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Index by author

December 01, 2006; Volume 34,Issue 12

A

  1. Akao, Teruaki

    1. Pharmacokinetics of Berberine and Its Main Metabolites in Conventional and Pseudo Germ-Free Rats Determined by Liquid Chromatography/Ion Trap Mass Spectrometry
      Feng Zuo, Norio Nakamura, Teruaki Akao and Masao Hattori
      Drug Metabolism and Disposition December 2006, 34 (12) 2064-2072; DOI: https://doi.org/10.1124/dmd.106.011361

  2. Allen, James L.

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  3. Arvidsson, B.

    1. Characterization of Human Urinary Metabolites of the Antimalarial Piperaquine
      J. Tarning, Y. Bergqvist, N. P. Day, J. Bergquist, B. Arvidsson, N. J. White, M. Ashton and N. Lindegårdh
      Drug Metabolism and Disposition December 2006, 34 (12) 2011-2019; DOI: https://doi.org/10.1124/dmd.106.011494

  4. Ashton, M.

    1. Characterization of Human Urinary Metabolites of the Antimalarial Piperaquine
      J. Tarning, Y. Bergqvist, N. P. Day, J. Bergquist, B. Arvidsson, N. J. White, M. Ashton and N. Lindegårdh
      Drug Metabolism and Disposition December 2006, 34 (12) 2011-2019; DOI: https://doi.org/10.1124/dmd.106.011494

B

  1. Backman, Janne T.

    1. Rofecoxib Is a Potent, Metabolism-Dependent Inhibitor of CYP1A2: Implications for in Vitro Prediction of Drug Interactions
      Marjo J. Karjalainen, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition December 2006, 34 (12) 2091-2096; DOI: https://doi.org/10.1124/dmd.106.011965

  2. Bagnati, R.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

  3. Bahadduri, Praveen M.

    1. Rapid Identification of P-glycoprotein Substrates and Inhibitors
      Cheng Chang, Praveen M. Bahadduri, James E. Polli, Peter W. Swaan and Sean Ekins
      Drug Metabolism and Disposition December 2006, 34 (12) 1976-1984; DOI: https://doi.org/10.1124/dmd.106.012351

  4. Bergquist, J.

    1. Characterization of Human Urinary Metabolites of the Antimalarial Piperaquine
      J. Tarning, Y. Bergqvist, N. P. Day, J. Bergquist, B. Arvidsson, N. J. White, M. Ashton and N. Lindegårdh
      Drug Metabolism and Disposition December 2006, 34 (12) 2011-2019; DOI: https://doi.org/10.1124/dmd.106.011494

  5. Bergqvist, Y.

    1. Characterization of Human Urinary Metabolites of the Antimalarial Piperaquine
      J. Tarning, Y. Bergqvist, N. P. Day, J. Bergquist, B. Arvidsson, N. J. White, M. Ashton and N. Lindegårdh
      Drug Metabolism and Disposition December 2006, 34 (12) 2011-2019; DOI: https://doi.org/10.1124/dmd.106.011494

  6. Bertino, Joseph S.

    1. Drug-Metabolizing Enzyme Inhibition by Ketoconazole Does Not Reduce Interindividual Variability of CYP3A Activity as Measured by Oral Midazolam
      Maylee Chen, Anne N. Nafziger and Joseph S. Bertino
      Drug Metabolism and Disposition December 2006, 34 (12) 2079-2082; DOI: https://doi.org/10.1124/dmd.106.011742

  7. Bihorel, Sébastien

    1. Influence of Hydroxyurea On Imatinib Mesylate (Gleevec) Transport at the Mouse Blood-Brain Barrier
      Sébastien Bihorel, Gian Camenisch, Gerhard Gross, Michel Lemaire and Jean-Michel Scherrmann
      Drug Metabolism and Disposition December 2006, 34 (12) 1945-1949; DOI: https://doi.org/10.1124/dmd.106.010975

  8. Borbás, Tímea

    1. Investigation of Structure and Function of a Catalytically Efficient Variant of the Human Flavin-Containing Monooxygenase Form 3
      Tímea Borbás, Jun Zhang, Matt A. Cerny, István Likó and John R. Cashman
      Drug Metabolism and Disposition December 2006, 34 (12) 1995-2002; DOI: https://doi.org/10.1124/dmd.106.010827

  9. Boykin, David W.

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  10. Bridges, Arlene S.

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

C

  1. Camenisch, Gian

    1. Influence of Hydroxyurea On Imatinib Mesylate (Gleevec) Transport at the Mouse Blood-Brain Barrier
      Sébastien Bihorel, Gian Camenisch, Gerhard Gross, Michel Lemaire and Jean-Michel Scherrmann
      Drug Metabolism and Disposition December 2006, 34 (12) 1945-1949; DOI: https://doi.org/10.1124/dmd.106.010975

  2. Cashman, John R.

    1. Investigation of Structure and Function of a Catalytically Efficient Variant of the Human Flavin-Containing Monooxygenase Form 3
      Tímea Borbás, Jun Zhang, Matt A. Cerny, István Likó and John R. Cashman
      Drug Metabolism and Disposition December 2006, 34 (12) 1995-2002; DOI: https://doi.org/10.1124/dmd.106.010827

  3. Cerny, Matt A.

    1. Investigation of Structure and Function of a Catalytically Efficient Variant of the Human Flavin-Containing Monooxygenase Form 3
      Tímea Borbás, Jun Zhang, Matt A. Cerny, István Likó and John R. Cashman
      Drug Metabolism and Disposition December 2006, 34 (12) 1995-2002; DOI: https://doi.org/10.1124/dmd.106.010827

