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Research ArticleArticle

METABOLISM AND EXCRETION OF ERLOTINIB, A SMALL MOLECULE INHIBITOR OF EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE, IN HEALTHY MALE VOLUNTEERS

Jie Ling, Kim A. Johnson, Zhuang Miao, Ashok Rakhit, Michael P. Pantze, Marta Hamilton, Bert L. Lum and Chandra Prakash
Drug Metabolism and Disposition March 2006, 34 (3) 420-426; DOI: https://doi.org/10.1124/dmd.105.007765

Article Information

vol. 34 no. 3 420-426
DOI 
https://doi.org/10.1124/dmd.105.007765
PubMed 
16381666
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 10, 2005
  • Accepted December 19, 2005
  • Published online February 21, 2006.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jie Ling,
  2. Kim A. Johnson,
  3. Zhuang Miao,
  4. Ashok Rakhit,
  5. Michael P. Pantze,
  6. Marta Hamilton,
  7. Bert L. Lum and
  8. Chandra Prakash
  1. Department of Pharmacokinetic, Pharmacodynamic, and Bioanalytical Sciences, Genentech Incorporated, South San Francisco, California (J.L., B.L.L.); Departments of Pharmacokinetics, Dynamics & Metabolism, Pfizer Global Research and Development, Groton, Connecticut (K.A.J., Z.M., C.P.); Hoffmann-La Roche Pharmaceuticals, Nutley, New Jersey (A.R., M.P.P.); and OSI Pharmaceuticals, Boulder, Colorado (M.H.)
  1. Address correspondence to:
    Dr. Bert L. Lum, Department of Pharmacokinetic and Pharmacodynamic Sciences, Genentech, Inc., 1 DNA Way (MS-70), South San Francisco, CA 94080. E-mail: blum{at}gene.com
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Research ArticleArticle

METABOLISM AND EXCRETION OF ERLOTINIB, A SMALL MOLECULE INHIBITOR OF EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE, IN HEALTHY MALE VOLUNTEERS

Jie Ling, Kim A. Johnson, Zhuang Miao, Ashok Rakhit, Michael P. Pantze, Marta Hamilton, Bert L. Lum and Chandra Prakash
Drug Metabolism and Disposition March 1, 2006, 34 (3) 420-426; DOI: https://doi.org/10.1124/dmd.105.007765
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