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Drug Metabolism & Disposition

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Table of Contents

March 01, 2005; Volume 33,Issue 3

Articles

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    MALATHION BIOACTIVATION IN THE HUMAN LIVER: THE CONTRIBUTION OF DIFFERENT CYTOCHROME P450 ISOFORMS
    Franca M. Buratti, Alessandra D'Aniello, Maria Teresa Volpe, Annarita Meneguz and Emanuela Testai
    Drug Metabolism and Disposition March 2005, 33 (3) 295-302; DOI: https://doi.org/10.1124/dmd.104.001693
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    METABOLISM OF ALFENTANIL BY CYTOCHROME P4503A (CYP3A) ENZYMES
    Theresa Mariero Klees, Pamela Sheffels, Ola Dale and Evan D. Kharasch
    Drug Metabolism and Disposition March 2005, 33 (3) 303-311; DOI: https://doi.org/10.1124/dmd.104.002709
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    MECHANISMS OF ARSENITE-MEDIATED DECREASES IN BENZO[K]FLUORANTHENE-INDUCED HUMAN CYTOCHROME P4501A1 LEVELS IN HEPG2 CELLS
    Erin E. Bessette, Michael J. Fasco, Brian T. Pentecost and Laurence S. Kaminsky
    Drug Metabolism and Disposition March 2005, 33 (3) 312-320; DOI: https://doi.org/10.1124/dmd.104.002212
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    NEW 4-ARYL-1,4-DIHYDROPYRIDINES AND 4-ARYLPYRIDINES AS P-GLYCOPROTEIN INHIBITORS
    Xiao-fei Zhou, Linping Zhang, Elaine Tseng, Elizabeth Scott-Ramsay, Jerome J. Schentag, Robert A. Coburn and Marilyn E. Morris
    Drug Metabolism and Disposition March 2005, 33 (3) 321-328; DOI: https://doi.org/10.1124/dmd.104.002089
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    PHARMACOKINETICS OF TACROLIMUS AND MYCOPHENOLIC ACID ARE ALTERED, BUT RECOVER AT DIFFERENT TIMES DURING HEPATIC REGENERATION IN RATS
    Hui Tian, Junhai Ou, Stephen C. Strom and Raman Venkataramanan
    Drug Metabolism and Disposition March 2005, 33 (3) 329-335; DOI: https://doi.org/10.1124/dmd.104.002287
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    HUMAN CYTOCHROME P450 2S1: LACK OF ACTIVITY IN THE METABOLIC ACTIVATION OF SEVERAL CIGARETTE SMOKE CARCINOGENS AND IN THE METABOLISM OF NICOTINE
    Shou-Lin Wang, Xiao-Yang He and Jun-Yan Hong
    Drug Metabolism and Disposition March 2005, 33 (3) 336-340; DOI: https://doi.org/10.1124/dmd.104.002923
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    FLAVONOIDS CHRYSIN AND BENZOFLAVONE, POTENT BREAST CANCER RESISTANCE PROTEIN INHIBITORS, HAVE NO SIGNIFICANT EFFECT ON TOPOTECAN PHARMACOKINETICS IN RATS OR MDR1A/1B (–/–) MICE
    Shuzhong Zhang, Xiaodong Wang, Kazuko Sagawa and Marilyn E. Morris
    Drug Metabolism and Disposition March 2005, 33 (3) 341-348; DOI: https://doi.org/10.1124/dmd.104.002501
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    DEVELOPMENT AND VALIDATION OF A HIGH-THROUGHPUT RADIOMETRIC CYP3A4/5 INHIBITION ASSAY USING TRITIATED TESTOSTERONE
    Annalise Di Marco, Isabella Marcucci, Maria Verdirame, José Pérez, Manuel Sanchez, Fernando Peláez, Ashok Chaudhary and Ralph Laufer
    Drug Metabolism and Disposition March 2005, 33 (3) 349-358; DOI: https://doi.org/10.1124/dmd.104.002873
