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Research ArticleArticle

THE CYP2E1-HUMANIZED TRANSGENIC MOUSE: ROLE OF CYP2E1 IN ACETAMINOPHEN HEPATOTOXICITY

Connie Cheung, Ai-Ming Yu, Jerrold M. Ward, Kristopher W. Krausz, Taro E. Akiyama, Lionel Feigenbaum and Frank J. Gonzalez
Drug Metabolism and Disposition March 2005, 33 (3) 449-457; DOI: https://doi.org/10.1124/dmd.104.002402
Connie Cheung
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Ai-Ming Yu
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Jerrold M. Ward
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Kristopher W. Krausz
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Taro E. Akiyama
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Lionel Feigenbaum
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Frank J. Gonzalez
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Article Information

vol. 33 no. 3 449-457
DOI 
https://doi.org/10.1124/dmd.104.002402
PubMed 
15576447

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 16, 2004
  • Accepted November 30, 2004
  • Published online February 14, 2005.

Article Versions

  • Earlier version (December 2, 2004 - 06:48).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Connie Cheung,
  2. Ai-Ming Yu1,
  3. Jerrold M. Ward,
  4. Kristopher W. Krausz,
  5. Taro E. Akiyama2,
  6. Lionel Feigenbaum and
  7. Frank J. Gonzalez
  1. Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (C.C., A-M.Y., K.W.K., T.E.A., F.J.G.); Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, and SoBran, Inc., Bethesda, Maryland (J.M.W.); and Laboratory Animal Science Program, Science Applications International Corporation, National Cancer Institute, Frederick, Maryland (L.F.)
  1. Address correspondence to:
    Dr. F. J. Gonzalez, Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Building 37, Room 3106, 9000 Rockville Pike, Bethesda, MD. E-mail: fjgonz{at}helix.nih.gov
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Drug Metabolism and Disposition: 33 (3)
Drug Metabolism and Disposition
Vol. 33, Issue 3
1 Mar 2005
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Research ArticleArticle

THE CYP2E1-HUMANIZED TRANSGENIC MOUSE: ROLE OF CYP2E1 IN ACETAMINOPHEN HEPATOTOXICITY

Connie Cheung, Ai-Ming Yu, Jerrold M. Ward, Kristopher W. Krausz, Taro E. Akiyama, Lionel Feigenbaum and Frank J. Gonzalez
Drug Metabolism and Disposition March 1, 2005, 33 (3) 449-457; DOI: https://doi.org/10.1124/dmd.104.002402

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Research ArticleArticle

THE CYP2E1-HUMANIZED TRANSGENIC MOUSE: ROLE OF CYP2E1 IN ACETAMINOPHEN HEPATOTOXICITY

Connie Cheung, Ai-Ming Yu, Jerrold M. Ward, Kristopher W. Krausz, Taro E. Akiyama, Lionel Feigenbaum and Frank J. Gonzalez
Drug Metabolism and Disposition March 1, 2005, 33 (3) 449-457; DOI: https://doi.org/10.1124/dmd.104.002402
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