Advertisement

Index by author

November 01, 2006; Volume 34,Issue 11

A

  1. Almeida, L.

    1. Human Metabolism of Nebicapone (BIA 3-202), a Novel Catechol-O-Methyltransferase Inhibitor: Characterization of in Vitro Glucuronidation
      A. I. Loureiro, M. J. Bonifácio, C. Fernandes-Lopes, L. Almeida, L. C. Wright and P. Soares-Da-Silva
      Drug Metabolism and Disposition November 2006, 34 (11) 1856-1862; DOI: https://doi.org/10.1124/dmd.106.010447

B

  1. Barbuch, Robert

    1. Disposition of [14C]Ruboxistaurin in Humans
      Jennifer L. Burkey, Kristina M. Campanale, Robert Barbuch, Douglas O'Bannon, James Rash, Charles Benson and David Small
      Drug Metabolism and Disposition November 2006, 34 (11) 1909-1917; DOI: https://doi.org/10.1124/dmd.106.009894

  2. Benson, Charles

    1. Disposition of [14C]Ruboxistaurin in Humans
      Jennifer L. Burkey, Kristina M. Campanale, Robert Barbuch, Douglas O'Bannon, James Rash, Charles Benson and David Small
      Drug Metabolism and Disposition November 2006, 34 (11) 1909-1917; DOI: https://doi.org/10.1124/dmd.106.009894

  3. Bobrowski, Walter

    1. Porcine Brain Microvessel Endothelial Cells as an in Vitro Model to Predict in Vivo Blood-Brain Barrier Permeability
      Yan Zhang, Cheryl S. W. Li, Yuyang Ye, Kjell Johnson, Julie Poe, Shannon Johnson, Walter Bobrowski, Rosario Garrido and Cherukury Madhu
      Drug Metabolism and Disposition November 2006, 34 (11) 1935-1943; DOI: https://doi.org/10.1124/dmd.105.006437

  4. Bonifácio, M. J.

    1. Human Metabolism of Nebicapone (BIA 3-202), a Novel Catechol-O-Methyltransferase Inhibitor: Characterization of in Vitro Glucuronidation
      A. I. Loureiro, M. J. Bonifácio, C. Fernandes-Lopes, L. Almeida, L. C. Wright and P. Soares-Da-Silva
      Drug Metabolism and Disposition November 2006, 34 (11) 1856-1862; DOI: https://doi.org/10.1124/dmd.106.010447

  5. Brevig, Holly

    1. Synthesis of Substituted Phenyl Diaziridines and Characterization as Mechanism-Based Inactivators of Human Cytochrome P450 2B6
      Chitra Sridar, Yoshimasa Kobayashi, Holly Brevig, Ute M. Kent, Satish G. Puppali, John M. Rimoldi and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2006, 34 (11) 1849-1855; DOI: https://doi.org/10.1124/dmd.106.010082

  6. Bu, Hai-Zhi

    1. Identification of Enzymes Responsible for Primary and Sequential Oxygenation Reactions of Capravirine in Human Liver Microsomes
      Hai-Zhi Bu, Ping Zhao, Ping Kang, William F. Pool and Ellen Y. Wu
      Drug Metabolism and Disposition November 2006, 34 (11) 1798-1802; DOI: https://doi.org/10.1124/dmd.106.011189

  7. Burkey, Jennifer L.

    1. Disposition of [14C]Ruboxistaurin in Humans
      Jennifer L. Burkey, Kristina M. Campanale, Robert Barbuch, Douglas O'Bannon, James Rash, Charles Benson and David Small
      Drug Metabolism and Disposition November 2006, 34 (11) 1909-1917; DOI: https://doi.org/10.1124/dmd.106.009894

C

  1. Campanale, Kristina M.

    1. Disposition of [14C]Ruboxistaurin in Humans
      Jennifer L. Burkey, Kristina M. Campanale, Robert Barbuch, Douglas O'Bannon, James Rash, Charles Benson and David Small
      Drug Metabolism and Disposition November 2006, 34 (11) 1909-1917; DOI: https://doi.org/10.1124/dmd.106.009894

  2. Carr, Brian

    1. Rifampin Induces the in Vitro Oxidative Metabolism, but Not the in Vivo Clearance of Diclofenac in Rhesus Monkeys
      Thomayant Prueksaritanont, Chunze Li, Cuyue Tang, Yuhsin Kuo, Kristie Strong-Basalyga and Brian Carr
      Drug Metabolism and Disposition November 2006, 34 (11) 1806-1810; DOI: https://doi.org/10.1124/dmd.106.011643

  3. Chen, Jun

    1. Disposition of Flavonoids via Enteric Recycling: Structural Effects and Lack of Correlations between in Vitro and in Situ Metabolic Properties
      Stephen W. J. Wang, Jun Chen, Xiaobin Jia, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition November 2006, 34 (11) 1837-1848; DOI: https://doi.org/10.1124/dmd.106.009910

  4. Cheng, Xingguo

    1. Regulation of mRNA Expression of Xenobiotic Transporters by the Pregnane X Receptor in Mouse Liver, Kidney, and Intestine
      Xingguo Cheng and Curtis D. Klaassen
      Drug Metabolism and Disposition November 2006, 34 (11) 1863-1867; DOI: https://doi.org/10.1124/dmd.106.010520

  5. Choi, Chang Soo

    1. Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
      Kwang-Hyeon Liu, Mi-Gyung Kim, Dong-Jun Lee, Yune-Jung Yoon, Min-Jung Kim, Ji-Hong Shon, Chang Soo Choi, Young Kil Choi, Zeuresenay Desta and Jae-Gook Shin
      Drug Metabolism and Disposition November 2006, 34 (11) 1793-1797; DOI: https://doi.org/10.1124/dmd.106.010488

  6. Choi, Young Kil

    1. Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
      Kwang-Hyeon Liu, Mi-Gyung Kim, Dong-Jun Lee, Yune-Jung Yoon, Min-Jung Kim, Ji-Hong Shon, Chang Soo Choi, Young Kil Choi, Zeuresenay Desta and Jae-Gook Shin
      Drug Metabolism and Disposition November 2006, 34 (11) 1793-1797; DOI: https://doi.org/10.1124/dmd.106.010488

  7. Cvitkovic, Esteban

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

D

  1. de Graaf, Inge A. M.

