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Index by author

April 01, 2006; Volume 34,Issue 4

A

  1. Abdelmegeed, Mohamed A.

    1. THE MITOGEN-ACTIVATED PROTEIN KINASE KINASE (MEK) INHIBITOR PD98059 ELEVATES PRIMARY CULTURED RAT HEPATOCYTE GLUTATHIONE LEVELS INDEPENDENT OF INHIBITING MEK
      Sang K. Kim, Mohamed A. Abdelmegeed and Raymond F. Novak
      Drug Metabolism and Disposition April 2006, 34 (4) 683-689; DOI: https://doi.org/10.1124/dmd.105.007666

  2. Abildskov, Kirsten M.

    1. FETAL MORPHINE METABOLISM AND CLEARANCE ARE CONSTANT DURING LATE GESTATION
      Marianne Garland, Kirsten M. Abildskov, Samantha Taylor, Kenza Benzeroual, Casper S. Caspersen, Sylvia E. Arroyo, Tung-wah Kiu, Boris Reznik, Piper Weldy, Salha S. Daniel and Raymond I. Stark
      Drug Metabolism and Disposition April 2006, 34 (4) 636-646; DOI: https://doi.org/10.1124/dmd.105.007567

  3. Alander, Sarah W.

    1. CYP2D6*36 GENE ARRANGEMENTS WITHIN THE CYP2D6 LOCUS: ASSOCIATION OF CYP2D6*36 WITH POOR METABOLIZER STATUS
      Andrea Gaedigk, L. DiAnne Bradford, Sarah W. Alander and J. Steven Leeder
      Drug Metabolism and Disposition April 2006, 34 (4) 563-569; DOI: https://doi.org/10.1124/dmd.105.008292

  4. Álvarez, Ana I.

    1. BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2) TRANSPORTS FLUOROQUINOLONE ANTIBIOTICS AND AFFECTS THEIR ORAL AVAILABILITY, PHARMACOKINETICS, AND MILK SECRETION
      Gracia Merino, Ana I. Álvarez, Mivis M. Pulido, Antonio J. Molina, Alfred H. Schinkel and Julio G. Prieto
      Drug Metabolism and Disposition April 2006, 34 (4) 690-695; DOI: https://doi.org/10.1124/dmd.105.008219

  5. Anderson, Bradley D.

    1. DEPENDENCE OF NELFINAVIR BRAIN UPTAKE ON DOSE AND TISSUE CONCENTRATIONS OF THE SELECTIVE P-GLYCOPROTEIN INHIBITOR ZOSUQUIDAR IN RATS
      Bradley D. Anderson, Melissa J. May, Sherri Jordan, Lin Song, Michael J. Roberts and Markos Leggas
      Drug Metabolism and Disposition April 2006, 34 (4) 653-659; DOI: https://doi.org/10.1124/dmd.105.006536

  6. Anderson, Gail D.

    1. INTERACTIONS OF AMOXICILLIN AND CEFACLOR WITH HUMAN RENAL ORGANIC ANION AND PEPTIDE TRANSPORTERS
      Meng Li, Gail D. Anderson, Brian R. Phillips, Wei Kong, Danny D. Shen and Joanne Wang
      Drug Metabolism and Disposition April 2006, 34 (4) 547-555; DOI: https://doi.org/10.1124/dmd.105.006791

  7. Arroyo, Sylvia E.

    1. FETAL MORPHINE METABOLISM AND CLEARANCE ARE CONSTANT DURING LATE GESTATION
      Marianne Garland, Kirsten M. Abildskov, Samantha Taylor, Kenza Benzeroual, Casper S. Caspersen, Sylvia E. Arroyo, Tung-wah Kiu, Boris Reznik, Piper Weldy, Salha S. Daniel and Raymond I. Stark
      Drug Metabolism and Disposition April 2006, 34 (4) 636-646; DOI: https://doi.org/10.1124/dmd.105.007567

  8. Austin, R. P.

    1. RESPONSE TO “BINDING OF DRUGS TO HEPATIC MICROSOMES: COMMENT AND ASSESSMENT OF CURRENT PREDICTION METHODOLOGY WITH RECOMMENDATION FOR IMPROVEMENT”
      R. P. Austin, P. Barton and R. J. Riley
      Drug Metabolism and Disposition April 2006, 34 (4) 727; DOI: https://doi.org/10.1124/dmd.105.009142

B

  1. Backes, Wayne L.

    1. AN EVALUATION OF METHODS FOR THE RECONSTITUTION OF CYTOCHROMES P450 AND NADPH P450 REDUCTASE INTO LIPID VESICLES
      James R. Reed, Rusty W. Kelley and Wayne L. Backes
      Drug Metabolism and Disposition April 2006, 34 (4) 660-666; DOI: https://doi.org/10.1124/dmd.105.006825

  2. Barton, P.

    1. RESPONSE TO “BINDING OF DRUGS TO HEPATIC MICROSOMES: COMMENT AND ASSESSMENT OF CURRENT PREDICTION METHODOLOGY WITH RECOMMENDATION FOR IMPROVEMENT”
      R. P. Austin, P. Barton and R. J. Riley
      Drug Metabolism and Disposition April 2006, 34 (4) 727; DOI: https://doi.org/10.1124/dmd.105.009142

  3. Benzeroual, Kenza

    1. FETAL MORPHINE METABOLISM AND CLEARANCE ARE CONSTANT DURING LATE GESTATION
      Marianne Garland, Kirsten M. Abildskov, Samantha Taylor, Kenza Benzeroual, Casper S. Caspersen, Sylvia E. Arroyo, Tung-wah Kiu, Boris Reznik, Piper Weldy, Salha S. Daniel and Raymond I. Stark
      Drug Metabolism and Disposition April 2006, 34 (4) 636-646; DOI: https://doi.org/10.1124/dmd.105.007567

  4. Bier, Dirk

    1. METABOLISM OF THE A1 ADENOSINE RECEPTOR POSITRON EMISSION TOMOGRAPHY LIGAND [18F]8-CYCLOPENTYL-3-(3-FLUOROPROPYL)-1-PROPYLXANTHINE ([18F]CPFPX) IN RODENTS AND HUMANS
      Dirk Bier, Marcus H. Holschbach, Walter Wutz, Ray A. Olsson and Heinz H. Coenen
      Drug Metabolism and Disposition April 2006, 34 (4) 570-576; DOI: https://doi.org/10.1124/dmd.105.006411

  5. Biot, Christophe

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  6. Bourrié, Martine

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  7. Bowlin, Stephen

    1. IN VITRO METABOLIC ACTIVATION OF THIABENDAZOLE VIA 5-HYDROXYTHIABENDAZOLE: IDENTIFICATION OF A GLUTATHIONE CONJUGATE OF 5-HYDROXYTHIABENDAZOLE
      Deepak Dalvie, Evan Smith, Alan Deese and Stephen Bowlin
      Drug Metabolism and Disposition April 2006, 34 (4) 709-717; DOI: https://doi.org/10.1124/dmd.105.008094

  8. Bradford, L. DiAnne

    1. CYP2D6*36 GENE ARRANGEMENTS WITHIN THE CYP2D6 LOCUS: ASSOCIATION OF CYP2D6*36 WITH POOR METABOLIZER STATUS
      Andrea Gaedigk, L. DiAnne Bradford, Sarah W. Alander and J. Steven Leeder
      Drug Metabolism and Disposition April 2006, 34 (4) 563-569; DOI: https://doi.org/10.1124/dmd.105.008292

  9. Brocard, Jacques

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  10. Brouwer, Kim L. R.

    1. CHARACTERIZATION OF TRANSPORT PROTEIN EXPRESSION IN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN (MRP) 2-DEFICIENT RATS
      Brendan M. Johnson, Peijin Zhang, John D. Schuetz and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2006, 34 (4) 556-562; DOI: https://doi.org/10.1124/dmd.105.005793
    2. ALTERED HEPATOBILIARY DISPOSITION OF 5 (AND 6)-CARBOXY-2′,7′-DICHLOROFLUORESCEIN IN Abcg2 (Bcrp1) AND Abcc2 (Mrp2) KNOCKOUT MICE
      Ken-ichi Nezasa, Xianbin Tian, Maciej J. Zamek-Gliszczynski, Nita J. Patel, Thomas J. Raub and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2006, 34 (4) 718-723; DOI: https://doi.org/10.1124/dmd.105.007922

  11. Brown, Simon

    1. IN SILICO AND IN VITRO SCREENING FOR INHIBITION OF CYTOCHROME P450 CYP3A4 BY COMEDICATIONS COMMONLY USED BY PATIENTS WITH CANCER
      Jean-Didier Marechal, Jinglei Yu, Simon Brown, Iouri Kapelioukh, Elaine M. Rankin, C. Roland Wolf, Gordon C. K. Roberts, Mark. J. I. Paine and Michael J. Sutcliffe
      Drug Metabolism and Disposition April 2006, 34 (4) 534-538; DOI: https://doi.org/10.1124/dmd.105.007625

C

  1. Camacho, Raquel

    1. EMPIRICAL VALIDATION OF A RAT IN VITRO ORGAN SLICE MODEL AS A TOOL FOR IN VIVO CLEARANCE PREDICTION
      Inge A. M. de Graaf, Ruben de Kanter, Marina H. de Jager, Raquel Camacho, Elise Langenkamp, Esther G. van de Kerkhof and Geny M. M. Groothuis
      Drug Metabolism and Disposition April 2006, 34 (4) 591-599; DOI: https://doi.org/10.1124/dmd.105.006726

  2. Caspersen, Casper S.

    1. FETAL MORPHINE METABOLISM AND CLEARANCE ARE CONSTANT DURING LATE GESTATION
      Marianne Garland, Kirsten M. Abildskov, Samantha Taylor, Kenza Benzeroual, Casper S. Caspersen, Sylvia E. Arroyo, Tung-wah Kiu, Boris Reznik, Piper Weldy, Salha S. Daniel and Raymond I. Stark
      Drug Metabolism and Disposition April 2006, 34 (4) 636-646; DOI: https://doi.org/10.1124/dmd.105.007567

  3. Cha, In-June

    1. INHIBITORY EFFECTS OF FRUIT JUICES ON CYP3A ACTIVITY
      Hyunmi Kim, Yune-Jung Yoon, Ji-Hong Shon, In-June Cha, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition April 2006, 34 (4) 521-523; DOI: https://doi.org/10.1124/dmd.105.007930