  4. Chang, Cheng

    1. Rapid Identification of P-glycoprotein Substrates and Inhibitors
      Cheng Chang, Praveen M. Bahadduri, James E. Polli, Peter W. Swaan and Sean Ekins
      Drug Metabolism and Disposition December 2006, 34 (12) 1976-1984; DOI: https://doi.org/10.1124/dmd.106.012351

  5. Chang, Jae H.

    1. The Role of P-glycoprotein in the Bioactivation of Raloxifene
      Jae H. Chang, Christopher J. Kochansky and Magang Shou
      Drug Metabolism and Disposition December 2006, 34 (12) 2073-2078; DOI: https://doi.org/10.1124/dmd.106.012179

  6. Chen, Maylee

    1. Drug-Metabolizing Enzyme Inhibition by Ketoconazole Does Not Reduce Interindividual Variability of CYP3A Activity as Measured by Oral Midazolam
      Maylee Chen, Anne N. Nafziger and Joseph S. Bertino
      Drug Metabolism and Disposition December 2006, 34 (12) 2079-2082; DOI: https://doi.org/10.1124/dmd.106.011742

  7. Cheung, Yen-Ling

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  8. Collins, Roxane

    1. Metabolic Aromatization of N-Alkyl-1,2,3,4-Tetrahydroquinoline Substructures to Quinolinium by Human Liver Microsomes and Horseradish Peroxidase
      Chungang Gu, Roxane Collins, Daniel D. Holsworth, Gregory S. Walker and Richard L. Voorman
      Drug Metabolism and Disposition December 2006, 34 (12) 2044-2055; DOI: https://doi.org/10.1124/dmd.106.012286

  9. Colombo, T.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

D

  1. D'Incalci, M.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

  2. Day, N. P.

    1. Characterization of Human Urinary Metabolites of the Antimalarial Piperaquine
      J. Tarning, Y. Bergqvist, N. P. Day, J. Bergquist, B. Arvidsson, N. J. White, M. Ashton and N. Lindegårdh
      Drug Metabolism and Disposition December 2006, 34 (12) 2011-2019; DOI: https://doi.org/10.1124/dmd.106.011494

  3. Dever, Joseph T.

    1. In Vivo Metabolism of l-Methionine in Mice: Evidence for Stereoselective Formation of Methionine-d-Sulfoxide and Quantitation of Other Major Metabolites
      Joseph T. Dever and Adnan A. Elfarra
      Drug Metabolism and Disposition December 2006, 34 (12) 2036-2043; DOI: https://doi.org/10.1124/dmd.106.012104

E

  1. Ekins, Sean

    1. Rapid Identification of P-glycoprotein Substrates and Inhibitors
      Cheng Chang, Praveen M. Bahadduri, James E. Polli, Peter W. Swaan and Sean Ekins
      Drug Metabolism and Disposition December 2006, 34 (12) 1976-1984; DOI: https://doi.org/10.1124/dmd.106.012351

  2. Elfarra, Adnan A.

    1. In Vivo Metabolism of l-Methionine in Mice: Evidence for Stereoselective Formation of Methionine-d-Sulfoxide and Quantitation of Other Major Metabolites
      Joseph T. Dever and Adnan A. Elfarra
      Drug Metabolism and Disposition December 2006, 34 (12) 2036-2043; DOI: https://doi.org/10.1124/dmd.106.012104

  3. Elliot, David J.

    1. Sulfinpyrazone C-Glucuronidation Is Catalyzed Selectively by Human UDP-Glucuronosyltransferase 1A9
      Oranun Kerdpin, David J. Elliot, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition December 2006, 34 (12) 1950-1953; DOI: https://doi.org/10.1124/dmd.106.012385

F

  1. Falcioni, C.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

  2. Ferguson, Stephen S.

    1. Phenytoin Induction of the Cyp2c37 Gene Is Mediated by the Constitutive Androstane Receptor
      Jonathan P. Jackson, Stephen S. Ferguson, Masahiko Negishi and Joyce A. Goldstein
      Drug Metabolism and Disposition December 2006, 34 (12) 2003-2010; DOI: https://doi.org/10.1124/dmd.106.012005

  3. Fontana, G.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

  4. Frapolli, R.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

G

  1. Ghanayem, Burhan I.

    1. Comparative Metabolism and Disposition of Trichloroethylene in Cyp2e1–/–and Wild-Type Mice
      Dojung Kim and Burhan I. Ghanayem
      Drug Metabolism and Disposition December 2006, 34 (12) 2020-2027; DOI: https://doi.org/10.1124/dmd.106.010538

  2. Goldstein, Joyce A.

    1. Phenytoin Induction of the Cyp2c37 Gene Is Mediated by the Constitutive Androstane Receptor
      Jonathan P. Jackson, Stephen S. Ferguson, Masahiko Negishi and Joyce A. Goldstein
      Drug Metabolism and Disposition December 2006, 34 (12) 2003-2010; DOI: https://doi.org/10.1124/dmd.106.012005

  3. Gorman, Lee A.

    1. CYP2C9 Inhibition: Impact of Probe Selection and Pharmacogenetics on in Vitro Inhibition Profiles
      Vikas Kumar, Jan L. Wahlstrom, Dan A. Rock, Chad J. Warren, Lee A. Gorman and Timothy S. Tracy
      Drug Metabolism and Disposition December 2006, 34 (12) 1966-1975; DOI: https://doi.org/10.1124/dmd.106.010926