    1. Innovative Methods to Study Human Intestinal Drug Metabolism in Vitro: Precision-Cut Slices Compared with Ussing Chamber Preparations
      Esther G. van de Kerkhof, Anna-Lena B. Ungell, Åsa K. Sjöberg, Marina H. de Jager, Constanze Hilgendorf, Inge A. M. de Graaf and Geny M. M. Groothuis
      Drug Metabolism and Disposition November 2006, 34 (11) 1893-1902; DOI: https://doi.org/10.1124/dmd.106.011148

  2. de Jager, Marina H.

    1. Innovative Methods to Study Human Intestinal Drug Metabolism in Vitro: Precision-Cut Slices Compared with Ussing Chamber Preparations
      Esther G. van de Kerkhof, Anna-Lena B. Ungell, Åsa K. Sjöberg, Marina H. de Jager, Constanze Hilgendorf, Inge A. M. de Graaf and Geny M. M. Groothuis
      Drug Metabolism and Disposition November 2006, 34 (11) 1893-1902; DOI: https://doi.org/10.1124/dmd.106.011148

  3. Denner, Karsten

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

  4. Deroussent, Alain

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

  5. Desta, Zeuresenay

    1. Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
      Kwang-Hyeon Liu, Mi-Gyung Kim, Dong-Jun Lee, Yune-Jung Yoon, Min-Jung Kim, Ji-Hong Shon, Chang Soo Choi, Young Kil Choi, Zeuresenay Desta and Jae-Gook Shin
      Drug Metabolism and Disposition November 2006, 34 (11) 1793-1797; DOI: https://doi.org/10.1124/dmd.106.010488

  6. De Valeriola, Dominique

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

E

  1. Eder, Klaus

    1. Clofibrate Increases Hepatic Triiodothyronine (T3)- and Thyroxine (T4)-Glucuronosyltransferase Activities and Lowers Plasma T3 and T4 Concentrations in Pigs
      Sebastian Luci, Holger Kluge, Frank Hirche and Klaus Eder
      Drug Metabolism and Disposition November 2006, 34 (11) 1887-1892; DOI: https://doi.org/10.1124/dmd.106.011379

F

  1. Fernandes-Lopes, C.

    1. Human Metabolism of Nebicapone (BIA 3-202), a Novel Catechol-O-Methyltransferase Inhibitor: Characterization of in Vitro Glucuronidation
      A. I. Loureiro, M. J. Bonifácio, C. Fernandes-Lopes, L. Almeida, L. C. Wright and P. Soares-Da-Silva
      Drug Metabolism and Disposition November 2006, 34 (11) 1856-1862; DOI: https://doi.org/10.1124/dmd.106.010447

G

  1. Garrido, Rosario

    1. Porcine Brain Microvessel Endothelial Cells as an in Vitro Model to Predict in Vivo Blood-Brain Barrier Permeability
      Yan Zhang, Cheryl S. W. Li, Yuyang Ye, Kjell Johnson, Julie Poe, Shannon Johnson, Walter Bobrowski, Rosario Garrido and Cherukury Madhu
      Drug Metabolism and Disposition November 2006, 34 (11) 1935-1943; DOI: https://doi.org/10.1124/dmd.105.006437

  2. Groothuis, Geny M. M.

    1. Innovative Methods to Study Human Intestinal Drug Metabolism in Vitro: Precision-Cut Slices Compared with Ussing Chamber Preparations
      Esther G. van de Kerkhof, Anna-Lena B. Ungell, Åsa K. Sjöberg, Marina H. de Jager, Constanze Hilgendorf, Inge A. M. de Graaf and Geny M. M. Groothuis
      Drug Metabolism and Disposition November 2006, 34 (11) 1893-1902; DOI: https://doi.org/10.1124/dmd.106.011148

  3. Gross, Gerhard

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

  4. Gschwind, Hans-Peter

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

  5. Guenther, Clemens

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

H

  1. Hallifax, David

    1. Uptake and Intracellular Binding of Lipophilic Amine Drugs by Isolated Rat Hepatocytes and Implications for Prediction of in Vivo Metabolic Clearance
      David Hallifax and J. Brian Houston
      Drug Metabolism and Disposition November 2006, 34 (11) 1829-1836; DOI: https://doi.org/10.1124/dmd.106.010413

  2. Hayashi, Yayoi

    1. Molecular Identification and Functional Characterization of Rat Multidrug and Toxin Extrusion Type Transporter 1 as an Organic Cation/H+ Antiporter in the Kidney
      Kin-ya Ohta, Katsuhisa Inoue, Yayoi Hayashi and Hiroaki Yuasa
      Drug Metabolism and Disposition November 2006, 34 (11) 1868-1874; DOI: https://doi.org/10.1124/dmd.106.010876

  3. Hilgendorf, Constanze

    1. Innovative Methods to Study Human Intestinal Drug Metabolism in Vitro: Precision-Cut Slices Compared with Ussing Chamber Preparations
      Esther G. van de Kerkhof, Anna-Lena B. Ungell, Åsa K. Sjöberg, Marina H. de Jager, Constanze Hilgendorf, Inge A. M. de Graaf and Geny M. M. Groothuis
      Drug Metabolism and Disposition November 2006, 34 (11) 1893-1902; DOI: https://doi.org/10.1124/dmd.106.011148

  4. Hirche, Frank

    1. Clofibrate Increases Hepatic Triiodothyronine (T3)- and Thyroxine (T4)-Glucuronosyltransferase Activities and Lowers Plasma T3 and T4 Concentrations in Pigs
      Sebastian Luci, Holger Kluge, Frank Hirche and Klaus Eder
      Drug Metabolism and Disposition November 2006, 34 (11) 1887-1892; DOI: https://doi.org/10.1124/dmd.106.011379

  5. Hollenberg, Paul F.

    1. Synthesis of Substituted Phenyl Diaziridines and Characterization as Mechanism-Based Inactivators of Human Cytochrome P450 2B6
      Chitra Sridar, Yoshimasa Kobayashi, Holly Brevig, Ute M. Kent, Satish G. Puppali, John M. Rimoldi and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2006, 34 (11) 1849-1855; DOI: https://doi.org/10.1124/dmd.106.010082

