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Index by author

June 01, 2005; Volume 33,Issue 6

A

  1. Abe, Daisuke

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

  2. Anzenbacher, Pavel

    1. MINIPIG CYTOCHROME P450 2E1: COMPARISON WITH HUMAN ENZYME
      Jana Baranová, Eva Anzenbacherová, Pavel Anzenbacher and Pavel Souček
      Drug Metabolism and Disposition June 2005, 33 (6) 862-865; DOI: https://doi.org/10.1124/dmd.104.003392

  3. Anzenbacherová, Eva

    1. MINIPIG CYTOCHROME P450 2E1: COMPARISON WITH HUMAN ENZYME
      Jana Baranová, Eva Anzenbacherová, Pavel Anzenbacher and Pavel Souček
      Drug Metabolism and Disposition June 2005, 33 (6) 862-865; DOI: https://doi.org/10.1124/dmd.104.003392

  4. Arthaud, Larry

    1. THE DISTRIBUTION, METABOLISM, AND ELIMINATION OF CLOFARABINE IN RATS
      Peter L. Bonate, Larry Arthaud, John Stuhler, Phyllis Yerino, Randall J. Press and James Q. Rose
      Drug Metabolism and Disposition June 2005, 33 (6) 739-748; DOI: https://doi.org/10.1124/dmd.104.002592

  5. Attaccalite, Silvia

    1. DETERMINATION OF DRUG GLUCURONIDATION AND UDP-GLUCURONOSYLTRANSFERASE SELECTIVITY USING A 96-WELL RADIOMETRIC ASSAY
      Annalise Di Marco, Michelle D'Antoni, Silvia Attaccalite, Pietro Carotenuto and Ralph Laufer
      Drug Metabolism and Disposition June 2005, 33 (6) 812-819; DOI: https://doi.org/10.1124/dmd.105.004333

B

  1. Baranová, Jana

    1. MINIPIG CYTOCHROME P450 2E1: COMPARISON WITH HUMAN ENZYME
      Jana Baranová, Eva Anzenbacherová, Pavel Anzenbacher and Pavel Souček
      Drug Metabolism and Disposition June 2005, 33 (6) 862-865; DOI: https://doi.org/10.1124/dmd.104.003392

  2. Baronas, Elizabeth

    1. HUMAN METABOLISM OF THE PROTEASOME INHIBITOR BORTEZOMIB: IDENTIFICATION OF CIRCULATING METABOLITES
      Teresa Pekol, J. Scott Daniels, Jason Labutti, Ian Parsons, Darrell Nix, Elizabeth Baronas, Frank Hsieh, Liang-Shang Gan and Gerald Miwa
      Drug Metabolism and Disposition June 2005, 33 (6) 771-777; DOI: https://doi.org/10.1124/dmd.104.002956

  3. Baughman, T. M.

    1. METABOLIC ACTIVATION OF PIOGLITAZONE IDENTIFIED FROM RAT AND HUMAN LIVER MICROSOMES AND FRESHLY ISOLATED HEPATOCYTES
      T. M. Baughman, R. A. Graham, K. Wells-Knecht, I. S. Silver, L. O. Tyler, M. Wells-Knecht and Z. Zhao
      Drug Metabolism and Disposition June 2005, 33 (6) 733-738; DOI: https://doi.org/10.1124/dmd.104.002683

  4. Bonate, Peter L.

    1. THE DISTRIBUTION, METABOLISM, AND ELIMINATION OF CLOFARABINE IN RATS
      Peter L. Bonate, Larry Arthaud, John Stuhler, Phyllis Yerino, Randall J. Press and James Q. Rose
      Drug Metabolism and Disposition June 2005, 33 (6) 739-748; DOI: https://doi.org/10.1124/dmd.104.002592

  5. Bumpus, Namandjé N.

    1. THE NATURALLY OCCURRING CYTOCHROME P450 (P450) 2B6 K262R MUTANT OF P450 2B6 EXHIBITS ALTERATIONS IN SUBSTRATE METABOLISM AND INACTIVATION
      Namandjé N. Bumpus, Chitra Sridar, Ute M. Kent and Paul F. Hollenberg
      Drug Metabolism and Disposition June 2005, 33 (6) 795-802; DOI: https://doi.org/10.1124/dmd.105.003749

  6. Burczynski, Frank J.

    1. METABOLISM OF THE CARDIOPROTECTIVE DRUG DEXRAZOXANE AND ONE OF ITS METABOLITES BY ISOLATED RAT MYOCYTES, HEPATOCYTES, AND BLOOD
      Patricia E. Schroeder, Gu-Qi Wang, Frank J. Burczynski and Brian B. Hasinoff
      Drug Metabolism and Disposition June 2005, 33 (6) 719-725; DOI: https://doi.org/10.1124/dmd.104.003186

C

  1. Caldwell, Gary W.

    1. DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES
      Zhengyin Yan, Jian Li, Norman Huebert, Gary W. Caldwell, Yanming Du and Hua Zhong
      Drug Metabolism and Disposition June 2005, 33 (6) 706-713; DOI: https://doi.org/10.1124/dmd.104.003095

  2. Carotenuto, Pietro

    1. DETERMINATION OF DRUG GLUCURONIDATION AND UDP-GLUCURONOSYLTRANSFERASE SELECTIVITY USING A 96-WELL RADIOMETRIC ASSAY
      Annalise Di Marco, Michelle D'Antoni, Silvia Attaccalite, Pietro Carotenuto and Ralph Laufer
      Drug Metabolism and Disposition June 2005, 33 (6) 812-819; DOI: https://doi.org/10.1124/dmd.105.004333

  3. Chen, Xiaoyan

    1. ROLE OF CYP2C9 AND ITS VARIANTS (CYP2C9*3 AND CYP2C9*13) IN THE METABOLISM OF LORNOXICAM IN HUMANS
      Yingjie Guo, Yifan Zhang, Ying Wang, Xiaoyan Chen, Dayong Si, Dafang Zhong, J. Paul Fawcett and Hui Zhou
      Drug Metabolism and Disposition June 2005, 33 (6) 749-753; DOI: https://doi.org/10.1124/dmd.105.003616

  4. Choi, Man Ho

    1. CHARACTERIZATION OF TESTOSTERONE 11β-HYDROXYLATION CATALYZED BY HUMAN LIVER MICROSOMAL CYTOCHROMES P450
      Man Ho Choi, Paul L. Skipper, John S. Wishnok and Steven R. Tannenbaum
      Drug Metabolism and Disposition June 2005, 33 (6) 714-718; DOI: https://doi.org/10.1124/dmd.104.003327