  4. Chiron, Catherine

    1. IN VITRO AND IN VIVO INHIBITORY EFFECT OF STIRIPENTOL ON CLOBAZAM METABOLISM
      Carole Giraud, Jean-Marc Treluyer, Elisabeth Rey, Catherine Chiron, Jean Vincent, Gérard Pons and Agnès Tran
      Drug Metabolism and Disposition April 2006, 34 (4) 608-611; DOI: https://doi.org/10.1124/dmd.105.007237

  5. Chowdhury, Swapan K.

    1. IDENTIFICATION OF HUMAN LIVER CYTOCHROME P450 ENZYMES RESPONSIBLE FOR THE METABOLISM OF LONAFARNIB (SARASAR)
      Anima Ghosal, Swapan K. Chowdhury, Wei Tong, Neil Hapangama, Yuan Yuan, Ai-Duen Su and Shmuel Zbaida
      Drug Metabolism and Disposition April 2006, 34 (4) 628-635; DOI: https://doi.org/10.1124/dmd.105.007906

  6. Coenen, Heinz H.

    1. METABOLISM OF THE A1 ADENOSINE RECEPTOR POSITRON EMISSION TOMOGRAPHY LIGAND [18F]8-CYCLOPENTYL-3-(3-FLUOROPROPYL)-1-PROPYLXANTHINE ([18F]CPFPX) IN RODENTS AND HUMANS
      Dirk Bier, Marcus H. Holschbach, Walter Wutz, Ray A. Olsson and Heinz H. Coenen
      Drug Metabolism and Disposition April 2006, 34 (4) 570-576; DOI: https://doi.org/10.1124/dmd.105.006411

  7. Cole, Susan P. C.

    1. MUTATIONAL ANALYSIS OF POLAR AMINO ACID RESIDUES WITHIN PREDICTED TRANSMEMBRANE HELICES 10 AND 16 OF MULTIDRUG RESISTANCE PROTEIN 1 (ABCC1): EFFECT ON SUBSTRATE SPECIFICITY
      Da-Wei Zhang, Kenichi Nunoya, Monika Vasa, Hong-Mei Gu, Susan P. C. Cole and Roger G. Deeley
      Drug Metabolism and Disposition April 2006, 34 (4) 539-546; DOI: https://doi.org/10.1124/dmd.105.007740

D

  1. Daher, Wassim

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  2. Dalvie, Deepak

    1. IN VITRO METABOLIC ACTIVATION OF THIABENDAZOLE VIA 5-HYDROXYTHIABENDAZOLE: IDENTIFICATION OF A GLUTATHIONE CONJUGATE OF 5-HYDROXYTHIABENDAZOLE
      Deepak Dalvie, Evan Smith, Alan Deese and Stephen Bowlin
      Drug Metabolism and Disposition April 2006, 34 (4) 709-717; DOI: https://doi.org/10.1124/dmd.105.008094

  3. Daniel, Salha S.

    1. FETAL MORPHINE METABOLISM AND CLEARANCE ARE CONSTANT DURING LATE GESTATION
      Marianne Garland, Kirsten M. Abildskov, Samantha Taylor, Kenza Benzeroual, Casper S. Caspersen, Sylvia E. Arroyo, Tung-wah Kiu, Boris Reznik, Piper Weldy, Salha S. Daniel and Raymond I. Stark
      Drug Metabolism and Disposition April 2006, 34 (4) 636-646; DOI: https://doi.org/10.1124/dmd.105.007567

  4. Deeley, Roger G.

    1. MUTATIONAL ANALYSIS OF POLAR AMINO ACID RESIDUES WITHIN PREDICTED TRANSMEMBRANE HELICES 10 AND 16 OF MULTIDRUG RESISTANCE PROTEIN 1 (ABCC1): EFFECT ON SUBSTRATE SPECIFICITY
      Da-Wei Zhang, Kenichi Nunoya, Monika Vasa, Hong-Mei Gu, Susan P. C. Cole and Roger G. Deeley
      Drug Metabolism and Disposition April 2006, 34 (4) 539-546; DOI: https://doi.org/10.1124/dmd.105.007740

  5. Deese, Alan

    1. IN VITRO METABOLIC ACTIVATION OF THIABENDAZOLE VIA 5-HYDROXYTHIABENDAZOLE: IDENTIFICATION OF A GLUTATHIONE CONJUGATE OF 5-HYDROXYTHIABENDAZOLE
      Deepak Dalvie, Evan Smith, Alan Deese and Stephen Bowlin
      Drug Metabolism and Disposition April 2006, 34 (4) 709-717; DOI: https://doi.org/10.1124/dmd.105.008094

  6. de Graaf, Inge A. M.

    1. EMPIRICAL VALIDATION OF A RAT IN VITRO ORGAN SLICE MODEL AS A TOOL FOR IN VIVO CLEARANCE PREDICTION
      Inge A. M. de Graaf, Ruben de Kanter, Marina H. de Jager, Raquel Camacho, Elise Langenkamp, Esther G. van de Kerkhof and Geny M. M. Groothuis
      Drug Metabolism and Disposition April 2006, 34 (4) 591-599; DOI: https://doi.org/10.1124/dmd.105.006726

  7. de Jager, Marina H.

    1. EMPIRICAL VALIDATION OF A RAT IN VITRO ORGAN SLICE MODEL AS A TOOL FOR IN VIVO CLEARANCE PREDICTION
      Inge A. M. de Graaf, Ruben de Kanter, Marina H. de Jager, Raquel Camacho, Elise Langenkamp, Esther G. van de Kerkhof and Geny M. M. Groothuis
      Drug Metabolism and Disposition April 2006, 34 (4) 591-599; DOI: https://doi.org/10.1124/dmd.105.006726

  8. de Kanter, Ruben

    1. EMPIRICAL VALIDATION OF A RAT IN VITRO ORGAN SLICE MODEL AS A TOOL FOR IN VIVO CLEARANCE PREDICTION
      Inge A. M. de Graaf, Ruben de Kanter, Marina H. de Jager, Raquel Camacho, Elise Langenkamp, Esther G. van de Kerkhof and Geny M. M. Groothuis
      Drug Metabolism and Disposition April 2006, 34 (4) 591-599; DOI: https://doi.org/10.1124/dmd.105.006726

  9. Dive, Daniel

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  10. Dreisbach, Annette

    1. EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)
      Henriette E. Meyer zu Schwabedissen, Markus Grube, Annette Dreisbach, Gabriele Jedlitschky, Konrad Meissner, Knud Linnemann, Christoph Fusch, Christoph A. Ritter, Uwe Völker and Heyo K. Kroemer
      Drug Metabolism and Disposition April 2006, 34 (4) 524-533; DOI: https://doi.org/10.1124/dmd.105.007591

E

  1. Eckstein, James A.

    1. INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450
      Jessica L. Fayer Rehmel, James A. Eckstein, Nagy A. Farid, John B. Heim, Steve C. Kasper, Atsushi Kurihara, Steven A. Wrighton and Barbara J. Ring
      Drug Metabolism and Disposition April 2006, 34 (4) 600-607; DOI: https://doi.org/10.1124/dmd.105.007989

  2. Eikel, Daniel

    1. S-2-PENTYL-4-PENTYNOIC HYDROXAMIC ACID AND ITS METABOLITE S-2-PENTYL-4-PENTYNOIC ACID IN THE NMRI-EXENCEPHALY-MOUSE MODEL: PHARMACOKINETIC PROFILES, TERATOGENIC EFFECTS, AND HISTONE DEACETYLASE INHIBITION ABILITIES OF FURTHER VALPROIC ACID HYDROXAMATES AND AMIDES
      Daniel Eikel, Katrin Hoffmann, Karolin Zoll, Alfonso Lampen and Heinz Nau
      Drug Metabolism and Disposition April 2006, 34 (4) 612-620; DOI: https://doi.org/10.1124/dmd.105.008078

F

  1. Fabre, Gérard

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  2. Farid, Nagy A.

    1. INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450
      Jessica L. Fayer Rehmel, James A. Eckstein, Nagy A. Farid, John B. Heim, Steve C. Kasper, Atsushi Kurihara, Steven A. Wrighton and Barbara J. Ring
      Drug Metabolism and Disposition April 2006, 34 (4) 600-607; DOI: https://doi.org/10.1124/dmd.105.007989

  3. Fraisse, Laurent

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  4. Fuchikami, Hiromi

    1. EFFECTS OF HERBAL EXTRACTS ON THE FUNCTION OF HUMAN ORGANIC ANION-TRANSPORTING POLYPEPTIDE OATP-B
      Hiromi Fuchikami, Hiroki Satoh, Masayuki Tsujimoto, Shigehiro Ohdo, Hisakazu Ohtani and Yasufumi Sawada
      Drug Metabolism and Disposition April 2006, 34 (4) 577-582; DOI: https://doi.org/10.1124/dmd.105.007872

  5. Fusch, Christoph

    1. EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)
      Henriette E. Meyer zu Schwabedissen, Markus Grube, Annette Dreisbach, Gabriele Jedlitschky, Konrad Meissner, Knud Linnemann, Christoph Fusch, Christoph A. Ritter, Uwe Völker and Heyo K. Kroemer
      Drug Metabolism and Disposition April 2006, 34 (4) 524-533; DOI: https://doi.org/10.1124/dmd.105.007591

G

  1. Gaedigk, Andrea

    1. CYP2D6*36 GENE ARRANGEMENTS WITHIN THE CYP2D6 LOCUS: ASSOCIATION OF CYP2D6*36 WITH POOR METABOLIZER STATUS
      Andrea Gaedigk, L. DiAnne Bradford, Sarah W. Alander and J. Steven Leeder
      Drug Metabolism and Disposition April 2006, 34 (4) 563-569; DOI: https://doi.org/10.1124/dmd.105.008292

  2. Gallegos, Richard

    1. INVESTIGATION OF DRUG-DRUG INTERACTION POTENTIAL OF BORTEZOMIB IN VIVO IN FEMALE SPRAGUE-DAWLEY RATS AND IN VITRO IN HUMAN LIVER MICROSOMES
      Chuang Lu, Richard Gallegos, Ping Li, Cindy Q. Xia, Sandeepraj Pusalkar, Vinita Uttamsingh, Darrell Nix, Gerald T. Miwa and Liang-Shang Gan
      Drug Metabolism and Disposition April 2006, 34 (4) 702-708; DOI: https://doi.org/10.1124/dmd.105.008060

