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Drug Metabolism & Disposition

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Index by author

February 01, 2006; Volume 34,Issue 2
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Acott, Philip D.

    1. You have access
      BRAIN CYCLOSPORIN A LEVELS ARE DETERMINED BY ONTOGENIC REGULATION OF MDR1A EXPRESSION
      Kerry B. Goralski, Philip D. Acott, Albert D. Fraser, David Worth and Christopher J. Sinal
      Drug Metabolism and Disposition February 2006, 34 (2) 288-295; DOI: https://doi.org/10.1124/dmd.105.007427
  2. Aranibar, Nelly

    1. You have access
      STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
      Donglu Zhang, Haiying Zhang, Nelly Aranibar, Ronald Hanson, Yande Huang, Peter T. Cheng, Shung Wu, Samuel Bonacorsi, Mingshe Zhu, Arun Swaminathan and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2006, 34 (2) 267-280; DOI: https://doi.org/10.1124/dmd.105.007153

B

  1. Barbuch, Robert J.

    1. You have access
      IN VIVO METABOLISM OF [14C]RUBOXISTAURIN IN DOGS, MICE, AND RATS FOLLOWING ORAL ADMINISTRATION AND THE STRUCTURE DETERMINATION OF ITS METABOLITES BY LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY AND NMR SPECTROSCOPY
      Robert J. Barbuch, Kristina Campanale, Chad E. Hadden, Milton Zmijewski, Ping Yi, Douglas D. O'Bannon, Jennifer L. Burkey and Palaniappan Kulanthaivel
      Drug Metabolism and Disposition February 2006, 34 (2) 213-224; DOI: https://doi.org/10.1124/dmd.105.007401
  2. Bigler, Jeannette

    1. You have access
      GLUCURONIDATION OF THE ASPIRIN METABOLITE SALICYLIC ACID BY EXPRESSED UDP-GLUCURONOSYLTRANSFERASES AND HUMAN LIVER MICROSOMES
      Gwendolyn E. Kuehl, Jeannette Bigler, John D. Potter and Johanna W. Lampe
      Drug Metabolism and Disposition February 2006, 34 (2) 199-202; DOI: https://doi.org/10.1124/dmd.105.005652
  3. Bohl, Casey E.

    1. You have access
      CHARACTERIZATION OF THE IN VITRO METABOLISM OF SELECTIVE ANDROGEN RECEPTOR MODULATOR USING HUMAN, RAT, AND DOG LIVER ENZYME PREPARATIONS
      Wenqing Gao, Zengru Wu, Casey E. Bohl, Jun Yang, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition February 2006, 34 (2) 243-253; DOI: https://doi.org/10.1124/dmd.105.007112
  4. Bonacorsi, Samuel

    1. You have access
      STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
      Donglu Zhang, Haiying Zhang, Nelly Aranibar, Ronald Hanson, Yande Huang, Peter T. Cheng, Shung Wu, Samuel Bonacorsi, Mingshe Zhu, Arun Swaminathan and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2006, 34 (2) 267-280; DOI: https://doi.org/10.1124/dmd.105.007153
  5. Brogan, Leonie R.

    1. You have access
      ROLE OF MRP2 IN THE HEPATIC DISPOSITION OF MYCOPHENOLIC ACID AND ITS GLUCURONIDE METABOLITES: EFFECT OF CYCLOSPORINE
      Ian S. Westley, Leonie R. Brogan, Raymond G. Morris, Allan M. Evans and Benedetta C. Sallustio
      Drug Metabolism and Disposition February 2006, 34 (2) 261-266; DOI: https://doi.org/10.1124/dmd.105.006122
  6. Brown, S. A.

    1. You have access
      DEVELOPMENT OF NOVEL FURANOCOUMARIN DIMERS AS POTENT AND SELECTIVE INHIBITORS OF CYP3A4
      E. Row, S. A. Brown, A. V. Stachulski and M. S. Lennard
      Drug Metabolism and Disposition February 2006, 34 (2) 324-330; DOI: https://doi.org/10.1124/dmd.105.007294
  7. Burkey, Jennifer L.

    1. You have access
      IN VIVO METABOLISM OF [14C]RUBOXISTAURIN IN DOGS, MICE, AND RATS FOLLOWING ORAL ADMINISTRATION AND THE STRUCTURE DETERMINATION OF ITS METABOLITES BY LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY AND NMR SPECTROSCOPY
      Robert J. Barbuch, Kristina Campanale, Chad E. Hadden, Milton Zmijewski, Ping Yi, Douglas D. O'Bannon, Jennifer L. Burkey and Palaniappan Kulanthaivel
      Drug Metabolism and Disposition February 2006, 34 (2) 213-224; DOI: https://doi.org/10.1124/dmd.105.007401
  8. Buzdar, Aman U.

    1. You have access
      DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR
      Hidetoshi Yamaya, Mayuko Saeki, Ken-ichiro Yoshida, Jiro Shibata, Shingo Yano, Yoshiaki Sato, Atsushi Takao, Takashi Shindo, Aman U. Buzdar and Sekio Nagayama
      Drug Metabolism and Disposition February 2006, 34 (2) 331-338; DOI: https://doi.org/10.1124/dmd.105.005504

C

  1. Campanale, Kristina

    1. You have access
      IN VIVO METABOLISM OF [14C]RUBOXISTAURIN IN DOGS, MICE, AND RATS FOLLOWING ORAL ADMINISTRATION AND THE STRUCTURE DETERMINATION OF ITS METABOLITES BY LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY AND NMR SPECTROSCOPY
      Robert J. Barbuch, Kristina Campanale, Chad E. Hadden, Milton Zmijewski, Ping Yi, Douglas D. O'Bannon, Jennifer L. Burkey and Palaniappan Kulanthaivel
      Drug Metabolism and Disposition February 2006, 34 (2) 213-224; DOI: https://doi.org/10.1124/dmd.105.007401
  2. Chang, Thomas K. H.