D

  1. D'Antoni, Michelle

    1. DETERMINATION OF DRUG GLUCURONIDATION AND UDP-GLUCURONOSYLTRANSFERASE SELECTIVITY USING A 96-WELL RADIOMETRIC ASSAY
      Annalise Di Marco, Michelle D'Antoni, Silvia Attaccalite, Pietro Carotenuto and Ralph Laufer
      Drug Metabolism and Disposition June 2005, 33 (6) 812-819; DOI: https://doi.org/10.1124/dmd.105.004333

  2. Daniels, J. Scott

    1. HUMAN METABOLISM OF THE PROTEASOME INHIBITOR BORTEZOMIB: IDENTIFICATION OF CIRCULATING METABOLITES
      Teresa Pekol, J. Scott Daniels, Jason Labutti, Ian Parsons, Darrell Nix, Elizabeth Baronas, Frank Hsieh, Liang-Shang Gan and Gerald Miwa
      Drug Metabolism and Disposition June 2005, 33 (6) 771-777; DOI: https://doi.org/10.1124/dmd.104.002956

  3. Di Marco, Annalise

    1. DETERMINATION OF DRUG GLUCURONIDATION AND UDP-GLUCURONOSYLTRANSFERASE SELECTIVITY USING A 96-WELL RADIOMETRIC ASSAY
      Annalise Di Marco, Michelle D'Antoni, Silvia Attaccalite, Pietro Carotenuto and Ralph Laufer
      Drug Metabolism and Disposition June 2005, 33 (6) 812-819; DOI: https://doi.org/10.1124/dmd.105.004333

  4. Du, Yanming

    1. DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES
      Zhengyin Yan, Jian Li, Norman Huebert, Gary W. Caldwell, Yanming Du and Hua Zhong
      Drug Metabolism and Disposition June 2005, 33 (6) 706-713; DOI: https://doi.org/10.1124/dmd.104.003095

  5. Duan, Su X.

    1. ATAZANAVIR: EFFECTS ON P-GLYCOPROTEIN TRANSPORT AND CYP3A METABOLISM IN VITRO
      Elke S. Perloff, Su X. Duan, Paul R. Skolnik, David J. Greenblatt and Lisa L. von Moltke
      Drug Metabolism and Disposition June 2005, 33 (6) 764-770; DOI: https://doi.org/10.1124/dmd.104.002931

F

  1. Fawcett, J. Paul

    1. ROLE OF CYP2C9 AND ITS VARIANTS (CYP2C9*3 AND CYP2C9*13) IN THE METABOLISM OF LORNOXICAM IN HUMANS
      Yingjie Guo, Yifan Zhang, Ying Wang, Xiaoyan Chen, Dayong Si, Dafang Zhong, J. Paul Fawcett and Hui Zhou
      Drug Metabolism and Disposition June 2005, 33 (6) 749-753; DOI: https://doi.org/10.1124/dmd.105.003616

  2. Fujishima, Toshie

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

G

  1. Gan, Liang-Shang

    1. HUMAN METABOLISM OF THE PROTEASOME INHIBITOR BORTEZOMIB: IDENTIFICATION OF CIRCULATING METABOLITES
      Teresa Pekol, J. Scott Daniels, Jason Labutti, Ian Parsons, Darrell Nix, Elizabeth Baronas, Frank Hsieh, Liang-Shang Gan and Gerald Miwa
      Drug Metabolism and Disposition June 2005, 33 (6) 771-777; DOI: https://doi.org/10.1124/dmd.104.002956

  2. Graham, R. A.

    1. METABOLIC ACTIVATION OF PIOGLITAZONE IDENTIFIED FROM RAT AND HUMAN LIVER MICROSOMES AND FRESHLY ISOLATED HEPATOCYTES
      T. M. Baughman, R. A. Graham, K. Wells-Knecht, I. S. Silver, L. O. Tyler, M. Wells-Knecht and Z. Zhao
      Drug Metabolism and Disposition June 2005, 33 (6) 733-738; DOI: https://doi.org/10.1124/dmd.104.002683

  3. Greenblatt, David J.

    1. ATAZANAVIR: EFFECTS ON P-GLYCOPROTEIN TRANSPORT AND CYP3A METABOLISM IN VITRO
      Elke S. Perloff, Su X. Duan, Paul R. Skolnik, David J. Greenblatt and Lisa L. von Moltke
      Drug Metabolism and Disposition June 2005, 33 (6) 764-770; DOI: https://doi.org/10.1124/dmd.104.002931

  4. Gunnarsson, Per Olov

    1. CYTOCHROME P450 3A4 IS THE MAJOR ENZYME RESPONSIBLE FOR THE METABOLISM OF LAQUINIMOD, A NOVEL IMMUNOMODULATOR
      Helén Tuvesson, Ingrid Hallin, Robert Persson, Birgitta Sparre, Per Olov Gunnarsson and Janeric Seidegård
      Drug Metabolism and Disposition June 2005, 33 (6) 866-872; DOI: https://doi.org/10.1124/dmd.104.002238

  5. Guo, Yingjie

    1. ROLE OF CYP2C9 AND ITS VARIANTS (CYP2C9*3 AND CYP2C9*13) IN THE METABOLISM OF LORNOXICAM IN HUMANS
      Yingjie Guo, Yifan Zhang, Ying Wang, Xiaoyan Chen, Dayong Si, Dafang Zhong, J. Paul Fawcett and Hui Zhou
      Drug Metabolism and Disposition June 2005, 33 (6) 749-753; DOI: https://doi.org/10.1124/dmd.105.003616

  6. Gupta, Anshul

    1. FUNCTIONAL ANALYSIS OF THE HUMAN VARIANTS OF BREAST CANCER RESISTANCE PROTEIN: I206L, N590Y, AND D620N
      R. Robert Vethanayagam, Honggang Wang, Anshul Gupta, Yi Zhang, Fred Lewis, Jashvant D. Unadkat and Qingcheng Mao
      Drug Metabolism and Disposition June 2005, 33 (6) 697-705; DOI: https://doi.org/10.1124/dmd.105.003657

H

  1. Hallifax, David

    1. IMPACT OF PARALLEL PATHWAYS OF DRUG ELIMINATION AND MULTIPLE CYTOCHROME P450 INVOLVEMENT ON DRUG-DRUG INTERACTIONS: CYP2D6 PARADIGM
      Kiyomi Ito, David Hallifax, R. Scott Obach and J. Brian Houston
      Drug Metabolism and Disposition June 2005, 33 (6) 837-844; DOI: https://doi.org/10.1124/dmd.105.003715