  4. Gross, Gerhard

    1. Influence of Hydroxyurea On Imatinib Mesylate (Gleevec) Transport at the Mouse Blood-Brain Barrier
      Sébastien Bihorel, Gian Camenisch, Gerhard Gross, Michel Lemaire and Jean-Michel Scherrmann
      Drug Metabolism and Disposition December 2006, 34 (12) 1945-1949; DOI: https://doi.org/10.1124/dmd.106.010975

  5. Gu, Chungang

    1. Metabolic Aromatization of N-Alkyl-1,2,3,4-Tetrahydroquinoline Substructures to Quinolinium by Human Liver Microsomes and Horseradish Peroxidase
      Chungang Gu, Roxane Collins, Daniel D. Holsworth, Gregory S. Walker and Richard L. Voorman
      Drug Metabolism and Disposition December 2006, 34 (12) 2044-2055; DOI: https://doi.org/10.1124/dmd.106.012286

H

  1. Hall, James Edwin

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  2. Hall, Michael

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  3. Halpert, James R.

    1. Engineering of Cytochrome P450 3A4 for Enhanced Peroxide-Mediated Substrate Oxidation Using Directed Evolution and Site-Directed Mutagenesis
      Santosh Kumar, Hong Liu and James R. Halpert
      Drug Metabolism and Disposition December 2006, 34 (12) 1958-1965; DOI: https://doi.org/10.1124/dmd.106.012054

  4. Hattori, Masao

    1. Pharmacokinetics of Berberine and Its Main Metabolites in Conventional and Pseudo Germ-Free Rats Determined by Liquid Chromatography/Ion Trap Mass Spectrometry
      Feng Zuo, Norio Nakamura, Teruaki Akao and Masao Hattori
      Drug Metabolism and Disposition December 2006, 34 (12) 2064-2072; DOI: https://doi.org/10.1124/dmd.106.011361

  5. Hines, Ronald N.

    1. Epirubicin Glucuronidation and UGT2B7 Developmental Expression
      Matthew J. Zaya, Ronald N. Hines and Jeffrey C. Stevens
      Drug Metabolism and Disposition December 2006, 34 (12) 2097-2101; DOI: https://doi.org/10.1124/dmd.106.011387

  6. Hiramatsu, Remi

    1. Functional Analysis of Mouse and Monkey Multidrug Resistance-Associated Protein 2 (Mrp2)
      Mizuki Ninomiya, Kousei Ito, Remi Hiramatsu and Toshiharu Horie
      Drug Metabolism and Disposition December 2006, 34 (12) 2056-2063; DOI: https://doi.org/10.1124/dmd.106.010991

  7. Ho, Chi-Tang

    1. Peracetylation as a Means of Enhancing in Vitro Bioactivity and Bioavailability of Epigallocatechin-3-Gallate
      Joshua D. Lambert, Shengmin Sang, Jungil Hong, Seok-Joo Kwon, Mao-Jung Lee, Chi-Tang Ho and Chung S. Yang
      Drug Metabolism and Disposition December 2006, 34 (12) 2111-2116; DOI: https://doi.org/10.1124/dmd.106.011460

  8. Hoflack, Jean-Christophe

    1. Comparison of Coumarin-Induced Toxicity between Sandwich-Cultured Primary Rat Hepatocytes and Rats in Vivo: A Toxicogenomics Approach
      Anne S. Kienhuis, Heleen M. Wortelboer, Jean-Christophe Hoflack, Edwin J. Moonen, Jos C.S. Kleinjans, Ben van Ommen, Joost H. M. van Delft and Rob H. Stierum
      Drug Metabolism and Disposition December 2006, 34 (12) 2083-2090; DOI: https://doi.org/10.1124/dmd.106.011262

  9. Hollenberg, Paul F.

    1. Structure-Activity Relationship and Elucidation of the Determinant Factor(s) Responsible for the Mechanism-Based Inactivation of Cytochrome P450 2B6 by Substituted Phenyl Diaziridines
      Yoshimasa Kobayashi, Chitra Sridar, Ute M. Kent, Satish G. Puppali, John M. Rimoldi, Haoming Zhang, Lucy Waskell and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2006, 34 (12) 2102-2110; DOI: https://doi.org/10.1124/dmd.106.011452

  10. Holsworth, Daniel D.

    1. Metabolic Aromatization of N-Alkyl-1,2,3,4-Tetrahydroquinoline Substructures to Quinolinium by Human Liver Microsomes and Horseradish Peroxidase
      Chungang Gu, Roxane Collins, Daniel D. Holsworth, Gregory S. Walker and Richard L. Voorman
      Drug Metabolism and Disposition December 2006, 34 (12) 2044-2055; DOI: https://doi.org/10.1124/dmd.106.012286

  11. Hong, Jungil

    1. Peracetylation as a Means of Enhancing in Vitro Bioactivity and Bioavailability of Epigallocatechin-3-Gallate
      Joshua D. Lambert, Shengmin Sang, Jungil Hong, Seok-Joo Kwon, Mao-Jung Lee, Chi-Tang Ho and Chung S. Yang
      Drug Metabolism and Disposition December 2006, 34 (12) 2111-2116; DOI: https://doi.org/10.1124/dmd.106.011460