  3. Gan, Liang-Shang

    1. INVESTIGATION OF DRUG-DRUG INTERACTION POTENTIAL OF BORTEZOMIB IN VIVO IN FEMALE SPRAGUE-DAWLEY RATS AND IN VITRO IN HUMAN LIVER MICROSOMES
      Chuang Lu, Richard Gallegos, Ping Li, Cindy Q. Xia, Sandeepraj Pusalkar, Vinita Uttamsingh, Darrell Nix, Gerald T. Miwa and Liang-Shang Gan
      Drug Metabolism and Disposition April 2006, 34 (4) 702-708; DOI: https://doi.org/10.1124/dmd.105.008060

  4. Garland, Marianne

    1. FETAL MORPHINE METABOLISM AND CLEARANCE ARE CONSTANT DURING LATE GESTATION
      Marianne Garland, Kirsten M. Abildskov, Samantha Taylor, Kenza Benzeroual, Casper S. Caspersen, Sylvia E. Arroyo, Tung-wah Kiu, Boris Reznik, Piper Weldy, Salha S. Daniel and Raymond I. Stark
      Drug Metabolism and Disposition April 2006, 34 (4) 636-646; DOI: https://doi.org/10.1124/dmd.105.007567

  5. Ghosal, Anima

    1. IDENTIFICATION OF HUMAN LIVER CYTOCHROME P450 ENZYMES RESPONSIBLE FOR THE METABOLISM OF LONAFARNIB (SARASAR)
      Anima Ghosal, Swapan K. Chowdhury, Wei Tong, Neil Hapangama, Yuan Yuan, Ai-Duen Su and Shmuel Zbaida
      Drug Metabolism and Disposition April 2006, 34 (4) 628-635; DOI: https://doi.org/10.1124/dmd.105.007906

  6. Giraud, Carole

    1. IN VITRO AND IN VIVO INHIBITORY EFFECT OF STIRIPENTOL ON CLOBAZAM METABOLISM
      Carole Giraud, Jean-Marc Treluyer, Elisabeth Rey, Catherine Chiron, Jean Vincent, Gérard Pons and Agnès Tran
      Drug Metabolism and Disposition April 2006, 34 (4) 608-611; DOI: https://doi.org/10.1124/dmd.105.007237

  7. Groothuis, Geny M. M.

    1. EMPIRICAL VALIDATION OF A RAT IN VITRO ORGAN SLICE MODEL AS A TOOL FOR IN VIVO CLEARANCE PREDICTION
      Inge A. M. de Graaf, Ruben de Kanter, Marina H. de Jager, Raquel Camacho, Elise Langenkamp, Esther G. van de Kerkhof and Geny M. M. Groothuis
      Drug Metabolism and Disposition April 2006, 34 (4) 591-599; DOI: https://doi.org/10.1124/dmd.105.006726

  8. Grube, Markus

    1. EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)
      Henriette E. Meyer zu Schwabedissen, Markus Grube, Annette Dreisbach, Gabriele Jedlitschky, Konrad Meissner, Knud Linnemann, Christoph Fusch, Christoph A. Ritter, Uwe Völker and Heyo K. Kroemer
      Drug Metabolism and Disposition April 2006, 34 (4) 524-533; DOI: https://doi.org/10.1124/dmd.105.007591

  9. Gu, Hong-Mei

    1. MUTATIONAL ANALYSIS OF POLAR AMINO ACID RESIDUES WITHIN PREDICTED TRANSMEMBRANE HELICES 10 AND 16 OF MULTIDRUG RESISTANCE PROTEIN 1 (ABCC1): EFFECT ON SUBSTRATE SPECIFICITY
      Da-Wei Zhang, Kenichi Nunoya, Monika Vasa, Hong-Mei Gu, Susan P. C. Cole and Roger G. Deeley
      Drug Metabolism and Disposition April 2006, 34 (4) 539-546; DOI: https://doi.org/10.1124/dmd.105.007740

  10. Guillou, François

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

H

  1. Hallifax, David

    1. BINDING OF DRUGS TO HEPATIC MICROSOMES: COMMENT AND ASSESSMENT OF CURRENT PREDICTION METHODOLOGY WITH RECOMMENDATION FOR IMPROVEMENT
      David Hallifax and J. Brian Houston
      Drug Metabolism and Disposition April 2006, 34 (4) 724-726; DOI: https://doi.org/10.1124/dmd.105.007658

  2. Hapangama, Neil

    1. IDENTIFICATION OF HUMAN LIVER CYTOCHROME P450 ENZYMES RESPONSIBLE FOR THE METABOLISM OF LONAFARNIB (SARASAR)
      Anima Ghosal, Swapan K. Chowdhury, Wei Tong, Neil Hapangama, Yuan Yuan, Ai-Duen Su and Shmuel Zbaida
      Drug Metabolism and Disposition April 2006, 34 (4) 628-635; DOI: https://doi.org/10.1124/dmd.105.007906

  3. Hashikura, Yasuhiko

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  4. Heim, John B.

    1. INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450
      Jessica L. Fayer Rehmel, James A. Eckstein, Nagy A. Farid, John B. Heim, Steve C. Kasper, Atsushi Kurihara, Steven A. Wrighton and Barbara J. Ring
      Drug Metabolism and Disposition April 2006, 34 (4) 600-607; DOI: https://doi.org/10.1124/dmd.105.007989

  5. Hoffmann, Katrin

    1. S-2-PENTYL-4-PENTYNOIC HYDROXAMIC ACID AND ITS METABOLITE S-2-PENTYL-4-PENTYNOIC ACID IN THE NMRI-EXENCEPHALY-MOUSE MODEL: PHARMACOKINETIC PROFILES, TERATOGENIC EFFECTS, AND HISTONE DEACETYLASE INHIBITION ABILITIES OF FURTHER VALPROIC ACID HYDROXAMATES AND AMIDES
      Daniel Eikel, Katrin Hoffmann, Karolin Zoll, Alfonso Lampen and Heinz Nau
      Drug Metabolism and Disposition April 2006, 34 (4) 612-620; DOI: https://doi.org/10.1124/dmd.105.008078

  6. Holschbach, Marcus H.

    1. METABOLISM OF THE A1 ADENOSINE RECEPTOR POSITRON EMISSION TOMOGRAPHY LIGAND [18F]8-CYCLOPENTYL-3-(3-FLUOROPROPYL)-1-PROPYLXANTHINE ([18F]CPFPX) IN RODENTS AND HUMANS
      Dirk Bier, Marcus H. Holschbach, Walter Wutz, Ray A. Olsson and Heinz H. Coenen
      Drug Metabolism and Disposition April 2006, 34 (4) 570-576; DOI: https://doi.org/10.1124/dmd.105.006411

  7. Houston, J. Brian

    1. BINDING OF DRUGS TO HEPATIC MICROSOMES: COMMENT AND ASSESSMENT OF CURRENT PREDICTION METHODOLOGY WITH RECOMMENDATION FOR IMPROVEMENT
      David Hallifax and J. Brian Houston
      Drug Metabolism and Disposition April 2006, 34 (4) 724-726; DOI: https://doi.org/10.1124/dmd.105.007658

I

  1. Inada, Yoichi

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  2. Isoherranen, Nina

    1. STEREOCHEMICAL ASPECTS OF ITRACONAZOLE METABOLISM IN VITRO AND IN VIVO
      Kent L. Kunze, Wendel L. Nelson, Evan D. Kharasch, Kenneth E. Thummel and Nina Isoherranen
      Drug Metabolism and Disposition April 2006, 34 (4) 583-590; DOI: https://doi.org/10.1124/dmd.105.008508

J

  1. Jedlitschky, Gabriele

    1. EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)
      Henriette E. Meyer zu Schwabedissen, Markus Grube, Annette Dreisbach, Gabriele Jedlitschky, Konrad Meissner, Knud Linnemann, Christoph Fusch, Christoph A. Ritter, Uwe Völker and Heyo K. Kroemer
      Drug Metabolism and Disposition April 2006, 34 (4) 524-533; DOI: https://doi.org/10.1124/dmd.105.007591

  2. Johnson, Brendan M.

    1. CHARACTERIZATION OF TRANSPORT PROTEIN EXPRESSION IN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN (MRP) 2-DEFICIENT RATS
      Brendan M. Johnson, Peijin Zhang, John D. Schuetz and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2006, 34 (4) 556-562; DOI: https://doi.org/10.1124/dmd.105.005793

  3. Jordan, Sherri

    1. DEPENDENCE OF NELFINAVIR BRAIN UPTAKE ON DOSE AND TISSUE CONCENTRATIONS OF THE SELECTIVE P-GLYCOPROTEIN INHIBITOR ZOSUQUIDAR IN RATS
      Bradley D. Anderson, Melissa J. May, Sherri Jordan, Lin Song, Michael J. Roberts and Markos Leggas
      Drug Metabolism and Disposition April 2006, 34 (4) 653-659; DOI: https://doi.org/10.1124/dmd.105.006536

  4. Joshi, Meenal

    1. INDUCTION AND RECOVERY TIME COURSE OF RAT BRAIN CYP2E1 AFTER NICOTINE TREATMENT
      Meenal Joshi and Rachel F. Tyndale
      Drug Metabolism and Disposition April 2006, 34 (4) 647-652; DOI: https://doi.org/10.1124/dmd.105.008029

K

  1. Kamiyoshi, Akiko

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  2. Kapelioukh, Iouri

    1. IN SILICO AND IN VITRO SCREENING FOR INHIBITION OF CYTOCHROME P450 CYP3A4 BY COMEDICATIONS COMMONLY USED BY PATIENTS WITH CANCER
      Jean-Didier Marechal, Jinglei Yu, Simon Brown, Iouri Kapelioukh, Elaine M. Rankin, C. Roland Wolf, Gordon C. K. Roberts, Mark. J. I. Paine and Michael J. Sutcliffe
      Drug Metabolism and Disposition April 2006, 34 (4) 534-538; DOI: https://doi.org/10.1124/dmd.105.007625

  3. Karnes, Thomas H.

    1. EFFECT OF CHRONIC RENAL INSUFFICIENCY ON HEPATIC AND RENAL UDP-GLUCURONYLTRANSFERASES IN RATS
      Chuanhui Yu, Joseph K. Ritter, Richard J. Krieg, Bhaskar Rege, Thomas H. Karnes and Mohamadi A. Sarkar
      Drug Metabolism and Disposition April 2006, 34 (4) 621-627; DOI: https://doi.org/10.1124/dmd.105.006601

  4. Kasper, Steve C.

    1. INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450
      Jessica L. Fayer Rehmel, James A. Eckstein, Nagy A. Farid, John B. Heim, Steve C. Kasper, Atsushi Kurihara, Steven A. Wrighton and Barbara J. Ring
      Drug Metabolism and Disposition April 2006, 34 (4) 600-607; DOI: https://doi.org/10.1124/dmd.105.007989

  5. Kelley, Rusty W.

    1. AN EVALUATION OF METHODS FOR THE RECONSTITUTION OF CYTOCHROMES P450 AND NADPH P450 REDUCTASE INTO LIPID VESICLES
      James R. Reed, Rusty W. Kelley and Wayne L. Backes
      Drug Metabolism and Disposition April 2006, 34 (4) 660-666; DOI: https://doi.org/10.1124/dmd.105.006825

  6. Khalife, Jamal

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  7. Kharasch, Evan D.