  2. Hallin, Ingrid

    1. CYTOCHROME P450 3A4 IS THE MAJOR ENZYME RESPONSIBLE FOR THE METABOLISM OF LAQUINIMOD, A NOVEL IMMUNOMODULATOR
      Helén Tuvesson, Ingrid Hallin, Robert Persson, Birgitta Sparre, Per Olov Gunnarsson and Janeric Seidegård
      Drug Metabolism and Disposition June 2005, 33 (6) 866-872; DOI: https://doi.org/10.1124/dmd.104.002238

  3. Hamamoto, Hiromi

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

  4. Hartmann, Georgy

    1. IMPACT OF ENDOTOXIN-INDUCED CHANGES IN P-GLYCOPROTEIN EXPRESSION ON DISPOSITION OF DOXORUBICIN IN MICE
      Georgy Hartmann, Vessela Vassileva and Micheline Piquette-Miller
      Drug Metabolism and Disposition June 2005, 33 (6) 820-828; DOI: https://doi.org/10.1124/dmd.104.002568

  5. Hasinoff, Brian B.

    1. METABOLISM OF THE CARDIOPROTECTIVE DRUG DEXRAZOXANE AND ONE OF ITS METABOLITES BY ISOLATED RAT MYOCYTES, HEPATOCYTES, AND BLOOD
      Patricia E. Schroeder, Gu-Qi Wang, Frank J. Burczynski and Brian B. Hasinoff
      Drug Metabolism and Disposition June 2005, 33 (6) 719-725; DOI: https://doi.org/10.1124/dmd.104.003186

  6. Hollenberg, Paul F.

    1. THE NATURALLY OCCURRING CYTOCHROME P450 (P450) 2B6 K262R MUTANT OF P450 2B6 EXHIBITS ALTERATIONS IN SUBSTRATE METABOLISM AND INACTIVATION
      Namandjé N. Bumpus, Chitra Sridar, Ute M. Kent and Paul F. Hollenberg
      Drug Metabolism and Disposition June 2005, 33 (6) 795-802; DOI: https://doi.org/10.1124/dmd.105.003749

  7. Horie, Toru

    1. IN VIVO INDUCTION OF HUMAN CYTOCHROME P450 ENZYMES EXPRESSED IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2005, 33 (6) 754-763; DOI: https://doi.org/10.1124/dmd.104.002600

  8. Horie, Toshiharu

    1. ACYL GLUCURONIDATION OF FLUOROQUINOLONE ANTIBIOTICS BY THE UDP-GLUCURONOSYLTRANSFERASE 1A SUBFAMILY IN HUMAN LIVER MICROSOMES
      Masaya Tachibana, Makoto Tanaka, Yasuhiro Masubuchi and Toshiharu Horie
      Drug Metabolism and Disposition June 2005, 33 (6) 803-811; DOI: https://doi.org/10.1124/dmd.104.003178

  9. Houston, J. Brian

    1. IMPACT OF PARALLEL PATHWAYS OF DRUG ELIMINATION AND MULTIPLE CYTOCHROME P450 INVOLVEMENT ON DRUG-DRUG INTERACTIONS: CYP2D6 PARADIGM
      Kiyomi Ito, David Hallifax, R. Scott Obach and J. Brian Houston
      Drug Metabolism and Disposition June 2005, 33 (6) 837-844; DOI: https://doi.org/10.1124/dmd.105.003715

  10. Hsieh, Frank

    1. HUMAN METABOLISM OF THE PROTEASOME INHIBITOR BORTEZOMIB: IDENTIFICATION OF CIRCULATING METABOLITES
      Teresa Pekol, J. Scott Daniels, Jason Labutti, Ian Parsons, Darrell Nix, Elizabeth Baronas, Frank Hsieh, Liang-Shang Gan and Gerald Miwa
      Drug Metabolism and Disposition June 2005, 33 (6) 771-777; DOI: https://doi.org/10.1124/dmd.104.002956

  11. Hu, Ming

    1. SPECIES- AND DISPOSITION MODEL-DEPENDENT METABOLISM OF RALOXIFENE IN GUT AND LIVER: ROLE OF UGT1A10
      Eun Ju Jeong, Yong Liu, Huimin Lin and Ming Hu
      Drug Metabolism and Disposition June 2005, 33 (6) 785-794; DOI: https://doi.org/10.1124/dmd.104.001883

  12. Huebert, Norman

    1. DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES
      Zhengyin Yan, Jian Li, Norman Huebert, Gary W. Caldwell, Yanming Du and Hua Zhong
      Drug Metabolism and Disposition June 2005, 33 (6) 706-713; DOI: https://doi.org/10.1124/dmd.104.003095

I

  1. Inouye, Kuniyo

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

  2. Ito, Kiyomi

    1. IMPACT OF PARALLEL PATHWAYS OF DRUG ELIMINATION AND MULTIPLE CYTOCHROME P450 INVOLVEMENT ON DRUG-DRUG INTERACTIONS: CYP2D6 PARADIGM
      Kiyomi Ito, David Hallifax, R. Scott Obach and J. Brian Houston
      Drug Metabolism and Disposition June 2005, 33 (6) 837-844; DOI: https://doi.org/10.1124/dmd.105.003715

  3. Iwaki, Masahiro

    1. NONLINEAR PHARMACOKINETICS OF PROPAFENONE IN RATS AND HUMANS: APPLICATION OF A SUBSTRATE DEPLETION ASSAY USING HEPATOCYTES FOR ASSESSMENT OF NONLINEARITY
      Hiroshi Komura and Masahiro Iwaki
      Drug Metabolism and Disposition June 2005, 33 (6) 726-732; DOI: https://doi.org/10.1124/dmd.104.002550

  4. Iwasaki, Kazuhide

    1. IN VIVO INDUCTION OF HUMAN CYTOCHROME P450 ENZYMES EXPRESSED IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2005, 33 (6) 754-763; DOI: https://doi.org/10.1124/dmd.104.002600

J

  1. Jeong, Eun Ju

    1. SPECIES- AND DISPOSITION MODEL-DEPENDENT METABOLISM OF RALOXIFENE IN GUT AND LIVER: ROLE OF UGT1A10
      Eun Ju Jeong, Yong Liu, Huimin Lin and Ming Hu
      Drug Metabolism and Disposition June 2005, 33 (6) 785-794; DOI: https://doi.org/10.1124/dmd.104.001883

