Table of Contents

Articles

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  MAPPING OF MULTIDRUG RESISTANCE GENE 1 AND MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN ISOFORM 1 TO 5 mRNA EXPRESSION ALONG THE HUMAN INTESTINAL TRACT

  Christian Zimmermann, Heike Gutmann, Petr Hruz, Jean-Pierre Gutzwiller, Christoph Beglinger and Juergen Drewe

  Drug Metabolism and Disposition February 2005, 33 (2) 219-224; DOI: https://doi.org/10.1124/dmd.104.001354
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  FUNCTIONAL ANALYSIS OF DOG MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2 (MRP2) IN COMPARISON WITH RAT MRP2

  Mizuki Ninomiya, Kousei Ito and Toshiharu Horie

  Drug Metabolism and Disposition February 2005, 33 (2) 225-232; DOI: https://doi.org/10.1124/dmd.104.002196
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  IMPACT OF TRANSCRIPTION FACTOR PROFILE AND CHROMATIN CONFORMATION ON HUMAN HEPATOCYTE CYP3A GENE EXPRESSION

  Anna Phillips, Steve R. Hood, G. Gordon Gibson and Nick J. Plant

  Drug Metabolism and Disposition February 2005, 33 (2) 233-242; DOI: https://doi.org/10.1124/dmd.104.001461
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  BIOACTIVATION OF THE NONTRICYCLIC ANTIDEPRESSANT NEFAZODONE TO A REACTIVE QUINONE-IMINE SPECIES IN HUMAN LIVER MICROSOMES AND RECOMBINANT CYTOCHROME P450 3A4

  Amit S. Kalgutkar, Alfin D. N. Vaz, Mary E. Lame, Kirk R. Henne, John Soglia, Sabrina X. Zhao, Yuri A. Abramov, Franco Lombardo, Claire Collin, Zachary S. Hendsch and Cornelis E. C. A. Hop

  Drug Metabolism and Disposition February 2005, 33 (2) 243-253; DOI: https://doi.org/10.1124/dmd.104.001735
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  FUNCTIONAL SIGNIFICANCE OF A NATURAL ALLELIC VARIANT OF HUMAN CARBONYL REDUCTASE 3 (CBR3)

  Sukhwinder S. Lakhman, Debashis Ghosh and Javier G. Blanco

  Drug Metabolism and Disposition February 2005, 33 (2) 254-257; DOI: https://doi.org/10.1124/dmd.104.002006
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  METABOLISM OF NICOTINE AND COTININE BY HUMAN CYTOCHROME P450 2A13

  Ziping Bao, Xiao-Yang He, Xinxin Ding, Saileta Prabhu and Jun-Yan Hong

  Drug Metabolism and Disposition February 2005, 33 (2) 258-261; DOI: https://doi.org/10.1124/dmd.104.002105
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  SERTRALINE IS METABOLIZED BY MULTIPLE CYTOCHROME P450 ENZYMES, MONOAMINE OXIDASES, AND GLUCURONYL TRANSFERASES IN HUMAN: AN IN VITRO STUDY

  R. Scott Obach, Loretta M. Cox and Larry M. Tremaine

  Drug Metabolism and Disposition February 2005, 33 (2) 262-270; DOI: https://doi.org/10.1124/dmd.104.002428
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  FORMATION AND PROTEIN BINDING OF THE ACYL GLUCURONIDE OF A LEUKOTRIENE B₄ ANTAGONIST (SB-209247): RELATION TO SPECIES DIFFERENCES IN HEPATOTOXICITY

  Jane R. Kenny, James L. Maggs, Justice N. A. Tettey, Andrew W. Harrell, Steven G. Parker, Stephen E. Clarke and B. Kevin Park

  Drug Metabolism and Disposition February 2005, 33 (2) 271-281; DOI: https://doi.org/10.1124/dmd.104.001677
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  ABSORPTION AND ELIMINATION OF FORMATE FOLLOWING ORAL ADMINISTRATION OF CALCIUM FORMATE IN FEMALE HUMAN SUBJECTS

  Robert P. Hanzlik, Stephen C. Fowler and Janis T. Eells

  Drug Metabolism and Disposition February 2005, 33 (2) 282-286; DOI: https://doi.org/10.1124/dmd.104.001289
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  MULTIPLE TRANSPORT SYSTEMS MEDIATE THE HEPATIC UPTAKE AND BILIARY EXCRETION OF THE METABOLICALLY STABLE OPIOID PEPTIDE [d-PENICILLAMINE^2,5]ENKEPHALIN

  Keith A. Hoffmaster, Maciej J. Zamek-Gliszczynski, Gary M. Pollack and Kim L. R. Brouwer

  Drug Metabolism and Disposition February 2005, 33 (2) 287-293; DOI: https://doi.org/10.1124/dmd.104.001420