE CONTRIBUTIONS
      Hiroyuki Yamanaka, Miki Nakajima, Tatsuki Fukami, Haruko Sakai, Akiko Nakamura, Miki Katoh, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2005, 33 (12) 1811-1818; DOI: https://doi.org/10.1124/dmd.105.006254

G

  1. Girault, Igor

    1. SIMULTANEOUS MEASUREMENT OF 23 ISOFORMS FROM THE HUMAN CYTOCHROME P450 FAMILIES 1 TO 3 BY QUANTITATIVE REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION
      Igor Girault, Nathalie Rougier, Christophe Chesné, Rosette Lidereau, Philippe Beaune, Ivan Bieche and Isabelle de Waziers
      Drug Metabolism and Disposition December 2005, 33 (12) 1803-1810; DOI: https://doi.org/10.1124/dmd.105.005173

  2. Gramatté, T.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  3. Greenblatt, David J.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

H

  1. Hakooz, Nancy

    1. PREDICTION OF METABOLIC CLEARANCE USING CRYOPRESERVED HUMAN HEPATOCYTES: KINETIC CHARACTERISTICS FOR FIVE BENZODIAZEPINES
      David Hallifax, Helen C. Rawden, Nancy Hakooz and J. Brian Houston
      Drug Metabolism and Disposition December 2005, 33 (12) 1852-1858; DOI: https://doi.org/10.1124/dmd.105.005389

  2. Hall, James Edwin

    1. UNUSUAL DEHYDROXYLATION OF ANTIMICROBIAL AMIDOXIME PRODRUGS BY CYTOCHROME b5 AND NADH CYTOCHROME b5 REDUCTASE
      Janelle Y. Saulter, Joseph R. Kurian, Lauren A. Trepanier, Richard R. Tidwell, Arlene S. Bridges, David W. Boykin, Chad E. Stephens, Mariappan Anbazhagan and James Edwin Hall
      Drug Metabolism and Disposition December 2005, 33 (12) 1886-1893; DOI: https://doi.org/10.1124/dmd.105.005017

  3. Hallifax, David

    1. PREDICTION OF METABOLIC CLEARANCE USING CRYOPRESERVED HUMAN HEPATOCYTES: KINETIC CHARACTERISTICS FOR FIVE BENZODIAZEPINES
      David Hallifax, Helen C. Rawden, Nancy Hakooz and J. Brian Houston
      Drug Metabolism and Disposition December 2005, 33 (12) 1852-1858; DOI: https://doi.org/10.1124/dmd.105.005389

  4. Halpert, James R.

    1. James R. Halpert
      Drug Metabolism and Disposition December 2005, 33 (12) 1759; DOI: https://doi.org/10.1124/dmd.33.12.1759

  5. Hanioka, Nobumitsu

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

  6. Hao, Qin

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

  7. Harlfinger, S.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  8. Harvison, Peter J.

    1. TRANSAMINATION IN THE METABOLISM OF THE NEPHROTOXICANT N-(3,5-DICHLOROPHENYL)SUCCINIMIDE IN RATS
      Donghui Cui, Gary O. Rankin and Peter J. Harvison
      Drug Metabolism and Disposition December 2005, 33 (12) 1765-1770; DOI: https://doi.org/10.1124/dmd.105.006593

  9. Hill, Ronald A.

    1. SATURATION TOXICOKINETICS OF THIOACETAMIDE: ROLE IN INITIATION OF LIVER INJURY
      Jaya Chilakapati, Kartik Shankar, Midhun C. Korrapati, Ronald A. Hill and Harihara M. Mehendale
      Drug Metabolism and Disposition December 2005, 33 (12) 1877-1885; DOI: https://doi.org/10.1124/dmd.105.005520

  10. Hirayama, Masamichi

    1. INVOLVEMENT OF URIC ACID TRANSPORTER IN INCREASED RENAL CLEARANCE OF THE XANTHINE OXIDASE INHIBITOR OXYPURINOL INDUCED BY A URICOSURIC AGENT, BENZBROMARONE
      Takashi Iwanaga, Daisuke Kobayashi, Masamichi Hirayama, Tomoji Maeda and Ikumi Tamai
      Drug Metabolism and Disposition December 2005, 33 (12) 1791-1795; DOI: https://doi.org/10.1124/dmd.105.006056

  11. Hirono, Shuichi

    1. HYDROLYSIS OF ANGIOTENSIN II RECEPTOR BLOCKER PRODRUG OLMESARTAN MEDOXOMIL BY HUMAN SERUM ALBUMIN AND IDENTIFICATION OF ITS CATALYTIC ACTIVE SITES
      Shen-Feng Ma, Makoto Anraku, Yasunori Iwao, Keishi Yamasaki, Ulrich Kragh-Hansen, Noriyuki Yamaotsu, Shuichi Hirono, Toshihiko Ikeda and Masaki Otagiri
      Drug Metabolism and Disposition December 2005, 33 (12) 1911-1919; DOI: https://doi.org/10.1124/dmd.105.006163

  12. Houston, J. Brian

    1. PREDICTION OF METABOLIC CLEARANCE USING CRYOPRESERVED HUMAN HEPATOCYTES: KINETIC CHARACTERISTICS FOR FIVE BENZODIAZEPINES
      David Hallifax, Helen C. Rawden, Nancy Hakooz and J. Brian Houston
      Drug Metabolism and Disposition December 2005, 33 (12) 1852-1858; DOI: https://doi.org/10.1124/dmd.105.005389

  13. Hu, Ming

    1. DISPOSITION OF FLAVONOIDS VIA RECYCLING: COMPARISON OF INTESTINAL VERSUS HEPATIC DISPOSITION
      Jun Chen, Stephen Wang, Xiaobin Jia, Susan Bajimaya, Huimin Lin, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition December 2005, 33 (12) 1777-1784; DOI: https://doi.org/10.1124/dmd.105.003673

  14. Huebert, Norman

    1. BIOACTIVATION OF 4-METHYLPHENOL (p-CRESOL) VIA CYTOCHROME P450-MEDIATED AROMATIC OXIDATION IN HUMAN LIVER MICROSOMES
      Zhengyin Yan, H. Marlon Zhong, Noureddine Maher, Rhoda Torres, Gregory C. Leo, Gary W. Caldwell and Norman Huebert
      Drug Metabolism and Disposition December 2005, 33 (12) 1867-1876; DOI: https://doi.org/10.1124/dmd.105.006387