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    DEVELOPMENT AND VALIDATION OF A HIGH-THROUGHPUT RADIOMETRIC CYP2C9 INHIBITION ASSAY USING TRITIATED DICLOFENAC
    Annalise Di Marco, Isabella Marcucci, Ashok Chaudhary, Marina Taliani and Ralph Laufer
    Drug Metabolism and Disposition March 2005, 33 (3) 359-364; DOI: https://doi.org/10.1124/dmd.104.002915
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    tert-BUTYLHYDROQUINONE IS A NOVEL ARYL HYDROCARBON RECEPTOR LIGAND
    Negar Gharavi and Ayman O. S. El-Kadi
    Drug Metabolism and Disposition March 2005, 33 (3) 365-372; DOI: https://doi.org/10.1124/dmd.104.002253
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    COMPARATIVE METABOLISM OF POLYCHLORINATED BIPHENYLS AND TISSUE DISTRIBUTION OF PERSISTENT METABOLITES IN RATS, HAMSTERS, AND GUINEA PIGS
    Koichi Haraguchi, Nobuyuki Koga and Yoshihisa Kato
    Drug Metabolism and Disposition March 2005, 33 (3) 373-380; DOI: https://doi.org/10.1124/dmd.104.002444
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    RELATIONSHIPS AMONG PLASMA [2-13C]URACIL CONCENTRATIONS, BREATH 13CO2 EXPIRATION, AND DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) ACTIVITY IN THE LIVER IN NORMAL AND DPD-DEFICIENT DOGS
    Makoto Inada, Yukihiro Hirao, Toshihisa Koga, Minoru Itose, Jun-ichi Kunizaki, Takefumi Shimizu and Hitoshi Sato
    Drug Metabolism and Disposition March 2005, 33 (3) 381-387; DOI: https://doi.org/10.1124/dmd.104.001032
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    ASSESSMENT OF DRUG INTERACTIONS IN HEPATOBILIARY TRANSPORT USING RHODAMINE 123 IN SANDWICH-CULTURED RAT HEPATOCYTES
    Pieter P. Annaert and Kim L. R. Brouwer
    Drug Metabolism and Disposition March 2005, 33 (3) 388-394; DOI: https://doi.org/10.1124/dmd.104.001669
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    IN VITRO AND IN VIVO EVALUATION OF THE METABOLISM AND PHARMACOKINETICS OF SEBACOYL DINALBUPHINE
    Li-Heng Pao, Cheng-Huei Hsiong, Oliver Yoa-Pu Hu, Jhi-Jung Wang and Shung-Tai Ho
    Drug Metabolism and Disposition March 2005, 33 (3) 395-402; DOI: https://doi.org/10.1124/dmd.104.002451
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    REGIOSELECTIVE GLUCURONIDATION OF DENOPAMINE: MARKED SPECIES DIFFERENCES AND IDENTIFICATION OF HUMAN UDP-GLUCURONOSYLTRANSFERASE ISOFORM
    Hidefumi Kaji and Toshiyuki Kume
    Drug Metabolism and Disposition March 2005, 33 (3) 403-412; DOI: https://doi.org/10.1124/dmd.104.002667
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    SELECTIVE INHIBITION OF HUMAN CYTOCHROME P4502C8 BY MONTELUKAST
    Robert L. Walsky, R. Scott Obach, Emily A. Gaman, Jean-Paul R. Gleeson and William R. Proctor
    Drug Metabolism and Disposition March 2005, 33 (3) 413-418; DOI: https://doi.org/10.1124/dmd.104.002766
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    THE BINDING OF DRUGS TO HEPATOCYTES AND ITS RELATIONSHIP TO PHYSICOCHEMICAL PROPERTIES
    Rupert P. Austin, Patrick Barton, Sarfraz Mohmed and Robert J. Riley