  12. Horie, Toshiharu

    1. Functional Analysis of Mouse and Monkey Multidrug Resistance-Associated Protein 2 (Mrp2)
      Mizuki Ninomiya, Kousei Ito, Remi Hiramatsu and Toshiharu Horie
      Drug Metabolism and Disposition December 2006, 34 (12) 2056-2063; DOI: https://doi.org/10.1124/dmd.106.010991

I

  1. Ito, Kousei

    1. Functional Analysis of Mouse and Monkey Multidrug Resistance-Associated Protein 2 (Mrp2)
      Mizuki Ninomiya, Kousei Ito, Remi Hiramatsu and Toshiharu Horie
      Drug Metabolism and Disposition December 2006, 34 (12) 2056-2063; DOI: https://doi.org/10.1124/dmd.106.010991

J

  1. Jackson, Jonathan P.

    1. Phenytoin Induction of the Cyp2c37 Gene Is Mediated by the Constitutive Androstane Receptor
      Jonathan P. Jackson, Stephen S. Ferguson, Masahiko Negishi and Joyce A. Goldstein
      Drug Metabolism and Disposition December 2006, 34 (12) 2003-2010; DOI: https://doi.org/10.1124/dmd.106.012005

K

  1. Karjalainen, Marjo J.

    1. Rofecoxib Is a Potent, Metabolism-Dependent Inhibitor of CYP1A2: Implications for in Vitro Prediction of Drug Interactions
      Marjo J. Karjalainen, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition December 2006, 34 (12) 2091-2096; DOI: https://doi.org/10.1124/dmd.106.011965

  2. Kent, Ute M.

    1. Structure-Activity Relationship and Elucidation of the Determinant Factor(s) Responsible for the Mechanism-Based Inactivation of Cytochrome P450 2B6 by Substituted Phenyl Diaziridines
      Yoshimasa Kobayashi, Chitra Sridar, Ute M. Kent, Satish G. Puppali, John M. Rimoldi, Haoming Zhang, Lucy Waskell and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2006, 34 (12) 2102-2110; DOI: https://doi.org/10.1124/dmd.106.011452

  3. Kerdpin, Oranun

    1. Sulfinpyrazone C-Glucuronidation Is Catalyzed Selectively by Human UDP-Glucuronosyltransferase 1A9
      Oranun Kerdpin, David J. Elliot, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition December 2006, 34 (12) 1950-1953; DOI: https://doi.org/10.1124/dmd.106.012385

  4. Kienhuis, Anne S.

    1. Comparison of Coumarin-Induced Toxicity between Sandwich-Cultured Primary Rat Hepatocytes and Rats in Vivo: A Toxicogenomics Approach
      Anne S. Kienhuis, Heleen M. Wortelboer, Jean-Christophe Hoflack, Edwin J. Moonen, Jos C.S. Kleinjans, Ben van Ommen, Joost H. M. van Delft and Rob H. Stierum
      Drug Metabolism and Disposition December 2006, 34 (12) 2083-2090; DOI: https://doi.org/10.1124/dmd.106.011262

  5. Kim, Dojung

    1. Comparative Metabolism and Disposition of Trichloroethylene in Cyp2e1–/–and Wild-Type Mice
      Dojung Kim and Burhan I. Ghanayem
      Drug Metabolism and Disposition December 2006, 34 (12) 2020-2027; DOI: https://doi.org/10.1124/dmd.106.010538

  6. Kleinjans, Jos C.S.

    1. Comparison of Coumarin-Induced Toxicity between Sandwich-Cultured Primary Rat Hepatocytes and Rats in Vivo: A Toxicogenomics Approach
      Anne S. Kienhuis, Heleen M. Wortelboer, Jean-Christophe Hoflack, Edwin J. Moonen, Jos C.S. Kleinjans, Ben van Ommen, Joost H. M. van Delft and Rob H. Stierum
      Drug Metabolism and Disposition December 2006, 34 (12) 2083-2090; DOI: https://doi.org/10.1124/dmd.106.011262

  7. Kobayashi, Yoshimasa

    1. Structure-Activity Relationship and Elucidation of the Determinant Factor(s) Responsible for the Mechanism-Based Inactivation of Cytochrome P450 2B6 by Substituted Phenyl Diaziridines
      Yoshimasa Kobayashi, Chitra Sridar, Ute M. Kent, Satish G. Puppali, John M. Rimoldi, Haoming Zhang, Lucy Waskell and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2006, 34 (12) 2102-2110; DOI: https://doi.org/10.1124/dmd.106.011452

  8. Kochansky, Christopher J.

    1. The Role of P-glycoprotein in the Bioactivation of Raloxifene
      Jae H. Chang, Christopher J. Kochansky and Magang Shou
      Drug Metabolism and Disposition December 2006, 34 (12) 2073-2078; DOI: https://doi.org/10.1124/dmd.106.012179

  9. Kumar, Santosh

    1. Engineering of Cytochrome P450 3A4 for Enhanced Peroxide-Mediated Substrate Oxidation Using Directed Evolution and Site-Directed Mutagenesis
      Santosh Kumar, Hong Liu and James R. Halpert
      Drug Metabolism and Disposition December 2006, 34 (12) 1958-1965; DOI: https://doi.org/10.1124/dmd.106.012054

