Drug Metabolism and Disposition: 33 (4)

April 01, 2005; Volume 33,Issue 4

Commentary

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Commentary: David Kupfer, Ph.D., 1925–2004
John Schenkman

Drug Metabolism and Disposition April 2005, 33 (4) 483; DOI: https://doi.org/10.1124/dmd.105.003582

Short Communication

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IDENTIFICATION OF A NOVEL GLUTATHIONE ADDUCT OF DICLOFENAC, 4′-HYDROXY-2′-GLUTATHION-DESCHLORO-DICLOFENAC, UPON INCUBATION WITH HUMAN LIVER MICROSOMES
Li J. Yu, Yue Chen, Michael P. Deninno, Thomas N. O'Connell and Cornelis E. C. A. Hop

Drug Metabolism and Disposition April 2005, 33 (4) 484-488; DOI: https://doi.org/10.1124/dmd.104.002840

Articles

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METABOLISM OF MELATONIN BY HUMAN CYTOCHROMES P450
Xiaochao Ma, Jeffrey R. Idle, Kristopher W. Krausz and Frank J. Gonzalez

Drug Metabolism and Disposition April 2005, 33 (4) 489-494; DOI: https://doi.org/10.1124/dmd.104.002410
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TRANSPORT OF THE DOPAMINE D₂ AGONIST PRAMIPEXOLE BY RAT ORGANIC CATION TRANSPORTERS OCT1 AND OCT2 IN KIDNEY
Naoki Ishiguro, Asami Saito, Kazutoshi Yokoyama, Makoto Morikawa, Takashi Igarashi and Ikumi Tamai

Drug Metabolism and Disposition April 2005, 33 (4) 495-499; DOI: https://doi.org/10.1124/dmd.104.002519
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CYTOCHROME P450 3A-MEDIATED METABOLISM OF BUSPIRONE IN HUMAN LIVER MICROSOMES
Mingshe Zhu, Weiping Zhao, Humberto Jimenez, Donglu Zhang, Suresh Yeola, Renke Dai, Nimish Vachharajani and James Mitroka

Drug Metabolism and Disposition April 2005, 33 (4) 500-507; DOI: https://doi.org/10.1124/dmd.104.000836
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IN VITRO METABOLISM OF DIARYLPYRAZOLES, A NOVEL GROUP OF CANNABINOID RECEPTOR LIGANDS
Qiang Zhang, Peng Ma, Weiqun Wang, Richard B. Cole and Guangdi Wang

Drug Metabolism and Disposition April 2005, 33 (4) 508-517; DOI: https://doi.org/10.1124/dmd.104.001974
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CITRUS JUICES INHIBIT THE FUNCTION OF HUMAN ORGANIC ANION-TRANSPORTING POLYPEPTIDE OATP-B
Hiroki Satoh, Fumiaki Yamashita, Masayuki Tsujimoto, Hideyasu Murakami, Noriko Koyabu, Hisakazu Ohtani and Yasufumi Sawada

Drug Metabolism and Disposition April 2005, 33 (4) 518-523; DOI: https://doi.org/10.1124/dmd.104.002337
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EXPRESSION AND FUNCTION OF ABCB1 AND ABCG2 IN HUMAN PLACENTAL TISSUE
Dhanashri Kolwankar, Douglas D. Glover, Joseph A. Ware and Timothy S. Tracy

Drug Metabolism and Disposition April 2005, 33 (4) 524-529; DOI: https://doi.org/10.1124/dmd.104.002261
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STRUCTURAL AND ENZYMATIC PARAMETERS THAT DETERMINE ALKYL DEHYDROGENATION/HYDROXYLATION OF CAPSAICINOIDS BY CYTOCHROME P450 ENZYMES
Christopher A. Reilly and Garold S. Yost

