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PubMed
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History
- Received July 14, 2005
- Accepted October 25, 2005
- Published online December 20, 2005.
Copyright & Usage
The American Society for Pharmacology and
Experimental Therapeutics
Author Information
- Anna L. Blobaum
- Address correspondence to:
Dr. Anna L. Blobaum, Department of Biochemistry, Vanderbilt University, 854 Robinson Research Building, 23rd Avenue South at Pierce, Nashville, TN 37232. E-mail: anna.l.blobaum{at}vanderbilt.edu
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- Abstract
- Mechanism-Based Inactivation and Reversibility (Overview)
- Acetylenic Mechanism-Based Inactivators
- Unique Spectral Intermediates Formed during Reversible Inactivation
- The Role of P450 Active Site Architecture in Reversibility
- Chemical Determinants of Reversibility
- Conclusions and Future Directions
- Acknowledgments
- Footnotes
- References
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