  15. Hunt, Jane A.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

I

  1. Ikeda, Toshihiko

    1. HYDROLYSIS OF ANGIOTENSIN II RECEPTOR BLOCKER PRODRUG OLMESARTAN MEDOXOMIL BY HUMAN SERUM ALBUMIN AND IDENTIFICATION OF ITS CATALYTIC ACTIVE SITES
      Shen-Feng Ma, Makoto Anraku, Yasunori Iwao, Keishi Yamasaki, Ulrich Kragh-Hansen, Noriyuki Yamaotsu, Shuichi Hirono, Toshihiko Ikeda and Masaki Otagiri
      Drug Metabolism and Disposition December 2005, 33 (12) 1911-1919; DOI: https://doi.org/10.1124/dmd.105.006163

  2. Isobe, Takashi

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

  3. Iwanaga, Takashi

    1. INVOLVEMENT OF URIC ACID TRANSPORTER IN INCREASED RENAL CLEARANCE OF THE XANTHINE OXIDASE INHIBITOR OXYPURINOL INDUCED BY A URICOSURIC AGENT, BENZBROMARONE
      Takashi Iwanaga, Daisuke Kobayashi, Masamichi Hirayama, Tomoji Maeda and Ikumi Tamai
      Drug Metabolism and Disposition December 2005, 33 (12) 1791-1795; DOI: https://doi.org/10.1124/dmd.105.006056

  4. Iwao, Yasunori

    1. HYDROLYSIS OF ANGIOTENSIN II RECEPTOR BLOCKER PRODRUG OLMESARTAN MEDOXOMIL BY HUMAN SERUM ALBUMIN AND IDENTIFICATION OF ITS CATALYTIC ACTIVE SITES
      Shen-Feng Ma, Makoto Anraku, Yasunori Iwao, Keishi Yamasaki, Ulrich Kragh-Hansen, Noriyuki Yamaotsu, Shuichi Hirono, Toshihiko Ikeda and Masaki Otagiri
      Drug Metabolism and Disposition December 2005, 33 (12) 1911-1919; DOI: https://doi.org/10.1124/dmd.105.006163

J

  1. Jeffery, Elizabeth H.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

  2. Jetter, A.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  3. Jia, Xiaobin

    1. DISPOSITION OF FLAVONOIDS VIA RECYCLING: COMPARISON OF INTESTINAL VERSUS HEPATIC DISPOSITION
      Jun Chen, Stephen Wang, Xiaobin Jia, Susan Bajimaya, Huimin Lin, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition December 2005, 33 (12) 1777-1784; DOI: https://doi.org/10.1124/dmd.105.003673

  4. Jinno, Hideto

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

K

  1. Kang, Ping

    1. HUMAN IN VITRO GLUTATHIONYL AND PROTEIN ADDUCTS OF CARBAMAZEPINE-10,11-EPOXIDE, A STABLE AND PHARMACOLOGICALLY ACTIVE METABOLITE OF CARBAMAZEPINE
      Hai-Zhi Bu, Ping Kang, Alan J. Deese, Ping Zhao and William F. Pool
      Drug Metabolism and Disposition December 2005, 33 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.105.006866

  2. Kasel, D.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  3. Katoh, Miki

    1. CYP2A6 AND CYP2B6 ARE INVOLVED IN NORNICOTINE FORMATION FROM NICOTINE IN HUMANS: INTERINDIVIDUAL DIFFERENCES IN THESE CONTRIBUTIONS
      Hiroyuki Yamanaka, Miki Nakajima, Tatsuki Fukami, Haruko Sakai, Akiko Nakamura, Miki Katoh, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2005, 33 (12) 1811-1818; DOI: https://doi.org/10.1124/dmd.105.006254

  4. Kim, Mie Young

    1. MODULATION OF HUMAN CYTOCHROME P450 1B1 EXPRESSION BY 2,4,3′,5′-TETRAMETHOXYSTILBENE
      Young-Jin Chun, Sang-Kwang Lee and Mie Young Kim
      Drug Metabolism and Disposition December 2005, 33 (12) 1771-1776; DOI: https://doi.org/10.1124/dmd.105.006502

  5. Kinzig-Schippers, M.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  6. Kirchheiner, J.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  7. Klaassen, T.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  8. Kobayashi, Daisuke

    1. INVOLVEMENT OF URIC ACID TRANSPORTER IN INCREASED RENAL CLEARANCE OF THE XANTHINE OXIDASE INHIBITOR OXYPURINOL INDUCED BY A URICOSURIC AGENT, BENZBROMARONE
      Takashi Iwanaga, Daisuke Kobayashi, Masamichi Hirayama, Tomoji Maeda and Ikumi Tamai
      Drug Metabolism and Disposition December 2005, 33 (12) 1791-1795; DOI: https://doi.org/10.1124/dmd.105.006056

  9. Kobayashi, Yasuna

    1. FUNCTIONAL CHARACTERIZATION OF HUMAN MONOCARBOXYLATE TRANSPORTER 6 (SLC16A5)
      Yuichi Murakami, Noriko Kohyama, Yasuna Kobayashi, Masayuki Ohbayashi, Hisakazu Ohtani, Yasufumi Sawada and Toshinori Yamamoto
      Drug Metabolism and Disposition December 2005, 33 (12) 1845-1851; DOI: https://doi.org/10.1124/dmd.105.005264

  10. Kochansky, Christopher J.

    1. SPECIES DIFFERENCES IN THE ELIMINATION OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST HIGHLIGHTED BY OXIDATIVE METABOLISM OF ITS ACYL GLUCURONIDE
      Christopher J. Kochansky, Yuan-Qing Xia, Sui Wang, Brian Cato, Mellissa Creighton, Stella H. Vincent, Ronald B. Franklin and James R. Reed
      Drug Metabolism and Disposition December 2005, 33 (12) 1894-1904; DOI: https://doi.org/10.1124/dmd.105.004010

