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Research ArticleArticle

COMPARISON OF METHODS FOR THE PREDICTION OF THE METABOLIC SITES FOR CYP3A4-MEDIATED METABOLIC REACTIONS

Diansong Zhou, Lovisa Afzelius, Scott W. Grimm, Tommy B. Andersson, Randy J. Zauhar and Ismael Zamora
Drug Metabolism and Disposition June 2006, 34 (6) 976-983; DOI: https://doi.org/10.1124/dmd.105.008631
Diansong Zhou
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Lovisa Afzelius
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Scott W. Grimm
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Tommy B. Andersson
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Randy J. Zauhar
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Ismael Zamora
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Article Information

vol. 34 no. 6 976-983
DOI 
https://doi.org/10.1124/dmd.105.008631
PubMed 
16540587

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received December 2, 2005
  • Accepted March 10, 2006
  • Published online May 18, 2006.

Article Versions

  • Earlier version (March 15, 2006 - 10:35).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Diansong Zhou,
  2. Lovisa Afzelius,
  3. Scott W. Grimm,
  4. Tommy B. Andersson,
  5. Randy J. Zauhar and
  6. Ismael Zamora
  1. Department of Drug Metabolism and Pharmacokinetics, AstraZeneca Pharmaceuticals, Wilmington, Delaware (D.Z., S.W.G.); Department of Chemistry & Biochemistry, the University of Sciences in Philadelphia, Philadelphia, Pennsylvania (D.Z., R.J.Z.); Department of Drug Metabolism and Pharmacokinetics & Bioanalytical Chemistry, AstraZeneca R&D, Molndal, Sweden (L.A., T.B.A.); Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (T.B.A.); Lead Molecular Design, Barcelona, Spain (I.Z.); and GRIB-IMIM, Barcelona, Spain (I.Z.)
  1. Address correspondence to:
    Diansong Zhou, Department of Drug Metabolism and Pharmacokinetics, AstraZeneca Pharmaceuticals, 1800 Concord Pike, Wilmington, DE 19810. E-mail: diansong.zhou{at}AstraZeneca.com
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Drug Metabolism and Disposition: 34 (6)
Drug Metabolism and Disposition
Vol. 34, Issue 6
1 Jun 2006
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Research ArticleArticle

COMPARISON OF METHODS FOR THE PREDICTION OF THE METABOLIC SITES FOR CYP3A4-MEDIATED METABOLIC REACTIONS

Diansong Zhou, Lovisa Afzelius, Scott W. Grimm, Tommy B. Andersson, Randy J. Zauhar and Ismael Zamora
Drug Metabolism and Disposition June 1, 2006, 34 (6) 976-983; DOI: https://doi.org/10.1124/dmd.105.008631

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Research ArticleArticle

COMPARISON OF METHODS FOR THE PREDICTION OF THE METABOLIC SITES FOR CYP3A4-MEDIATED METABOLIC REACTIONS

Diansong Zhou, Lovisa Afzelius, Scott W. Grimm, Tommy B. Andersson, Randy J. Zauhar and Ismael Zamora
Drug Metabolism and Disposition June 1, 2006, 34 (6) 976-983; DOI: https://doi.org/10.1124/dmd.105.008631
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