    1. STEREOCHEMICAL ASPECTS OF ITRACONAZOLE METABOLISM IN VITRO AND IN VIVO
      Kent L. Kunze, Wendel L. Nelson, Evan D. Kharasch, Kenneth E. Thummel and Nina Isoherranen
      Drug Metabolism and Disposition April 2006, 34 (4) 583-590; DOI: https://doi.org/10.1124/dmd.105.008508

  8. Kim, Hyunmi

    1. INHIBITORY EFFECTS OF FRUIT JUICES ON CYP3A ACTIVITY
      Hyunmi Kim, Yune-Jung Yoon, Ji-Hong Shon, In-June Cha, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition April 2006, 34 (4) 521-523; DOI: https://doi.org/10.1124/dmd.105.007930

  9. Kim, Sang K.

    1. THE MITOGEN-ACTIVATED PROTEIN KINASE KINASE (MEK) INHIBITOR PD98059 ELEVATES PRIMARY CULTURED RAT HEPATOCYTE GLUTATHIONE LEVELS INDEPENDENT OF INHIBITING MEK
      Sang K. Kim, Mohamed A. Abdelmegeed and Raymond F. Novak
      Drug Metabolism and Disposition April 2006, 34 (4) 683-689; DOI: https://doi.org/10.1124/dmd.105.007666

  10. Kishida, Tomoyuki

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  11. Kiu, Tung-wah

    1. FETAL MORPHINE METABOLISM AND CLEARANCE ARE CONSTANT DURING LATE GESTATION
      Marianne Garland, Kirsten M. Abildskov, Samantha Taylor, Kenza Benzeroual, Casper S. Caspersen, Sylvia E. Arroyo, Tung-wah Kiu, Boris Reznik, Piper Weldy, Salha S. Daniel and Raymond I. Stark
      Drug Metabolism and Disposition April 2006, 34 (4) 636-646; DOI: https://doi.org/10.1124/dmd.105.007567

  12. Klieber, Sylvie

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  13. Kong, Wei

    1. INTERACTIONS OF AMOXICILLIN AND CEFACLOR WITH HUMAN RENAL ORGANIC ANION AND PEPTIDE TRANSPORTERS
      Meng Li, Gail D. Anderson, Brian R. Phillips, Wei Kong, Danny D. Shen and Joanne Wang
      Drug Metabolism and Disposition April 2006, 34 (4) 547-555; DOI: https://doi.org/10.1124/dmd.105.006791

  14. Krieg, Richard J.

    1. EFFECT OF CHRONIC RENAL INSUFFICIENCY ON HEPATIC AND RENAL UDP-GLUCURONYLTRANSFERASES IN RATS
      Chuanhui Yu, Joseph K. Ritter, Richard J. Krieg, Bhaskar Rege, Thomas H. Karnes and Mohamadi A. Sarkar
      Drug Metabolism and Disposition April 2006, 34 (4) 621-627; DOI: https://doi.org/10.1124/dmd.105.006601

  15. Kroemer, Heyo K.

    1. EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)
      Henriette E. Meyer zu Schwabedissen, Markus Grube, Annette Dreisbach, Gabriele Jedlitschky, Konrad Meissner, Knud Linnemann, Christoph Fusch, Christoph A. Ritter, Uwe Völker and Heyo K. Kroemer
      Drug Metabolism and Disposition April 2006, 34 (4) 524-533; DOI: https://doi.org/10.1124/dmd.105.007591

  16. Kunze, Kent L.

    1. STEREOCHEMICAL ASPECTS OF ITRACONAZOLE METABOLISM IN VITRO AND IN VIVO
      Kent L. Kunze, Wendel L. Nelson, Evan D. Kharasch, Kenneth E. Thummel and Nina Isoherranen
      Drug Metabolism and Disposition April 2006, 34 (4) 583-590; DOI: https://doi.org/10.1124/dmd.105.008508

  17. Kurihara, Atsushi

    1. INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450
      Jessica L. Fayer Rehmel, James A. Eckstein, Nagy A. Farid, John B. Heim, Steve C. Kasper, Atsushi Kurihara, Steven A. Wrighton and Barbara J. Ring
      Drug Metabolism and Disposition April 2006, 34 (4) 600-607; DOI: https://doi.org/10.1124/dmd.105.007989

  18. Kuroda, Junji

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

L

  1. Lampen, Alfonso

    1. S-2-PENTYL-4-PENTYNOIC HYDROXAMIC ACID AND ITS METABOLITE S-2-PENTYL-4-PENTYNOIC ACID IN THE NMRI-EXENCEPHALY-MOUSE MODEL: PHARMACOKINETIC PROFILES, TERATOGENIC EFFECTS, AND HISTONE DEACETYLASE INHIBITION ABILITIES OF FURTHER VALPROIC ACID HYDROXAMATES AND AMIDES
      Daniel Eikel, Katrin Hoffmann, Karolin Zoll, Alfonso Lampen and Heinz Nau
      Drug Metabolism and Disposition April 2006, 34 (4) 612-620; DOI: https://doi.org/10.1124/dmd.105.008078

  2. Langenkamp, Elise

    1. EMPIRICAL VALIDATION OF A RAT IN VITRO ORGAN SLICE MODEL AS A TOOL FOR IN VIVO CLEARANCE PREDICTION
      Inge A. M. de Graaf, Ruben de Kanter, Marina H. de Jager, Raquel Camacho, Elise Langenkamp, Esther G. van de Kerkhof and Geny M. M. Groothuis
      Drug Metabolism and Disposition April 2006, 34 (4) 591-599; DOI: https://doi.org/10.1124/dmd.105.006726

  3. Leeder, J. Steven

    1. CYP2D6*36 GENE ARRANGEMENTS WITHIN THE CYP2D6 LOCUS: ASSOCIATION OF CYP2D6*36 WITH POOR METABOLIZER STATUS
      Andrea Gaedigk, L. DiAnne Bradford, Sarah W. Alander and J. Steven Leeder
      Drug Metabolism and Disposition April 2006, 34 (4) 563-569; DOI: https://doi.org/10.1124/dmd.105.008292

  4. Leggas, Markos

    1. DEPENDENCE OF NELFINAVIR BRAIN UPTAKE ON DOSE AND TISSUE CONCENTRATIONS OF THE SELECTIVE P-GLYCOPROTEIN INHIBITOR ZOSUQUIDAR IN RATS
      Bradley D. Anderson, Melissa J. May, Sherri Jordan, Lin Song, Michael J. Roberts and Markos Leggas
      Drug Metabolism and Disposition April 2006, 34 (4) 653-659; DOI: https://doi.org/10.1124/dmd.105.006536

  5. Li, Meng

    1. INTERACTIONS OF AMOXICILLIN AND CEFACLOR WITH HUMAN RENAL ORGANIC ANION AND PEPTIDE TRANSPORTERS
      Meng Li, Gail D. Anderson, Brian R. Phillips, Wei Kong, Danny D. Shen and Joanne Wang
      Drug Metabolism and Disposition April 2006, 34 (4) 547-555; DOI: https://doi.org/10.1124/dmd.105.006791

  6. Li, Ping

    1. INVESTIGATION OF DRUG-DRUG INTERACTION POTENTIAL OF BORTEZOMIB IN VIVO IN FEMALE SPRAGUE-DAWLEY RATS AND IN VITRO IN HUMAN LIVER MICROSOMES
      Chuang Lu, Richard Gallegos, Ping Li, Cindy Q. Xia, Sandeepraj Pusalkar, Vinita Uttamsingh, Darrell Nix, Gerald T. Miwa and Liang-Shang Gan
      Drug Metabolism and Disposition April 2006, 34 (4) 702-708; DOI: https://doi.org/10.1124/dmd.105.008060

  7. Linnemann, Knud

    1. EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)
      Henriette E. Meyer zu Schwabedissen, Markus Grube, Annette Dreisbach, Gabriele Jedlitschky, Konrad Meissner, Knud Linnemann, Christoph Fusch, Christoph A. Ritter, Uwe Völker and Heyo K. Kroemer
      Drug Metabolism and Disposition April 2006, 34 (4) 524-533; DOI: https://doi.org/10.1124/dmd.105.007591

  8. Liu, Kwang-Hyeon

    1. INHIBITORY EFFECTS OF FRUIT JUICES ON CYP3A ACTIVITY
      Hyunmi Kim, Yune-Jung Yoon, Ji-Hong Shon, In-June Cha, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition April 2006, 34 (4) 521-523; DOI: https://doi.org/10.1124/dmd.105.007930

  9. Lu, Chuang

    1. INVESTIGATION OF DRUG-DRUG INTERACTION POTENTIAL OF BORTEZOMIB IN VIVO IN FEMALE SPRAGUE-DAWLEY RATS AND IN VITRO IN HUMAN LIVER MICROSOMES
      Chuang Lu, Richard Gallegos, Ping Li, Cindy Q. Xia, Sandeepraj Pusalkar, Vinita Uttamsingh, Darrell Nix, Gerald T. Miwa and Liang-Shang Gan
      Drug Metabolism and Disposition April 2006, 34 (4) 702-708; DOI: https://doi.org/10.1124/dmd.105.008060

M

  1. Maffrand, Jean-Pierre

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  2. Marechal, Jean-Didier

    1. IN SILICO AND IN VITRO SCREENING FOR INHIBITION OF CYTOCHROME P450 CYP3A4 BY COMEDICATIONS COMMONLY USED BY PATIENTS WITH CANCER
      Jean-Didier Marechal, Jinglei Yu, Simon Brown, Iouri Kapelioukh, Elaine M. Rankin, C. Roland Wolf, Gordon C. K. Roberts, Mark. J. I. Paine and Michael J. Sutcliffe
      Drug Metabolism and Disposition April 2006, 34 (4) 534-538; DOI: https://doi.org/10.1124/dmd.105.007625