  11. Kodama, Keiji

    1. GEFITINIB (IRESSA) INHIBITS THE CYP3A4-MEDIATED FORMATION OF 7-ETHYL-10-(4-AMINO-1-PIPERIDINO)CARBONYLOXYCAMPTOTHECIN BUT ACTIVATES THAT OF 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO]CARBONYLOXYCAMPTOTHECIN FROM IRINOTECAN
      Ken-ichi Fujita, Yuichi Ando, Masaru Narabayashi, Toshimichi Miya, Fumio Nagashima, Wataru Yamamoto, Keiji Kodama, Kazuhiro Araki, Hisashi Endo and Yasutsuna Sasaki
      Drug Metabolism and Disposition December 2005, 33 (12) 1785-1790; DOI: https://doi.org/10.1124/dmd.105.006205

  12. Kohyama, Noriko

    1. FUNCTIONAL CHARACTERIZATION OF HUMAN MONOCARBOXYLATE TRANSPORTER 6 (SLC16A5)
      Yuichi Murakami, Noriko Kohyama, Yasuna Kobayashi, Masayuki Ohbayashi, Hisakazu Ohtani, Yasufumi Sawada and Toshinori Yamamoto
      Drug Metabolism and Disposition December 2005, 33 (12) 1845-1851; DOI: https://doi.org/10.1124/dmd.105.005264

  13. Korrapati, Midhun C.

    1. SATURATION TOXICOKINETICS OF THIOACETAMIDE: ROLE IN INITIATION OF LIVER INJURY
      Jaya Chilakapati, Kartik Shankar, Midhun C. Korrapati, Ronald A. Hill and Harihara M. Mehendale
      Drug Metabolism and Disposition December 2005, 33 (12) 1877-1885; DOI: https://doi.org/10.1124/dmd.105.005520

  14. Kragh-Hansen, Ulrich

    1. HYDROLYSIS OF ANGIOTENSIN II RECEPTOR BLOCKER PRODRUG OLMESARTAN MEDOXOMIL BY HUMAN SERUM ALBUMIN AND IDENTIFICATION OF ITS CATALYTIC ACTIVE SITES
      Shen-Feng Ma, Makoto Anraku, Yasunori Iwao, Keishi Yamasaki, Ulrich Kragh-Hansen, Noriyuki Yamaotsu, Shuichi Hirono, Toshihiko Ikeda and Masaki Otagiri
      Drug Metabolism and Disposition December 2005, 33 (12) 1911-1919; DOI: https://doi.org/10.1124/dmd.105.006163

  15. Kunze, Kent L.

    1. OXIDATION OF CAFFEINE BY CYP1A2: ISOTOPE EFFECTS AND METABOLIC SWITCHING
      Kelly A. Regal, Kent L. Kunze, Raimund M. Peter and Sidney D. Nelson
      Drug Metabolism and Disposition December 2005, 33 (12) 1837-1844; DOI: https://doi.org/10.1124/dmd.105.006031

  16. Kurian, Joseph R.

    1. UNUSUAL DEHYDROXYLATION OF ANTIMICROBIAL AMIDOXIME PRODRUGS BY CYTOCHROME b5 AND NADH CYTOCHROME b5 REDUCTASE
      Janelle Y. Saulter, Joseph R. Kurian, Lauren A. Trepanier, Richard R. Tidwell, Arlene S. Bridges, David W. Boykin, Chad E. Stephens, Mariappan Anbazhagan and James Edwin Hall
      Drug Metabolism and Disposition December 2005, 33 (12) 1886-1893; DOI: https://doi.org/10.1124/dmd.105.005017

L

  1. Lan, Lubin

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

  2. Lee, Sang-Kwang

    1. MODULATION OF HUMAN CYTOCHROME P450 1B1 EXPRESSION BY 2,4,3′,5′-TETRAMETHOXYSTILBENE
      Young-Jin Chun, Sang-Kwang Lee and Mie Young Kim
      Drug Metabolism and Disposition December 2005, 33 (12) 1771-1776; DOI: https://doi.org/10.1124/dmd.105.006502

  3. Leeder, J. Steven

    1. PATHWAYS OF CARBAMAZEPINE BIOACTIVATION IN VITRO: II. THE ROLE OF HUMAN CYTOCHROME P450 ENZYMES IN THE FORMATION OF 2-HYDROXYIMINOSTILBENE
      Robin E. Pearce, Jack P. Uetrecht and J. Steven Leeder
      Drug Metabolism and Disposition December 2005, 33 (12) 1819-1826; DOI: https://doi.org/10.1124/dmd.105.004861

  4. Leo, Gregory C.

    1. BIOACTIVATION OF 4-METHYLPHENOL (p-CRESOL) VIA CYTOCHROME P450-MEDIATED AROMATIC OXIDATION IN HUMAN LIVER MICROSOMES
      Zhengyin Yan, H. Marlon Zhong, Noureddine Maher, Rhoda Torres, Gregory C. Leo, Gary W. Caldwell and Norman Huebert
      Drug Metabolism and Disposition December 2005, 33 (12) 1867-1876; DOI: https://doi.org/10.1124/dmd.105.006387

  5. Lidereau, Rosette

    1. SIMULTANEOUS MEASUREMENT OF 23 ISOFORMS FROM THE HUMAN CYTOCHROME P450 FAMILIES 1 TO 3 BY QUANTITATIVE REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION
      Igor Girault, Nathalie Rougier, Christophe Chesné, Rosette Lidereau, Philippe Beaune, Ivan Bieche and Isabelle de Waziers
      Drug Metabolism and Disposition December 2005, 33 (12) 1803-1810; DOI: https://doi.org/10.1124/dmd.105.005173

  6. Lin, Huimin

    1. DISPOSITION OF FLAVONOIDS VIA RECYCLING: COMPARISON OF INTESTINAL VERSUS HEPATIC DISPOSITION
      Jun Chen, Stephen Wang, Xiaobin Jia, Susan Bajimaya, Huimin Lin, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition December 2005, 33 (12) 1777-1784; DOI: https://doi.org/10.1124/dmd.105.003673

M

  1. Ma, Bennett

    1. GLYCOSIDATION OF AN ENDOTHELIN ETA RECEPTOR ANTAGONIST AND DICLOFENAC IN HUMAN LIVER MICROSOMES: AGLYCONE-DEPENDENT UDP-SUGAR SELECTIVITY
      Cuyue Tang and Bennett Ma
      Drug Metabolism and Disposition December 2005, 33 (12) 1796-1802; DOI: https://doi.org/10.1124/dmd.105.005801

