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Research ArticleArticle

AUTOMATED SCREENING WITH CONFIRMATION OF MECHANISM-BASED INACTIVATION OF CYP3A4, CYP2C9, CYP2C19, CYP2D6, AND CYP1A2 IN POOLED HUMAN LIVER MICROSOMES

Heng-Keang Lim, Nicholas Duczak Jr., Linda Brougham, Michael Elliot, Krupa Patel and Kelvin Chan
Drug Metabolism and Disposition August 2005, 33 (8) 1211-1219; DOI: https://doi.org/10.1124/dmd.104.003475

Article Information

vol. 33 no. 8 1211-1219
DOI 
https://doi.org/10.1124/dmd.104.003475
PubMed 
15860655
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received December 23, 2004
  • Accepted April 27, 2005
  • Published online July 13, 2005.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Heng-Keang Lim,
  2. Nicholas Duczak, Jr.,
  3. Linda Brougham,
  4. Michael Elliot,
  5. Krupa Patel and
  6. Kelvin Chan
  1. eADME, Drug Metabolism and Pharmacokinetics, Aventis, Bridgewater, New Jersey
  1. Address correspondence to:
    Dr. Heng-Keang Lim, Johnson & Johnson Pharmaceutical Research Institute, Preclinical Pharmacokinetics, Preclinical Drug Evaluation, OCD, K-007, 1001 Route 202 North, P.O. Box 300, Raritan, NJ 08869. E-mail: hlim5{at}prdus.jnj.com
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Research ArticleArticle

AUTOMATED SCREENING WITH CONFIRMATION OF MECHANISM-BASED INACTIVATION OF CYP3A4, CYP2C9, CYP2C19, CYP2D6, AND CYP1A2 IN POOLED HUMAN LIVER MICROSOMES

Heng-Keang Lim, Nicholas Duczak, Linda Brougham, Michael Elliot, Krupa Patel and Kelvin Chan
Drug Metabolism and Disposition August 1, 2005, 33 (8) 1211-1219; DOI: https://doi.org/10.1124/dmd.104.003475
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