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Research ArticleArticle

APPLICATION OF A GENERIC PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL TO THE ESTIMATION OF XENOBIOTIC LEVELS IN RAT PLASMA

F. A. Brightman, D. E. Leahy, G. E. Searle and S. Thomas
Drug Metabolism and Disposition January 2006, 34 (1) 84-93; DOI: https://doi.org/10.1124/dmd.105.004804

Article Information

vol. 34 no. 1 84-93
DOI 
https://doi.org/10.1124/dmd.105.004804
PubMed 
16221757
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 23, 2005
  • Accepted October 11, 2005
  • Published online December 20, 2005.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. F. A. Brightman,
  2. D. E. Leahy,
  3. G. E. Searle and
  4. S. Thomas
  1. Cyprotex Discovery Ltd., Macclesfield, Cheshire, United Kingdom
  1. Address correspondence to:
    Dr. David E. Leahy, Cyprotex Discovery Ltd., 13–15 Beech Lane, Macclesfield, Cheshire, United Kingdom, SK10 2DR. E-mail: d.leahy{at}cyprotex.com
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Research ArticleArticle

APPLICATION OF A GENERIC PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL TO THE ESTIMATION OF XENOBIOTIC LEVELS IN RAT PLASMA

F. A. Brightman, D. E. Leahy, G. E. Searle and S. Thomas
Drug Metabolism and Disposition January 1, 2006, 34 (1) 84-93; DOI: https://doi.org/10.1124/dmd.105.004804
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