  2. Ma, Shen-Feng

    1. HYDROLYSIS OF ANGIOTENSIN II RECEPTOR BLOCKER PRODRUG OLMESARTAN MEDOXOMIL BY HUMAN SERUM ALBUMIN AND IDENTIFICATION OF ITS CATALYTIC ACTIVE SITES
      Shen-Feng Ma, Makoto Anraku, Yasunori Iwao, Keishi Yamasaki, Ulrich Kragh-Hansen, Noriyuki Yamaotsu, Shuichi Hirono, Toshihiko Ikeda and Masaki Otagiri
      Drug Metabolism and Disposition December 2005, 33 (12) 1911-1919; DOI: https://doi.org/10.1124/dmd.105.006163

  3. Maeda, Tomoji

    1. INVOLVEMENT OF URIC ACID TRANSPORTER IN INCREASED RENAL CLEARANCE OF THE XANTHINE OXIDASE INHIBITOR OXYPURINOL INDUCED BY A URICOSURIC AGENT, BENZBROMARONE
      Takashi Iwanaga, Daisuke Kobayashi, Masamichi Hirayama, Tomoji Maeda and Ikumi Tamai
      Drug Metabolism and Disposition December 2005, 33 (12) 1791-1795; DOI: https://doi.org/10.1124/dmd.105.006056

  4. Maekawa, Keiko

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

  5. Maher, Noureddine

    1. BIOACTIVATION OF 4-METHYLPHENOL (p-CRESOL) VIA CYTOCHROME P450-MEDIATED AROMATIC OXIDATION IN HUMAN LIVER MICROSOMES
      Zhengyin Yan, H. Marlon Zhong, Noureddine Maher, Rhoda Torres, Gregory C. Leo, Gary W. Caldwell and Norman Huebert
      Drug Metabolism and Disposition December 2005, 33 (12) 1867-1876; DOI: https://doi.org/10.1124/dmd.105.006387

  6. Mehendale, Harihara M.

    1. SATURATION TOXICOKINETICS OF THIOACETAMIDE: ROLE IN INITIATION OF LIVER INJURY
      Jaya Chilakapati, Kartik Shankar, Midhun C. Korrapati, Ronald A. Hill and Harihara M. Mehendale
      Drug Metabolism and Disposition December 2005, 33 (12) 1877-1885; DOI: https://doi.org/10.1124/dmd.105.005520

  7. Miya, Toshimichi

    1. GEFITINIB (IRESSA) INHIBITS THE CYP3A4-MEDIATED FORMATION OF 7-ETHYL-10-(4-AMINO-1-PIPERIDINO)CARBONYLOXYCAMPTOTHECIN BUT ACTIVATES THAT OF 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO]CARBONYLOXYCAMPTOTHECIN FROM IRINOTECAN
      Ken-ichi Fujita, Yuichi Ando, Masaru Narabayashi, Toshimichi Miya, Fumio Nagashima, Wataru Yamamoto, Keiji Kodama, Kazuhiro Araki, Hisashi Endo and Yasutsuna Sasaki
      Drug Metabolism and Disposition December 2005, 33 (12) 1785-1790; DOI: https://doi.org/10.1124/dmd.105.006205

  8. Murakami, Yuichi

    1. FUNCTIONAL CHARACTERIZATION OF HUMAN MONOCARBOXYLATE TRANSPORTER 6 (SLC16A5)
      Yuichi Murakami, Noriko Kohyama, Yasuna Kobayashi, Masayuki Ohbayashi, Hisakazu Ohtani, Yasufumi Sawada and Toshinori Yamamoto
      Drug Metabolism and Disposition December 2005, 33 (12) 1845-1851; DOI: https://doi.org/10.1124/dmd.105.005264

  9. Murphy, Sharon E.

    1. NICOTINE AND 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-BUTANONE METABOLISM BY CYTOCHROME P450 2B6
      Kari E. Dicke, Sara M. Skrlin and Sharon E. Murphy
      Drug Metabolism and Disposition December 2005, 33 (12) 1760-1764; DOI: https://doi.org/10.1124/dmd.105.006718

N

  1. Nagashima, Fumio

    1. GEFITINIB (IRESSA) INHIBITS THE CYP3A4-MEDIATED FORMATION OF 7-ETHYL-10-(4-AMINO-1-PIPERIDINO)CARBONYLOXYCAMPTOTHECIN BUT ACTIVATES THAT OF 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO]CARBONYLOXYCAMPTOTHECIN FROM IRINOTECAN
      Ken-ichi Fujita, Yuichi Ando, Masaru Narabayashi, Toshimichi Miya, Fumio Nagashima, Wataru Yamamoto, Keiji Kodama, Kazuhiro Araki, Hisashi Endo and Yasutsuna Sasaki
      Drug Metabolism and Disposition December 2005, 33 (12) 1785-1790; DOI: https://doi.org/10.1124/dmd.105.006205

  2. Nakajima, Miki

    1. CYP2A6 AND CYP2B6 ARE INVOLVED IN NORNICOTINE FORMATION FROM NICOTINE IN HUMANS: INTERINDIVIDUAL DIFFERENCES IN THESE CONTRIBUTIONS
      Hiroyuki Yamanaka, Miki Nakajima, Tatsuki Fukami, Haruko Sakai, Akiko Nakamura, Miki Katoh, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2005, 33 (12) 1811-1818; DOI: https://doi.org/10.1124/dmd.105.006254

  3. Nakamura, Akiko

    1. CYP2A6 AND CYP2B6 ARE INVOLVED IN NORNICOTINE FORMATION FROM NICOTINE IN HUMANS: INTERINDIVIDUAL DIFFERENCES IN THESE CONTRIBUTIONS
      Hiroyuki Yamanaka, Miki Nakajima, Tatsuki Fukami, Haruko Sakai, Akiko Nakamura, Miki Katoh, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2005, 33 (12) 1811-1818; DOI: https://doi.org/10.1124/dmd.105.006254