  3. May, Melissa J.

    1. DEPENDENCE OF NELFINAVIR BRAIN UPTAKE ON DOSE AND TISSUE CONCENTRATIONS OF THE SELECTIVE P-GLYCOPROTEIN INHIBITOR ZOSUQUIDAR IN RATS
      Bradley D. Anderson, Melissa J. May, Sherri Jordan, Lin Song, Michael J. Roberts and Markos Leggas
      Drug Metabolism and Disposition April 2006, 34 (4) 653-659; DOI: https://doi.org/10.1124/dmd.105.006536

  4. Meissner, Konrad

    1. EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)
      Henriette E. Meyer zu Schwabedissen, Markus Grube, Annette Dreisbach, Gabriele Jedlitschky, Konrad Meissner, Knud Linnemann, Christoph Fusch, Christoph A. Ritter, Uwe Völker and Heyo K. Kroemer
      Drug Metabolism and Disposition April 2006, 34 (4) 524-533; DOI: https://doi.org/10.1124/dmd.105.007591

  5. Merino, Gracia

    1. BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2) TRANSPORTS FLUOROQUINOLONE ANTIBIOTICS AND AFFECTS THEIR ORAL AVAILABILITY, PHARMACOKINETICS, AND MILK SECRETION
      Gracia Merino, Ana I. Álvarez, Mivis M. Pulido, Antonio J. Molina, Alfred H. Schinkel and Julio G. Prieto
      Drug Metabolism and Disposition April 2006, 34 (4) 690-695; DOI: https://doi.org/10.1124/dmd.105.008219

  6. Meunier, Viviane

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  7. Miwa, Gerald T.

    1. INVESTIGATION OF DRUG-DRUG INTERACTION POTENTIAL OF BORTEZOMIB IN VIVO IN FEMALE SPRAGUE-DAWLEY RATS AND IN VITRO IN HUMAN LIVER MICROSOMES
      Chuang Lu, Richard Gallegos, Ping Li, Cindy Q. Xia, Sandeepraj Pusalkar, Vinita Uttamsingh, Darrell Nix, Gerald T. Miwa and Liang-Shang Gan
      Drug Metabolism and Disposition April 2006, 34 (4) 702-708; DOI: https://doi.org/10.1124/dmd.105.008060

  8. Miyagawa, Shinichi

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  9. Molina, Antonio J.

    1. BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2) TRANSPORTS FLUOROQUINOLONE ANTIBIOTICS AND AFFECTS THEIR ORAL AVAILABILITY, PHARMACOKINETICS, AND MILK SECRETION
      Gracia Merino, Ana I. Álvarez, Mivis M. Pulido, Antonio J. Molina, Alfred H. Schinkel and Julio G. Prieto
      Drug Metabolism and Disposition April 2006, 34 (4) 690-695; DOI: https://doi.org/10.1124/dmd.105.008219

  10. Murakami, Makoto

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

N

  1. Nau, Heinz

    1. S-2-PENTYL-4-PENTYNOIC HYDROXAMIC ACID AND ITS METABOLITE S-2-PENTYL-4-PENTYNOIC ACID IN THE NMRI-EXENCEPHALY-MOUSE MODEL: PHARMACOKINETIC PROFILES, TERATOGENIC EFFECTS, AND HISTONE DEACETYLASE INHIBITION ABILITIES OF FURTHER VALPROIC ACID HYDROXAMATES AND AMIDES
      Daniel Eikel, Katrin Hoffmann, Karolin Zoll, Alfonso Lampen and Heinz Nau
      Drug Metabolism and Disposition April 2006, 34 (4) 612-620; DOI: https://doi.org/10.1124/dmd.105.008078

  2. Nelson, Wendel L.

    1. STEREOCHEMICAL ASPECTS OF ITRACONAZOLE METABOLISM IN VITRO AND IN VIVO
      Kent L. Kunze, Wendel L. Nelson, Evan D. Kharasch, Kenneth E. Thummel and Nina Isoherranen
      Drug Metabolism and Disposition April 2006, 34 (4) 583-590; DOI: https://doi.org/10.1124/dmd.105.008508

  3. Nezasa, Ken-ichi

    1. ALTERED HEPATOBILIARY DISPOSITION OF 5 (AND 6)-CARBOXY-2′,7′-DICHLOROFLUORESCEIN IN Abcg2 (Bcrp1) AND Abcc2 (Mrp2) KNOCKOUT MICE
      Ken-ichi Nezasa, Xianbin Tian, Maciej J. Zamek-Gliszczynski, Nita J. Patel, Thomas J. Raub and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2006, 34 (4) 718-723; DOI: https://doi.org/10.1124/dmd.105.007922

  4. Nishiyama, Masahiko

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  5. Nix, Darrell

    1. INVESTIGATION OF DRUG-DRUG INTERACTION POTENTIAL OF BORTEZOMIB IN VIVO IN FEMALE SPRAGUE-DAWLEY RATS AND IN VITRO IN HUMAN LIVER MICROSOMES
      Chuang Lu, Richard Gallegos, Ping Li, Cindy Q. Xia, Sandeepraj Pusalkar, Vinita Uttamsingh, Darrell Nix, Gerald T. Miwa and Liang-Shang Gan
      Drug Metabolism and Disposition April 2006, 34 (4) 702-708; DOI: https://doi.org/10.1124/dmd.105.008060

  6. Novak, Raymond F.

    1. THE MITOGEN-ACTIVATED PROTEIN KINASE KINASE (MEK) INHIBITOR PD98059 ELEVATES PRIMARY CULTURED RAT HEPATOCYTE GLUTATHIONE LEVELS INDEPENDENT OF INHIBITING MEK
      Sang K. Kim, Mohamed A. Abdelmegeed and Raymond F. Novak
      Drug Metabolism and Disposition April 2006, 34 (4) 683-689; DOI: https://doi.org/10.1124/dmd.105.007666

  7. Nunoya, Kenichi

    1. MUTATIONAL ANALYSIS OF POLAR AMINO ACID RESIDUES WITHIN PREDICTED TRANSMEMBRANE HELICES 10 AND 16 OF MULTIDRUG RESISTANCE PROTEIN 1 (ABCC1): EFFECT ON SUBSTRATE SPECIFICITY
      Da-Wei Zhang, Kenichi Nunoya, Monika Vasa, Hong-Mei Gu, Susan P. C. Cole and Roger G. Deeley
      Drug Metabolism and Disposition April 2006, 34 (4) 539-546; DOI: https://doi.org/10.1124/dmd.105.007740

O

  1. Ogawa, Shinichiro

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  2. Ohdo, Shigehiro

    1. EFFECTS OF HERBAL EXTRACTS ON THE FUNCTION OF HUMAN ORGANIC ANION-TRANSPORTING POLYPEPTIDE OATP-B
      Hiromi Fuchikami, Hiroki Satoh, Masayuki Tsujimoto, Shigehiro Ohdo, Hisakazu Ohtani and Yasufumi Sawada
      Drug Metabolism and Disposition April 2006, 34 (4) 577-582; DOI: https://doi.org/10.1124/dmd.105.007872

  3. Ohtani, Hisakazu

    1. EFFECTS OF HERBAL EXTRACTS ON THE FUNCTION OF HUMAN ORGANIC ANION-TRANSPORTING POLYPEPTIDE OATP-B
      Hiromi Fuchikami, Hiroki Satoh, Masayuki Tsujimoto, Shigehiro Ohdo, Hisakazu Ohtani and Yasufumi Sawada
      Drug Metabolism and Disposition April 2006, 34 (4) 577-582; DOI: https://doi.org/10.1124/dmd.105.007872

  4. Olsson, Ray A.

    1. METABOLISM OF THE A1 ADENOSINE RECEPTOR POSITRON EMISSION TOMOGRAPHY LIGAND [18F]8-CYCLOPENTYL-3-(3-FLUOROPROPYL)-1-PROPYLXANTHINE ([18F]CPFPX) IN RODENTS AND HUMANS
      Dirk Bier, Marcus H. Holschbach, Walter Wutz, Ray A. Olsson and Heinz H. Coenen
      Drug Metabolism and Disposition April 2006, 34 (4) 570-576; DOI: https://doi.org/10.1124/dmd.105.006411

P

  1. Paine, Mark. J. I.

    1. IN SILICO AND IN VITRO SCREENING FOR INHIBITION OF CYTOCHROME P450 CYP3A4 BY COMEDICATIONS COMMONLY USED BY PATIENTS WITH CANCER
      Jean-Didier Marechal, Jinglei Yu, Simon Brown, Iouri Kapelioukh, Elaine M. Rankin, C. Roland Wolf, Gordon C. K. Roberts, Mark. J. I. Paine and Michael J. Sutcliffe
      Drug Metabolism and Disposition April 2006, 34 (4) 534-538; DOI: https://doi.org/10.1124/dmd.105.007625

  2. Patel, Nita J.

    1. ALTERED HEPATOBILIARY DISPOSITION OF 5 (AND 6)-CARBOXY-2′,7′-DICHLOROFLUORESCEIN IN Abcg2 (Bcrp1) AND Abcc2 (Mrp2) KNOCKOUT MICE
      Ken-ichi Nezasa, Xianbin Tian, Maciej J. Zamek-Gliszczynski, Nita J. Patel, Thomas J. Raub and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2006, 34 (4) 718-723; DOI: https://doi.org/10.1124/dmd.105.007922

  3. Pelinski, Lydie

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  4. Phillips, Brian R.

