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Research ArticleArticle

CYTOCHROME P450 3A-MEDIATED METABOLISM OF BUSPIRONE IN HUMAN LIVER MICROSOMES

Mingshe Zhu, Weiping Zhao, Humberto Jimenez, Donglu Zhang, Suresh Yeola, Renke Dai, Nimish Vachharajani and James Mitroka
Drug Metabolism and Disposition April 2005, 33 (4) 500-507; DOI: https://doi.org/10.1124/dmd.104.000836
Mingshe Zhu
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Weiping Zhao
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Humberto Jimenez
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Donglu Zhang
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Suresh Yeola
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Renke Dai
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Nimish Vachharajani
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James Mitroka
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Article Information

vol. 33 no. 4 500-507
DOI 
https://doi.org/10.1124/dmd.104.000836
PubMed 
15640381

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 3, 2004
  • Accepted January 3, 2005
  • Published online March 21, 2005.

Article Versions

  • Earlier version (January 7, 2005 - 10:53).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Mingshe Zhu,
  2. Weiping Zhao,
  3. Humberto Jimenez,
  4. Donglu Zhang,
  5. Suresh Yeola,
  6. Renke Dai,
  7. Nimish Vachharajani and
  8. James Mitroka
  1. Pharmaceutical Candidate Optimization (M.Z., W.Z., H.J., D.Z., S.Y., R.D., J.M.), and Clinical Discovery (N.V.), Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey
  1. Address correspondence to:
    Dr. Mingshe Zhu, Bristol-Myers Squibb, F13-01, PCO, Biotransformation Dept., Princeton, NJ 08543-4000. E-mail: mingshe.zhu{at}bms.com
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Drug Metabolism and Disposition: 33 (4)
Drug Metabolism and Disposition
Vol. 33, Issue 4
1 Apr 2005
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Research ArticleArticle

CYTOCHROME P450 3A-MEDIATED METABOLISM OF BUSPIRONE IN HUMAN LIVER MICROSOMES

Mingshe Zhu, Weiping Zhao, Humberto Jimenez, Donglu Zhang, Suresh Yeola, Renke Dai, Nimish Vachharajani and James Mitroka
Drug Metabolism and Disposition April 1, 2005, 33 (4) 500-507; DOI: https://doi.org/10.1124/dmd.104.000836

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Research ArticleArticle

CYTOCHROME P450 3A-MEDIATED METABOLISM OF BUSPIRONE IN HUMAN LIVER MICROSOMES

Mingshe Zhu, Weiping Zhao, Humberto Jimenez, Donglu Zhang, Suresh Yeola, Renke Dai, Nimish Vachharajani and James Mitroka
Drug Metabolism and Disposition April 1, 2005, 33 (4) 500-507; DOI: https://doi.org/10.1124/dmd.104.000836
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