    1. You have access
      DISTINCT ROLE OF BILOBALIDE AND GINKGOLIDE A IN THE MODULATION OF RAT CYP2B1 AND CYP3A23 GENE EXPRESSION BY GINKGO BILOBA EXTRACT IN CULTURED HEPATOCYTES
      Thomas K. H. Chang, Jie Chen and Xiao Wei Teng
      Drug Metabolism and Disposition February 2006, 34 (2) 234-242; DOI: https://doi.org/10.1124/dmd.105.005751
  3. Chao, Pei-Dawn Lee

    1. You have access
      INHIBITION OF LUNG CANCER CELL GROWTH BY QUERCETIN GLUCURONIDES VIA G2/M ARREST AND INDUCTION OF APOPTOSIS
      Jen-Hung Yang, Te-Chun Hsia, Hsiu-Maan Kuo, Pei-Dawn Lee Chao, Chi-Chung Chou, Yau-Huei Wei and Jing-Gung Chung
      Drug Metabolism and Disposition February 2006, 34 (2) 296-304; DOI: https://doi.org/10.1124/dmd.105.005280
  4. Chatelain, Pierre

    1. You have access
      BRAIN DISTRIBUTION OF CETIRIZINE ENANTIOMERS: COMPARISON OF THREE DIFFERENT TISSUE-TO-PLASMA PARTITION COEFFICIENTS: Kp, Kp,u, AND Kp,uu
      Anubha Gupta, Pierre Chatelain, Roy Massingham, E. Niclas Jonsson and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition February 2006, 34 (2) 318-323; DOI: https://doi.org/10.1124/dmd.105.007211
  5. Chen, Jie

    1. You have access
      DISTINCT ROLE OF BILOBALIDE AND GINKGOLIDE A IN THE MODULATION OF RAT CYP2B1 AND CYP3A23 GENE EXPRESSION BY GINKGO BILOBA EXTRACT IN CULTURED HEPATOCYTES
      Thomas K. H. Chang, Jie Chen and Xiao Wei Teng
      Drug Metabolism and Disposition February 2006, 34 (2) 234-242; DOI: https://doi.org/10.1124/dmd.105.005751
  6. Cheng, Peter T.

    1. You have access
      STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
      Donglu Zhang, Haiying Zhang, Nelly Aranibar, Ronald Hanson, Yande Huang, Peter T. Cheng, Shung Wu, Samuel Bonacorsi, Mingshe Zhu, Arun Swaminathan and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2006, 34 (2) 267-280; DOI: https://doi.org/10.1124/dmd.105.007153
  7. Chou, Chi-Chung

    1. You have access
      INHIBITION OF LUNG CANCER CELL GROWTH BY QUERCETIN GLUCURONIDES VIA G2/M ARREST AND INDUCTION OF APOPTOSIS
      Jen-Hung Yang, Te-Chun Hsia, Hsiu-Maan Kuo, Pei-Dawn Lee Chao, Chi-Chung Chou, Yau-Huei Wei and Jing-Gung Chung
      Drug Metabolism and Disposition February 2006, 34 (2) 296-304; DOI: https://doi.org/10.1124/dmd.105.005280
  8. Chung, Jing-Gung

    1. You have access
      INHIBITION OF LUNG CANCER CELL GROWTH BY QUERCETIN GLUCURONIDES VIA G2/M ARREST AND INDUCTION OF APOPTOSIS
      Jen-Hung Yang, Te-Chun Hsia, Hsiu-Maan Kuo, Pei-Dawn Lee Chao, Chi-Chung Chou, Yau-Huei Wei and Jing-Gung Chung
      Drug Metabolism and Disposition February 2006, 34 (2) 296-304; DOI: https://doi.org/10.1124/dmd.105.005280

D

  1. Dalton, James T.

    1. You have access
      CHARACTERIZATION OF THE IN VITRO METABOLISM OF SELECTIVE ANDROGEN RECEPTOR MODULATOR USING HUMAN, RAT, AND DOG LIVER ENZYME PREPARATIONS
      Wenqing Gao, Zengru Wu, Casey E. Bohl, Jun Yang, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition February 2006, 34 (2) 243-253; DOI: https://doi.org/10.1124/dmd.105.007112
    2. You have access
      INTERSPECIES DIFFERENCES IN PHARMACOKINETICS AND METABOLISM OF S-3-(4-ACETYLAMINO-PHENOXY)-2-HYDROXY-2-METHYL-N-(4-NITRO-3-TRIFLUOROMETHYLPHENYL)-PROPIONAMIDE: THE ROLE OF N-ACETYLTRANSFERASE
      Wenqing Gao, Jeffrey S. Johnston, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition February 2006, 34 (2) 254-260; DOI: https://doi.org/10.1124/dmd.105.007120

E

  1. Evans, Allan M.

    1. You have access
      ROLE OF MRP2 IN THE HEPATIC DISPOSITION OF MYCOPHENOLIC ACID AND ITS GLUCURONIDE METABOLITES: EFFECT OF CYCLOSPORINE
      Ian S. Westley, Leonie R. Brogan, Raymond G. Morris, Allan M. Evans and Benedetta C. Sallustio
      Drug Metabolism and Disposition February 2006, 34 (2) 261-266; DOI: https://doi.org/10.1124/dmd.105.006122

F

  1. Fraser, Albert D.

    1. You have access
      BRAIN CYCLOSPORIN A LEVELS ARE DETERMINED BY ONTOGENIC REGULATION OF MDR1A EXPRESSION
      Kerry B. Goralski, Philip D. Acott, Albert D. Fraser, David Worth and Christopher J. Sinal
      Drug Metabolism and Disposition February 2006, 34 (2) 288-295; DOI: https://doi.org/10.1124/dmd.105.007427

G

  1. Gao, Wenqing

    1. You have access
      CHARACTERIZATION OF THE IN VITRO METABOLISM OF SELECTIVE ANDROGEN RECEPTOR MODULATOR USING HUMAN, RAT, AND DOG LIVER ENZYME PREPARATIONS
      Wenqing Gao, Zengru Wu, Casey E. Bohl, Jun Yang, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition February 2006, 34 (2) 243-253; DOI: https://doi.org/10.1124/dmd.105.007112
    2. You have access
      INTERSPECIES DIFFERENCES IN PHARMACOKINETICS AND METABOLISM OF S-3-(4-ACETYLAMINO-PHENOXY)-2-HYDROXY-2-METHYL-N-(4-NITRO-3-TRIFLUOROMETHYLPHENYL)-PROPIONAMIDE: THE ROLE OF N-ACETYLTRANSFERASE
      Wenqing Gao, Jeffrey S. Johnston, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition February 2006, 34 (2) 254-260; DOI: https://doi.org/10.1124/dmd.105.007120
  2. Goralski, Kerry B.

