IMPACT OF PARALLEL PATHWAYS OF DRUG ELIMINATION AND MULTIPLE CYTOCHROME P450 INVOLVEMENT ON DRUG-DRUG INTERACTIONS: CYP2D6 PARADIGM

School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom (K.I., D.H., J.B.H.); and Department of Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Global Research and Development, Groton, Connecticut (R.S.O.)

Address correspondence to:
Professor J. Brian Houston, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester M13 9PL, UK. E-mail: Brian.Houston{at}manchester.ac.uk

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