Drug Metabolism and Disposition April 2005, 33 (4) 530-536; DOI: https://doi.org/10.1124/dmd.104.001214
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DIFFERENTIAL INTERACTION OF 3-HYDROXY-3-METHYLGLUTARYL-COA REDUCTASE INHIBITORS WITH ABCB1, ABCC2, AND OATP1B1
Cuiping Chen, Rouchelle J. Mireles, Scott D. Campbell, Jian Lin, Jessica B. Mills, Jinghai J. Xu and Teresa A. Smolarek

Drug Metabolism and Disposition April 2005, 33 (4) 537-546; DOI: https://doi.org/10.1124/dmd.104.002477
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FUNCTIONAL INDUCTION AND DE-INDUCTION OF P-GLYCOPROTEIN BY ST. JOHN'S WORT AND ITS INGREDIENTS IN A HUMAN COLON ADENOCARCINOMA CELL LINE
Run Tian, Noriko Koyabu, Satoshi Morimoto, Yukihiro Shoyama, Hisakazu Ohtani and Yasufumi Sawada

Drug Metabolism and Disposition April 2005, 33 (4) 547-554; DOI: https://doi.org/10.1124/dmd.104.002485
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ISOLATION AND IDENTIFICATION OF SEVEN GLUCURONIDE CONJUGATES OF ANDROGRAPHOLIDE IN HUMAN URINE
Liang Cui, Feng Qiu and Xinsheng Yao

Drug Metabolism and Disposition April 2005, 33 (4) 555-562; DOI: https://doi.org/10.1124/dmd.104.001958
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HUMAN LIVER S9 FRACTIONS: METABOLISM OF DEHYDROEPIANDROSTERONE, EPIANDROSTERONE, AND RELATED 7-HYDROXYLATED DERIVATIVES
Sonia Chalbot and Robert Morfin

Drug Metabolism and Disposition April 2005, 33 (4) 563-569; DOI: https://doi.org/10.1124/dmd.104.003004
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CHARACTERIZATION AND PARTIAL PURIFICATION OF THE RAT AND HUMAN ENZYME SYSTEMS ACTIVE IN THE REDUCTION OF N-HYDROXYMELAGATRAN AND BENZAMIDOXIME
Susanne Andersson, Yvonne Hofmann, Åsa Nordling, Xue-qing Li, Sabina Nivelius, Tommy B. Andersson, Magnus Ingelman-Sundberg and Inger Johansson

Drug Metabolism and Disposition April 2005, 33 (4) 570-578; DOI: https://doi.org/10.1124/dmd.104.002972
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EFFECT OF EARLY PHASE ADJUVANT ARTHRITIS ON HEPATIC P450 ENZYMES AND PHARMACOKINETICS OF VERAPAMIL: AN ALTERNATIVE APPROACH TO THE USE OF AN ANIMAL MODEL OF INFLAMMATION FOR PHARMACOKINETIC STUDIES
Spencer Ling and Fakhreddin Jamali

Drug Metabolism and Disposition April 2005, 33 (4) 579-586; DOI: https://doi.org/10.1124/dmd.104.002360
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SPECIES DIFFERENCES IN THE DISPOSITION OF THE CCR5 ANTAGONIST, UK-427,857, A NEW POTENTIAL TREATMENT FOR HIV
Don K. Walker, Samantha Abel, Pierre Comby, Gary J. Muirhead, Angus N. R. Nedderman and Dennis A. Smith

Drug Metabolism and Disposition April 2005, 33 (4) 587-595; DOI: https://doi.org/10.1124/dmd.104.002626
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BUCOLOME, A POTENT BINDING INHIBITOR FOR FUROSEMIDE, ALTERS THE PHARMACOKINETICS AND DIURETIC EFFECT OF FUROSEMIDE: POTENTIAL FOR USE OF BUCOLOME TO RESTORE DIURETIC RESPONSE IN NEPHROTIC SYNDROME
Norito Takamura, Toru Maruyama, Etsuo Chosa, Keiichi Kawai, Yasuhiro Tsutsumi, Yukie Uryu, Keishi Yamasaki, Tsuneo Deguchi and Masaki Otagiri

Drug Metabolism and Disposition April 2005, 33 (4) 596-602; DOI: https://doi.org/10.1124/dmd.104.002782

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