K

  1. Kamakura, Masaki

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

  2. Katoh, Miki

    1. IN VIVO INDUCTION OF HUMAN CYTOCHROME P450 ENZYMES EXPRESSED IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2005, 33 (6) 754-763; DOI: https://doi.org/10.1124/dmd.104.002600

  3. Kent, Ute M.

    1. THE NATURALLY OCCURRING CYTOCHROME P450 (P450) 2B6 K262R MUTANT OF P450 2B6 EXHIBITS ALTERATIONS IN SUBSTRATE METABOLISM AND INACTIVATION
      Namandjé N. Bumpus, Chitra Sridar, Ute M. Kent and Paul F. Hollenberg
      Drug Metabolism and Disposition June 2005, 33 (6) 795-802; DOI: https://doi.org/10.1124/dmd.105.003749

  4. Kittaka, Atsushi

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

  5. Komura, Hiroshi

    1. NONLINEAR PHARMACOKINETICS OF PROPAFENONE IN RATS AND HUMANS: APPLICATION OF A SUBSTRATE DEPLETION ASSAY USING HEPATOCYTES FOR ASSESSMENT OF NONLINEARITY
      Hiroshi Komura and Masahiro Iwaki
      Drug Metabolism and Disposition June 2005, 33 (6) 726-732; DOI: https://doi.org/10.1124/dmd.104.002550

  6. Kunze, Kent L.

    1. EVALUATION OF TIME-DEPENDENT INACTIVATION OF CYP3A IN CRYOPRESERVED HUMAN HEPATOCYTES
      Ping Zhao, Kent L. Kunze and Caroline A. Lee
      Drug Metabolism and Disposition June 2005, 33 (6) 853-861; DOI: https://doi.org/10.1124/dmd.104.002832

  7. Kusudo, Tatsuya

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

L

  1. Labutti, Jason

    1. HUMAN METABOLISM OF THE PROTEASOME INHIBITOR BORTEZOMIB: IDENTIFICATION OF CIRCULATING METABOLITES
      Teresa Pekol, J. Scott Daniels, Jason Labutti, Ian Parsons, Darrell Nix, Elizabeth Baronas, Frank Hsieh, Liang-Shang Gan and Gerald Miwa
      Drug Metabolism and Disposition June 2005, 33 (6) 771-777; DOI: https://doi.org/10.1124/dmd.104.002956

  2. Laufer, Ralph

    1. DETERMINATION OF DRUG GLUCURONIDATION AND UDP-GLUCURONOSYLTRANSFERASE SELECTIVITY USING A 96-WELL RADIOMETRIC ASSAY
      Annalise Di Marco, Michelle D'Antoni, Silvia Attaccalite, Pietro Carotenuto and Ralph Laufer
      Drug Metabolism and Disposition June 2005, 33 (6) 812-819; DOI: https://doi.org/10.1124/dmd.105.004333

  3. Lee, Caroline A.

    1. EVALUATION OF TIME-DEPENDENT INACTIVATION OF CYP3A IN CRYOPRESERVED HUMAN HEPATOCYTES
      Ping Zhao, Kent L. Kunze and Caroline A. Lee
      Drug Metabolism and Disposition June 2005, 33 (6) 853-861; DOI: https://doi.org/10.1124/dmd.104.002832

  4. Lewis, Fred

    1. FUNCTIONAL ANALYSIS OF THE HUMAN VARIANTS OF BREAST CANCER RESISTANCE PROTEIN: I206L, N590Y, AND D620N
      R. Robert Vethanayagam, Honggang Wang, Anshul Gupta, Yi Zhang, Fred Lewis, Jashvant D. Unadkat and Qingcheng Mao
      Drug Metabolism and Disposition June 2005, 33 (6) 697-705; DOI: https://doi.org/10.1124/dmd.105.003657

  5. Li, Jian

    1. DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES
      Zhengyin Yan, Jian Li, Norman Huebert, Gary W. Caldwell, Yanming Du and Hua Zhong
      Drug Metabolism and Disposition June 2005, 33 (6) 706-713; DOI: https://doi.org/10.1124/dmd.104.003095

  6. Lin, Huimin

    1. SPECIES- AND DISPOSITION MODEL-DEPENDENT METABOLISM OF RALOXIFENE IN GUT AND LIVER: ROLE OF UGT1A10
      Eun Ju Jeong, Yong Liu, Huimin Lin and Ming Hu
      Drug Metabolism and Disposition June 2005, 33 (6) 785-794; DOI: https://doi.org/10.1124/dmd.104.001883

  7. Liu, Yong

    1. SPECIES- AND DISPOSITION MODEL-DEPENDENT METABOLISM OF RALOXIFENE IN GUT AND LIVER: ROLE OF UGT1A10
      Eun Ju Jeong, Yong Liu, Huimin Lin and Ming Hu
      Drug Metabolism and Disposition June 2005, 33 (6) 785-794; DOI: https://doi.org/10.1124/dmd.104.001883

M

  1. Mao, Qingcheng

    1. FUNCTIONAL ANALYSIS OF THE HUMAN VARIANTS OF BREAST CANCER RESISTANCE PROTEIN: I206L, N590Y, AND D620N
      R. Robert Vethanayagam, Honggang Wang, Anshul Gupta, Yi Zhang, Fred Lewis, Jashvant D. Unadkat and Qingcheng Mao
      Drug Metabolism and Disposition June 2005, 33 (6) 697-705; DOI: https://doi.org/10.1124/dmd.105.003657

  2. Masubuchi, Yasuhiro

    1. ACYL GLUCURONIDATION OF FLUOROQUINOLONE ANTIBIOTICS BY THE UDP-GLUCURONOSYLTRANSFERASE 1A SUBFAMILY IN HUMAN LIVER MICROSOMES
      Masaya Tachibana, Makoto Tanaka, Yasuhiro Masubuchi and Toshiharu Horie
      Drug Metabolism and Disposition June 2005, 33 (6) 803-811; DOI: https://doi.org/10.1124/dmd.104.003178

  3. Matsui, Tomohito

    1. IN VIVO INDUCTION OF HUMAN CYTOCHROME P450 ENZYMES EXPRESSED IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2005, 33 (6) 754-763; DOI: https://doi.org/10.1124/dmd.104.002600