  6. Houston, J. Brian

    1. Uptake and Intracellular Binding of Lipophilic Amine Drugs by Isolated Rat Hepatocytes and Implications for Prediction of in Vivo Metabolic Clearance
      David Hallifax and J. Brian Houston
      Drug Metabolism and Disposition November 2006, 34 (11) 1829-1836; DOI: https://doi.org/10.1124/dmd.106.010413

  7. Hu, Ming

    1. Disposition of Flavonoids via Enteric Recycling: Structural Effects and Lack of Correlations between in Vitro and in Situ Metabolic Properties
      Stephen W. J. Wang, Jun Chen, Xiaobin Jia, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition November 2006, 34 (11) 1837-1848; DOI: https://doi.org/10.1124/dmd.106.009910

I

  1. Inoue, Katsuhisa

    1. Molecular Identification and Functional Characterization of Rat Multidrug and Toxin Extrusion Type Transporter 1 as an Organic Cation/H+ Antiporter in the Kidney
      Kin-ya Ohta, Katsuhisa Inoue, Yayoi Hayashi and Hiroaki Yuasa
      Drug Metabolism and Disposition November 2006, 34 (11) 1868-1874; DOI: https://doi.org/10.1124/dmd.106.010876

  2. Iseki, Shoichi

    1. PDZ Adaptor Protein PDZK2 Stimulates Transport Activity of Organic Cation/Carnitine Transporter OCTN2 by Modulating Cell Surface Expression
      Chizuru Watanabe, Yukio Kato, Tomoko Sugiura, Yoshiyuki Kubo, Tomohiko Wakayama, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition November 2006, 34 (11) 1927-1934; DOI: https://doi.org/10.1124/dmd.106.010207

  3. Iwanaga, Takashi

    1. Metabolic Profile of FYX-051 (4-(5-Pyridin-4-yl-1H-[1,2,4]triazol-3-yl)pyridine-2-carbonitrile) in the Rat, Dog, Monkey, and Human: Identification of N-Glucuronides and N-Glucosides
      Takashi Nakazawa, Kengo Miyata, Koichi Omura, Takashi Iwanaga and Osamu Nagata
      Drug Metabolism and Disposition November 2006, 34 (11) 1880-1886; DOI: https://doi.org/10.1124/dmd.106.011692

J

  1. Jalava, Tarja

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

  2. Jia, Xiaobin

    1. Disposition of Flavonoids via Enteric Recycling: Structural Effects and Lack of Correlations between in Vitro and in Situ Metabolic Properties
      Stephen W. J. Wang, Jun Chen, Xiaobin Jia, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition November 2006, 34 (11) 1837-1848; DOI: https://doi.org/10.1124/dmd.106.009910

  3. Johnson, Kjell

    1. Porcine Brain Microvessel Endothelial Cells as an in Vitro Model to Predict in Vivo Blood-Brain Barrier Permeability
      Yan Zhang, Cheryl S. W. Li, Yuyang Ye, Kjell Johnson, Julie Poe, Shannon Johnson, Walter Bobrowski, Rosario Garrido and Cherukury Madhu
      Drug Metabolism and Disposition November 2006, 34 (11) 1935-1943; DOI: https://doi.org/10.1124/dmd.105.006437

  4. Johnson, Shannon

    1. Porcine Brain Microvessel Endothelial Cells as an in Vitro Model to Predict in Vivo Blood-Brain Barrier Permeability
      Yan Zhang, Cheryl S. W. Li, Yuyang Ye, Kjell Johnson, Julie Poe, Shannon Johnson, Walter Bobrowski, Rosario Garrido and Cherukury Madhu
      Drug Metabolism and Disposition November 2006, 34 (11) 1935-1943; DOI: https://doi.org/10.1124/dmd.105.006437

  5. Jost, Lorenz M.

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

K

  1. Kahatt, Carmen

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

  2. Kamimura, Hidetaka

    1. Elucidation of the Effects of the CYP1A2 Deficiency Polymorphism in the Metabolism of 4-Cyclohexyl-1-ethyl-7-methylpyrido[2,3-d]pyrimidine-2-(1H)-one (YM-64227), a Phosphodiesterase Type 4 Inhibitor, and Its Metabolites in Dogs
      Daisuke Tenmizu, Kiyoshi Noguchi and Hidetaka Kamimura
      Drug Metabolism and Disposition November 2006, 34 (11) 1811-1816; DOI: https://doi.org/10.1124/dmd.106.011213

  3. Kang, Ping

    1. Identification of Enzymes Responsible for Primary and Sequential Oxygenation Reactions of Capravirine in Human Liver Microsomes
      Hai-Zhi Bu, Ping Zhao, Ping Kang, William F. Pool and Ellen Y. Wu
      Drug Metabolism and Disposition November 2006, 34 (11) 1798-1802; DOI: https://doi.org/10.1124/dmd.106.011189

  4. Kato, Yukio

    1. PDZ Adaptor Protein PDZK2 Stimulates Transport Activity of Organic Cation/Carnitine Transporter OCTN2 by Modulating Cell Surface Expression
      Chizuru Watanabe, Yukio Kato, Tomoko Sugiura, Yoshiyuki Kubo, Tomohiko Wakayama, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition November 2006, 34 (11) 1927-1934; DOI: https://doi.org/10.1124/dmd.106.010207

  5. Kent, Ute M.

    1. Synthesis of Substituted Phenyl Diaziridines and Characterization as Mechanism-Based Inactivators of Human Cytochrome P450 2B6
      Chitra Sridar, Yoshimasa Kobayashi, Holly Brevig, Ute M. Kent, Satish G. Puppali, John M. Rimoldi and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2006, 34 (11) 1849-1855; DOI: https://doi.org/10.1124/dmd.106.010082

  6. Kim, Mi-Gyung

    1. Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
      Kwang-Hyeon Liu, Mi-Gyung Kim, Dong-Jun Lee, Yune-Jung Yoon, Min-Jung Kim, Ji-Hong Shon, Chang Soo Choi, Young Kil Choi, Zeuresenay Desta and Jae-Gook Shin
      Drug Metabolism and Disposition November 2006, 34 (11) 1793-1797; DOI: https://doi.org/10.1124/dmd.106.010488

  7. Kim, Min-Jung

    1. Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
      Kwang-Hyeon Liu, Mi-Gyung Kim, Dong-Jun Lee, Yune-Jung Yoon, Min-Jung Kim, Ji-Hong Shon, Chang Soo Choi, Young Kil Choi, Zeuresenay Desta and Jae-Gook Shin
      Drug Metabolism and Disposition November 2006, 34 (11) 1793-1797; DOI: https://doi.org/10.1124/dmd.106.010488