    1. INTERACTIONS OF AMOXICILLIN AND CEFACLOR WITH HUMAN RENAL ORGANIC ANION AND PEPTIDE TRANSPORTERS
      Meng Li, Gail D. Anderson, Brian R. Phillips, Wei Kong, Danny D. Shen and Joanne Wang
      Drug Metabolism and Disposition April 2006, 34 (4) 547-555; DOI: https://doi.org/10.1124/dmd.105.006791

  5. Pikuleva, Irina A.

    1. CHOLESTEROL-METABOLIZING CYTOCHROMES P450
      Irina A. Pikuleva
      Drug Metabolism and Disposition April 2006, 34 (4) 513-520; DOI: https://doi.org/10.1124/dmd.105.008789

  6. Pons, Gérard

    1. IN VITRO AND IN VIVO INHIBITORY EFFECT OF STIRIPENTOL ON CLOBAZAM METABOLISM
      Carole Giraud, Jean-Marc Treluyer, Elisabeth Rey, Catherine Chiron, Jean Vincent, Gérard Pons and Agnès Tran
      Drug Metabolism and Disposition April 2006, 34 (4) 608-611; DOI: https://doi.org/10.1124/dmd.105.007237

  7. Prieto, Julio G.

    1. BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2) TRANSPORTS FLUOROQUINOLONE ANTIBIOTICS AND AFFECTS THEIR ORAL AVAILABILITY, PHARMACOKINETICS, AND MILK SECRETION
      Gracia Merino, Ana I. Álvarez, Mivis M. Pulido, Antonio J. Molina, Alfred H. Schinkel and Julio G. Prieto
      Drug Metabolism and Disposition April 2006, 34 (4) 690-695; DOI: https://doi.org/10.1124/dmd.105.008219

  8. Pulido, Mivis M.

    1. BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2) TRANSPORTS FLUOROQUINOLONE ANTIBIOTICS AND AFFECTS THEIR ORAL AVAILABILITY, PHARMACOKINETICS, AND MILK SECRETION
      Gracia Merino, Ana I. Álvarez, Mivis M. Pulido, Antonio J. Molina, Alfred H. Schinkel and Julio G. Prieto
      Drug Metabolism and Disposition April 2006, 34 (4) 690-695; DOI: https://doi.org/10.1124/dmd.105.008219

  9. Pusalkar, Sandeepraj

    1. INVESTIGATION OF DRUG-DRUG INTERACTION POTENTIAL OF BORTEZOMIB IN VIVO IN FEMALE SPRAGUE-DAWLEY RATS AND IN VITRO IN HUMAN LIVER MICROSOMES
      Chuang Lu, Richard Gallegos, Ping Li, Cindy Q. Xia, Sandeepraj Pusalkar, Vinita Uttamsingh, Darrell Nix, Gerald T. Miwa and Liang-Shang Gan
      Drug Metabolism and Disposition April 2006, 34 (4) 702-708; DOI: https://doi.org/10.1124/dmd.105.008060

R

  1. Rankin, Elaine M.

    1. IN SILICO AND IN VITRO SCREENING FOR INHIBITION OF CYTOCHROME P450 CYP3A4 BY COMEDICATIONS COMMONLY USED BY PATIENTS WITH CANCER
      Jean-Didier Marechal, Jinglei Yu, Simon Brown, Iouri Kapelioukh, Elaine M. Rankin, C. Roland Wolf, Gordon C. K. Roberts, Mark. J. I. Paine and Michael J. Sutcliffe
      Drug Metabolism and Disposition April 2006, 34 (4) 534-538; DOI: https://doi.org/10.1124/dmd.105.007625

  2. Raub, Thomas J.

    1. ALTERED HEPATOBILIARY DISPOSITION OF 5 (AND 6)-CARBOXY-2′,7′-DICHLOROFLUORESCEIN IN Abcg2 (Bcrp1) AND Abcc2 (Mrp2) KNOCKOUT MICE
      Ken-ichi Nezasa, Xianbin Tian, Maciej J. Zamek-Gliszczynski, Nita J. Patel, Thomas J. Raub and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2006, 34 (4) 718-723; DOI: https://doi.org/10.1124/dmd.105.007922

  3. Reed, James R.

    1. AN EVALUATION OF METHODS FOR THE RECONSTITUTION OF CYTOCHROMES P450 AND NADPH P450 REDUCTASE INTO LIPID VESICLES
      James R. Reed, Rusty W. Kelley and Wayne L. Backes
      Drug Metabolism and Disposition April 2006, 34 (4) 660-666; DOI: https://doi.org/10.1124/dmd.105.006825

  4. Rege, Bhaskar

    1. EFFECT OF CHRONIC RENAL INSUFFICIENCY ON HEPATIC AND RENAL UDP-GLUCURONYLTRANSFERASES IN RATS
      Chuanhui Yu, Joseph K. Ritter, Richard J. Krieg, Bhaskar Rege, Thomas H. Karnes and Mohamadi A. Sarkar
      Drug Metabolism and Disposition April 2006, 34 (4) 621-627; DOI: https://doi.org/10.1124/dmd.105.006601

  5. Rehmel, Jessica L. Fayer

    1. INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450
      Jessica L. Fayer Rehmel, James A. Eckstein, Nagy A. Farid, John B. Heim, Steve C. Kasper, Atsushi Kurihara, Steven A. Wrighton and Barbara J. Ring
      Drug Metabolism and Disposition April 2006, 34 (4) 600-607; DOI: https://doi.org/10.1124/dmd.105.007989

  6. Rey, Elisabeth

    1. IN VITRO AND IN VIVO INHIBITORY EFFECT OF STIRIPENTOL ON CLOBAZAM METABOLISM
      Carole Giraud, Jean-Marc Treluyer, Elisabeth Rey, Catherine Chiron, Jean Vincent, Gérard Pons and Agnès Tran
      Drug Metabolism and Disposition April 2006, 34 (4) 608-611; DOI: https://doi.org/10.1124/dmd.105.007237

  7. Reznik, Boris

    1. FETAL MORPHINE METABOLISM AND CLEARANCE ARE CONSTANT DURING LATE GESTATION
      Marianne Garland, Kirsten M. Abildskov, Samantha Taylor, Kenza Benzeroual, Casper S. Caspersen, Sylvia E. Arroyo, Tung-wah Kiu, Boris Reznik, Piper Weldy, Salha S. Daniel and Raymond I. Stark
      Drug Metabolism and Disposition April 2006, 34 (4) 636-646; DOI: https://doi.org/10.1124/dmd.105.007567

  8. Riley, R. J.

    1. RESPONSE TO “BINDING OF DRUGS TO HEPATIC MICROSOMES: COMMENT AND ASSESSMENT OF CURRENT PREDICTION METHODOLOGY WITH RECOMMENDATION FOR IMPROVEMENT”
      R. P. Austin, P. Barton and R. J. Riley
      Drug Metabolism and Disposition April 2006, 34 (4) 727; DOI: https://doi.org/10.1124/dmd.105.009142

  9. Ring, Barbara J.

    1. INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450
      Jessica L. Fayer Rehmel, James A. Eckstein, Nagy A. Farid, John B. Heim, Steve C. Kasper, Atsushi Kurihara, Steven A. Wrighton and Barbara J. Ring
      Drug Metabolism and Disposition April 2006, 34 (4) 600-607; DOI: https://doi.org/10.1124/dmd.105.007989

  10. Ritter, Christoph A.

    1. EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)
      Henriette E. Meyer zu Schwabedissen, Markus Grube, Annette Dreisbach, Gabriele Jedlitschky, Konrad Meissner, Knud Linnemann, Christoph Fusch, Christoph A. Ritter, Uwe Völker and Heyo K. Kroemer
      Drug Metabolism and Disposition April 2006, 34 (4) 524-533; DOI: https://doi.org/10.1124/dmd.105.007591

  11. Ritter, Joseph K.

    1. EFFECT OF CHRONIC RENAL INSUFFICIENCY ON HEPATIC AND RENAL UDP-GLUCURONYLTRANSFERASES IN RATS
      Chuanhui Yu, Joseph K. Ritter, Richard J. Krieg, Bhaskar Rege, Thomas H. Karnes and Mohamadi A. Sarkar
      Drug Metabolism and Disposition April 2006, 34 (4) 621-627; DOI: https://doi.org/10.1124/dmd.105.006601

  12. Roberts, Gordon C. K.

    1. IN SILICO AND IN VITRO SCREENING FOR INHIBITION OF CYTOCHROME P450 CYP3A4 BY COMEDICATIONS COMMONLY USED BY PATIENTS WITH CANCER
      Jean-Didier Marechal, Jinglei Yu, Simon Brown, Iouri Kapelioukh, Elaine M. Rankin, C. Roland Wolf, Gordon C. K. Roberts, Mark. J. I. Paine and Michael J. Sutcliffe
      Drug Metabolism and Disposition April 2006, 34 (4) 534-538; DOI: https://doi.org/10.1124/dmd.105.007625

  13. Roberts, Michael J.

    1. DEPENDENCE OF NELFINAVIR BRAIN UPTAKE ON DOSE AND TISSUE CONCENTRATIONS OF THE SELECTIVE P-GLYCOPROTEIN INHIBITOR ZOSUQUIDAR IN RATS
      Bradley D. Anderson, Melissa J. May, Sherri Jordan, Lin Song, Michael J. Roberts and Markos Leggas
      Drug Metabolism and Disposition April 2006, 34 (4) 653-659; DOI: https://doi.org/10.1124/dmd.105.006536

S

  1. Sadoun, Freddy

    1. IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
      Wassim Daher, Lydie Pelinski, Sylvie Klieber, Freddy Sadoun, Viviane Meunier, Martine Bourrié, Christophe Biot, François Guillou, Gérard Fabre, Jacques Brocard, Laurent Fraisse, Jean-Pierre Maffrand, Jamal Khalife and Daniel Dive
      Drug Metabolism and Disposition April 2006, 34 (4) 667-682; DOI: https://doi.org/10.1124/dmd.104.003202

  2. Sarkar, Mohamadi A.

    1. EFFECT OF CHRONIC RENAL INSUFFICIENCY ON HEPATIC AND RENAL UDP-GLUCURONYLTRANSFERASES IN RATS
      Chuanhui Yu, Joseph K. Ritter, Richard J. Krieg, Bhaskar Rege, Thomas H. Karnes and Mohamadi A. Sarkar
      Drug Metabolism and Disposition April 2006, 34 (4) 621-627; DOI: https://doi.org/10.1124/dmd.105.006601

  3. Satoh, Fumiyasu

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  4. Satoh, Hiroki

    1. EFFECTS OF HERBAL EXTRACTS ON THE FUNCTION OF HUMAN ORGANIC ANION-TRANSPORTING POLYPEPTIDE OATP-B
      Hiromi Fuchikami, Hiroki Satoh, Masayuki Tsujimoto, Shigehiro Ohdo, Hisakazu Ohtani and Yasufumi Sawada
      Drug Metabolism and Disposition April 2006, 34 (4) 577-582; DOI: https://doi.org/10.1124/dmd.105.007872

  5. Sawada, Yasufumi

    1. EFFECTS OF HERBAL EXTRACTS ON THE FUNCTION OF HUMAN ORGANIC ANION-TRANSPORTING POLYPEPTIDE OATP-B
      Hiromi Fuchikami, Hiroki Satoh, Masayuki Tsujimoto, Shigehiro Ohdo, Hisakazu Ohtani and Yasufumi Sawada
      Drug Metabolism and Disposition April 2006, 34 (4) 577-582; DOI: https://doi.org/10.1124/dmd.105.007872