  4. Nakamura, Ryosuke

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

  5. Narabayashi, Masaru

    1. GEFITINIB (IRESSA) INHIBITS THE CYP3A4-MEDIATED FORMATION OF 7-ETHYL-10-(4-AMINO-1-PIPERIDINO)CARBONYLOXYCAMPTOTHECIN BUT ACTIVATES THAT OF 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO]CARBONYLOXYCAMPTOTHECIN FROM IRINOTECAN
      Ken-ichi Fujita, Yuichi Ando, Masaru Narabayashi, Toshimichi Miya, Fumio Nagashima, Wataru Yamamoto, Keiji Kodama, Kazuhiro Araki, Hisashi Endo and Yasutsuna Sasaki
      Drug Metabolism and Disposition December 2005, 33 (12) 1785-1790; DOI: https://doi.org/10.1124/dmd.105.006205

  6. Narimatsu, Shizuo

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

  7. Nelson, Sidney D.

    1. OXIDATION OF CAFFEINE BY CYP1A2: ISOTOPE EFFECTS AND METABOLIC SWITCHING
      Kelly A. Regal, Kent L. Kunze, Raimund M. Peter and Sidney D. Nelson
      Drug Metabolism and Disposition December 2005, 33 (12) 1837-1844; DOI: https://doi.org/10.1124/dmd.105.006031

O

  1. Ohbayashi, Masayuki

    1. FUNCTIONAL CHARACTERIZATION OF HUMAN MONOCARBOXYLATE TRANSPORTER 6 (SLC16A5)
      Yuichi Murakami, Noriko Kohyama, Yasuna Kobayashi, Masayuki Ohbayashi, Hisakazu Ohtani, Yasufumi Sawada and Toshinori Yamamoto
      Drug Metabolism and Disposition December 2005, 33 (12) 1845-1851; DOI: https://doi.org/10.1124/dmd.105.005264

  2. Ohtani, Hisakazu

    1. FUNCTIONAL CHARACTERIZATION OF HUMAN MONOCARBOXYLATE TRANSPORTER 6 (SLC16A5)
      Yuichi Murakami, Noriko Kohyama, Yasuna Kobayashi, Masayuki Ohbayashi, Hisakazu Ohtani, Yasufumi Sawada and Toshinori Yamamoto
      Drug Metabolism and Disposition December 2005, 33 (12) 1845-1851; DOI: https://doi.org/10.1124/dmd.105.005264

  3. Otagiri, Masaki

    1. HYDROLYSIS OF ANGIOTENSIN II RECEPTOR BLOCKER PRODRUG OLMESARTAN MEDOXOMIL BY HUMAN SERUM ALBUMIN AND IDENTIFICATION OF ITS CATALYTIC ACTIVE SITES
      Shen-Feng Ma, Makoto Anraku, Yasunori Iwao, Keishi Yamasaki, Ulrich Kragh-Hansen, Noriyuki Yamaotsu, Shuichi Hirono, Toshihiko Ikeda and Masaki Otagiri
      Drug Metabolism and Disposition December 2005, 33 (12) 1911-1919; DOI: https://doi.org/10.1124/dmd.105.006163

  4. Ozawa, Shogo

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

P

  1. Pearce, Robin E.

    1. PATHWAYS OF CARBAMAZEPINE BIOACTIVATION IN VITRO: II. THE ROLE OF HUMAN CYTOCHROME P450 ENZYMES IN THE FORMATION OF 2-HYDROXYIMINOSTILBENE
      Robin E. Pearce, Jack P. Uetrecht and J. Steven Leeder
      Drug Metabolism and Disposition December 2005, 33 (12) 1819-1826; DOI: https://doi.org/10.1124/dmd.105.004861

  2. Peter, Raimund M.

    1. OXIDATION OF CAFFEINE BY CYP1A2: ISOTOPE EFFECTS AND METABOLIC SWITCHING
      Kelly A. Regal, Kent L. Kunze, Raimund M. Peter and Sidney D. Nelson
      Drug Metabolism and Disposition December 2005, 33 (12) 1837-1844; DOI: https://doi.org/10.1124/dmd.105.006031

  3. Pool, William F.

    1. HUMAN IN VITRO GLUTATHIONYL AND PROTEIN ADDUCTS OF CARBAMAZEPINE-10,11-EPOXIDE, A STABLE AND PHARMACOLOGICALLY ACTIVE METABOLITE OF CARBAMAZEPINE
      Hai-Zhi Bu, Ping Kang, Alan J. Deese, Ping Zhao and William F. Pool
      Drug Metabolism and Disposition December 2005, 33 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.105.006866

R

  1. Rankin, Gary O.

    1. TRANSAMINATION IN THE METABOLISM OF THE NEPHROTOXICANT N-(3,5-DICHLOROPHENYL)SUCCINIMIDE IN RATS
      Donghui Cui, Gary O. Rankin and Peter J. Harvison
      Drug Metabolism and Disposition December 2005, 33 (12) 1765-1770; DOI: https://doi.org/10.1124/dmd.105.006593

  2. Rawden, Helen C.

    1. PREDICTION OF METABOLIC CLEARANCE USING CRYOPRESERVED HUMAN HEPATOCYTES: KINETIC CHARACTERISTICS FOR FIVE BENZODIAZEPINES
      David Hallifax, Helen C. Rawden, Nancy Hakooz and J. Brian Houston
      Drug Metabolism and Disposition December 2005, 33 (12) 1852-1858; DOI: https://doi.org/10.1124/dmd.105.005389

  3. Reed, James R.

    1. SPECIES DIFFERENCES IN THE ELIMINATION OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST HIGHLIGHTED BY OXIDATIVE METABOLISM OF ITS ACYL GLUCURONIDE
      Christopher J. Kochansky, Yuan-Qing Xia, Sui Wang, Brian Cato, Mellissa Creighton, Stella H. Vincent, Ronald B. Franklin and James R. Reed
      Drug Metabolism and Disposition December 2005, 33 (12) 1894-1904; DOI: https://doi.org/10.1124/dmd.105.004010

  4. Regal, Kelly A.

    1. OXIDATION OF CAFFEINE BY CYP1A2: ISOTOPE EFFECTS AND METABOLIC SWITCHING
      Kelly A. Regal, Kent L. Kunze, Raimund M. Peter and Sidney D. Nelson
      Drug Metabolism and Disposition December 2005, 33 (12) 1837-1844; DOI: https://doi.org/10.1124/dmd.105.006031