    1. You have access
      BRAIN CYCLOSPORIN A LEVELS ARE DETERMINED BY ONTOGENIC REGULATION OF MDR1A EXPRESSION
      Kerry B. Goralski, Philip D. Acott, Albert D. Fraser, David Worth and Christopher J. Sinal
      Drug Metabolism and Disposition February 2006, 34 (2) 288-295; DOI: https://doi.org/10.1124/dmd.105.007427
  3. Gupta, Anubha

    1. You have access
      BRAIN DISTRIBUTION OF CETIRIZINE ENANTIOMERS: COMPARISON OF THREE DIFFERENT TISSUE-TO-PLASMA PARTITION COEFFICIENTS: Kp, Kp,u, AND Kp,uu
      Anubha Gupta, Pierre Chatelain, Roy Massingham, E. Niclas Jonsson and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition February 2006, 34 (2) 318-323; DOI: https://doi.org/10.1124/dmd.105.007211

H

  1. Hadden, Chad E.

    1. You have access
      IN VIVO METABOLISM OF [14C]RUBOXISTAURIN IN DOGS, MICE, AND RATS FOLLOWING ORAL ADMINISTRATION AND THE STRUCTURE DETERMINATION OF ITS METABOLITES BY LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY AND NMR SPECTROSCOPY
      Robert J. Barbuch, Kristina Campanale, Chad E. Hadden, Milton Zmijewski, Ping Yi, Douglas D. O'Bannon, Jennifer L. Burkey and Palaniappan Kulanthaivel
      Drug Metabolism and Disposition February 2006, 34 (2) 213-224; DOI: https://doi.org/10.1124/dmd.105.007401
  2. Haefeli, Walter Emil

    1. You have access
      EVALUATION OF INHIBITORY POTENCIES FOR COMPOUNDS INHIBITING P-GLYCOPROTEIN BUT WITHOUT MAXIMUM EFFECTS: F2 VALUES
      Johanna Weiss and Walter Emil Haefeli
      Drug Metabolism and Disposition February 2006, 34 (2) 203-207; DOI: https://doi.org/10.1124/dmd.105.007377
  3. Hammarlund-Udenaes, Margareta

    1. You have access
      BRAIN DISTRIBUTION OF CETIRIZINE ENANTIOMERS: COMPARISON OF THREE DIFFERENT TISSUE-TO-PLASMA PARTITION COEFFICIENTS: Kp, Kp,u, AND Kp,uu
      Anubha Gupta, Pierre Chatelain, Roy Massingham, E. Niclas Jonsson and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition February 2006, 34 (2) 318-323; DOI: https://doi.org/10.1124/dmd.105.007211
  4. Hanson, Ronald

    1. You have access
      STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
      Donglu Zhang, Haiying Zhang, Nelly Aranibar, Ronald Hanson, Yande Huang, Peter T. Cheng, Shung Wu, Samuel Bonacorsi, Mingshe Zhu, Arun Swaminathan and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2006, 34 (2) 267-280; DOI: https://doi.org/10.1124/dmd.105.007153
  5. Hirunpanich, Vilasinee

    1. You have access
      DEMONSTRATION OF DOCOSAHEXAENOIC ACID AS A BIOAVAILABILITY ENHANCER FOR CYP3A SUBSTRATES: IN VITRO AND IN VIVO EVIDENCE USING CYCLOSPORIN IN RATS
      Vilasinee Hirunpanich, Jun Katagi, Benjabhorn Sethabouppha and Hitoshi Sato
      Drug Metabolism and Disposition February 2006, 34 (2) 305-310; DOI: https://doi.org/10.1124/dmd.105.007088
  6. Hochhaus, G.

    1. You have access
      METABOLISM OF MOMETASONE FUROATE AND BIOLOGICAL ACTIVITY OF THE METABOLITES
      S. Sahasranaman, M. Issar and G. Hochhaus
      Drug Metabolism and Disposition February 2006, 34 (2) 225-233; DOI: https://doi.org/10.1124/dmd.105.005702
  7. Honda, Katsuya

    1. You have access
      METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY-N,N-DIISOPROPYLTRYPTAMINE IN HUMANS: IDENTIFICATION AND QUANTIFICATION OF ITS URINARY METABOLITES
      Tooru Kamata, Munehiro Katagi, Hiroe T. Kamata, Akihiro Miki, Noriaki Shima, Kei Zaitsu, Mayumi Nishikawa, Einosuke Tanaka, Katsuya Honda and Hitoshi Tsuchihashi
      Drug Metabolism and Disposition February 2006, 34 (2) 281-287; DOI: https://doi.org/10.1124/dmd.105.005835
  8. Hsia, Te-Chun

    1. You have access
      INHIBITION OF LUNG CANCER CELL GROWTH BY QUERCETIN GLUCURONIDES VIA G2/M ARREST AND INDUCTION OF APOPTOSIS
      Jen-Hung Yang, Te-Chun Hsia, Hsiu-Maan Kuo, Pei-Dawn Lee Chao, Chi-Chung Chou, Yau-Huei Wei and Jing-Gung Chung
      Drug Metabolism and Disposition February 2006, 34 (2) 296-304; DOI: https://doi.org/10.1124/dmd.105.005280
  9. Huang, Yande

    1. You have access
      STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
      Donglu Zhang, Haiying Zhang, Nelly Aranibar, Ronald Hanson, Yande Huang, Peter T. Cheng, Shung Wu, Samuel Bonacorsi, Mingshe Zhu, Arun Swaminathan and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2006, 34 (2) 267-280; DOI: https://doi.org/10.1124/dmd.105.007153
  10. Humphreys, W. Griffith

    1. You have access
      STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
      Donglu Zhang, Haiying Zhang, Nelly Aranibar, Ronald Hanson, Yande Huang, Peter T. Cheng, Shung Wu, Samuel Bonacorsi, Mingshe Zhu, Arun Swaminathan and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2006, 34 (2) 267-280; DOI: https://doi.org/10.1124/dmd.105.007153

I

  1. Issar, M.

    1. You have access
      METABOLISM OF MOMETASONE FUROATE AND BIOLOGICAL ACTIVITY OF THE METABOLITES
      S. Sahasranaman, M. Issar and G. Hochhaus
      Drug Metabolism and Disposition February 2006, 34 (2) 225-233; DOI: https://doi.org/10.1124/dmd.105.005702

J

  1. Johnston, Jeffrey S.

    1. You have access
      INTERSPECIES DIFFERENCES IN PHARMACOKINETICS AND METABOLISM OF S-3-(4-ACETYLAMINO-PHENOXY)-2-HYDROXY-2-METHYL-N-(4-NITRO-3-TRIFLUOROMETHYLPHENYL)-PROPIONAMIDE: THE ROLE OF N-ACETYLTRANSFERASE
      Wenqing Gao, Jeffrey S. Johnston, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition February 2006, 34 (2) 254-260; DOI: https://doi.org/10.1124/dmd.105.007120
  2. Jonsson, E. Niclas

    1. You have access
      BRAIN DISTRIBUTION OF CETIRIZINE ENANTIOMERS: COMPARISON OF THREE DIFFERENT TISSUE-TO-PLASMA PARTITION COEFFICIENTS: Kp, Kp,u, AND Kp,uu
      Anubha Gupta, Pierre Chatelain, Roy Massingham, E. Niclas Jonsson and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition February 2006, 34 (2) 318-323; DOI: https://doi.org/10.1124/dmd.105.007211