  4. Mehvar, Reza

    1. ENZYME-SELECTIVE EFFECTS OF NITRIC OXIDE ON AFFINITY AND MAXIMUM VELOCITY OF VARIOUS RAT CYTOCHROMES P450
      Ragini Vuppugalla and Reza Mehvar
      Drug Metabolism and Disposition June 2005, 33 (6) 829-836; DOI: https://doi.org/10.1124/dmd.105.003848

  5. Miwa, Gerald

    1. HUMAN METABOLISM OF THE PROTEASOME INHIBITOR BORTEZOMIB: IDENTIFICATION OF CIRCULATING METABOLITES
      Teresa Pekol, J. Scott Daniels, Jason Labutti, Ian Parsons, Darrell Nix, Elizabeth Baronas, Frank Hsieh, Liang-Shang Gan and Gerald Miwa
      Drug Metabolism and Disposition June 2005, 33 (6) 771-777; DOI: https://doi.org/10.1124/dmd.104.002956

N

  1. Nakajima, Miki

    1. IN VIVO INDUCTION OF HUMAN CYTOCHROME P450 ENZYMES EXPRESSED IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2005, 33 (6) 754-763; DOI: https://doi.org/10.1124/dmd.104.002600

  2. Nix, Darrell

    1. HUMAN METABOLISM OF THE PROTEASOME INHIBITOR BORTEZOMIB: IDENTIFICATION OF CIRCULATING METABOLITES
      Teresa Pekol, J. Scott Daniels, Jason Labutti, Ian Parsons, Darrell Nix, Elizabeth Baronas, Frank Hsieh, Liang-Shang Gan and Gerald Miwa
      Drug Metabolism and Disposition June 2005, 33 (6) 771-777; DOI: https://doi.org/10.1124/dmd.104.002956

O

  1. Obach, R. Scott

    1. IMPACT OF PARALLEL PATHWAYS OF DRUG ELIMINATION AND MULTIPLE CYTOCHROME P450 INVOLVEMENT ON DRUG-DRUG INTERACTIONS: CYP2D6 PARADIGM
      Kiyomi Ito, David Hallifax, R. Scott Obach and J. Brian Houston
      Drug Metabolism and Disposition June 2005, 33 (6) 837-844; DOI: https://doi.org/10.1124/dmd.105.003715
    2. IN VITRO-IN VIVO EXTRAPOLATION OF CYP2D6 INACTIVATION BY PAROXETINE: PREDICTION OF NONSTATIONARY PHARMACOKINETICS AND DRUG INTERACTION MAGNITUDE
      Karthik Venkatakrishnan and R. Scott Obach
      Drug Metabolism and Disposition June 2005, 33 (6) 845-852; DOI: https://doi.org/10.1124/dmd.105.004077

  2. Ohta, Miho

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

P

  1. Parsons, Ian

    1. HUMAN METABOLISM OF THE PROTEASOME INHIBITOR BORTEZOMIB: IDENTIFICATION OF CIRCULATING METABOLITES
      Teresa Pekol, J. Scott Daniels, Jason Labutti, Ian Parsons, Darrell Nix, Elizabeth Baronas, Frank Hsieh, Liang-Shang Gan and Gerald Miwa
      Drug Metabolism and Disposition June 2005, 33 (6) 771-777; DOI: https://doi.org/10.1124/dmd.104.002956

  2. Pekol, Teresa

    1. HUMAN METABOLISM OF THE PROTEASOME INHIBITOR BORTEZOMIB: IDENTIFICATION OF CIRCULATING METABOLITES
      Teresa Pekol, J. Scott Daniels, Jason Labutti, Ian Parsons, Darrell Nix, Elizabeth Baronas, Frank Hsieh, Liang-Shang Gan and Gerald Miwa
      Drug Metabolism and Disposition June 2005, 33 (6) 771-777; DOI: https://doi.org/10.1124/dmd.104.002956

  3. Perloff, Elke S.

    1. ATAZANAVIR: EFFECTS ON P-GLYCOPROTEIN TRANSPORT AND CYP3A METABOLISM IN VITRO
      Elke S. Perloff, Su X. Duan, Paul R. Skolnik, David J. Greenblatt and Lisa L. von Moltke
      Drug Metabolism and Disposition June 2005, 33 (6) 764-770; DOI: https://doi.org/10.1124/dmd.104.002931

  4. Persson, Robert

    1. CYTOCHROME P450 3A4 IS THE MAJOR ENZYME RESPONSIBLE FOR THE METABOLISM OF LAQUINIMOD, A NOVEL IMMUNOMODULATOR
      Helén Tuvesson, Ingrid Hallin, Robert Persson, Birgitta Sparre, Per Olov Gunnarsson and Janeric Seidegård
      Drug Metabolism and Disposition June 2005, 33 (6) 866-872; DOI: https://doi.org/10.1124/dmd.104.002238

  5. Piquette-Miller, Micheline

    1. IMPACT OF ENDOTOXIN-INDUCED CHANGES IN P-GLYCOPROTEIN EXPRESSION ON DISPOSITION OF DOXORUBICIN IN MICE
      Georgy Hartmann, Vessela Vassileva and Micheline Piquette-Miller
      Drug Metabolism and Disposition June 2005, 33 (6) 820-828; DOI: https://doi.org/10.1124/dmd.104.002568

  6. Press, Randall J.

    1. THE DISTRIBUTION, METABOLISM, AND ELIMINATION OF CLOFARABINE IN RATS
      Peter L. Bonate, Larry Arthaud, John Stuhler, Phyllis Yerino, Randall J. Press and James Q. Rose
      Drug Metabolism and Disposition June 2005, 33 (6) 739-748; DOI: https://doi.org/10.1124/dmd.104.002592

R

  1. Rose, James Q.

    1. THE DISTRIBUTION, METABOLISM, AND ELIMINATION OF CLOFARABINE IN RATS
      Peter L. Bonate, Larry Arthaud, John Stuhler, Phyllis Yerino, Randall J. Press and James Q. Rose
      Drug Metabolism and Disposition June 2005, 33 (6) 739-748; DOI: https://doi.org/10.1124/dmd.104.002592

S

  1. Saito, Nozomi

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

  2. Sakaki, Toshiyuki

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

  3. Schroeder, Patricia E.

    1. METABOLISM OF THE CARDIOPROTECTIVE DRUG DEXRAZOXANE AND ONE OF ITS METABOLITES BY ISOLATED RAT MYOCYTES, HEPATOCYTES, AND BLOOD
      Patricia E. Schroeder, Gu-Qi Wang, Frank J. Burczynski and Brian B. Hasinoff
      Drug Metabolism and Disposition June 2005, 33 (6) 719-725; DOI: https://doi.org/10.1124/dmd.104.003186

