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Research ArticleArticle

PREDICTION OF METABOLIC CLEARANCE USING CRYOPRESERVED HUMAN HEPATOCYTES: KINETIC CHARACTERISTICS FOR FIVE BENZODIAZEPINES

David Hallifax, Helen C. Rawden, Nancy Hakooz and J. Brian Houston
Drug Metabolism and Disposition December 2005, 33 (12) 1852-1858; DOI: https://doi.org/10.1124/dmd.105.005389
David Hallifax
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Helen C. Rawden
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Nancy Hakooz
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J. Brian Houston
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Article Information

vol. 33 no. 12 1852-1858
DOI 
https://doi.org/10.1124/dmd.105.005389
PubMed 
16174807

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 28, 2005
  • Accepted September 16, 2005
  • Published online November 23, 2005.

Article Versions

  • Earlier version (September 20, 2005 - 11:33).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. David Hallifax,
  2. Helen C. Rawden,
  3. Nancy Hakooz and
  4. J. Brian Houston
  1. Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom
  1. Address correspondence to:
    Professor J. Brian Houston, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester M13 9PL, UK. E-mail: Brian.Houston{at}manchester.ac.uk
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Drug Metabolism and Disposition: 33 (12)
Drug Metabolism and Disposition
Vol. 33, Issue 12
1 Dec 2005
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Research ArticleArticle

PREDICTION OF METABOLIC CLEARANCE USING CRYOPRESERVED HUMAN HEPATOCYTES: KINETIC CHARACTERISTICS FOR FIVE BENZODIAZEPINES

David Hallifax, Helen C. Rawden, Nancy Hakooz and J. Brian Houston
Drug Metabolism and Disposition December 1, 2005, 33 (12) 1852-1858; DOI: https://doi.org/10.1124/dmd.105.005389

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Research ArticleArticle

PREDICTION OF METABOLIC CLEARANCE USING CRYOPRESERVED HUMAN HEPATOCYTES: KINETIC CHARACTERISTICS FOR FIVE BENZODIAZEPINES

David Hallifax, Helen C. Rawden, Nancy Hakooz and J. Brian Houston
Drug Metabolism and Disposition December 1, 2005, 33 (12) 1852-1858; DOI: https://doi.org/10.1124/dmd.105.005389
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