  8. Klaassen, Curtis D.

    1. Regulation of mRNA Expression of Xenobiotic Transporters by the Pregnane X Receptor in Mouse Liver, Kidney, and Intestine
      Xingguo Cheng and Curtis D. Klaassen
      Drug Metabolism and Disposition November 2006, 34 (11) 1863-1867; DOI: https://doi.org/10.1124/dmd.106.010520

  9. Kluge, Holger

    1. Clofibrate Increases Hepatic Triiodothyronine (T3)- and Thyroxine (T4)-Glucuronosyltransferase Activities and Lowers Plasma T3 and T4 Concentrations in Pigs
      Sebastian Luci, Holger Kluge, Frank Hirche and Klaus Eder
      Drug Metabolism and Disposition November 2006, 34 (11) 1887-1892; DOI: https://doi.org/10.1124/dmd.106.011379

  10. Kobayashi, Yoshimasa

    1. Synthesis of Substituted Phenyl Diaziridines and Characterization as Mechanism-Based Inactivators of Human Cytochrome P450 2B6
      Chitra Sridar, Yoshimasa Kobayashi, Holly Brevig, Ute M. Kent, Satish G. Puppali, John M. Rimoldi and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2006, 34 (11) 1849-1855; DOI: https://doi.org/10.1124/dmd.106.010082

  11. Kubo, Yoshiyuki

    1. PDZ Adaptor Protein PDZK2 Stimulates Transport Activity of Organic Cation/Carnitine Transporter OCTN2 by Modulating Cell Surface Expression
      Chizuru Watanabe, Yukio Kato, Tomoko Sugiura, Yoshiyuki Kubo, Tomohiko Wakayama, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition November 2006, 34 (11) 1927-1934; DOI: https://doi.org/10.1124/dmd.106.010207

  12. Kumar, Vikas

    1. Enzyme Source Effects on CYP2C9 Kinetics and Inhibition
      Vikas Kumar, Dan A. Rock, Chad J. Warren, Timothy S. Tracy and Jan L. Wahlstrom
      Drug Metabolism and Disposition November 2006, 34 (11) 1903-1908; DOI: https://doi.org/10.1124/dmd.106.010249

  13. Kuo, Yuhsin

    1. Rifampin Induces the in Vitro Oxidative Metabolism, but Not the in Vivo Clearance of Diclofenac in Rhesus Monkeys
      Thomayant Prueksaritanont, Chunze Li, Cuyue Tang, Yuhsin Kuo, Kristie Strong-Basalyga and Brian Carr
      Drug Metabolism and Disposition November 2006, 34 (11) 1806-1810; DOI: https://doi.org/10.1124/dmd.106.011643

L

  1. Laurent, Dirk

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

  2. Lee, Dong-Jun

    1. Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
      Kwang-Hyeon Liu, Mi-Gyung Kim, Dong-Jun Lee, Yune-Jung Yoon, Min-Jung Kim, Ji-Hong Shon, Chang Soo Choi, Young Kil Choi, Zeuresenay Desta and Jae-Gook Shin
      Drug Metabolism and Disposition November 2006, 34 (11) 1793-1797; DOI: https://doi.org/10.1124/dmd.106.010488

  3. Li, Cheryl S. W.

    1. Porcine Brain Microvessel Endothelial Cells as an in Vitro Model to Predict in Vivo Blood-Brain Barrier Permeability
      Yan Zhang, Cheryl S. W. Li, Yuyang Ye, Kjell Johnson, Julie Poe, Shannon Johnson, Walter Bobrowski, Rosario Garrido and Cherukury Madhu
      Drug Metabolism and Disposition November 2006, 34 (11) 1935-1943; DOI: https://doi.org/10.1124/dmd.105.006437

  4. Li, Chunze

    1. Rifampin Induces the in Vitro Oxidative Metabolism, but Not the in Vivo Clearance of Diclofenac in Rhesus Monkeys
      Thomayant Prueksaritanont, Chunze Li, Cuyue Tang, Yuhsin Kuo, Kristie Strong-Basalyga and Brian Carr
      Drug Metabolism and Disposition November 2006, 34 (11) 1806-1810; DOI: https://doi.org/10.1124/dmd.106.011643

  5. Liu, Kwang-Hyeon

    1. Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
      Kwang-Hyeon Liu, Mi-Gyung Kim, Dong-Jun Lee, Yune-Jung Yoon, Min-Jung Kim, Ji-Hong Shon, Chang Soo Choi, Young Kil Choi, Zeuresenay Desta and Jae-Gook Shin
      Drug Metabolism and Disposition November 2006, 34 (11) 1793-1797; DOI: https://doi.org/10.1124/dmd.106.010488

  6. Lokiec, François

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

  7. Loureiro, A. I.

    1. Human Metabolism of Nebicapone (BIA 3-202), a Novel Catechol-O-Methyltransferase Inhibitor: Characterization of in Vitro Glucuronidation
      A. I. Loureiro, M. J. Bonifácio, C. Fernandes-Lopes, L. Almeida, L. C. Wright and P. Soares-Da-Silva
      Drug Metabolism and Disposition November 2006, 34 (11) 1856-1862; DOI: https://doi.org/10.1124/dmd.106.010447

  8. Luci, Sebastian

    1. Clofibrate Increases Hepatic Triiodothyronine (T3)- and Thyroxine (T4)-Glucuronosyltransferase Activities and Lowers Plasma T3 and T4 Concentrations in Pigs
      Sebastian Luci, Holger Kluge, Frank Hirche and Klaus Eder
      Drug Metabolism and Disposition November 2006, 34 (11) 1887-1892; DOI: https://doi.org/10.1124/dmd.106.011379

M

  1. Madhu, Cherukury

    1. Porcine Brain Microvessel Endothelial Cells as an in Vitro Model to Predict in Vivo Blood-Brain Barrier Permeability
      Yan Zhang, Cheryl S. W. Li, Yuyang Ye, Kjell Johnson, Julie Poe, Shannon Johnson, Walter Bobrowski, Rosario Garrido and Cherukury Madhu
      Drug Metabolism and Disposition November 2006, 34 (11) 1935-1943; DOI: https://doi.org/10.1124/dmd.105.006437