  4. Seidegård, Janeric

    1. CYTOCHROME P450 3A4 IS THE MAJOR ENZYME RESPONSIBLE FOR THE METABOLISM OF LAQUINIMOD, A NOVEL IMMUNOMODULATOR
      Helén Tuvesson, Ingrid Hallin, Robert Persson, Birgitta Sparre, Per Olov Gunnarsson and Janeric Seidegård
      Drug Metabolism and Disposition June 2005, 33 (6) 866-872; DOI: https://doi.org/10.1124/dmd.104.002238

  5. Si, Dayong

    1. ROLE OF CYP2C9 AND ITS VARIANTS (CYP2C9*3 AND CYP2C9*13) IN THE METABOLISM OF LORNOXICAM IN HUMANS
      Yingjie Guo, Yifan Zhang, Ying Wang, Xiaoyan Chen, Dayong Si, Dafang Zhong, J. Paul Fawcett and Hui Zhou
      Drug Metabolism and Disposition June 2005, 33 (6) 749-753; DOI: https://doi.org/10.1124/dmd.105.003616

  6. Silver, I. S.

    1. METABOLIC ACTIVATION OF PIOGLITAZONE IDENTIFIED FROM RAT AND HUMAN LIVER MICROSOMES AND FRESHLY ISOLATED HEPATOCYTES
      T. M. Baughman, R. A. Graham, K. Wells-Knecht, I. S. Silver, L. O. Tyler, M. Wells-Knecht and Z. Zhao
      Drug Metabolism and Disposition June 2005, 33 (6) 733-738; DOI: https://doi.org/10.1124/dmd.104.002683

  7. Skipper, Paul L.

    1. CHARACTERIZATION OF TESTOSTERONE 11β-HYDROXYLATION CATALYZED BY HUMAN LIVER MICROSOMAL CYTOCHROMES P450
      Man Ho Choi, Paul L. Skipper, John S. Wishnok and Steven R. Tannenbaum
      Drug Metabolism and Disposition June 2005, 33 (6) 714-718; DOI: https://doi.org/10.1124/dmd.104.003327

  8. Skolnik, Paul R.

    1. ATAZANAVIR: EFFECTS ON P-GLYCOPROTEIN TRANSPORT AND CYP3A METABOLISM IN VITRO
      Elke S. Perloff, Su X. Duan, Paul R. Skolnik, David J. Greenblatt and Lisa L. von Moltke
      Drug Metabolism and Disposition June 2005, 33 (6) 764-770; DOI: https://doi.org/10.1124/dmd.104.002931

  9. Soeno, Yoshinori

    1. IN VIVO INDUCTION OF HUMAN CYTOCHROME P450 ENZYMES EXPRESSED IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2005, 33 (6) 754-763; DOI: https://doi.org/10.1124/dmd.104.002600

  10. Souček, Pavel

    1. MINIPIG CYTOCHROME P450 2E1: COMPARISON WITH HUMAN ENZYME
      Jana Baranová, Eva Anzenbacherová, Pavel Anzenbacher and Pavel Souček
      Drug Metabolism and Disposition June 2005, 33 (6) 862-865; DOI: https://doi.org/10.1124/dmd.104.003392

  11. Sparre, Birgitta

    1. CYTOCHROME P450 3A4 IS THE MAJOR ENZYME RESPONSIBLE FOR THE METABOLISM OF LAQUINIMOD, A NOVEL IMMUNOMODULATOR
      Helén Tuvesson, Ingrid Hallin, Robert Persson, Birgitta Sparre, Per Olov Gunnarsson and Janeric Seidegård
      Drug Metabolism and Disposition June 2005, 33 (6) 866-872; DOI: https://doi.org/10.1124/dmd.104.002238

  12. Sridar, Chitra

    1. THE NATURALLY OCCURRING CYTOCHROME P450 (P450) 2B6 K262R MUTANT OF P450 2B6 EXHIBITS ALTERATIONS IN SUBSTRATE METABOLISM AND INACTIVATION
      Namandjé N. Bumpus, Chitra Sridar, Ute M. Kent and Paul F. Hollenberg
      Drug Metabolism and Disposition June 2005, 33 (6) 795-802; DOI: https://doi.org/10.1124/dmd.105.003749

  13. Stuhler, John

    1. THE DISTRIBUTION, METABOLISM, AND ELIMINATION OF CLOFARABINE IN RATS
      Peter L. Bonate, Larry Arthaud, John Stuhler, Phyllis Yerino, Randall J. Press and James Q. Rose
      Drug Metabolism and Disposition June 2005, 33 (6) 739-748; DOI: https://doi.org/10.1124/dmd.104.002592

  14. Suhara, Yoshitomo

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

T

  1. Tachibana, Masaya

    1. ACYL GLUCURONIDATION OF FLUOROQUINOLONE ANTIBIOTICS BY THE UDP-GLUCURONOSYLTRANSFERASE 1A SUBFAMILY IN HUMAN LIVER MICROSOMES
      Masaya Tachibana, Makoto Tanaka, Yasuhiro Masubuchi and Toshiharu Horie
      Drug Metabolism and Disposition June 2005, 33 (6) 803-811; DOI: https://doi.org/10.1124/dmd.104.003178

  2. Takayama, Hiroaki

    1. METABOLISM OF 2α-PROPOXY-1α,25-DIHYDROXYVITAMIN D3 AND 2α-(3-HYDROXYPROPOXY)-1α,25-DIHYDROXYVITAMIN D3 BY HUMAN CYP27A1 AND CYP24A1
      Daisuke Abe, Toshiyuki Sakaki, Tatsuya Kusudo, Atsushi Kittaka, Nozomi Saito, Yoshitomo Suhara, Toshie Fujishima, Hiroaki Takayama, Hiromi Hamamoto, Masaki Kamakura, Miho Ohta and Kuniyo Inouye
      Drug Metabolism and Disposition June 2005, 33 (6) 778-784; DOI: https://doi.org/10.1124/dmd.104.003038

  3. Tanaka, Makoto

    1. ACYL GLUCURONIDATION OF FLUOROQUINOLONE ANTIBIOTICS BY THE UDP-GLUCURONOSYLTRANSFERASE 1A SUBFAMILY IN HUMAN LIVER MICROSOMES
      Masaya Tachibana, Makoto Tanaka, Yasuhiro Masubuchi and Toshiharu Horie
      Drug Metabolism and Disposition June 2005, 33 (6) 803-811; DOI: https://doi.org/10.1124/dmd.104.003178