  5. Richter, K.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  6. Rougier, Nathalie

    1. SIMULTANEOUS MEASUREMENT OF 23 ISOFORMS FROM THE HUMAN CYTOCHROME P450 FAMILIES 1 TO 3 BY QUANTITATIVE REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION
      Igor Girault, Nathalie Rougier, Christophe Chesné, Rosette Lidereau, Philippe Beaune, Ivan Bieche and Isabelle de Waziers
      Drug Metabolism and Disposition December 2005, 33 (12) 1803-1810; DOI: https://doi.org/10.1124/dmd.105.005173

S

  1. Saito, Yoshiro

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

  2. Sakai, Haruko

    1. CYP2A6 AND CYP2B6 ARE INVOLVED IN NORNICOTINE FORMATION FROM NICOTINE IN HUMANS: INTERINDIVIDUAL DIFFERENCES IN THESE CONTRIBUTIONS
      Hiroyuki Yamanaka, Miki Nakajima, Tatsuki Fukami, Haruko Sakai, Akiko Nakamura, Miki Katoh, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2005, 33 (12) 1811-1818; DOI: https://doi.org/10.1124/dmd.105.006254

  3. Sasaki, Yasutsuna

    1. GEFITINIB (IRESSA) INHIBITS THE CYP3A4-MEDIATED FORMATION OF 7-ETHYL-10-(4-AMINO-1-PIPERIDINO)CARBONYLOXYCAMPTOTHECIN BUT ACTIVATES THAT OF 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO]CARBONYLOXYCAMPTOTHECIN FROM IRINOTECAN
      Ken-ichi Fujita, Yuichi Ando, Masaru Narabayashi, Toshimichi Miya, Fumio Nagashima, Wataru Yamamoto, Keiji Kodama, Kazuhiro Araki, Hisashi Endo and Yasutsuna Sasaki
      Drug Metabolism and Disposition December 2005, 33 (12) 1785-1790; DOI: https://doi.org/10.1124/dmd.105.006205

  4. Saulter, Janelle Y.

    1. UNUSUAL DEHYDROXYLATION OF ANTIMICROBIAL AMIDOXIME PRODRUGS BY CYTOCHROME b5 AND NADH CYTOCHROME b5 REDUCTASE
      Janelle Y. Saulter, Joseph R. Kurian, Lauren A. Trepanier, Richard R. Tidwell, Arlene S. Bridges, David W. Boykin, Chad E. Stephens, Mariappan Anbazhagan and James Edwin Hall
      Drug Metabolism and Disposition December 2005, 33 (12) 1886-1893; DOI: https://doi.org/10.1124/dmd.105.005017

  5. Sawada, Jun-ichi

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

  6. Sawada, Yasufumi

    1. FUNCTIONAL CHARACTERIZATION OF HUMAN MONOCARBOXYLATE TRANSPORTER 6 (SLC16A5)
      Yuichi Murakami, Noriko Kohyama, Yasuna Kobayashi, Masayuki Ohbayashi, Hisakazu Ohtani, Yasufumi Sawada and Toshinori Yamamoto
      Drug Metabolism and Disposition December 2005, 33 (12) 1845-1851; DOI: https://doi.org/10.1124/dmd.105.005264

  7. Schuetz, Erin G.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

  8. Shankar, Kartik

    1. SATURATION TOXICOKINETICS OF THIOACETAMIDE: ROLE IN INITIATION OF LIVER INJURY
      Jaya Chilakapati, Kartik Shankar, Midhun C. Korrapati, Ronald A. Hill and Harihara M. Mehendale
      Drug Metabolism and Disposition December 2005, 33 (12) 1877-1885; DOI: https://doi.org/10.1124/dmd.105.005520

  9. Sinclair, Jacqueline F.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

  10. Sinclair, Peter R.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

  11. Skott, A.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  12. Skrlin, Sara M.

    1. NICOTINE AND 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-BUTANONE METABOLISM BY CYTOCHROME P450 2B6
      Kari E. Dicke, Sara M. Skrlin and Sharon E. Murphy
      Drug Metabolism and Disposition December 2005, 33 (12) 1760-1764; DOI: https://doi.org/10.1124/dmd.105.006718

  13. Sörgel, F.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  14. Soyama, Akiko

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

  15. Stephens, Chad E.

    1. UNUSUAL DEHYDROXYLATION OF ANTIMICROBIAL AMIDOXIME PRODRUGS BY CYTOCHROME b5 AND NADH CYTOCHROME b5 REDUCTASE
      Janelle Y. Saulter, Joseph R. Kurian, Lauren A. Trepanier, Richard R. Tidwell, Arlene S. Bridges, David W. Boykin, Chad E. Stephens, Mariappan Anbazhagan and James Edwin Hall
      Drug Metabolism and Disposition December 2005, 33 (12) 1886-1893; DOI: https://doi.org/10.1124/dmd.105.005017

  16. Szakacs, Juliana G.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

T

  1. Takamiya, Masataka

    1. CYP2A6 AND CYP2B6 ARE INVOLVED IN NORNICOTINE FORMATION FROM NICOTINE IN HUMANS: INTERINDIVIDUAL DIFFERENCES IN THESE CONTRIBUTIONS
      Hiroyuki Yamanaka, Miki Nakajima, Tatsuki Fukami, Haruko Sakai, Akiko Nakamura, Miki Katoh, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2005, 33 (12) 1811-1818; DOI: https://doi.org/10.1124/dmd.105.006254

  2. Tam, Vincent H.

    1. DISPOSITION OF FLAVONOIDS VIA RECYCLING: COMPARISON OF INTESTINAL VERSUS HEPATIC DISPOSITION
      Jun Chen, Stephen Wang, Xiaobin Jia, Susan Bajimaya, Huimin Lin, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition December 2005, 33 (12) 1777-1784; DOI: https://doi.org/10.1124/dmd.105.003673

  3. Tamai, Ikumi

    1. INVOLVEMENT OF URIC ACID TRANSPORTER IN INCREASED RENAL CLEARANCE OF THE XANTHINE OXIDASE INHIBITOR OXYPURINOL INDUCED BY A URICOSURIC AGENT, BENZBROMARONE
      Takashi Iwanaga, Daisuke Kobayashi, Masamichi Hirayama, Tomoji Maeda and Ikumi Tamai
      Drug Metabolism and Disposition December 2005, 33 (12) 1791-1795; DOI: https://doi.org/10.1124/dmd.105.006056