K

  1. Kamata, Hiroe T.

    1. You have access
      METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY-N,N-DIISOPROPYLTRYPTAMINE IN HUMANS: IDENTIFICATION AND QUANTIFICATION OF ITS URINARY METABOLITES
      Tooru Kamata, Munehiro Katagi, Hiroe T. Kamata, Akihiro Miki, Noriaki Shima, Kei Zaitsu, Mayumi Nishikawa, Einosuke Tanaka, Katsuya Honda and Hitoshi Tsuchihashi
      Drug Metabolism and Disposition February 2006, 34 (2) 281-287; DOI: https://doi.org/10.1124/dmd.105.005835
  2. Kamata, Tooru

    1. You have access
      METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY-N,N-DIISOPROPYLTRYPTAMINE IN HUMANS: IDENTIFICATION AND QUANTIFICATION OF ITS URINARY METABOLITES
      Tooru Kamata, Munehiro Katagi, Hiroe T. Kamata, Akihiro Miki, Noriaki Shima, Kei Zaitsu, Mayumi Nishikawa, Einosuke Tanaka, Katsuya Honda and Hitoshi Tsuchihashi
      Drug Metabolism and Disposition February 2006, 34 (2) 281-287; DOI: https://doi.org/10.1124/dmd.105.005835
  3. Katagi, Jun

    1. You have access
      DEMONSTRATION OF DOCOSAHEXAENOIC ACID AS A BIOAVAILABILITY ENHANCER FOR CYP3A SUBSTRATES: IN VITRO AND IN VIVO EVIDENCE USING CYCLOSPORIN IN RATS
      Vilasinee Hirunpanich, Jun Katagi, Benjabhorn Sethabouppha and Hitoshi Sato
      Drug Metabolism and Disposition February 2006, 34 (2) 305-310; DOI: https://doi.org/10.1124/dmd.105.007088
  4. Katagi, Munehiro

    1. You have access
      METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY-N,N-DIISOPROPYLTRYPTAMINE IN HUMANS: IDENTIFICATION AND QUANTIFICATION OF ITS URINARY METABOLITES
      Tooru Kamata, Munehiro Katagi, Hiroe T. Kamata, Akihiro Miki, Noriaki Shima, Kei Zaitsu, Mayumi Nishikawa, Einosuke Tanaka, Katsuya Honda and Hitoshi Tsuchihashi
      Drug Metabolism and Disposition February 2006, 34 (2) 281-287; DOI: https://doi.org/10.1124/dmd.105.005835
  5. Kim, Sung Yeon

    1. You have access
      INEFFICIENT REPAIR OF TAMOXIFEN-DNA ADDUCTS IN RATS AND MICE
      Sung Yeon Kim, Naomi Suzuki, Y. R. Santosh Laxmi and Shinya Shibutani
      Drug Metabolism and Disposition February 2006, 34 (2) 311-317; DOI: https://doi.org/10.1124/dmd.105.007013
  6. Kitamura, Shigeyuki

    1. You have access
      ESTIMATION OF ALDEHYDE OXIDASE ACTIVITY IN VIVO FROM CONVERSION RATIO OF N1-METHYLNICOTINAMIDE TO PYRIDONES, AND INTRASPECIES VARIATION OF THE ENZYME ACTIVITY IN RATS
      Kazumi Sugihara, Yoshitaka Tayama, Kazuhiro Shimomiya, Daisuke Yoshimoto, Shigeru Ohta and Shigeyuki Kitamura
      Drug Metabolism and Disposition February 2006, 34 (2) 208-212; DOI: https://doi.org/10.1124/dmd.105.006544
  7. Kuehl, Gwendolyn E.

    1. You have access
      GLUCURONIDATION OF THE ASPIRIN METABOLITE SALICYLIC ACID BY EXPRESSED UDP-GLUCURONOSYLTRANSFERASES AND HUMAN LIVER MICROSOMES
      Gwendolyn E. Kuehl, Jeannette Bigler, John D. Potter and Johanna W. Lampe
      Drug Metabolism and Disposition February 2006, 34 (2) 199-202; DOI: https://doi.org/10.1124/dmd.105.005652
  8. Kulanthaivel, Palaniappan

    1. You have access
      IN VIVO METABOLISM OF [14C]RUBOXISTAURIN IN DOGS, MICE, AND RATS FOLLOWING ORAL ADMINISTRATION AND THE STRUCTURE DETERMINATION OF ITS METABOLITES BY LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY AND NMR SPECTROSCOPY
      Robert J. Barbuch, Kristina Campanale, Chad E. Hadden, Milton Zmijewski, Ping Yi, Douglas D. O'Bannon, Jennifer L. Burkey and Palaniappan Kulanthaivel
      Drug Metabolism and Disposition February 2006, 34 (2) 213-224; DOI: https://doi.org/10.1124/dmd.105.007401
  9. Kuo, Hsiu-Maan

    1. You have access
      INHIBITION OF LUNG CANCER CELL GROWTH BY QUERCETIN GLUCURONIDES VIA G2/M ARREST AND INDUCTION OF APOPTOSIS
      Jen-Hung Yang, Te-Chun Hsia, Hsiu-Maan Kuo, Pei-Dawn Lee Chao, Chi-Chung Chou, Yau-Huei Wei and Jing-Gung Chung
      Drug Metabolism and Disposition February 2006, 34 (2) 296-304; DOI: https://doi.org/10.1124/dmd.105.005280

L

  1. Lampe, Johanna W.

    1. You have access
      GLUCURONIDATION OF THE ASPIRIN METABOLITE SALICYLIC ACID BY EXPRESSED UDP-GLUCURONOSYLTRANSFERASES AND HUMAN LIVER MICROSOMES
      Gwendolyn E. Kuehl, Jeannette Bigler, John D. Potter and Johanna W. Lampe
      Drug Metabolism and Disposition February 2006, 34 (2) 199-202; DOI: https://doi.org/10.1124/dmd.105.005652
  2. Laxmi, Y. R. Santosh

    1. You have access
      INEFFICIENT REPAIR OF TAMOXIFEN-DNA ADDUCTS IN RATS AND MICE
      Sung Yeon Kim, Naomi Suzuki, Y. R. Santosh Laxmi and Shinya Shibutani
      Drug Metabolism and Disposition February 2006, 34 (2) 311-317; DOI: https://doi.org/10.1124/dmd.105.007013
  3. Lennard, M. S.