  2. Masson, Eric

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

  3. Minoshima, Masaki

    1. Rat Cytochrome P450 2C11 in Liver Microsomes Involved in Oxidation of Anesthetic Agent Propofol and Deactivated by Prior Treatment with Propofol
      Hiroshi Yamazaki, Makiko Shimizu, Takashi Nagashima, Masaki Minoshima and Norie Murayama
      Drug Metabolism and Disposition November 2006, 34 (11) 1803-1805; DOI: https://doi.org/10.1124/dmd.106.011627

  4. Miyata, Kengo

    1. Metabolic Profile of FYX-051 (4-(5-Pyridin-4-yl-1H-[1,2,4]triazol-3-yl)pyridine-2-carbonitrile) in the Rat, Dog, Monkey, and Human: Identification of N-Glucuronides and N-Glucosides
      Takashi Nakazawa, Kengo Miyata, Koichi Omura, Takashi Iwanaga and Osamu Nagata
      Drug Metabolism and Disposition November 2006, 34 (11) 1880-1886; DOI: https://doi.org/10.1124/dmd.106.011692

  5. Murayama, Norie

    1. Rat Cytochrome P450 2C11 in Liver Microsomes Involved in Oxidation of Anesthetic Agent Propofol and Deactivated by Prior Treatment with Propofol
      Hiroshi Yamazaki, Makiko Shimizu, Takashi Nagashima, Masaki Minoshima and Norie Murayama
      Drug Metabolism and Disposition November 2006, 34 (11) 1803-1805; DOI: https://doi.org/10.1124/dmd.106.011627

N

  1. Nagashima, Takashi

    1. Rat Cytochrome P450 2C11 in Liver Microsomes Involved in Oxidation of Anesthetic Agent Propofol and Deactivated by Prior Treatment with Propofol
      Hiroshi Yamazaki, Makiko Shimizu, Takashi Nagashima, Masaki Minoshima and Norie Murayama
      Drug Metabolism and Disposition November 2006, 34 (11) 1803-1805; DOI: https://doi.org/10.1124/dmd.106.011627

  2. Nagata, Osamu

    1. Metabolic Profile of FYX-051 (4-(5-Pyridin-4-yl-1H-[1,2,4]triazol-3-yl)pyridine-2-carbonitrile) in the Rat, Dog, Monkey, and Human: Identification of N-Glucuronides and N-Glucosides
      Takashi Nakazawa, Kengo Miyata, Koichi Omura, Takashi Iwanaga and Osamu Nagata
      Drug Metabolism and Disposition November 2006, 34 (11) 1880-1886; DOI: https://doi.org/10.1124/dmd.106.011692

  3. Nakazawa, Takashi

    1. Metabolic Profile of FYX-051 (4-(5-Pyridin-4-yl-1H-[1,2,4]triazol-3-yl)pyridine-2-carbonitrile) in the Rat, Dog, Monkey, and Human: Identification of N-Glucuronides and N-Glucosides
      Takashi Nakazawa, Kengo Miyata, Koichi Omura, Takashi Iwanaga and Osamu Nagata
      Drug Metabolism and Disposition November 2006, 34 (11) 1880-1886; DOI: https://doi.org/10.1124/dmd.106.011692

  4. Noguchi, Kiyoshi

    1. Elucidation of the Effects of the CYP1A2 Deficiency Polymorphism in the Metabolism of 4-Cyclohexyl-1-ethyl-7-methylpyrido[2,3-d]pyrimidine-2-(1H)-one (YM-64227), a Phosphodiesterase Type 4 Inhibitor, and Its Metabolites in Dogs
      Daisuke Tenmizu, Kiyoshi Noguchi and Hidetaka Kamimura
      Drug Metabolism and Disposition November 2006, 34 (11) 1811-1816; DOI: https://doi.org/10.1124/dmd.106.011213

O

  1. O'Bannon, Douglas

    1. Disposition of [14C]Ruboxistaurin in Humans
      Jennifer L. Burkey, Kristina M. Campanale, Robert Barbuch, Douglas O'Bannon, James Rash, Charles Benson and David Small
      Drug Metabolism and Disposition November 2006, 34 (11) 1909-1917; DOI: https://doi.org/10.1124/dmd.106.009894

  2. Ohta, Kin-ya

    1. Molecular Identification and Functional Characterization of Rat Multidrug and Toxin Extrusion Type Transporter 1 as an Organic Cation/H+ Antiporter in the Kidney
      Kin-ya Ohta, Katsuhisa Inoue, Yayoi Hayashi and Hiroaki Yuasa
      Drug Metabolism and Disposition November 2006, 34 (11) 1868-1874; DOI: https://doi.org/10.1124/dmd.106.010876

  3. Omura, Koichi

    1. Metabolic Profile of FYX-051 (4-(5-Pyridin-4-yl-1H-[1,2,4]triazol-3-yl)pyridine-2-carbonitrile) in the Rat, Dog, Monkey, and Human: Identification of N-Glucuronides and N-Glucosides
      Takashi Nakazawa, Kengo Miyata, Koichi Omura, Takashi Iwanaga and Osamu Nagata
      Drug Metabolism and Disposition November 2006, 34 (11) 1880-1886; DOI: https://doi.org/10.1124/dmd.106.011692

P

  1. Paci, Angelo

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

  2. Poe, Julie

    1. Porcine Brain Microvessel Endothelial Cells as an in Vitro Model to Predict in Vivo Blood-Brain Barrier Permeability
      Yan Zhang, Cheryl S. W. Li, Yuyang Ye, Kjell Johnson, Julie Poe, Shannon Johnson, Walter Bobrowski, Rosario Garrido and Cherukury Madhu
      Drug Metabolism and Disposition November 2006, 34 (11) 1935-1943; DOI: https://doi.org/10.1124/dmd.105.006437

  3. Pool, William F.

    1. Identification of Enzymes Responsible for Primary and Sequential Oxygenation Reactions of Capravirine in Human Liver Microsomes
      Hai-Zhi Bu, Ping Zhao, Ping Kang, William F. Pool and Ellen Y. Wu
      Drug Metabolism and Disposition November 2006, 34 (11) 1798-1802; DOI: https://doi.org/10.1124/dmd.106.011189

