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Research ArticleArticle

Use of Immortalized Human Hepatocytes to Predict the Magnitude of Clinical Drug-Drug Interactions Caused by CYP3A4 Induction

Sharon L. Ripp, Jessica B. Mills, Odette A. Fahmi, Kristen A. Trevena, Jennifer L. Liras, Tristan S. Maurer and Sonia M. de Morais
Drug Metabolism and Disposition October 2006, 34 (10) 1742-1748; DOI: https://doi.org/10.1124/dmd.106.010132
Sharon L. Ripp
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Jessica B. Mills
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Odette A. Fahmi
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Kristen A. Trevena
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Jennifer L. Liras
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Tristan S. Maurer
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Sonia M. de Morais
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Article Information

vol. 34 no. 10 1742-1748
DOI 
https://doi.org/10.1124/dmd.106.010132
PubMed 
16837568

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 10, 2006
  • Accepted June 30, 2006
  • Published online September 20, 2006.

Article Versions

  • Earlier version (July 12, 2006 - 08:09).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Sharon L. Ripp,
  2. Jessica B. Mills,
  3. Odette A. Fahmi,
  4. Kristen A. Trevena,
  5. Jennifer L. Liras,
  6. Tristan S. Maurer and
  7. Sonia M. de Morais
  1. Department of Pharmacokinetics, Dynamics and Metabolism (S.L.R., O.A.F., K.A.T., J.L.L., T.S.M., S.M.D.) and Department of Scientific Development (J.B.M.), Pfizer Global Research and Development, Groton Laboratories, Groton, Connecticut
  1. Address correspondence to:
    Dr. Sonia M. de Morais, Department of Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research and Development, Groton, CT 06340. E-mail: sonia.m.demorais{at}pfizer.com
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Drug Metabolism and Disposition: 34 (10)
Drug Metabolism and Disposition
Vol. 34, Issue 10
1 Oct 2006
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Research ArticleArticle

Use of Immortalized Human Hepatocytes to Predict the Magnitude of Clinical Drug-Drug Interactions Caused by CYP3A4 Induction

Sharon L. Ripp, Jessica B. Mills, Odette A. Fahmi, Kristen A. Trevena, Jennifer L. Liras, Tristan S. Maurer and Sonia M. de Morais
Drug Metabolism and Disposition October 1, 2006, 34 (10) 1742-1748; DOI: https://doi.org/10.1124/dmd.106.010132

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Research ArticleArticle

Use of Immortalized Human Hepatocytes to Predict the Magnitude of Clinical Drug-Drug Interactions Caused by CYP3A4 Induction

Sharon L. Ripp, Jessica B. Mills, Odette A. Fahmi, Kristen A. Trevena, Jennifer L. Liras, Tristan S. Maurer and Sonia M. de Morais
Drug Metabolism and Disposition October 1, 2006, 34 (10) 1742-1748; DOI: https://doi.org/10.1124/dmd.106.010132
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