    1. You have access
      DEVELOPMENT OF NOVEL FURANOCOUMARIN DIMERS AS POTENT AND SELECTIVE INHIBITORS OF CYP3A4
      E. Row, S. A. Brown, A. V. Stachulski and M. S. Lennard
      Drug Metabolism and Disposition February 2006, 34 (2) 324-330; DOI: https://doi.org/10.1124/dmd.105.007294

M

  1. Massingham, Roy

    1. You have access
      BRAIN DISTRIBUTION OF CETIRIZINE ENANTIOMERS: COMPARISON OF THREE DIFFERENT TISSUE-TO-PLASMA PARTITION COEFFICIENTS: Kp, Kp,u, AND Kp,uu
      Anubha Gupta, Pierre Chatelain, Roy Massingham, E. Niclas Jonsson and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition February 2006, 34 (2) 318-323; DOI: https://doi.org/10.1124/dmd.105.007211
  2. Miki, Akihiro

    1. You have access
      METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY-N,N-DIISOPROPYLTRYPTAMINE IN HUMANS: IDENTIFICATION AND QUANTIFICATION OF ITS URINARY METABOLITES
      Tooru Kamata, Munehiro Katagi, Hiroe T. Kamata, Akihiro Miki, Noriaki Shima, Kei Zaitsu, Mayumi Nishikawa, Einosuke Tanaka, Katsuya Honda and Hitoshi Tsuchihashi
      Drug Metabolism and Disposition February 2006, 34 (2) 281-287; DOI: https://doi.org/10.1124/dmd.105.005835
  3. Miller, Duane D.

    1. You have access
      CHARACTERIZATION OF THE IN VITRO METABOLISM OF SELECTIVE ANDROGEN RECEPTOR MODULATOR USING HUMAN, RAT, AND DOG LIVER ENZYME PREPARATIONS
      Wenqing Gao, Zengru Wu, Casey E. Bohl, Jun Yang, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition February 2006, 34 (2) 243-253; DOI: https://doi.org/10.1124/dmd.105.007112
    2. You have access
      INTERSPECIES DIFFERENCES IN PHARMACOKINETICS AND METABOLISM OF S-3-(4-ACETYLAMINO-PHENOXY)-2-HYDROXY-2-METHYL-N-(4-NITRO-3-TRIFLUOROMETHYLPHENYL)-PROPIONAMIDE: THE ROLE OF N-ACETYLTRANSFERASE
      Wenqing Gao, Jeffrey S. Johnston, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition February 2006, 34 (2) 254-260; DOI: https://doi.org/10.1124/dmd.105.007120
  4. Morris, Raymond G.

    1. You have access
      ROLE OF MRP2 IN THE HEPATIC DISPOSITION OF MYCOPHENOLIC ACID AND ITS GLUCURONIDE METABOLITES: EFFECT OF CYCLOSPORINE
      Ian S. Westley, Leonie R. Brogan, Raymond G. Morris, Allan M. Evans and Benedetta C. Sallustio
      Drug Metabolism and Disposition February 2006, 34 (2) 261-266; DOI: https://doi.org/10.1124/dmd.105.006122

N

  1. Nagayama, Sekio

    1. You have access
      DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR
      Hidetoshi Yamaya, Mayuko Saeki, Ken-ichiro Yoshida, Jiro Shibata, Shingo Yano, Yoshiaki Sato, Atsushi Takao, Takashi Shindo, Aman U. Buzdar and Sekio Nagayama
      Drug Metabolism and Disposition February 2006, 34 (2) 331-338; DOI: https://doi.org/10.1124/dmd.105.005504
  2. Nishikawa, Mayumi

    1. You have access
      METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY-N,N-DIISOPROPYLTRYPTAMINE IN HUMANS: IDENTIFICATION AND QUANTIFICATION OF ITS URINARY METABOLITES
      Tooru Kamata, Munehiro Katagi, Hiroe T. Kamata, Akihiro Miki, Noriaki Shima, Kei Zaitsu, Mayumi Nishikawa, Einosuke Tanaka, Katsuya Honda and Hitoshi Tsuchihashi
      Drug Metabolism and Disposition February 2006, 34 (2) 281-287; DOI: https://doi.org/10.1124/dmd.105.005835

O

  1. O'Bannon, Douglas D.

    1. You have access
      IN VIVO METABOLISM OF [14C]RUBOXISTAURIN IN DOGS, MICE, AND RATS FOLLOWING ORAL ADMINISTRATION AND THE STRUCTURE DETERMINATION OF ITS METABOLITES BY LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY AND NMR SPECTROSCOPY
      Robert J. Barbuch, Kristina Campanale, Chad E. Hadden, Milton Zmijewski, Ping Yi, Douglas D. O'Bannon, Jennifer L. Burkey and Palaniappan Kulanthaivel
      Drug Metabolism and Disposition February 2006, 34 (2) 213-224; DOI: https://doi.org/10.1124/dmd.105.007401
  2. Ohta, Shigeru

    1. You have access
      ESTIMATION OF ALDEHYDE OXIDASE ACTIVITY IN VIVO FROM CONVERSION RATIO OF N1-METHYLNICOTINAMIDE TO PYRIDONES, AND INTRASPECIES VARIATION OF THE ENZYME ACTIVITY IN RATS
      Kazumi Sugihara, Yoshitaka Tayama, Kazuhiro Shimomiya, Daisuke Yoshimoto, Shigeru Ohta and Shigeyuki Kitamura
      Drug Metabolism and Disposition February 2006, 34 (2) 208-212; DOI: https://doi.org/10.1124/dmd.105.006544

P

  1. Potter, John D.

    1. You have access
      GLUCURONIDATION OF THE ASPIRIN METABOLITE SALICYLIC ACID BY EXPRESSED UDP-GLUCURONOSYLTRANSFERASES AND HUMAN LIVER MICROSOMES
      Gwendolyn E. Kuehl, Jeannette Bigler, John D. Potter and Johanna W. Lampe
      Drug Metabolism and Disposition February 2006, 34 (2) 199-202; DOI: https://doi.org/10.1124/dmd.105.005652

R

  1. Row, E.

    1. You have access
      DEVELOPMENT OF NOVEL FURANOCOUMARIN DIMERS AS POTENT AND SELECTIVE INHIBITORS OF CYP3A4
      E. Row, S. A. Brown, A. V. Stachulski and M. S. Lennard
      Drug Metabolism and Disposition February 2006, 34 (2) 324-330; DOI: https://doi.org/10.1124/dmd.105.007294

S

  1. Saeki, Mayuko

    1. You have access
      DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR
      Hidetoshi Yamaya, Mayuko Saeki, Ken-ichiro Yoshida, Jiro Shibata, Shingo Yano, Yoshiaki Sato, Atsushi Takao, Takashi Shindo, Aman U. Buzdar and Sekio Nagayama
      Drug Metabolism and Disposition February 2006, 34 (2) 331-338; DOI: https://doi.org/10.1124/dmd.105.005504
  2. Sahasranaman, S.