  4. Tannenbaum, Steven R.

    1. CHARACTERIZATION OF TESTOSTERONE 11β-HYDROXYLATION CATALYZED BY HUMAN LIVER MICROSOMAL CYTOCHROMES P450
      Man Ho Choi, Paul L. Skipper, John S. Wishnok and Steven R. Tannenbaum
      Drug Metabolism and Disposition June 2005, 33 (6) 714-718; DOI: https://doi.org/10.1124/dmd.104.003327

  5. Tateno, Chise

    1. IN VIVO INDUCTION OF HUMAN CYTOCHROME P450 ENZYMES EXPRESSED IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2005, 33 (6) 754-763; DOI: https://doi.org/10.1124/dmd.104.002600

  6. Tuvesson, Helén

    1. CYTOCHROME P450 3A4 IS THE MAJOR ENZYME RESPONSIBLE FOR THE METABOLISM OF LAQUINIMOD, A NOVEL IMMUNOMODULATOR
      Helén Tuvesson, Ingrid Hallin, Robert Persson, Birgitta Sparre, Per Olov Gunnarsson and Janeric Seidegård
      Drug Metabolism and Disposition June 2005, 33 (6) 866-872; DOI: https://doi.org/10.1124/dmd.104.002238

  7. Tyler, L. O.

    1. METABOLIC ACTIVATION OF PIOGLITAZONE IDENTIFIED FROM RAT AND HUMAN LIVER MICROSOMES AND FRESHLY ISOLATED HEPATOCYTES
      T. M. Baughman, R. A. Graham, K. Wells-Knecht, I. S. Silver, L. O. Tyler, M. Wells-Knecht and Z. Zhao
      Drug Metabolism and Disposition June 2005, 33 (6) 733-738; DOI: https://doi.org/10.1124/dmd.104.002683

U

  1. Unadkat, Jashvant D.

    1. FUNCTIONAL ANALYSIS OF THE HUMAN VARIANTS OF BREAST CANCER RESISTANCE PROTEIN: I206L, N590Y, AND D620N
      R. Robert Vethanayagam, Honggang Wang, Anshul Gupta, Yi Zhang, Fred Lewis, Jashvant D. Unadkat and Qingcheng Mao
      Drug Metabolism and Disposition June 2005, 33 (6) 697-705; DOI: https://doi.org/10.1124/dmd.105.003657

V

  1. Vassileva, Vessela

    1. IMPACT OF ENDOTOXIN-INDUCED CHANGES IN P-GLYCOPROTEIN EXPRESSION ON DISPOSITION OF DOXORUBICIN IN MICE
      Georgy Hartmann, Vessela Vassileva and Micheline Piquette-Miller
      Drug Metabolism and Disposition June 2005, 33 (6) 820-828; DOI: https://doi.org/10.1124/dmd.104.002568

  2. Venkatakrishnan, Karthik

    1. IN VITRO-IN VIVO EXTRAPOLATION OF CYP2D6 INACTIVATION BY PAROXETINE: PREDICTION OF NONSTATIONARY PHARMACOKINETICS AND DRUG INTERACTION MAGNITUDE
      Karthik Venkatakrishnan and R. Scott Obach
      Drug Metabolism and Disposition June 2005, 33 (6) 845-852; DOI: https://doi.org/10.1124/dmd.105.004077

  3. Vethanayagam, R. Robert

    1. FUNCTIONAL ANALYSIS OF THE HUMAN VARIANTS OF BREAST CANCER RESISTANCE PROTEIN: I206L, N590Y, AND D620N
      R. Robert Vethanayagam, Honggang Wang, Anshul Gupta, Yi Zhang, Fred Lewis, Jashvant D. Unadkat and Qingcheng Mao
      Drug Metabolism and Disposition June 2005, 33 (6) 697-705; DOI: https://doi.org/10.1124/dmd.105.003657

  4. von Moltke, Lisa L.

    1. ATAZANAVIR: EFFECTS ON P-GLYCOPROTEIN TRANSPORT AND CYP3A METABOLISM IN VITRO
      Elke S. Perloff, Su X. Duan, Paul R. Skolnik, David J. Greenblatt and Lisa L. von Moltke
      Drug Metabolism and Disposition June 2005, 33 (6) 764-770; DOI: https://doi.org/10.1124/dmd.104.002931

  5. Vuppugalla, Ragini

    1. ENZYME-SELECTIVE EFFECTS OF NITRIC OXIDE ON AFFINITY AND MAXIMUM VELOCITY OF VARIOUS RAT CYTOCHROMES P450
      Ragini Vuppugalla and Reza Mehvar
      Drug Metabolism and Disposition June 2005, 33 (6) 829-836; DOI: https://doi.org/10.1124/dmd.105.003848

W

  1. Wang, Gu-Qi

    1. METABOLISM OF THE CARDIOPROTECTIVE DRUG DEXRAZOXANE AND ONE OF ITS METABOLITES BY ISOLATED RAT MYOCYTES, HEPATOCYTES, AND BLOOD
      Patricia E. Schroeder, Gu-Qi Wang, Frank J. Burczynski and Brian B. Hasinoff
      Drug Metabolism and Disposition June 2005, 33 (6) 719-725; DOI: https://doi.org/10.1124/dmd.104.003186

  2. Wang, Honggang

    1. FUNCTIONAL ANALYSIS OF THE HUMAN VARIANTS OF BREAST CANCER RESISTANCE PROTEIN: I206L, N590Y, AND D620N
      R. Robert Vethanayagam, Honggang Wang, Anshul Gupta, Yi Zhang, Fred Lewis, Jashvant D. Unadkat and Qingcheng Mao
      Drug Metabolism and Disposition June 2005, 33 (6) 697-705; DOI: https://doi.org/10.1124/dmd.105.003657

  3. Wang, Ying

    1. ROLE OF CYP2C9 AND ITS VARIANTS (CYP2C9*3 AND CYP2C9*13) IN THE METABOLISM OF LORNOXICAM IN HUMANS
      Yingjie Guo, Yifan Zhang, Ying Wang, Xiaoyan Chen, Dayong Si, Dafang Zhong, J. Paul Fawcett and Hui Zhou
      Drug Metabolism and Disposition June 2005, 33 (6) 749-753; DOI: https://doi.org/10.1124/dmd.105.003616