  4. Tanaka-Kagawa, Toshiko

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

  5. Tang, Cuyue

    1. GLYCOSIDATION OF AN ENDOTHELIN ETA RECEPTOR ANTAGONIST AND DICLOFENAC IN HUMAN LIVER MICROSOMES: AGLYCONE-DEPENDENT UDP-SUGAR SELECTIVITY
      Cuyue Tang and Bennett Ma
      Drug Metabolism and Disposition December 2005, 33 (12) 1796-1802; DOI: https://doi.org/10.1124/dmd.105.005801

  6. Tidwell, Richard R.

    1. UNUSUAL DEHYDROXYLATION OF ANTIMICROBIAL AMIDOXIME PRODRUGS BY CYTOCHROME b5 AND NADH CYTOCHROME b5 REDUCTASE
      Janelle Y. Saulter, Joseph R. Kurian, Lauren A. Trepanier, Richard R. Tidwell, Arlene S. Bridges, David W. Boykin, Chad E. Stephens, Mariappan Anbazhagan and James Edwin Hall
      Drug Metabolism and Disposition December 2005, 33 (12) 1886-1893; DOI: https://doi.org/10.1124/dmd.105.005017

  7. Tomalik-Scharte, D.

    1. EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS
      D. Tomalik-Scharte, A. Jetter, M. Kinzig-Schippers, A. Skott, F. Sörgel, T. Klaassen, D. Kasel, S. Harlfinger, O. Doroshyenko, D. Frank, J. Kirchheiner, M. Bräter, K. Richter, T. Gramatté and U. Fuhr
      Drug Metabolism and Disposition December 2005, 33 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.105.005272

  8. Torres, Rhoda

    1. BIOACTIVATION OF 4-METHYLPHENOL (p-CRESOL) VIA CYTOCHROME P450-MEDIATED AROMATIC OXIDATION IN HUMAN LIVER MICROSOMES
      Zhengyin Yan, H. Marlon Zhong, Noureddine Maher, Rhoda Torres, Gregory C. Leo, Gary W. Caldwell and Norman Huebert
      Drug Metabolism and Disposition December 2005, 33 (12) 1867-1876; DOI: https://doi.org/10.1124/dmd.105.006387

  9. Trepanier, Lauren A.

    1. UNUSUAL DEHYDROXYLATION OF ANTIMICROBIAL AMIDOXIME PRODRUGS BY CYTOCHROME b5 AND NADH CYTOCHROME b5 REDUCTASE
      Janelle Y. Saulter, Joseph R. Kurian, Lauren A. Trepanier, Richard R. Tidwell, Arlene S. Bridges, David W. Boykin, Chad E. Stephens, Mariappan Anbazhagan and James Edwin Hall
      Drug Metabolism and Disposition December 2005, 33 (12) 1886-1893; DOI: https://doi.org/10.1124/dmd.105.005017

  10. Tsuneto, Yumi

    1. FUNCTIONAL ANALYSIS OF THREE CYP1A2 VARIANTS FOUND IN A JAPANESE POPULATION
      Yoshiro Saito, Nobumitsu Hanioka, Keiko Maekawa, Takashi Isobe, Yumi Tsuneto, Ryosuke Nakamura, Akiko Soyama, Shogo Ozawa, Toshiko Tanaka-Kagawa, Hideto Jinno, Shizuo Narimatsu and Jun-ichi Sawada
      Drug Metabolism and Disposition December 2005, 33 (12) 1905-1910; DOI: https://doi.org/10.1124/dmd.105.005819

U

  1. Uetrecht, Jack P.

    1. PATHWAYS OF CARBAMAZEPINE BIOACTIVATION IN VITRO: II. THE ROLE OF HUMAN CYTOCHROME P450 ENZYMES IN THE FORMATION OF 2-HYDROXYIMINOSTILBENE
      Robin E. Pearce, Jack P. Uetrecht and J. Steven Leeder
      Drug Metabolism and Disposition December 2005, 33 (12) 1819-1826; DOI: https://doi.org/10.1124/dmd.105.004861

V

  1. Vincent, Stella H.

    1. SPECIES DIFFERENCES IN THE ELIMINATION OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST HIGHLIGHTED BY OXIDATIVE METABOLISM OF ITS ACYL GLUCURONIDE
      Christopher J. Kochansky, Yuan-Qing Xia, Sui Wang, Brian Cato, Mellissa Creighton, Stella H. Vincent, Ronald B. Franklin and James R. Reed
      Drug Metabolism and Disposition December 2005, 33 (12) 1894-1904; DOI: https://doi.org/10.1124/dmd.105.004010

  2. von Moltke, Lisa L.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

W

  1. Walton-Strong, Brooke W.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

  2. Wang, Stephen

    1. DISPOSITION OF FLAVONOIDS VIA RECYCLING: COMPARISON OF INTESTINAL VERSUS HEPATIC DISPOSITION
      Jun Chen, Stephen Wang, Xiaobin Jia, Susan Bajimaya, Huimin Lin, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition December 2005, 33 (12) 1777-1784; DOI: https://doi.org/10.1124/dmd.105.003673

  3. Wang, Sui

    1. SPECIES DIFFERENCES IN THE ELIMINATION OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST HIGHLIGHTED BY OXIDATIVE METABOLISM OF ITS ACYL GLUCURONIDE
      Christopher J. Kochansky, Yuan-Qing Xia, Sui Wang, Brian Cato, Mellissa Creighton, Stella H. Vincent, Ronald B. Franklin and James R. Reed
      Drug Metabolism and Disposition December 2005, 33 (12) 1894-1904; DOI: https://doi.org/10.1124/dmd.105.004010

  4. Wolf, Kristina K.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

  5. Wood, Sheryl G.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

  6. Wrighton, Steven A.

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

X

  1. Xia, Yuan-Qing

    1. SPECIES DIFFERENCES IN THE ELIMINATION OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST HIGHLIGHTED BY OXIDATIVE METABOLISM OF ITS ACYL GLUCURONIDE
      Christopher J. Kochansky, Yuan-Qing Xia, Sui Wang, Brian Cato, Mellissa Creighton, Stella H. Vincent, Ronald B. Franklin and James R. Reed
      Drug Metabolism and Disposition December 2005, 33 (12) 1894-1904; DOI: https://doi.org/10.1124/dmd.105.004010