  6. Schinkel, Alfred H.

    1. BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2) TRANSPORTS FLUOROQUINOLONE ANTIBIOTICS AND AFFECTS THEIR ORAL AVAILABILITY, PHARMACOKINETICS, AND MILK SECRETION
      Gracia Merino, Ana I. Álvarez, Mivis M. Pulido, Antonio J. Molina, Alfred H. Schinkel and Julio G. Prieto
      Drug Metabolism and Disposition April 2006, 34 (4) 690-695; DOI: https://doi.org/10.1124/dmd.105.008219

  7. Schuetz, John D.

    1. CHARACTERIZATION OF TRANSPORT PROTEIN EXPRESSION IN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN (MRP) 2-DEFICIENT RATS
      Brendan M. Johnson, Peijin Zhang, John D. Schuetz and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2006, 34 (4) 556-562; DOI: https://doi.org/10.1124/dmd.105.005793

  8. Shen, Danny D.

    1. INTERACTIONS OF AMOXICILLIN AND CEFACLOR WITH HUMAN RENAL ORGANIC ANION AND PEPTIDE TRANSPORTERS
      Meng Li, Gail D. Anderson, Brian R. Phillips, Wei Kong, Danny D. Shen and Joanne Wang
      Drug Metabolism and Disposition April 2006, 34 (4) 547-555; DOI: https://doi.org/10.1124/dmd.105.006791

  9. Shibata, Nobuo

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  10. Shin, Jae-Gook

    1. INHIBITORY EFFECTS OF FRUIT JUICES ON CYP3A ACTIVITY
      Hyunmi Kim, Yune-Jung Yoon, Ji-Hong Shon, In-June Cha, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition April 2006, 34 (4) 521-523; DOI: https://doi.org/10.1124/dmd.105.007930

  11. Shon, Ji-Hong

    1. INHIBITORY EFFECTS OF FRUIT JUICES ON CYP3A ACTIVITY
      Hyunmi Kim, Yune-Jung Yoon, Ji-Hong Shon, In-June Cha, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition April 2006, 34 (4) 521-523; DOI: https://doi.org/10.1124/dmd.105.007930

  12. Smith, Evan

    1. IN VITRO METABOLIC ACTIVATION OF THIABENDAZOLE VIA 5-HYDROXYTHIABENDAZOLE: IDENTIFICATION OF A GLUTATHIONE CONJUGATE OF 5-HYDROXYTHIABENDAZOLE
      Deepak Dalvie, Evan Smith, Alan Deese and Stephen Bowlin
      Drug Metabolism and Disposition April 2006, 34 (4) 709-717; DOI: https://doi.org/10.1124/dmd.105.008094

  13. Song, Lin

    1. DEPENDENCE OF NELFINAVIR BRAIN UPTAKE ON DOSE AND TISSUE CONCENTRATIONS OF THE SELECTIVE P-GLYCOPROTEIN INHIBITOR ZOSUQUIDAR IN RATS
      Bradley D. Anderson, Melissa J. May, Sherri Jordan, Lin Song, Michael J. Roberts and Markos Leggas
      Drug Metabolism and Disposition April 2006, 34 (4) 653-659; DOI: https://doi.org/10.1124/dmd.105.006536

  14. Stark, Raymond I.

    1. FETAL MORPHINE METABOLISM AND CLEARANCE ARE CONSTANT DURING LATE GESTATION
      Marianne Garland, Kirsten M. Abildskov, Samantha Taylor, Kenza Benzeroual, Casper S. Caspersen, Sylvia E. Arroyo, Tung-wah Kiu, Boris Reznik, Piper Weldy, Salha S. Daniel and Raymond I. Stark
      Drug Metabolism and Disposition April 2006, 34 (4) 636-646; DOI: https://doi.org/10.1124/dmd.105.007567

  15. Su, Ai-Duen

    1. IDENTIFICATION OF HUMAN LIVER CYTOCHROME P450 ENZYMES RESPONSIBLE FOR THE METABOLISM OF LONAFARNIB (SARASAR)
      Anima Ghosal, Swapan K. Chowdhury, Wei Tong, Neil Hapangama, Yuan Yuan, Ai-Duen Su and Shmuel Zbaida
      Drug Metabolism and Disposition April 2006, 34 (4) 628-635; DOI: https://doi.org/10.1124/dmd.105.007906

  16. Sutcliffe, Michael J.

    1. IN SILICO AND IN VITRO SCREENING FOR INHIBITION OF CYTOCHROME P450 CYP3A4 BY COMEDICATIONS COMMONLY USED BY PATIENTS WITH CANCER
      Jean-Didier Marechal, Jinglei Yu, Simon Brown, Iouri Kapelioukh, Elaine M. Rankin, C. Roland Wolf, Gordon C. K. Roberts, Mark. J. I. Paine and Michael J. Sutcliffe
      Drug Metabolism and Disposition April 2006, 34 (4) 534-538; DOI: https://doi.org/10.1124/dmd.105.007625

T

  1. Tagawa, Yoh-ichi

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  2. Tanaka, Satoru

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  3. Taylor, Samantha

    1. FETAL MORPHINE METABOLISM AND CLEARANCE ARE CONSTANT DURING LATE GESTATION
      Marianne Garland, Kirsten M. Abildskov, Samantha Taylor, Kenza Benzeroual, Casper S. Caspersen, Sylvia E. Arroyo, Tung-wah Kiu, Boris Reznik, Piper Weldy, Salha S. Daniel and Raymond I. Stark
      Drug Metabolism and Disposition April 2006, 34 (4) 636-646; DOI: https://doi.org/10.1124/dmd.105.007567

  4. Thummel, Kenneth E.

    1. STEREOCHEMICAL ASPECTS OF ITRACONAZOLE METABOLISM IN VITRO AND IN VIVO
      Kent L. Kunze, Wendel L. Nelson, Evan D. Kharasch, Kenneth E. Thummel and Nina Isoherranen
      Drug Metabolism and Disposition April 2006, 34 (4) 583-590; DOI: https://doi.org/10.1124/dmd.105.008508

  5. Tian, Xianbin

    1. ALTERED HEPATOBILIARY DISPOSITION OF 5 (AND 6)-CARBOXY-2′,7′-DICHLOROFLUORESCEIN IN Abcg2 (Bcrp1) AND Abcc2 (Mrp2) KNOCKOUT MICE
      Ken-ichi Nezasa, Xianbin Tian, Maciej J. Zamek-Gliszczynski, Nita J. Patel, Thomas J. Raub and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2006, 34 (4) 718-723; DOI: https://doi.org/10.1124/dmd.105.007922

  6. Tomioka, Eisuke

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  7. Tong, Wei

    1. IDENTIFICATION OF HUMAN LIVER CYTOCHROME P450 ENZYMES RESPONSIBLE FOR THE METABOLISM OF LONAFARNIB (SARASAR)
      Anima Ghosal, Swapan K. Chowdhury, Wei Tong, Neil Hapangama, Yuan Yuan, Ai-Duen Su and Shmuel Zbaida
      Drug Metabolism and Disposition April 2006, 34 (4) 628-635; DOI: https://doi.org/10.1124/dmd.105.007906

  8. Tran, Agnès

    1. IN VITRO AND IN VIVO INHIBITORY EFFECT OF STIRIPENTOL ON CLOBAZAM METABOLISM
      Carole Giraud, Jean-Marc Treluyer, Elisabeth Rey, Catherine Chiron, Jean Vincent, Gérard Pons and Agnès Tran
      Drug Metabolism and Disposition April 2006, 34 (4) 608-611; DOI: https://doi.org/10.1124/dmd.105.007237

  9. Treluyer, Jean-Marc

    1. IN VITRO AND IN VIVO INHIBITORY EFFECT OF STIRIPENTOL ON CLOBAZAM METABOLISM
      Carole Giraud, Jean-Marc Treluyer, Elisabeth Rey, Catherine Chiron, Jean Vincent, Gérard Pons and Agnès Tran
      Drug Metabolism and Disposition April 2006, 34 (4) 608-611; DOI: https://doi.org/10.1124/dmd.105.007237

  10. Tsujimoto, Masayuki

    1. EFFECTS OF HERBAL EXTRACTS ON THE FUNCTION OF HUMAN ORGANIC ANION-TRANSPORTING POLYPEPTIDE OATP-B
      Hiromi Fuchikami, Hiroki Satoh, Masayuki Tsujimoto, Shigehiro Ohdo, Hisakazu Ohtani and Yasufumi Sawada
      Drug Metabolism and Disposition April 2006, 34 (4) 577-582; DOI: https://doi.org/10.1124/dmd.105.007872

  11. Tsutsui, Masaru

    1. CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM
      Masaru Tsutsui, Shinichiro Ogawa, Yoichi Inada, Eisuke Tomioka, Akiko Kamiyoshi, Satoru Tanaka, Tomoyuki Kishida, Masahiko Nishiyama, Makoto Murakami, Junji Kuroda, Yasuhiko Hashikura, Shinichi Miyagawa, Fumiyasu Satoh, Nobuo Shibata and Yoh-ichi Tagawa
      Drug Metabolism and Disposition April 2006, 34 (4) 696-701; DOI: https://doi.org/10.1124/dmd.105.007674

  12. Tyndale, Rachel F.

    1. INDUCTION AND RECOVERY TIME COURSE OF RAT BRAIN CYP2E1 AFTER NICOTINE TREATMENT
      Meenal Joshi and Rachel F. Tyndale
      Drug Metabolism and Disposition April 2006, 34 (4) 647-652; DOI: https://doi.org/10.1124/dmd.105.008029

U

  1. Uttamsingh, Vinita

    1. INVESTIGATION OF DRUG-DRUG INTERACTION POTENTIAL OF BORTEZOMIB IN VIVO IN FEMALE SPRAGUE-DAWLEY RATS AND IN VITRO IN HUMAN LIVER MICROSOMES
      Chuang Lu, Richard Gallegos, Ping Li, Cindy Q. Xia, Sandeepraj Pusalkar, Vinita Uttamsingh, Darrell Nix, Gerald T. Miwa and Liang-Shang Gan
      Drug Metabolism and Disposition April 2006, 34 (4) 702-708; DOI: https://doi.org/10.1124/dmd.105.008060

V

  1. van de Kerkhof, Esther G.