    1. You have access
      METABOLISM OF MOMETASONE FUROATE AND BIOLOGICAL ACTIVITY OF THE METABOLITES
      S. Sahasranaman, M. Issar and G. Hochhaus
      Drug Metabolism and Disposition February 2006, 34 (2) 225-233; DOI: https://doi.org/10.1124/dmd.105.005702
  3. Sallustio, Benedetta C.

    1. You have access
      ROLE OF MRP2 IN THE HEPATIC DISPOSITION OF MYCOPHENOLIC ACID AND ITS GLUCURONIDE METABOLITES: EFFECT OF CYCLOSPORINE
      Ian S. Westley, Leonie R. Brogan, Raymond G. Morris, Allan M. Evans and Benedetta C. Sallustio
      Drug Metabolism and Disposition February 2006, 34 (2) 261-266; DOI: https://doi.org/10.1124/dmd.105.006122
  4. Sato, Hitoshi

    1. You have access
      DEMONSTRATION OF DOCOSAHEXAENOIC ACID AS A BIOAVAILABILITY ENHANCER FOR CYP3A SUBSTRATES: IN VITRO AND IN VIVO EVIDENCE USING CYCLOSPORIN IN RATS
      Vilasinee Hirunpanich, Jun Katagi, Benjabhorn Sethabouppha and Hitoshi Sato
      Drug Metabolism and Disposition February 2006, 34 (2) 305-310; DOI: https://doi.org/10.1124/dmd.105.007088
  5. Sato, Yoshiaki

    1. You have access
      DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR
      Hidetoshi Yamaya, Mayuko Saeki, Ken-ichiro Yoshida, Jiro Shibata, Shingo Yano, Yoshiaki Sato, Atsushi Takao, Takashi Shindo, Aman U. Buzdar and Sekio Nagayama
      Drug Metabolism and Disposition February 2006, 34 (2) 331-338; DOI: https://doi.org/10.1124/dmd.105.005504
  6. Sethabouppha, Benjabhorn

    1. You have access
      DEMONSTRATION OF DOCOSAHEXAENOIC ACID AS A BIOAVAILABILITY ENHANCER FOR CYP3A SUBSTRATES: IN VITRO AND IN VIVO EVIDENCE USING CYCLOSPORIN IN RATS
      Vilasinee Hirunpanich, Jun Katagi, Benjabhorn Sethabouppha and Hitoshi Sato
      Drug Metabolism and Disposition February 2006, 34 (2) 305-310; DOI: https://doi.org/10.1124/dmd.105.007088
  7. Shibata, Jiro

    1. You have access
      DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR
      Hidetoshi Yamaya, Mayuko Saeki, Ken-ichiro Yoshida, Jiro Shibata, Shingo Yano, Yoshiaki Sato, Atsushi Takao, Takashi Shindo, Aman U. Buzdar and Sekio Nagayama
      Drug Metabolism and Disposition February 2006, 34 (2) 331-338; DOI: https://doi.org/10.1124/dmd.105.005504
  8. Shibutani, Shinya

    1. You have access
      INEFFICIENT REPAIR OF TAMOXIFEN-DNA ADDUCTS IN RATS AND MICE
      Sung Yeon Kim, Naomi Suzuki, Y. R. Santosh Laxmi and Shinya Shibutani
      Drug Metabolism and Disposition February 2006, 34 (2) 311-317; DOI: https://doi.org/10.1124/dmd.105.007013
  9. Shima, Noriaki

    1. You have access
      METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY-N,N-DIISOPROPYLTRYPTAMINE IN HUMANS: IDENTIFICATION AND QUANTIFICATION OF ITS URINARY METABOLITES
      Tooru Kamata, Munehiro Katagi, Hiroe T. Kamata, Akihiro Miki, Noriaki Shima, Kei Zaitsu, Mayumi Nishikawa, Einosuke Tanaka, Katsuya Honda and Hitoshi Tsuchihashi
      Drug Metabolism and Disposition February 2006, 34 (2) 281-287; DOI: https://doi.org/10.1124/dmd.105.005835
  10. Shimomiya, Kazuhiro

    1. You have access
      ESTIMATION OF ALDEHYDE OXIDASE ACTIVITY IN VIVO FROM CONVERSION RATIO OF N1-METHYLNICOTINAMIDE TO PYRIDONES, AND INTRASPECIES VARIATION OF THE ENZYME ACTIVITY IN RATS
      Kazumi Sugihara, Yoshitaka Tayama, Kazuhiro Shimomiya, Daisuke Yoshimoto, Shigeru Ohta and Shigeyuki Kitamura
      Drug Metabolism and Disposition February 2006, 34 (2) 208-212; DOI: https://doi.org/10.1124/dmd.105.006544
  11. Shindo, Takashi

    1. You have access
      DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR
      Hidetoshi Yamaya, Mayuko Saeki, Ken-ichiro Yoshida, Jiro Shibata, Shingo Yano, Yoshiaki Sato, Atsushi Takao, Takashi Shindo, Aman U. Buzdar and Sekio Nagayama
      Drug Metabolism and Disposition February 2006, 34 (2) 331-338; DOI: https://doi.org/10.1124/dmd.105.005504
  12. Sinal, Christopher J.

    1. You have access
      BRAIN CYCLOSPORIN A LEVELS ARE DETERMINED BY ONTOGENIC REGULATION OF MDR1A EXPRESSION
      Kerry B. Goralski, Philip D. Acott, Albert D. Fraser, David Worth and Christopher J. Sinal
      Drug Metabolism and Disposition February 2006, 34 (2) 288-295; DOI: https://doi.org/10.1124/dmd.105.007427
  13. Stachulski, A. V.