  4. Prueksaritanont, Thomayant

    1. Rifampin Induces the in Vitro Oxidative Metabolism, but Not the in Vivo Clearance of Diclofenac in Rhesus Monkeys
      Thomayant Prueksaritanont, Chunze Li, Cuyue Tang, Yuhsin Kuo, Kristie Strong-Basalyga and Brian Carr
      Drug Metabolism and Disposition November 2006, 34 (11) 1806-1810; DOI: https://doi.org/10.1124/dmd.106.011643

  5. Puppali, Satish G.

    1. Synthesis of Substituted Phenyl Diaziridines and Characterization as Mechanism-Based Inactivators of Human Cytochrome P450 2B6
      Chitra Sridar, Yoshimasa Kobayashi, Holly Brevig, Ute M. Kent, Satish G. Puppali, John M. Rimoldi and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2006, 34 (11) 1849-1855; DOI: https://doi.org/10.1124/dmd.106.010082

R

  1. Rash, James

    1. Disposition of [14C]Ruboxistaurin in Humans
      Jennifer L. Burkey, Kristina M. Campanale, Robert Barbuch, Douglas O'Bannon, James Rash, Charles Benson and David Small
      Drug Metabolism and Disposition November 2006, 34 (11) 1909-1917; DOI: https://doi.org/10.1124/dmd.106.009894

  2. Re, Micheline

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

  3. Rezai, Keyvan

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

  4. Rimoldi, John M.

    1. Synthesis of Substituted Phenyl Diaziridines and Characterization as Mechanism-Based Inactivators of Human Cytochrome P450 2B6
      Chitra Sridar, Yoshimasa Kobayashi, Holly Brevig, Ute M. Kent, Satish G. Puppali, John M. Rimoldi and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2006, 34 (11) 1849-1855; DOI: https://doi.org/10.1124/dmd.106.010082

  5. Rock, Dan A.

    1. Enzyme Source Effects on CYP2C9 Kinetics and Inhibition
      Vikas Kumar, Dan A. Rock, Chad J. Warren, Timothy S. Tracy and Jan L. Wahlstrom
      Drug Metabolism and Disposition November 2006, 34 (11) 1903-1908; DOI: https://doi.org/10.1124/dmd.106.010249

  6. Rottmann, Antje

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

S

  1. Shah, Ajit

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

  2. Shimizu, Makiko

    1. Rat Cytochrome P450 2C11 in Liver Microsomes Involved in Oxidation of Anesthetic Agent Propofol and Deactivated by Prior Treatment with Propofol
      Hiroshi Yamazaki, Makiko Shimizu, Takashi Nagashima, Masaki Minoshima and Norie Murayama
      Drug Metabolism and Disposition November 2006, 34 (11) 1803-1805; DOI: https://doi.org/10.1124/dmd.106.011627

  3. Shimizu, Mikiko

    1. Lack of Dose-Dependent Effects of Itraconazole on the Pharmacokinetic Interaction with Fexofenadine
      Tsukasa Uno, Mikiko Shimizu, Kazunobu Sugawara and Tomonori Tateishi
      Drug Metabolism and Disposition November 2006, 34 (11) 1875-1879; DOI: https://doi.org/10.1124/dmd.106.011023

  4. Shin, Jae-Gook

    1. Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
      Kwang-Hyeon Liu, Mi-Gyung Kim, Dong-Jun Lee, Yune-Jung Yoon, Min-Jung Kim, Ji-Hong Shon, Chang Soo Choi, Young Kil Choi, Zeuresenay Desta and Jae-Gook Shin
      Drug Metabolism and Disposition November 2006, 34 (11) 1793-1797; DOI: https://doi.org/10.1124/dmd.106.010488

  5. Shon, Ji-Hong

    1. Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
      Kwang-Hyeon Liu, Mi-Gyung Kim, Dong-Jun Lee, Yune-Jung Yoon, Min-Jung Kim, Ji-Hong Shon, Chang Soo Choi, Young Kil Choi, Zeuresenay Desta and Jae-Gook Shin
      Drug Metabolism and Disposition November 2006, 34 (11) 1793-1797; DOI: https://doi.org/10.1124/dmd.106.010488

  6. Sjöberg, Åsa K.

    1. Innovative Methods to Study Human Intestinal Drug Metabolism in Vitro: Precision-Cut Slices Compared with Ussing Chamber Preparations
      Esther G. van de Kerkhof, Anna-Lena B. Ungell, Åsa K. Sjöberg, Marina H. de Jager, Constanze Hilgendorf, Inge A. M. de Graaf and Geny M. M. Groothuis
      Drug Metabolism and Disposition November 2006, 34 (11) 1893-1902; DOI: https://doi.org/10.1124/dmd.106.011148

  7. Small, David

    1. Disposition of [14C]Ruboxistaurin in Humans
      Jennifer L. Burkey, Kristina M. Campanale, Robert Barbuch, Douglas O'Bannon, James Rash, Charles Benson and David Small
      Drug Metabolism and Disposition November 2006, 34 (11) 1909-1917; DOI: https://doi.org/10.1124/dmd.106.009894

  8. Soares-Da-Silva, P.

    1. Human Metabolism of Nebicapone (BIA 3-202), a Novel Catechol-O-Methyltransferase Inhibitor: Characterization of in Vitro Glucuronidation
      A. I. Loureiro, M. J. Bonifácio, C. Fernandes-Lopes, L. Almeida, L. C. Wright and P. Soares-Da-Silva
      Drug Metabolism and Disposition November 2006, 34 (11) 1856-1862; DOI: https://doi.org/10.1124/dmd.106.010447

  9. Souppart, Claire

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

  10. Sridar, Chitra

    1. Synthesis of Substituted Phenyl Diaziridines and Characterization as Mechanism-Based Inactivators of Human Cytochrome P450 2B6
      Chitra Sridar, Yoshimasa Kobayashi, Holly Brevig, Ute M. Kent, Satish G. Puppali, John M. Rimoldi and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2006, 34 (11) 1849-1855; DOI: https://doi.org/10.1124/dmd.106.010082

  11. Strong-Basalyga, Kristie

    1. Rifampin Induces the in Vitro Oxidative Metabolism, but Not the in Vivo Clearance of Diclofenac in Rhesus Monkeys
      Thomayant Prueksaritanont, Chunze Li, Cuyue Tang, Yuhsin Kuo, Kristie Strong-Basalyga and Brian Carr
      Drug Metabolism and Disposition November 2006, 34 (11) 1806-1810; DOI: https://doi.org/10.1124/dmd.106.011643