    1. EMPIRICAL VALIDATION OF A RAT IN VITRO ORGAN SLICE MODEL AS A TOOL FOR IN VIVO CLEARANCE PREDICTION
      Inge A. M. de Graaf, Ruben de Kanter, Marina H. de Jager, Raquel Camacho, Elise Langenkamp, Esther G. van de Kerkhof and Geny M. M. Groothuis
      Drug Metabolism and Disposition April 2006, 34 (4) 591-599; DOI: https://doi.org/10.1124/dmd.105.006726

  2. Vasa, Monika

    1. MUTATIONAL ANALYSIS OF POLAR AMINO ACID RESIDUES WITHIN PREDICTED TRANSMEMBRANE HELICES 10 AND 16 OF MULTIDRUG RESISTANCE PROTEIN 1 (ABCC1): EFFECT ON SUBSTRATE SPECIFICITY
      Da-Wei Zhang, Kenichi Nunoya, Monika Vasa, Hong-Mei Gu, Susan P. C. Cole and Roger G. Deeley
      Drug Metabolism and Disposition April 2006, 34 (4) 539-546; DOI: https://doi.org/10.1124/dmd.105.007740

  3. Vincent, Jean

    1. IN VITRO AND IN VIVO INHIBITORY EFFECT OF STIRIPENTOL ON CLOBAZAM METABOLISM
      Carole Giraud, Jean-Marc Treluyer, Elisabeth Rey, Catherine Chiron, Jean Vincent, Gérard Pons and Agnès Tran
      Drug Metabolism and Disposition April 2006, 34 (4) 608-611; DOI: https://doi.org/10.1124/dmd.105.007237

  4. Völker, Uwe

    1. EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)
      Henriette E. Meyer zu Schwabedissen, Markus Grube, Annette Dreisbach, Gabriele Jedlitschky, Konrad Meissner, Knud Linnemann, Christoph Fusch, Christoph A. Ritter, Uwe Völker and Heyo K. Kroemer
      Drug Metabolism and Disposition April 2006, 34 (4) 524-533; DOI: https://doi.org/10.1124/dmd.105.007591

W

  1. Wang, Joanne

    1. INTERACTIONS OF AMOXICILLIN AND CEFACLOR WITH HUMAN RENAL ORGANIC ANION AND PEPTIDE TRANSPORTERS
      Meng Li, Gail D. Anderson, Brian R. Phillips, Wei Kong, Danny D. Shen and Joanne Wang
      Drug Metabolism and Disposition April 2006, 34 (4) 547-555; DOI: https://doi.org/10.1124/dmd.105.006791

  2. Weldy, Piper

    1. FETAL MORPHINE METABOLISM AND CLEARANCE ARE CONSTANT DURING LATE GESTATION
      Marianne Garland, Kirsten M. Abildskov, Samantha Taylor, Kenza Benzeroual, Casper S. Caspersen, Sylvia E. Arroyo, Tung-wah Kiu, Boris Reznik, Piper Weldy, Salha S. Daniel and Raymond I. Stark
      Drug Metabolism and Disposition April 2006, 34 (4) 636-646; DOI: https://doi.org/10.1124/dmd.105.007567

  3. Wolf, C. Roland

    1. IN SILICO AND IN VITRO SCREENING FOR INHIBITION OF CYTOCHROME P450 CYP3A4 BY COMEDICATIONS COMMONLY USED BY PATIENTS WITH CANCER
      Jean-Didier Marechal, Jinglei Yu, Simon Brown, Iouri Kapelioukh, Elaine M. Rankin, C. Roland Wolf, Gordon C. K. Roberts, Mark. J. I. Paine and Michael J. Sutcliffe
      Drug Metabolism and Disposition April 2006, 34 (4) 534-538; DOI: https://doi.org/10.1124/dmd.105.007625

  4. Wrighton, Steven A.

    1. INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450
      Jessica L. Fayer Rehmel, James A. Eckstein, Nagy A. Farid, John B. Heim, Steve C. Kasper, Atsushi Kurihara, Steven A. Wrighton and Barbara J. Ring
      Drug Metabolism and Disposition April 2006, 34 (4) 600-607; DOI: https://doi.org/10.1124/dmd.105.007989

  5. Wutz, Walter

    1. METABOLISM OF THE A1 ADENOSINE RECEPTOR POSITRON EMISSION TOMOGRAPHY LIGAND [18F]8-CYCLOPENTYL-3-(3-FLUOROPROPYL)-1-PROPYLXANTHINE ([18F]CPFPX) IN RODENTS AND HUMANS
      Dirk Bier, Marcus H. Holschbach, Walter Wutz, Ray A. Olsson and Heinz H. Coenen
      Drug Metabolism and Disposition April 2006, 34 (4) 570-576; DOI: https://doi.org/10.1124/dmd.105.006411

X

  1. Xia, Cindy Q.

    1. INVESTIGATION OF DRUG-DRUG INTERACTION POTENTIAL OF BORTEZOMIB IN VIVO IN FEMALE SPRAGUE-DAWLEY RATS AND IN VITRO IN HUMAN LIVER MICROSOMES
      Chuang Lu, Richard Gallegos, Ping Li, Cindy Q. Xia, Sandeepraj Pusalkar, Vinita Uttamsingh, Darrell Nix, Gerald T. Miwa and Liang-Shang Gan
      Drug Metabolism and Disposition April 2006, 34 (4) 702-708; DOI: https://doi.org/10.1124/dmd.105.008060

Y

  1. Yoon, Yune-Jung

    1. INHIBITORY EFFECTS OF FRUIT JUICES ON CYP3A ACTIVITY
      Hyunmi Kim, Yune-Jung Yoon, Ji-Hong Shon, In-June Cha, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition April 2006, 34 (4) 521-523; DOI: https://doi.org/10.1124/dmd.105.007930

  2. Yu, Chuanhui

    1. EFFECT OF CHRONIC RENAL INSUFFICIENCY ON HEPATIC AND RENAL UDP-GLUCURONYLTRANSFERASES IN RATS
      Chuanhui Yu, Joseph K. Ritter, Richard J. Krieg, Bhaskar Rege, Thomas H. Karnes and Mohamadi A. Sarkar
      Drug Metabolism and Disposition April 2006, 34 (4) 621-627; DOI: https://doi.org/10.1124/dmd.105.006601

  3. Yu, Jinglei

    1. IN SILICO AND IN VITRO SCREENING FOR INHIBITION OF CYTOCHROME P450 CYP3A4 BY COMEDICATIONS COMMONLY USED BY PATIENTS WITH CANCER
      Jean-Didier Marechal, Jinglei Yu, Simon Brown, Iouri Kapelioukh, Elaine M. Rankin, C. Roland Wolf, Gordon C. K. Roberts, Mark. J. I. Paine and Michael J. Sutcliffe
      Drug Metabolism and Disposition April 2006, 34 (4) 534-538; DOI: https://doi.org/10.1124/dmd.105.007625

  4. Yuan, Yuan

    1. IDENTIFICATION OF HUMAN LIVER CYTOCHROME P450 ENZYMES RESPONSIBLE FOR THE METABOLISM OF LONAFARNIB (SARASAR)
      Anima Ghosal, Swapan K. Chowdhury, Wei Tong, Neil Hapangama, Yuan Yuan, Ai-Duen Su and Shmuel Zbaida
      Drug Metabolism and Disposition April 2006, 34 (4) 628-635; DOI: https://doi.org/10.1124/dmd.105.007906

Z

  1. Zamek-Gliszczynski, Maciej J.

    1. ALTERED HEPATOBILIARY DISPOSITION OF 5 (AND 6)-CARBOXY-2′,7′-DICHLOROFLUORESCEIN IN Abcg2 (Bcrp1) AND Abcc2 (Mrp2) KNOCKOUT MICE
      Ken-ichi Nezasa, Xianbin Tian, Maciej J. Zamek-Gliszczynski, Nita J. Patel, Thomas J. Raub and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2006, 34 (4) 718-723; DOI: https://doi.org/10.1124/dmd.105.007922

  2. Zbaida, Shmuel

    1. IDENTIFICATION OF HUMAN LIVER CYTOCHROME P450 ENZYMES RESPONSIBLE FOR THE METABOLISM OF LONAFARNIB (SARASAR)
      Anima Ghosal, Swapan K. Chowdhury, Wei Tong, Neil Hapangama, Yuan Yuan, Ai-Duen Su and Shmuel Zbaida
      Drug Metabolism and Disposition April 2006, 34 (4) 628-635; DOI: https://doi.org/10.1124/dmd.105.007906

  3. Zhang, Da-Wei

    1. MUTATIONAL ANALYSIS OF POLAR AMINO ACID RESIDUES WITHIN PREDICTED TRANSMEMBRANE HELICES 10 AND 16 OF MULTIDRUG RESISTANCE PROTEIN 1 (ABCC1): EFFECT ON SUBSTRATE SPECIFICITY
      Da-Wei Zhang, Kenichi Nunoya, Monika Vasa, Hong-Mei Gu, Susan P. C. Cole and Roger G. Deeley
      Drug Metabolism and Disposition April 2006, 34 (4) 539-546; DOI: https://doi.org/10.1124/dmd.105.007740

  4. Zhang, Peijin

    1. CHARACTERIZATION OF TRANSPORT PROTEIN EXPRESSION IN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN (MRP) 2-DEFICIENT RATS
      Brendan M. Johnson, Peijin Zhang, John D. Schuetz and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2006, 34 (4) 556-562; DOI: https://doi.org/10.1124/dmd.105.005793

  5. Zoll, Karolin

    1. S-2-PENTYL-4-PENTYNOIC HYDROXAMIC ACID AND ITS METABOLITE S-2-PENTYL-4-PENTYNOIC ACID IN THE NMRI-EXENCEPHALY-MOUSE MODEL: PHARMACOKINETIC PROFILES, TERATOGENIC EFFECTS, AND HISTONE DEACETYLASE INHIBITION ABILITIES OF FURTHER VALPROIC ACID HYDROXAMATES AND AMIDES
      Daniel Eikel, Katrin Hoffmann, Karolin Zoll, Alfonso Lampen and Heinz Nau
      Drug Metabolism and Disposition April 2006, 34 (4) 612-620; DOI: https://doi.org/10.1124/dmd.105.008078

  6. zu Schwabedissen, Henriette E. Meyer

    1. EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)
      Henriette E. Meyer zu Schwabedissen, Markus Grube, Annette Dreisbach, Gabriele Jedlitschky, Konrad Meissner, Knud Linnemann, Christoph Fusch, Christoph A. Ritter, Uwe Völker and Heyo K. Kroemer
      Drug Metabolism and Disposition April 2006, 34 (4) 524-533; DOI: https://doi.org/10.1124/dmd.105.007591
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