  10. Kumar, Vikas

    1. CYP2C9 Inhibition: Impact of Probe Selection and Pharmacogenetics on in Vitro Inhibition Profiles
      Vikas Kumar, Jan L. Wahlstrom, Dan A. Rock, Chad J. Warren, Lee A. Gorman and Timothy S. Tracy
      Drug Metabolism and Disposition December 2006, 34 (12) 1966-1975; DOI: https://doi.org/10.1124/dmd.106.010926

  11. Kwon, Seok-Joo

    1. Peracetylation as a Means of Enhancing in Vitro Bioactivity and Bioavailability of Epigallocatechin-3-Gallate
      Joshua D. Lambert, Shengmin Sang, Jungil Hong, Seok-Joo Kwon, Mao-Jung Lee, Chi-Tang Ho and Chung S. Yang
      Drug Metabolism and Disposition December 2006, 34 (12) 2111-2116; DOI: https://doi.org/10.1124/dmd.106.011460

L

  1. Lambert, Joshua D.

    1. Peracetylation as a Means of Enhancing in Vitro Bioactivity and Bioavailability of Epigallocatechin-3-Gallate
      Joshua D. Lambert, Shengmin Sang, Jungil Hong, Seok-Joo Kwon, Mao-Jung Lee, Chi-Tang Ho and Chung S. Yang
      Drug Metabolism and Disposition December 2006, 34 (12) 2111-2116; DOI: https://doi.org/10.1124/dmd.106.011460

  2. Lee, Mao-Jung

    1. Peracetylation as a Means of Enhancing in Vitro Bioactivity and Bioavailability of Epigallocatechin-3-Gallate
      Joshua D. Lambert, Shengmin Sang, Jungil Hong, Seok-Joo Kwon, Mao-Jung Lee, Chi-Tang Ho and Chung S. Yang
      Drug Metabolism and Disposition December 2006, 34 (12) 2111-2116; DOI: https://doi.org/10.1124/dmd.106.011460

  3. Lemaire, Michel

    1. Influence of Hydroxyurea On Imatinib Mesylate (Gleevec) Transport at the Mouse Blood-Brain Barrier
      Sébastien Bihorel, Gian Camenisch, Gerhard Gross, Michel Lemaire and Jean-Michel Scherrmann
      Drug Metabolism and Disposition December 2006, 34 (12) 1945-1949; DOI: https://doi.org/10.1124/dmd.106.010975

  4. Likó, István

    1. Investigation of Structure and Function of a Catalytically Efficient Variant of the Human Flavin-Containing Monooxygenase Form 3
      Tímea Borbás, Jun Zhang, Matt A. Cerny, István Likó and John R. Cashman
      Drug Metabolism and Disposition December 2006, 34 (12) 1995-2002; DOI: https://doi.org/10.1124/dmd.106.010827

  5. Lindegårdh, N.

    1. Characterization of Human Urinary Metabolites of the Antimalarial Piperaquine
      J. Tarning, Y. Bergqvist, N. P. Day, J. Bergquist, B. Arvidsson, N. J. White, M. Ashton and N. Lindegårdh
      Drug Metabolism and Disposition December 2006, 34 (12) 2011-2019; DOI: https://doi.org/10.1124/dmd.106.011494

  6. Liu, Hong

    1. Engineering of Cytochrome P450 3A4 for Enhanced Peroxide-Mediated Substrate Oxidation Using Directed Evolution and Site-Directed Mutagenesis
      Santosh Kumar, Hong Liu and James R. Halpert
      Drug Metabolism and Disposition December 2006, 34 (12) 1958-1965; DOI: https://doi.org/10.1124/dmd.106.012054

  7. Locuson, Charles W.

    1. Identification of Binding Sites of Non-I-Helix Water Molecules in Mammalian Cytochromes P450
      Charles W. Locuson and Timothy S. Tracy
      Drug Metabolism and Disposition December 2006, 34 (12) 1954-1957; DOI: https://doi.org/10.1124/dmd.106.011890

  8. Loewen, Greg

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

M

  1. Mackenzie, Peter I.

    1. Sulfinpyrazone C-Glucuronidation Is Catalyzed Selectively by Human UDP-Glucuronosyltransferase 1A9
      Oranun Kerdpin, David J. Elliot, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition December 2006, 34 (12) 1950-1953; DOI: https://doi.org/10.1124/dmd.106.012385

  2. Manzotti, C.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

  3. Marangon, E.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

  4. Miners, John O.

    1. Sulfinpyrazone C-Glucuronidation Is Catalyzed Selectively by Human UDP-Glucuronosyltransferase 1A9
      Oranun Kerdpin, David J. Elliot, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition December 2006, 34 (12) 1950-1953; DOI: https://doi.org/10.1124/dmd.106.012385

  5. Moonen, Edwin J.

    1. Comparison of Coumarin-Induced Toxicity between Sandwich-Cultured Primary Rat Hepatocytes and Rats in Vivo: A Toxicogenomics Approach
      Anne S. Kienhuis, Heleen M. Wortelboer, Jean-Christophe Hoflack, Edwin J. Moonen, Jos C.S. Kleinjans, Ben van Ommen, Joost H. M. van Delft and Rob H. Stierum
      Drug Metabolism and Disposition December 2006, 34 (12) 2083-2090; DOI: https://doi.org/10.1124/dmd.106.011262

  6. Morazzoni, P.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

N

  1. Nafziger, Anne N.

    1. Drug-Metabolizing Enzyme Inhibition by Ketoconazole Does Not Reduce Interindividual Variability of CYP3A Activity as Measured by Oral Midazolam
      Maylee Chen, Anne N. Nafziger and Joseph S. Bertino
      Drug Metabolism and Disposition December 2006, 34 (12) 2079-2082; DOI: https://doi.org/10.1124/dmd.106.011742