    Drug Metabolism and Disposition March 2005, 33 (3) 419-425; DOI: https://doi.org/10.1124/dmd.104.002436
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    DO MEN AND WOMEN DIFFER IN PROXIMAL SMALL INTESTINAL CYP3A OR P-GLYCOPROTEIN EXPRESSION?
    Mary F. Paine, Shana S. Ludington, Mei-Ling Chen, Paul W. Stewart, Shiew-Mei Huang and Paul B. Watkins
    Drug Metabolism and Disposition March 2005, 33 (3) 426-433; DOI: https://doi.org/10.1124/dmd.104.002469
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    ROLE OF ORGANIC ANION TRANSPORTER OATP1B1 (OATP-C) IN HEPATIC UPTAKE OF IRINOTECAN AND ITS ACTIVE METABOLITE, 7-ETHYL-10-HYDROXYCAMPTOTHECIN: IN VITRO EVIDENCE AND EFFECT OF SINGLE NUCLEOTIDE POLYMORPHISMS
    Takashi Nozawa, Hironobu Minami, Shigeki Sugiura, Akira Tsuji and Ikumi Tamai
    Drug Metabolism and Disposition March 2005, 33 (3) 434-439; DOI: https://doi.org/10.1124/dmd.104.001909
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    SATURABLE DISTRIBUTION OF TACRINE INTO THE STRIATAL EXTRACELLULAR FLUID OF THE RAT: EVIDENCE OF INVOLVEMENT OF MULTIPLE ORGANIC CATION TRANSPORTERS IN THE TRANSPORT
    Jong-Hyuk Sung, Kyung-Ha Yu, Jin-Sun Park, Takashi Tsuruo, Dae-Duk Kim, Chang-Koo Shim and Suk-Jae Chung
    Drug Metabolism and Disposition March 2005, 33 (3) 440-448; DOI: https://doi.org/10.1124/dmd.104.002220
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    THE CYP2E1-HUMANIZED TRANSGENIC MOUSE: ROLE OF CYP2E1 IN ACETAMINOPHEN HEPATOTOXICITY
    Connie Cheung, Ai-Ming Yu, Jerrold M. Ward, Kristopher W. Krausz, Taro E. Akiyama, Lionel Feigenbaum and Frank J. Gonzalez
    Drug Metabolism and Disposition March 2005, 33 (3) 449-457; DOI: https://doi.org/10.1124/dmd.104.002402
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    RACIAL VARIABILITY IN HAPLOTYPE FREQUENCIES OF UGT1A1 AND GLUCURONIDATION ACTIVITY OF A NOVEL SINGLE NUCLEOTIDE POLYMORPHISM 686C> T (P229L) FOUND IN AN AFRICAN-AMERICAN
    Nahoko Kaniwa, Kouichi Kurose, Hideto Jinno, Toshiko Tanaka-Kagawa, Yoshiro Saito, Mayumi Saeki, Jun-ichi Sawada, Masahiro Tohkin and Ryuichi Hasegawa
    Drug Metabolism and Disposition March 2005, 33 (3) 458-465; DOI: https://doi.org/10.1124/dmd.104.001800
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    CYTOCHROME P450-MEDIATED OXIDATION OF GLUCURONIDE DERIVATIVES: EXAMPLE OF ESTRADIOL-17β-GLUCURONIDE OXIDATION TO 2-HYDROXY-ESTRADIOL-17β-GLUCURONIDE BY CYP 2C8
    M. Delaforge, A. Pruvost, L. Perrin and F. André
    Drug Metabolism and Disposition March 2005, 33 (3) 466-473; DOI: https://doi.org/10.1124/dmd.104.002097

Accelerated Communication

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    A NOVEL METHOD FOR VISUALIZING NUCLEAR HORMONE RECEPTOR NETWORKS RELEVANT TO DRUG METABOLISM
    Sean Ekins, Eugene Kirillov, Eugene A. Rakhmatulin and Tatiana Nikolskaya
    Drug Metabolism and Disposition March 2005, 33 (3) 474-481; DOI: https://doi.org/10.1124/dmd.104.002717
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Drug Metabolism and Disposition: 33 (3)
Drug Metabolism and Disposition
Vol. 33, Issue 3
1 Mar 2005
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