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Research ArticleArticle

PREDOMINANT CONTRIBUTION OF OATP1B3 TO THE HEPATIC UPTAKE OF TELMISARTAN, AN ANGIOTENSIN II RECEPTOR ANTAGONIST, IN HUMANS

Naoki Ishiguro, Kazuya Maeda, Wataru Kishimoto, Asami Saito, Akiko Harada, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
Drug Metabolism and Disposition July 2006, 34 (7) 1109-1115; DOI: https://doi.org/10.1124/dmd.105.009175

Article Information

vol. 34 no. 7 1109-1115
DOI 
https://doi.org/10.1124/dmd.105.009175
PubMed 
16611857
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online June 21, 2006.

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The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Naoki Ishiguro,
  2. Kazuya Maeda,
  3. Wataru Kishimoto,
  4. Asami Saito,
  5. Akiko Harada,
  6. Thomas Ebner,
  7. Willy Roth,
  8. Takashi Igarashi and
  9. Yuichi Sugiyama
  1. Department of Pharmacokinetics and Non-Clinical Safety, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co., Ltd., Hyogo, Japan (N.I., W.K., A.S., A.H., T.I.); Department of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo, Japan (K.M., Y.S.); and Department of Pharmacokinetics and Drug Metabolism, Boehringer Ingelheim Pharma KG, Biberach on der Riss, Germany (T.E., W.R.)
  1. Address correspondence to:
    Dr. Yuichi Sugiyama, Department of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. E-mail: sugiyama{at}mol.f.u-tokyo.ac.jp
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Research ArticleArticle

PREDOMINANT CONTRIBUTION OF OATP1B3 TO THE HEPATIC UPTAKE OF TELMISARTAN, AN ANGIOTENSIN II RECEPTOR ANTAGONIST, IN HUMANS

Naoki Ishiguro, Kazuya Maeda, Wataru Kishimoto, Asami Saito, Akiko Harada, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
Drug Metabolism and Disposition July 1, 2006, 34 (7) 1109-1115; DOI: https://doi.org/10.1124/dmd.105.009175
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