  12. Sugawara, Kazunobu

    1. Lack of Dose-Dependent Effects of Itraconazole on the Pharmacokinetic Interaction with Fexofenadine
      Tsukasa Uno, Mikiko Shimizu, Kazunobu Sugawara and Tomonori Tateishi
      Drug Metabolism and Disposition November 2006, 34 (11) 1875-1879; DOI: https://doi.org/10.1124/dmd.106.011023

  13. Sugiura, Tomoko

    1. PDZ Adaptor Protein PDZK2 Stimulates Transport Activity of Organic Cation/Carnitine Transporter OCTN2 by Modulating Cell Surface Expression
      Chizuru Watanabe, Yukio Kato, Tomoko Sugiura, Yoshiyuki Kubo, Tomohiko Wakayama, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition November 2006, 34 (11) 1927-1934; DOI: https://doi.org/10.1124/dmd.106.010207

T

  1. Tam, Vincent H.

    1. Disposition of Flavonoids via Enteric Recycling: Structural Effects and Lack of Correlations between in Vitro and in Situ Metabolic Properties
      Stephen W. J. Wang, Jun Chen, Xiaobin Jia, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition November 2006, 34 (11) 1837-1848; DOI: https://doi.org/10.1124/dmd.106.009910

  2. Tang, Cuyue

    1. Rifampin Induces the in Vitro Oxidative Metabolism, but Not the in Vivo Clearance of Diclofenac in Rhesus Monkeys
      Thomayant Prueksaritanont, Chunze Li, Cuyue Tang, Yuhsin Kuo, Kristie Strong-Basalyga and Brian Carr
      Drug Metabolism and Disposition November 2006, 34 (11) 1806-1810; DOI: https://doi.org/10.1124/dmd.106.011643

  3. Tateishi, Tomonori

    1. Lack of Dose-Dependent Effects of Itraconazole on the Pharmacokinetic Interaction with Fexofenadine
      Tsukasa Uno, Mikiko Shimizu, Kazunobu Sugawara and Tomonori Tateishi
      Drug Metabolism and Disposition November 2006, 34 (11) 1875-1879; DOI: https://doi.org/10.1124/dmd.106.011023

  4. Tenmizu, Daisuke

    1. Elucidation of the Effects of the CYP1A2 Deficiency Polymorphism in the Metabolism of 4-Cyclohexyl-1-ethyl-7-methylpyrido[2,3-d]pyrimidine-2-(1H)-one (YM-64227), a Phosphodiesterase Type 4 Inhibitor, and Its Metabolites in Dogs
      Daisuke Tenmizu, Kiyoshi Noguchi and Hidetaka Kamimura
      Drug Metabolism and Disposition November 2006, 34 (11) 1811-1816; DOI: https://doi.org/10.1124/dmd.106.011213

  5. Tracy, Timothy S.

    1. Enzyme Source Effects on CYP2C9 Kinetics and Inhibition
      Vikas Kumar, Dan A. Rock, Chad J. Warren, Timothy S. Tracy and Jan L. Wahlstrom
      Drug Metabolism and Disposition November 2006, 34 (11) 1903-1908; DOI: https://doi.org/10.1124/dmd.106.010249

  6. Tsuji, Akira

    1. PDZ Adaptor Protein PDZK2 Stimulates Transport Activity of Organic Cation/Carnitine Transporter OCTN2 by Modulating Cell Surface Expression
      Chizuru Watanabe, Yukio Kato, Tomoko Sugiura, Yoshiyuki Kubo, Tomohiko Wakayama, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition November 2006, 34 (11) 1927-1934; DOI: https://doi.org/10.1124/dmd.106.010207

U

  1. Ungell, Anna-Lena B.

    1. Innovative Methods to Study Human Intestinal Drug Metabolism in Vitro: Precision-Cut Slices Compared with Ussing Chamber Preparations
      Esther G. van de Kerkhof, Anna-Lena B. Ungell, Åsa K. Sjöberg, Marina H. de Jager, Constanze Hilgendorf, Inge A. M. de Graaf and Geny M. M. Groothuis
      Drug Metabolism and Disposition November 2006, 34 (11) 1893-1902; DOI: https://doi.org/10.1124/dmd.106.011148

  2. Uno, Tsukasa

    1. Lack of Dose-Dependent Effects of Itraconazole on the Pharmacokinetic Interaction with Fexofenadine
      Tsukasa Uno, Mikiko Shimizu, Kazunobu Sugawara and Tomonori Tateishi
      Drug Metabolism and Disposition November 2006, 34 (11) 1875-1879; DOI: https://doi.org/10.1124/dmd.106.011023

V

  1. van de Kerkhof, Esther G.

    1. Innovative Methods to Study Human Intestinal Drug Metabolism in Vitro: Precision-Cut Slices Compared with Ussing Chamber Preparations
      Esther G. van de Kerkhof, Anna-Lena B. Ungell, Åsa K. Sjöberg, Marina H. de Jager, Constanze Hilgendorf, Inge A. M. de Graaf and Geny M. M. Groothuis
      Drug Metabolism and Disposition November 2006, 34 (11) 1893-1902; DOI: https://doi.org/10.1124/dmd.106.011148

  2. Vassal, Gilles

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

W

  1. Wahlstrom, Jan L.

    1. Enzyme Source Effects on CYP2C9 Kinetics and Inhibition
      Vikas Kumar, Dan A. Rock, Chad J. Warren, Timothy S. Tracy and Jan L. Wahlstrom
      Drug Metabolism and Disposition November 2006, 34 (11) 1903-1908; DOI: https://doi.org/10.1124/dmd.106.010249

  2. Wakayama, Tomohiko

    1. PDZ Adaptor Protein PDZK2 Stimulates Transport Activity of Organic Cation/Carnitine Transporter OCTN2 by Modulating Cell Surface Expression
      Chizuru Watanabe, Yukio Kato, Tomoko Sugiura, Yoshiyuki Kubo, Tomohiko Wakayama, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition November 2006, 34 (11) 1927-1934; DOI: https://doi.org/10.1124/dmd.106.010207