    1. You have access
      DEVELOPMENT OF NOVEL FURANOCOUMARIN DIMERS AS POTENT AND SELECTIVE INHIBITORS OF CYP3A4
      E. Row, S. A. Brown, A. V. Stachulski and M. S. Lennard
      Drug Metabolism and Disposition February 2006, 34 (2) 324-330; DOI: https://doi.org/10.1124/dmd.105.007294
  14. Sugihara, Kazumi

    1. You have access
      ESTIMATION OF ALDEHYDE OXIDASE ACTIVITY IN VIVO FROM CONVERSION RATIO OF N1-METHYLNICOTINAMIDE TO PYRIDONES, AND INTRASPECIES VARIATION OF THE ENZYME ACTIVITY IN RATS
      Kazumi Sugihara, Yoshitaka Tayama, Kazuhiro Shimomiya, Daisuke Yoshimoto, Shigeru Ohta and Shigeyuki Kitamura
      Drug Metabolism and Disposition February 2006, 34 (2) 208-212; DOI: https://doi.org/10.1124/dmd.105.006544
  15. Suzuki, Naomi

    1. You have access
      INEFFICIENT REPAIR OF TAMOXIFEN-DNA ADDUCTS IN RATS AND MICE
      Sung Yeon Kim, Naomi Suzuki, Y. R. Santosh Laxmi and Shinya Shibutani
      Drug Metabolism and Disposition February 2006, 34 (2) 311-317; DOI: https://doi.org/10.1124/dmd.105.007013
  16. Swaminathan, Arun

    1. You have access
      STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
      Donglu Zhang, Haiying Zhang, Nelly Aranibar, Ronald Hanson, Yande Huang, Peter T. Cheng, Shung Wu, Samuel Bonacorsi, Mingshe Zhu, Arun Swaminathan and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2006, 34 (2) 267-280; DOI: https://doi.org/10.1124/dmd.105.007153

T

  1. Takao, Atsushi

    1. You have access
      DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR
      Hidetoshi Yamaya, Mayuko Saeki, Ken-ichiro Yoshida, Jiro Shibata, Shingo Yano, Yoshiaki Sato, Atsushi Takao, Takashi Shindo, Aman U. Buzdar and Sekio Nagayama
      Drug Metabolism and Disposition February 2006, 34 (2) 331-338; DOI: https://doi.org/10.1124/dmd.105.005504
  2. Tanaka, Einosuke

    1. You have access
      METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY-N,N-DIISOPROPYLTRYPTAMINE IN HUMANS: IDENTIFICATION AND QUANTIFICATION OF ITS URINARY METABOLITES
      Tooru Kamata, Munehiro Katagi, Hiroe T. Kamata, Akihiro Miki, Noriaki Shima, Kei Zaitsu, Mayumi Nishikawa, Einosuke Tanaka, Katsuya Honda and Hitoshi Tsuchihashi
      Drug Metabolism and Disposition February 2006, 34 (2) 281-287; DOI: https://doi.org/10.1124/dmd.105.005835
  3. Tayama, Yoshitaka

    1. You have access
      ESTIMATION OF ALDEHYDE OXIDASE ACTIVITY IN VIVO FROM CONVERSION RATIO OF N1-METHYLNICOTINAMIDE TO PYRIDONES, AND INTRASPECIES VARIATION OF THE ENZYME ACTIVITY IN RATS
      Kazumi Sugihara, Yoshitaka Tayama, Kazuhiro Shimomiya, Daisuke Yoshimoto, Shigeru Ohta and Shigeyuki Kitamura
      Drug Metabolism and Disposition February 2006, 34 (2) 208-212; DOI: https://doi.org/10.1124/dmd.105.006544
  4. Teng, Xiao Wei

    1. You have access
      DISTINCT ROLE OF BILOBALIDE AND GINKGOLIDE A IN THE MODULATION OF RAT CYP2B1 AND CYP3A23 GENE EXPRESSION BY GINKGO BILOBA EXTRACT IN CULTURED HEPATOCYTES
      Thomas K. H. Chang, Jie Chen and Xiao Wei Teng
      Drug Metabolism and Disposition February 2006, 34 (2) 234-242; DOI: https://doi.org/10.1124/dmd.105.005751
  5. Tsuchihashi, Hitoshi

    1. You have access
      METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY-N,N-DIISOPROPYLTRYPTAMINE IN HUMANS: IDENTIFICATION AND QUANTIFICATION OF ITS URINARY METABOLITES
      Tooru Kamata, Munehiro Katagi, Hiroe T. Kamata, Akihiro Miki, Noriaki Shima, Kei Zaitsu, Mayumi Nishikawa, Einosuke Tanaka, Katsuya Honda and Hitoshi Tsuchihashi
      Drug Metabolism and Disposition February 2006, 34 (2) 281-287; DOI: https://doi.org/10.1124/dmd.105.005835

W

  1. Wei, Yau-Huei

    1. You have access
      INHIBITION OF LUNG CANCER CELL GROWTH BY QUERCETIN GLUCURONIDES VIA G2/M ARREST AND INDUCTION OF APOPTOSIS
      Jen-Hung Yang, Te-Chun Hsia, Hsiu-Maan Kuo, Pei-Dawn Lee Chao, Chi-Chung Chou, Yau-Huei Wei and Jing-Gung Chung
      Drug Metabolism and Disposition February 2006, 34 (2) 296-304; DOI: https://doi.org/10.1124/dmd.105.005280
  2. Weiss, Johanna

    1. You have access
      EVALUATION OF INHIBITORY POTENCIES FOR COMPOUNDS INHIBITING P-GLYCOPROTEIN BUT WITHOUT MAXIMUM EFFECTS: F2 VALUES
      Johanna Weiss and Walter Emil Haefeli
      Drug Metabolism and Disposition February 2006, 34 (2) 203-207; DOI: https://doi.org/10.1124/dmd.105.007377
  3. Westley, Ian S.

    1. You have access
      ROLE OF MRP2 IN THE HEPATIC DISPOSITION OF MYCOPHENOLIC ACID AND ITS GLUCURONIDE METABOLITES: EFFECT OF CYCLOSPORINE
      Ian S. Westley, Leonie R. Brogan, Raymond G. Morris, Allan M. Evans and Benedetta C. Sallustio
      Drug Metabolism and Disposition February 2006, 34 (2) 261-266; DOI: https://doi.org/10.1124/dmd.105.006122
  4. Worth, David

    1. You have access
      BRAIN CYCLOSPORIN A LEVELS ARE DETERMINED BY ONTOGENIC REGULATION OF MDR1A EXPRESSION
      Kerry B. Goralski, Philip D. Acott, Albert D. Fraser, David Worth and Christopher J. Sinal
      Drug Metabolism and Disposition February 2006, 34 (2) 288-295; DOI: https://doi.org/10.1124/dmd.105.007427
  5. Wu, Shung

    1. You have access
      STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
      Donglu Zhang, Haiying Zhang, Nelly Aranibar, Ronald Hanson, Yande Huang, Peter T. Cheng, Shung Wu, Samuel Bonacorsi, Mingshe Zhu, Arun Swaminathan and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2006, 34 (2) 267-280; DOI: https://doi.org/10.1124/dmd.105.007153
  6. Wu, Zengru

    1. You have access
      CHARACTERIZATION OF THE IN VITRO METABOLISM OF SELECTIVE ANDROGEN RECEPTOR MODULATOR USING HUMAN, RAT, AND DOG LIVER ENZYME PREPARATIONS
      Wenqing Gao, Zengru Wu, Casey E. Bohl, Jun Yang, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition February 2006, 34 (2) 243-253; DOI: https://doi.org/10.1124/dmd.105.007112