  2. Nakamura, Norio

    1. Pharmacokinetics of Berberine and Its Main Metabolites in Conventional and Pseudo Germ-Free Rats Determined by Liquid Chromatography/Ion Trap Mass Spectrometry
      Feng Zuo, Norio Nakamura, Teruaki Akao and Masao Hattori
      Drug Metabolism and Disposition December 2006, 34 (12) 2064-2072; DOI: https://doi.org/10.1124/dmd.106.011361

  3. Negishi, Masahiko

    1. Phenytoin Induction of the Cyp2c37 Gene Is Mediated by the Constitutive Androstane Receptor
      Jonathan P. Jackson, Stephen S. Ferguson, Masahiko Negishi and Joyce A. Goldstein
      Drug Metabolism and Disposition December 2006, 34 (12) 2003-2010; DOI: https://doi.org/10.1124/dmd.106.012005

  4. Neuvonen, Pertti J.

    1. Rofecoxib Is a Potent, Metabolism-Dependent Inhibitor of CYP1A2: Implications for in Vitro Prediction of Drug Interactions
      Marjo J. Karjalainen, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition December 2006, 34 (12) 2091-2096; DOI: https://doi.org/10.1124/dmd.106.011965

  5. Ninomiya, Mizuki

    1. Functional Analysis of Mouse and Monkey Multidrug Resistance-Associated Protein 2 (Mrp2)
      Mizuki Ninomiya, Kousei Ito, Remi Hiramatsu and Toshiharu Horie
      Drug Metabolism and Disposition December 2006, 34 (12) 2056-2063; DOI: https://doi.org/10.1124/dmd.106.010991

P

  1. Paine, Mary F.

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  2. Parkinson, Andrew

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  3. Parkinson, Oliver T.

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  4. Polli, James E.

    1. Rapid Identification of P-glycoprotein Substrates and Inhibitors
      Cheng Chang, Praveen M. Bahadduri, James E. Polli, Peter W. Swaan and Sean Ekins
      Drug Metabolism and Disposition December 2006, 34 (12) 1976-1984; DOI: https://doi.org/10.1124/dmd.106.012351

  5. Puppali, Satish G.

    1. Structure-Activity Relationship and Elucidation of the Determinant Factor(s) Responsible for the Mechanism-Based Inactivation of Cytochrome P450 2B6 by Substituted Phenyl Diaziridines
      Yoshimasa Kobayashi, Chitra Sridar, Ute M. Kent, Satish G. Puppali, John M. Rimoldi, Haoming Zhang, Lucy Waskell and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2006, 34 (12) 2102-2110; DOI: https://doi.org/10.1124/dmd.106.011452

R

  1. Rimoldi, John M.

    1. Structure-Activity Relationship and Elucidation of the Determinant Factor(s) Responsible for the Mechanism-Based Inactivation of Cytochrome P450 2B6 by Substituted Phenyl Diaziridines
      Yoshimasa Kobayashi, Chitra Sridar, Ute M. Kent, Satish G. Puppali, John M. Rimoldi, Haoming Zhang, Lucy Waskell and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2006, 34 (12) 2102-2110; DOI: https://doi.org/10.1124/dmd.106.011452

  2. Rock, Dan A.

    1. CYP2C9 Inhibition: Impact of Probe Selection and Pharmacogenetics on in Vitro Inhibition Profiles
      Vikas Kumar, Jan L. Wahlstrom, Dan A. Rock, Chad J. Warren, Lee A. Gorman and Timothy S. Tracy
      Drug Metabolism and Disposition December 2006, 34 (12) 1966-1975; DOI: https://doi.org/10.1124/dmd.106.010926

S

  1. Sang, Shengmin

    1. Peracetylation as a Means of Enhancing in Vitro Bioactivity and Bioavailability of Epigallocatechin-3-Gallate
      Joshua D. Lambert, Shengmin Sang, Jungil Hong, Seok-Joo Kwon, Mao-Jung Lee, Chi-Tang Ho and Chung S. Yang
      Drug Metabolism and Disposition December 2006, 34 (12) 2111-2116; DOI: https://doi.org/10.1124/dmd.106.011460

  2. Saulter, Janelle Y.

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  3. Scherrmann, Jean-Michel

    1. Influence of Hydroxyurea On Imatinib Mesylate (Gleevec) Transport at the Mouse Blood-Brain Barrier
      Sébastien Bihorel, Gian Camenisch, Gerhard Gross, Michel Lemaire and Jean-Michel Scherrmann
      Drug Metabolism and Disposition December 2006, 34 (12) 1945-1949; DOI: https://doi.org/10.1124/dmd.106.010975

  4. Shou, Magang

    1. The Role of P-glycoprotein in the Bioactivation of Raloxifene
      Jae H. Chang, Christopher J. Kochansky and Magang Shou
      Drug Metabolism and Disposition December 2006, 34 (12) 2073-2078; DOI: https://doi.org/10.1124/dmd.106.012179

  5. Simone, M.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

  6. Sridar, Chitra

    1. Structure-Activity Relationship and Elucidation of the Determinant Factor(s) Responsible for the Mechanism-Based Inactivation of Cytochrome P450 2B6 by Substituted Phenyl Diaziridines
      Yoshimasa Kobayashi, Chitra Sridar, Ute M. Kent, Satish G. Puppali, John M. Rimoldi, Haoming Zhang, Lucy Waskell and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2006, 34 (12) 2102-2110; DOI: https://doi.org/10.1124/dmd.106.011452

  7. Stephens, Chad E.

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  8. Stevens, Jeffrey C.