Y

  1. Yamamoto, Toshinori

    1. FUNCTIONAL CHARACTERIZATION OF HUMAN MONOCARBOXYLATE TRANSPORTER 6 (SLC16A5)
      Yuichi Murakami, Noriko Kohyama, Yasuna Kobayashi, Masayuki Ohbayashi, Hisakazu Ohtani, Yasufumi Sawada and Toshinori Yamamoto
      Drug Metabolism and Disposition December 2005, 33 (12) 1845-1851; DOI: https://doi.org/10.1124/dmd.105.005264

  2. Yamamoto, Wataru

    1. GEFITINIB (IRESSA) INHIBITS THE CYP3A4-MEDIATED FORMATION OF 7-ETHYL-10-(4-AMINO-1-PIPERIDINO)CARBONYLOXYCAMPTOTHECIN BUT ACTIVATES THAT OF 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO]CARBONYLOXYCAMPTOTHECIN FROM IRINOTECAN
      Ken-ichi Fujita, Yuichi Ando, Masaru Narabayashi, Toshimichi Miya, Fumio Nagashima, Wataru Yamamoto, Keiji Kodama, Kazuhiro Araki, Hisashi Endo and Yasutsuna Sasaki
      Drug Metabolism and Disposition December 2005, 33 (12) 1785-1790; DOI: https://doi.org/10.1124/dmd.105.006205

  3. Yamanaka, Hiroyuki

    1. CYP2A6 AND CYP2B6 ARE INVOLVED IN NORNICOTINE FORMATION FROM NICOTINE IN HUMANS: INTERINDIVIDUAL DIFFERENCES IN THESE CONTRIBUTIONS
      Hiroyuki Yamanaka, Miki Nakajima, Tatsuki Fukami, Haruko Sakai, Akiko Nakamura, Miki Katoh, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2005, 33 (12) 1811-1818; DOI: https://doi.org/10.1124/dmd.105.006254

  4. Yamaotsu, Noriyuki

    1. HYDROLYSIS OF ANGIOTENSIN II RECEPTOR BLOCKER PRODRUG OLMESARTAN MEDOXOMIL BY HUMAN SERUM ALBUMIN AND IDENTIFICATION OF ITS CATALYTIC ACTIVE SITES
      Shen-Feng Ma, Makoto Anraku, Yasunori Iwao, Keishi Yamasaki, Ulrich Kragh-Hansen, Noriyuki Yamaotsu, Shuichi Hirono, Toshihiko Ikeda and Masaki Otagiri
      Drug Metabolism and Disposition December 2005, 33 (12) 1911-1919; DOI: https://doi.org/10.1124/dmd.105.006163

  5. Yamasaki, Keishi

    1. HYDROLYSIS OF ANGIOTENSIN II RECEPTOR BLOCKER PRODRUG OLMESARTAN MEDOXOMIL BY HUMAN SERUM ALBUMIN AND IDENTIFICATION OF ITS CATALYTIC ACTIVE SITES
      Shen-Feng Ma, Makoto Anraku, Yasunori Iwao, Keishi Yamasaki, Ulrich Kragh-Hansen, Noriyuki Yamaotsu, Shuichi Hirono, Toshihiko Ikeda and Masaki Otagiri
      Drug Metabolism and Disposition December 2005, 33 (12) 1911-1919; DOI: https://doi.org/10.1124/dmd.105.006163

  6. Yan, Zhengyin

    1. BIOACTIVATION OF 4-METHYLPHENOL (p-CRESOL) VIA CYTOCHROME P450-MEDIATED AROMATIC OXIDATION IN HUMAN LIVER MICROSOMES
      Zhengyin Yan, H. Marlon Zhong, Noureddine Maher, Rhoda Torres, Gregory C. Leo, Gary W. Caldwell and Norman Huebert
      Drug Metabolism and Disposition December 2005, 33 (12) 1867-1876; DOI: https://doi.org/10.1124/dmd.105.006387

  7. Yasuda, Kazuto

    1. ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY
      Kristina K. Wolf, Sheryl G. Wood, Jane A. Hunt, Brooke W. Walton-Strong, Kazuto Yasuda, Lubin Lan, Su X. Duan, Qin Hao, Steven A. Wrighton, Elizabeth H. Jeffery, Ronald M. Evans, Juliana G. Szakacs, Lisa L. von Moltke, David J. Greenblatt, Michael H. Court, Erin G. Schuetz, Peter R. Sinclair and Jacqueline F. Sinclair
      Drug Metabolism and Disposition December 2005, 33 (12) 1827-1836; DOI: https://doi.org/10.1124/dmd.105.005256

  8. Yokoi, Tsuyoshi

    1. CYP2A6 AND CYP2B6 ARE INVOLVED IN NORNICOTINE FORMATION FROM NICOTINE IN HUMANS: INTERINDIVIDUAL DIFFERENCES IN THESE CONTRIBUTIONS
      Hiroyuki Yamanaka, Miki Nakajima, Tatsuki Fukami, Haruko Sakai, Akiko Nakamura, Miki Katoh, Masataka Takamiya, Yasuhiro Aoki and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2005, 33 (12) 1811-1818; DOI: https://doi.org/10.1124/dmd.105.006254

Z

  1. Zhao, Ping

    1. HUMAN IN VITRO GLUTATHIONYL AND PROTEIN ADDUCTS OF CARBAMAZEPINE-10,11-EPOXIDE, A STABLE AND PHARMACOLOGICALLY ACTIVE METABOLITE OF CARBAMAZEPINE
      Hai-Zhi Bu, Ping Kang, Alan J. Deese, Ping Zhao and William F. Pool
      Drug Metabolism and Disposition December 2005, 33 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.105.006866

  2. Zhong, H. Marlon

    1. BIOACTIVATION OF 4-METHYLPHENOL (p-CRESOL) VIA CYTOCHROME P450-MEDIATED AROMATIC OXIDATION IN HUMAN LIVER MICROSOMES
      Zhengyin Yan, H. Marlon Zhong, Noureddine Maher, Rhoda Torres, Gregory C. Leo, Gary W. Caldwell and Norman Huebert
      Drug Metabolism and Disposition December 2005, 33 (12) 1867-1876; DOI: https://doi.org/10.1124/dmd.105.006387
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