Y

  1. Yamaya, Hidetoshi

    1. You have access
      DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR
      Hidetoshi Yamaya, Mayuko Saeki, Ken-ichiro Yoshida, Jiro Shibata, Shingo Yano, Yoshiaki Sato, Atsushi Takao, Takashi Shindo, Aman U. Buzdar and Sekio Nagayama
      Drug Metabolism and Disposition February 2006, 34 (2) 331-338; DOI: https://doi.org/10.1124/dmd.105.005504
  2. Yang, Jen-Hung

    1. You have access
      INHIBITION OF LUNG CANCER CELL GROWTH BY QUERCETIN GLUCURONIDES VIA G2/M ARREST AND INDUCTION OF APOPTOSIS
      Jen-Hung Yang, Te-Chun Hsia, Hsiu-Maan Kuo, Pei-Dawn Lee Chao, Chi-Chung Chou, Yau-Huei Wei and Jing-Gung Chung
      Drug Metabolism and Disposition February 2006, 34 (2) 296-304; DOI: https://doi.org/10.1124/dmd.105.005280
  3. Yang, Jun

    1. You have access
      CHARACTERIZATION OF THE IN VITRO METABOLISM OF SELECTIVE ANDROGEN RECEPTOR MODULATOR USING HUMAN, RAT, AND DOG LIVER ENZYME PREPARATIONS
      Wenqing Gao, Zengru Wu, Casey E. Bohl, Jun Yang, Duane D. Miller and James T. Dalton
      Drug Metabolism and Disposition February 2006, 34 (2) 243-253; DOI: https://doi.org/10.1124/dmd.105.007112
  4. Yano, Shingo

    1. You have access
      DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR
      Hidetoshi Yamaya, Mayuko Saeki, Ken-ichiro Yoshida, Jiro Shibata, Shingo Yano, Yoshiaki Sato, Atsushi Takao, Takashi Shindo, Aman U. Buzdar and Sekio Nagayama
      Drug Metabolism and Disposition February 2006, 34 (2) 331-338; DOI: https://doi.org/10.1124/dmd.105.005504
  5. Yi, Ping

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      IN VIVO METABOLISM OF [14C]RUBOXISTAURIN IN DOGS, MICE, AND RATS FOLLOWING ORAL ADMINISTRATION AND THE STRUCTURE DETERMINATION OF ITS METABOLITES BY LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY AND NMR SPECTROSCOPY
      Robert J. Barbuch, Kristina Campanale, Chad E. Hadden, Milton Zmijewski, Ping Yi, Douglas D. O'Bannon, Jennifer L. Burkey and Palaniappan Kulanthaivel
      Drug Metabolism and Disposition February 2006, 34 (2) 213-224; DOI: https://doi.org/10.1124/dmd.105.007401
  6. Yoshida, Ken-ichiro

    1. You have access
      DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR
      Hidetoshi Yamaya, Mayuko Saeki, Ken-ichiro Yoshida, Jiro Shibata, Shingo Yano, Yoshiaki Sato, Atsushi Takao, Takashi Shindo, Aman U. Buzdar and Sekio Nagayama
      Drug Metabolism and Disposition February 2006, 34 (2) 331-338; DOI: https://doi.org/10.1124/dmd.105.005504
  7. Yoshimoto, Daisuke

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      ESTIMATION OF ALDEHYDE OXIDASE ACTIVITY IN VIVO FROM CONVERSION RATIO OF N1-METHYLNICOTINAMIDE TO PYRIDONES, AND INTRASPECIES VARIATION OF THE ENZYME ACTIVITY IN RATS
      Kazumi Sugihara, Yoshitaka Tayama, Kazuhiro Shimomiya, Daisuke Yoshimoto, Shigeru Ohta and Shigeyuki Kitamura
      Drug Metabolism and Disposition February 2006, 34 (2) 208-212; DOI: https://doi.org/10.1124/dmd.105.006544

Z

  1. Zaitsu, Kei

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      METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY-N,N-DIISOPROPYLTRYPTAMINE IN HUMANS: IDENTIFICATION AND QUANTIFICATION OF ITS URINARY METABOLITES
      Tooru Kamata, Munehiro Katagi, Hiroe T. Kamata, Akihiro Miki, Noriaki Shima, Kei Zaitsu, Mayumi Nishikawa, Einosuke Tanaka, Katsuya Honda and Hitoshi Tsuchihashi
      Drug Metabolism and Disposition February 2006, 34 (2) 281-287; DOI: https://doi.org/10.1124/dmd.105.005835
  2. Zhang, Donglu

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      STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
      Donglu Zhang, Haiying Zhang, Nelly Aranibar, Ronald Hanson, Yande Huang, Peter T. Cheng, Shung Wu, Samuel Bonacorsi, Mingshe Zhu, Arun Swaminathan and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2006, 34 (2) 267-280; DOI: https://doi.org/10.1124/dmd.105.007153
  3. Zhang, Haiying

    1. You have access
      STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
      Donglu Zhang, Haiying Zhang, Nelly Aranibar, Ronald Hanson, Yande Huang, Peter T. Cheng, Shung Wu, Samuel Bonacorsi, Mingshe Zhu, Arun Swaminathan and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2006, 34 (2) 267-280; DOI: https://doi.org/10.1124/dmd.105.007153
  4. Zhu, Mingshe

    1. You have access
      STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
      Donglu Zhang, Haiying Zhang, Nelly Aranibar, Ronald Hanson, Yande Huang, Peter T. Cheng, Shung Wu, Samuel Bonacorsi, Mingshe Zhu, Arun Swaminathan and W. Griffith Humphreys
      Drug Metabolism and Disposition February 2006, 34 (2) 267-280; DOI: https://doi.org/10.1124/dmd.105.007153
  5. Zmijewski, Milton

    1. You have access
      IN VIVO METABOLISM OF [14C]RUBOXISTAURIN IN DOGS, MICE, AND RATS FOLLOWING ORAL ADMINISTRATION AND THE STRUCTURE DETERMINATION OF ITS METABOLITES BY LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY AND NMR SPECTROSCOPY
      Robert J. Barbuch, Kristina Campanale, Chad E. Hadden, Milton Zmijewski, Ping Yi, Douglas D. O'Bannon, Jennifer L. Burkey and Palaniappan Kulanthaivel
      Drug Metabolism and Disposition February 2006, 34 (2) 213-224; DOI: https://doi.org/10.1124/dmd.105.007401
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Drug Metabolism and Disposition: 34 (2)
Drug Metabolism and Disposition
Vol. 34, Issue 2
1 Feb 2006
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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