    1. Epirubicin Glucuronidation and UGT2B7 Developmental Expression
      Matthew J. Zaya, Ronald N. Hines and Jeffrey C. Stevens
      Drug Metabolism and Disposition December 2006, 34 (12) 2097-2101; DOI: https://doi.org/10.1124/dmd.106.011387

  9. Stierum, Rob H.

    1. Comparison of Coumarin-Induced Toxicity between Sandwich-Cultured Primary Rat Hepatocytes and Rats in Vivo: A Toxicogenomics Approach
      Anne S. Kienhuis, Heleen M. Wortelboer, Jean-Christophe Hoflack, Edwin J. Moonen, Jos C.S. Kleinjans, Ben van Ommen, Joost H. M. van Delft and Rob H. Stierum
      Drug Metabolism and Disposition December 2006, 34 (12) 2083-2090; DOI: https://doi.org/10.1124/dmd.106.011262

  10. Swaan, Peter W.

    1. Rapid Identification of P-glycoprotein Substrates and Inhibitors
      Cheng Chang, Praveen M. Bahadduri, James E. Polli, Peter W. Swaan and Sean Ekins
      Drug Metabolism and Disposition December 2006, 34 (12) 1976-1984; DOI: https://doi.org/10.1124/dmd.106.012351

T

  1. Tarning, J.

    1. Characterization of Human Urinary Metabolites of the Antimalarial Piperaquine
      J. Tarning, Y. Bergqvist, N. P. Day, J. Bergquist, B. Arvidsson, N. J. White, M. Ashton and N. Lindegårdh
      Drug Metabolism and Disposition December 2006, 34 (12) 2011-2019; DOI: https://doi.org/10.1124/dmd.106.011494

  2. Tidwell, Richard R.

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  3. Tracy, Timothy S.

    1. Identification of Binding Sites of Non-I-Helix Water Molecules in Mammalian Cytochromes P450
      Charles W. Locuson and Timothy S. Tracy
      Drug Metabolism and Disposition December 2006, 34 (12) 1954-1957; DOI: https://doi.org/10.1124/dmd.106.011890
    2. CYP2C9 Inhibition: Impact of Probe Selection and Pharmacogenetics on in Vitro Inhibition Profiles
      Vikas Kumar, Jan L. Wahlstrom, Dan A. Rock, Chad J. Warren, Lee A. Gorman and Timothy S. Tracy
      Drug Metabolism and Disposition December 2006, 34 (12) 1966-1975; DOI: https://doi.org/10.1124/dmd.106.010926

U

  1. Usuki, Etsuko

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

V

  1. van Delft, Joost H. M.

    1. Comparison of Coumarin-Induced Toxicity between Sandwich-Cultured Primary Rat Hepatocytes and Rats in Vivo: A Toxicogenomics Approach
      Anne S. Kienhuis, Heleen M. Wortelboer, Jean-Christophe Hoflack, Edwin J. Moonen, Jos C.S. Kleinjans, Ben van Ommen, Joost H. M. van Delft and Rob H. Stierum
      Drug Metabolism and Disposition December 2006, 34 (12) 2083-2090; DOI: https://doi.org/10.1124/dmd.106.011262

  2. van Ommen, Ben

    1. Comparison of Coumarin-Induced Toxicity between Sandwich-Cultured Primary Rat Hepatocytes and Rats in Vivo: A Toxicogenomics Approach
      Anne S. Kienhuis, Heleen M. Wortelboer, Jean-Christophe Hoflack, Edwin J. Moonen, Jos C.S. Kleinjans, Ben van Ommen, Joost H. M. van Delft and Rob H. Stierum
      Drug Metabolism and Disposition December 2006, 34 (12) 2083-2090; DOI: https://doi.org/10.1124/dmd.106.011262

  3. Voorman, Richard L.

    1. Metabolic Aromatization of N-Alkyl-1,2,3,4-Tetrahydroquinoline Substructures to Quinolinium by Human Liver Microsomes and Horseradish Peroxidase
      Chungang Gu, Roxane Collins, Daniel D. Holsworth, Gregory S. Walker and Richard L. Voorman
      Drug Metabolism and Disposition December 2006, 34 (12) 2044-2055; DOI: https://doi.org/10.1124/dmd.106.012286

W

  1. Wahlstrom, Jan L.

    1. CYP2C9 Inhibition: Impact of Probe Selection and Pharmacogenetics on in Vitro Inhibition Profiles
      Vikas Kumar, Jan L. Wahlstrom, Dan A. Rock, Chad J. Warren, Lee A. Gorman and Timothy S. Tracy
      Drug Metabolism and Disposition December 2006, 34 (12) 1966-1975; DOI: https://doi.org/10.1124/dmd.106.010926

  2. Walker, Gregory S.

    1. Metabolic Aromatization of N-Alkyl-1,2,3,4-Tetrahydroquinoline Substructures to Quinolinium by Human Liver Microsomes and Horseradish Peroxidase
      Chungang Gu, Roxane Collins, Daniel D. Holsworth, Gregory S. Walker and Richard L. Voorman
      Drug Metabolism and Disposition December 2006, 34 (12) 2044-2055; DOI: https://doi.org/10.1124/dmd.106.012286

  3. Wang, Michael Zhuo

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  4. Warren, Chad J.