  4. Wells-Knecht, K.

    1. METABOLIC ACTIVATION OF PIOGLITAZONE IDENTIFIED FROM RAT AND HUMAN LIVER MICROSOMES AND FRESHLY ISOLATED HEPATOCYTES
      T. M. Baughman, R. A. Graham, K. Wells-Knecht, I. S. Silver, L. O. Tyler, M. Wells-Knecht and Z. Zhao
      Drug Metabolism and Disposition June 2005, 33 (6) 733-738; DOI: https://doi.org/10.1124/dmd.104.002683

  5. Wells-Knecht, M.

    1. METABOLIC ACTIVATION OF PIOGLITAZONE IDENTIFIED FROM RAT AND HUMAN LIVER MICROSOMES AND FRESHLY ISOLATED HEPATOCYTES
      T. M. Baughman, R. A. Graham, K. Wells-Knecht, I. S. Silver, L. O. Tyler, M. Wells-Knecht and Z. Zhao
      Drug Metabolism and Disposition June 2005, 33 (6) 733-738; DOI: https://doi.org/10.1124/dmd.104.002683

  6. Wishnok, John S.

    1. CHARACTERIZATION OF TESTOSTERONE 11β-HYDROXYLATION CATALYZED BY HUMAN LIVER MICROSOMAL CYTOCHROMES P450
      Man Ho Choi, Paul L. Skipper, John S. Wishnok and Steven R. Tannenbaum
      Drug Metabolism and Disposition June 2005, 33 (6) 714-718; DOI: https://doi.org/10.1124/dmd.104.003327

Y

  1. Yan, Zhengyin

    1. DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES
      Zhengyin Yan, Jian Li, Norman Huebert, Gary W. Caldwell, Yanming Du and Hua Zhong
      Drug Metabolism and Disposition June 2005, 33 (6) 706-713; DOI: https://doi.org/10.1124/dmd.104.003095

  2. Yerino, Phyllis

    1. THE DISTRIBUTION, METABOLISM, AND ELIMINATION OF CLOFARABINE IN RATS
      Peter L. Bonate, Larry Arthaud, John Stuhler, Phyllis Yerino, Randall J. Press and James Q. Rose
      Drug Metabolism and Disposition June 2005, 33 (6) 739-748; DOI: https://doi.org/10.1124/dmd.104.002592

  3. Yokoi, Tsuyoshi

    1. IN VIVO INDUCTION OF HUMAN CYTOCHROME P450 ENZYMES EXPRESSED IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2005, 33 (6) 754-763; DOI: https://doi.org/10.1124/dmd.104.002600

  4. Yoshizato, Katsutoshi

    1. IN VIVO INDUCTION OF HUMAN CYTOCHROME P450 ENZYMES EXPRESSED IN CHIMERIC MICE WITH HUMANIZED LIVER
      Miki Katoh, Tomohito Matsui, Miki Nakajima, Chise Tateno, Yoshinori Soeno, Toru Horie, Kazuhide Iwasaki, Katsutoshi Yoshizato and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2005, 33 (6) 754-763; DOI: https://doi.org/10.1124/dmd.104.002600

Z

  1. Zhang, Yi

    1. FUNCTIONAL ANALYSIS OF THE HUMAN VARIANTS OF BREAST CANCER RESISTANCE PROTEIN: I206L, N590Y, AND D620N
      R. Robert Vethanayagam, Honggang Wang, Anshul Gupta, Yi Zhang, Fred Lewis, Jashvant D. Unadkat and Qingcheng Mao
      Drug Metabolism and Disposition June 2005, 33 (6) 697-705; DOI: https://doi.org/10.1124/dmd.105.003657

  2. Zhang, Yifan

    1. ROLE OF CYP2C9 AND ITS VARIANTS (CYP2C9*3 AND CYP2C9*13) IN THE METABOLISM OF LORNOXICAM IN HUMANS
      Yingjie Guo, Yifan Zhang, Ying Wang, Xiaoyan Chen, Dayong Si, Dafang Zhong, J. Paul Fawcett and Hui Zhou
      Drug Metabolism and Disposition June 2005, 33 (6) 749-753; DOI: https://doi.org/10.1124/dmd.105.003616

  3. Zhao, Ping

    1. EVALUATION OF TIME-DEPENDENT INACTIVATION OF CYP3A IN CRYOPRESERVED HUMAN HEPATOCYTES
      Ping Zhao, Kent L. Kunze and Caroline A. Lee
      Drug Metabolism and Disposition June 2005, 33 (6) 853-861; DOI: https://doi.org/10.1124/dmd.104.002832

  4. Zhao, Z.

    1. METABOLIC ACTIVATION OF PIOGLITAZONE IDENTIFIED FROM RAT AND HUMAN LIVER MICROSOMES AND FRESHLY ISOLATED HEPATOCYTES
      T. M. Baughman, R. A. Graham, K. Wells-Knecht, I. S. Silver, L. O. Tyler, M. Wells-Knecht and Z. Zhao
      Drug Metabolism and Disposition June 2005, 33 (6) 733-738; DOI: https://doi.org/10.1124/dmd.104.002683

  5. Zhong, Dafang

    1. ROLE OF CYP2C9 AND ITS VARIANTS (CYP2C9*3 AND CYP2C9*13) IN THE METABOLISM OF LORNOXICAM IN HUMANS
      Yingjie Guo, Yifan Zhang, Ying Wang, Xiaoyan Chen, Dayong Si, Dafang Zhong, J. Paul Fawcett and Hui Zhou
      Drug Metabolism and Disposition June 2005, 33 (6) 749-753; DOI: https://doi.org/10.1124/dmd.105.003616

  6. Zhong, Hua

    1. DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES
      Zhengyin Yan, Jian Li, Norman Huebert, Gary W. Caldwell, Yanming Du and Hua Zhong
      Drug Metabolism and Disposition June 2005, 33 (6) 706-713; DOI: https://doi.org/10.1124/dmd.104.003095

  7. Zhou, Hui

    1. ROLE OF CYP2C9 AND ITS VARIANTS (CYP2C9*3 AND CYP2C9*13) IN THE METABOLISM OF LORNOXICAM IN HUMANS
      Yingjie Guo, Yifan Zhang, Ying Wang, Xiaoyan Chen, Dayong Si, Dafang Zhong, J. Paul Fawcett and Hui Zhou
      Drug Metabolism and Disposition June 2005, 33 (6) 749-753; DOI: https://doi.org/10.1124/dmd.105.003616
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