Drug Metabolism and Disposition: 33 (4)

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14-deoxy-12-hydroxy-andrographolide-19-O--D-glucuronide(A), metabolite M-5, 14 deoxy-12(13)-en-andrographolide-19-O--D-glucuronide (B), metabolite M-6, 14 deoxyandrographolide-19-O--D-glucuronide (C), and metabolite M-7, 3-oxoandrogarapholide-19-O--D-glucuronide (D). See the article by Cui et al. on page 555 of this issue.

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Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUC_I/AUC) RATIOS
THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model

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