    1. CYP2C9 Inhibition: Impact of Probe Selection and Pharmacogenetics on in Vitro Inhibition Profiles
      Vikas Kumar, Jan L. Wahlstrom, Dan A. Rock, Chad J. Warren, Lee A. Gorman and Timothy S. Tracy
      Drug Metabolism and Disposition December 2006, 34 (12) 1966-1975; DOI: https://doi.org/10.1124/dmd.106.010926

  5. Waskell, Lucy

    1. Structure-Activity Relationship and Elucidation of the Determinant Factor(s) Responsible for the Mechanism-Based Inactivation of Cytochrome P450 2B6 by Substituted Phenyl Diaziridines
      Yoshimasa Kobayashi, Chitra Sridar, Ute M. Kent, Satish G. Puppali, John M. Rimoldi, Haoming Zhang, Lucy Waskell and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2006, 34 (12) 2102-2110; DOI: https://doi.org/10.1124/dmd.106.011452

  6. White, N. J.

    1. Characterization of Human Urinary Metabolites of the Antimalarial Piperaquine
      J. Tarning, Y. Bergqvist, N. P. Day, J. Bergquist, B. Arvidsson, N. J. White, M. Ashton and N. Lindegårdh
      Drug Metabolism and Disposition December 2006, 34 (12) 2011-2019; DOI: https://doi.org/10.1124/dmd.106.011494

  7. Wortelboer, Heleen M.

    1. Comparison of Coumarin-Induced Toxicity between Sandwich-Cultured Primary Rat Hepatocytes and Rats in Vivo: A Toxicogenomics Approach
      Anne S. Kienhuis, Heleen M. Wortelboer, Jean-Christophe Hoflack, Edwin J. Moonen, Jos C.S. Kleinjans, Ben van Ommen, Joost H. M. van Delft and Rob H. Stierum
      Drug Metabolism and Disposition December 2006, 34 (12) 2083-2090; DOI: https://doi.org/10.1124/dmd.106.011262

Y

  1. Yang, Chung S.

    1. Peracetylation as a Means of Enhancing in Vitro Bioactivity and Bioavailability of Epigallocatechin-3-Gallate
      Joshua D. Lambert, Shengmin Sang, Jungil Hong, Seok-Joo Kwon, Mao-Jung Lee, Chi-Tang Ho and Chung S. Yang
      Drug Metabolism and Disposition December 2006, 34 (12) 2111-2116; DOI: https://doi.org/10.1124/dmd.106.011460

Z

  1. Zaffaroni, M.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

  2. Zaya, Matthew J.

    1. Epirubicin Glucuronidation and UGT2B7 Developmental Expression
      Matthew J. Zaya, Ronald N. Hines and Jeffrey C. Stevens
      Drug Metabolism and Disposition December 2006, 34 (12) 2097-2101; DOI: https://doi.org/10.1124/dmd.106.011387

  3. Zeldin, Darryl C.

    1. CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
      Michael Zhuo Wang, Janelle Y. Saulter, Etsuko Usuki, Yen-Ling Cheung, Michael Hall, Arlene S. Bridges, Greg Loewen, Oliver T. Parkinson, Chad E. Stephens, James L. Allen, Darryl C. Zeldin, David W. Boykin, Richard R. Tidwell, Andrew Parkinson, Mary F. Paine and James Edwin Hall
      Drug Metabolism and Disposition December 2006, 34 (12) 1985-1994; DOI: https://doi.org/10.1124/dmd.106.010587

  4. Zhang, Haoming

    1. Structure-Activity Relationship and Elucidation of the Determinant Factor(s) Responsible for the Mechanism-Based Inactivation of Cytochrome P450 2B6 by Substituted Phenyl Diaziridines
      Yoshimasa Kobayashi, Chitra Sridar, Ute M. Kent, Satish G. Puppali, John M. Rimoldi, Haoming Zhang, Lucy Waskell and Paul F. Hollenberg
      Drug Metabolism and Disposition December 2006, 34 (12) 2102-2110; DOI: https://doi.org/10.1124/dmd.106.011452

  5. Zhang, Jun

    1. Investigation of Structure and Function of a Catalytically Efficient Variant of the Human Flavin-Containing Monooxygenase Form 3
      Tímea Borbás, Jun Zhang, Matt A. Cerny, István Likó and John R. Cashman
      Drug Metabolism and Disposition December 2006, 34 (12) 1995-2002; DOI: https://doi.org/10.1124/dmd.106.010827

  6. Zucchetti, M.

    1. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
      R. Frapolli, E. Marangon, M. Zaffaroni, T. Colombo, C. Falcioni, R. Bagnati, M. Simone, M. D'Incalci, C. Manzotti, G. Fontana, P. Morazzoni and M. Zucchetti
      Drug Metabolism and Disposition December 2006, 34 (12) 2028-2035; DOI: https://doi.org/10.1124/dmd.106.012153

  7. Zuo, Feng

    1. Pharmacokinetics of Berberine and Its Main Metabolites in Conventional and Pseudo Germ-Free Rats Determined by Liquid Chromatography/Ion Trap Mass Spectrometry
      Feng Zuo, Norio Nakamura, Teruaki Akao and Masao Hattori
      Drug Metabolism and Disposition December 2006, 34 (12) 2064-2072; DOI: https://doi.org/10.1124/dmd.106.011361
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