  3. Waldmeier, Felix

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

  4. Wang, Stephen W. J.

    1. Disposition of Flavonoids via Enteric Recycling: Structural Effects and Lack of Correlations between in Vitro and in Situ Metabolic Properties
      Stephen W. J. Wang, Jun Chen, Xiaobin Jia, Vincent H. Tam and Ming Hu
      Drug Metabolism and Disposition November 2006, 34 (11) 1837-1848; DOI: https://doi.org/10.1124/dmd.106.009910

  5. Wang, Yongyu

    1. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients
      Lorenz M. Jost, Hans-Peter Gschwind, Tarja Jalava, Yongyu Wang, Clemens Guenther, Claire Souppart, Antje Rottmann, Karsten Denner, Felix Waldmeier, Gerhard Gross, Eric Masson and Dirk Laurent
      Drug Metabolism and Disposition November 2006, 34 (11) 1817-1828; DOI: https://doi.org/10.1124/dmd.106.009944

  6. Warren, Chad J.

    1. Enzyme Source Effects on CYP2C9 Kinetics and Inhibition
      Vikas Kumar, Dan A. Rock, Chad J. Warren, Timothy S. Tracy and Jan L. Wahlstrom
      Drug Metabolism and Disposition November 2006, 34 (11) 1903-1908; DOI: https://doi.org/10.1124/dmd.106.010249

  7. Watanabe, Chizuru

    1. PDZ Adaptor Protein PDZK2 Stimulates Transport Activity of Organic Cation/Carnitine Transporter OCTN2 by Modulating Cell Surface Expression
      Chizuru Watanabe, Yukio Kato, Tomoko Sugiura, Yoshiyuki Kubo, Tomohiko Wakayama, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition November 2006, 34 (11) 1927-1934; DOI: https://doi.org/10.1124/dmd.106.010207

  8. Waters, Stephen

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

  9. Weems, Gary

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

  10. Weill, Sophie

    1. Pharmacokinetics, Metabolism, and Routes of Excretion of Intravenous Irofulven in Patients with Advanced Solid Tumors
      Angelo Paci, Keyvan Rezai, Alain Deroussent, Dominique De Valeriola, Micheline Re, Sophie Weill, Esteban Cvitkovic, Carmen Kahatt, Ajit Shah, Stephen Waters, Gary Weems, Gilles Vassal and François Lokiec
      Drug Metabolism and Disposition November 2006, 34 (11) 1918-1926; DOI: https://doi.org/10.1124/dmd.106.010512

  11. Wright, L. C.

    1. Human Metabolism of Nebicapone (BIA 3-202), a Novel Catechol-O-Methyltransferase Inhibitor: Characterization of in Vitro Glucuronidation
      A. I. Loureiro, M. J. Bonifácio, C. Fernandes-Lopes, L. Almeida, L. C. Wright and P. Soares-Da-Silva
      Drug Metabolism and Disposition November 2006, 34 (11) 1856-1862; DOI: https://doi.org/10.1124/dmd.106.010447

  12. Wu, Ellen Y.

    1. Identification of Enzymes Responsible for Primary and Sequential Oxygenation Reactions of Capravirine in Human Liver Microsomes
      Hai-Zhi Bu, Ping Zhao, Ping Kang, William F. Pool and Ellen Y. Wu
      Drug Metabolism and Disposition November 2006, 34 (11) 1798-1802; DOI: https://doi.org/10.1124/dmd.106.011189

Y

  1. Yamazaki, Hiroshi

    1. Rat Cytochrome P450 2C11 in Liver Microsomes Involved in Oxidation of Anesthetic Agent Propofol and Deactivated by Prior Treatment with Propofol
      Hiroshi Yamazaki, Makiko Shimizu, Takashi Nagashima, Masaki Minoshima and Norie Murayama
      Drug Metabolism and Disposition November 2006, 34 (11) 1803-1805; DOI: https://doi.org/10.1124/dmd.106.011627

  2. Ye, Yuyang

    1. Porcine Brain Microvessel Endothelial Cells as an in Vitro Model to Predict in Vivo Blood-Brain Barrier Permeability
      Yan Zhang, Cheryl S. W. Li, Yuyang Ye, Kjell Johnson, Julie Poe, Shannon Johnson, Walter Bobrowski, Rosario Garrido and Cherukury Madhu
      Drug Metabolism and Disposition November 2006, 34 (11) 1935-1943; DOI: https://doi.org/10.1124/dmd.105.006437

  3. Yoon, Yune-Jung

    1. Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
      Kwang-Hyeon Liu, Mi-Gyung Kim, Dong-Jun Lee, Yune-Jung Yoon, Min-Jung Kim, Ji-Hong Shon, Chang Soo Choi, Young Kil Choi, Zeuresenay Desta and Jae-Gook Shin
      Drug Metabolism and Disposition November 2006, 34 (11) 1793-1797; DOI: https://doi.org/10.1124/dmd.106.010488

  4. Yuasa, Hiroaki

    1. Molecular Identification and Functional Characterization of Rat Multidrug and Toxin Extrusion Type Transporter 1 as an Organic Cation/H+ Antiporter in the Kidney
      Kin-ya Ohta, Katsuhisa Inoue, Yayoi Hayashi and Hiroaki Yuasa
      Drug Metabolism and Disposition November 2006, 34 (11) 1868-1874; DOI: https://doi.org/10.1124/dmd.106.010876

Z

  1. Zhang, Yan

    1. Porcine Brain Microvessel Endothelial Cells as an in Vitro Model to Predict in Vivo Blood-Brain Barrier Permeability
      Yan Zhang, Cheryl S. W. Li, Yuyang Ye, Kjell Johnson, Julie Poe, Shannon Johnson, Walter Bobrowski, Rosario Garrido and Cherukury Madhu
      Drug Metabolism and Disposition November 2006, 34 (11) 1935-1943; DOI: https://doi.org/10.1124/dmd.105.006437

  2. Zhao, Ping

    1. Identification of Enzymes Responsible for Primary and Sequential Oxygenation Reactions of Capravirine in Human Liver Microsomes
      Hai-Zhi Bu, Ping Zhao, Ping Kang, William F. Pool and Ellen Y. Wu
      Drug Metabolism and Disposition November 2006, 34 (11) 1798-1802; DOI: https://doi.org/10.1124/dmd.106.011189
Back to top

In this issue

Advertisement